JPH06509816A - Flavored composition - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

[Detailed description of the invention] Flavored composition Industrial applications and conventional technology The invention applies to the fragrance industry and the cosmetics industry, and in particular to bob yves odorants and antiperspirants. Concerning the agent industry.

The main functions of Bob-Eve Odorant or antiperspirant are bacterial decomposition and sweat-forming substances. This function prevents body odor caused by oxidation of organic substances. Traditionally, deodorants mask body odor. , and contains substances that can inhibit the growth of bacteria that cause sweat to deteriorate. , on the other hand, antiperspirants contain compositions that reduce sweating and at the same time have a bactericidal effect.

In the case of these two examples, these days, consumers would rather have natural or natural-identical (i.e. Synthetic, but based on substances whose structure corresponds to naturally occurring compositions) There is a tendency to favor deodorant products based on active ingredients. this request In hobbe odorants and antiperspirants, often allergic Certain commonly used bactericidal, antibacterial, and antiperspirant substances are inhibited and They are intended to be replaced by natural active ingredients. Therefore, over the past few years, Do not rely on traditional disinfectants (to ensure sufficient deodorization This may be due to the presence of fragrance compositions containing carefully selected fragrance ingredients. The development of new products has been confirmed [e.g., G., W., Holzner in Aer. See osol Report 25.354 (1986), also published See EP 451 889, which describes fragrances of synthetic or natural origin. This book contains a completely complete analysis of the state of the art in the field of the bactericidal action of food ingredients. Another special example of a composition exhibiting this tendency is described in European Patent No. 433132. The composition described in Antibacterial activity and antibacterial activity dispersed in the aqueous phase stabilized using a lipid layer with medial lipids. and/or contain essential oils that have antifungal properties.

On the other hand, the desirable Bob-Eve odorants have as wide a spectrum of bactericidal action as possible. It must be possible to identify any microbial growth present on the skin. must be prevented as effectively as possible.

However, deodorant products based on fragrance substances are effective against all types of microorganisms. It is well known that they do not have the same effect.

The object of the present invention can originally contribute to solving this problem.

Description of the invention The present invention shows that cationic phospholipids have an antimicrobial effect ("PBAA"). and a fatty alcohol having from 10 to 22 carbon atoms. A fragrance composition characterized by:

In fact, as can be confirmed from the examples given below, these three compounds are present in perfume compositions. The simultaneous presence of two components suppresses the actions of a wide variety of microorganisms. and the composition is particularly suitable for use in deodorants and antiperspirants. It has been found that this composition imparts significant deodorant power which represents an advantage. It was issued. Surprisingly, the presence of "PBAA" and fatty alcohol has a synergistic effect. The effect of cationic phospholipids is enhanced by the method of the fruit, and the composition according to the state of the art It was confirmed that an improved perfume composition was obtained.

Furthermore, the composition according to the invention can be applied to aluminum, which is commonly used as an effective antiperspirant material. important without relying on the use of aluminum or aluminum and zirconium salts It was confirmed that it has a strong antiperspirant effect.

Cationic phospholipids are commonly used in cosmetics as emulsifiers or softeners, It is a substance consistent with nature. However, to the best of applicant's knowledge, Bob Eve Odra There is no mention in the literature regarding the use of these substances in antiperspirants or antiperspirants. the At least 80% antimicrobial as measured by the direct spray method described above Perfume additive according to advantageous embodiment a of the invention, characterized by exhibiting an action When the added composition is used on the skin, there is no sweat odor for at least 12 hours. , and has until now been commonly consumed as a fungicide or bacteriostatic agent. Hexachlorophene, dichlorophenol, trichlorosalicylanilide, Trichlorosalicylanilide (TBS), Tetrachlorosalicylanilide (TC 3A), trichlorocarbanilide (TCC) or Irgasan DP-300 (I rgasan *DP-300) (Ciba-Geig! It has been newly discovered that it is possible to avoid the use of substances such as /)　).

The composition according to the invention is suitable for deodorant compositions and compositions using conventional active elements. It has distinct advantages over antiperspirant and antiperspirant compositions. In fact, cationic phospholipids are non-toxic. It is a biodegradable substance and does not cause any irritating effects on the skin; It has a softening effect on the skin.

According to an advantageous embodiment according to the invention, in this case phospholipids of synthetic origin, i.e. Phospholipids corresponding to those found in nature may be used. Good results indicate that the formula [where R represents a linoleamidopropyl group or a cocamidopropyl group, and x+y is 3 It was confirmed that this can be obtained when using the phospholipid shown in a certain example.

Such phospholipids are available on the market, namely phospholipid PTC and phospholipid EFA (Mo Mona Industry Inc., United States (USA)) Obtained below.

The phospholipids mentioned above are commonly used in conventional deodorant or antiperspirant based deodorants or antiperspirants. may be added directly to the formulation. Examples of such formulations are described below. Advantageously, Li The phospholipids are 0% based on the weight of the flavored composition in which they are incorporated. ．． It is added at a concentration of 0.05 to 5% by weight. Fatty alcohols can be added to the perfume composition according to the invention. fatty alcohols present in the product, preferably having 14 to 18 carbon atoms; is used. Cetyl alcohol and myristyl alcohol are suitable for this use. It has been found to be particularly advantageous.

According to an advantageous embodiment, the fatty alcohol is present in an amount of 0.0 based on the weight of the perfume composition. It is used in concentrations between 2 and 2% by weight.

On the contrary, perfume bases with antimicrobial action, or 'PBAA ” is preferably added in a concentration between 0.1 and 5% by weight, relative to the weight of the composition.

According to an advantageous embodiment, the perfumed composition according to the invention comprises , the phospholipid layer is 0.05~2% by weight, and the phospholipid layer is approximately 0.5~2% by weight. Contains about 0.05-2% by weight of fatty alcohol and direct spraying. It exhibits an antimicrobial activity of at least 90% as determined by the method.

“Perfume base with antimicrobial action” (“PBAA”) can be used alone or , solutions in conventional diluents, solvents or coingredients. or a perfume base formed from a mixture of perfume substances in suspension; Substances include, for example, esters, ethers, alcohols, aldehydes, ketones, aceta nitrogen-containing compounds or in a variety of chemical classes consisting of heterocyclic sulfur-containing compounds, as well as essential oils of natural origin. selected. The selection of these fragrance ingredients depends on the nature of the desired olfactory effect, as well as This is suggested by the required overall antimicrobial action of the aforementioned perfume base.

According to an advantageous embodiment according to the invention, the “PBAA” is applied by the direct spray method described below. exhibits an antimicrobial activity of at least 60% when measured as However, this antimicrobial The biological activity figures purely imply that other bases with low microbial activity are satisfactorily sufficient for use in perfumed compositions according to the invention. What is obvious is that it should be noted.

Therefore, it is also generally recommended to include a major amount of fragrance ingredients known to have antimicrobial properties. , advantageously can be defined as a perfume paste containing more than 60% by weight.

The perfume paces do not need to be listed in an exhaustive manner in this case. In fact, public There are numerous examples of such components in the state of the art (e.g. European Patent No. 45 No. 1889 and references cited therein), and a person skilled in the art would be aware of the current Ingredients can now be selected to harmonize the olfactory components that are present.1. The antimicrobial effect is also provided by the fragrance pace mentioned above, and the antimicrobial effect of the fragrance base. The required amount of these components with respect to the required amount of those components whose action is purely olfactory. Determined by percentage.

Furthermore, according to the present invention, the antimicrobial effect is determined by the direct spray method described below. The fragrance component, which has a small amount (both 60%), also has an antimicrobial effect in the "PBAA". It has been established that it may be advantageously used as a perfume ingredient. Therefore, the present invention is also subject to the invention and has a low antimicrobial effect when measured by direct spray method. at least 60% fragrance ingredients by weight, with respect to the weight of the base; %, and the perfumed composition containing this °PB A 'PBA characterized by being an advantageous embodiment of the invention It also has an “A”.

As mentioned above, "PBBAA" also refers to the perfumed composition according to the invention. fulfills the function of giving the desired odor note. Therefore, ``PBAA'' is also a commonly used fragrance ingredient. The effect of this fragrance component is mainly olfactory, and the above-mentioned microbicidal fragrance Like the components, they may be selected among chemical species as already mentioned above. of these ingredients The choice depends on the desired olfactory effect and the nature of the product to be perfumed, as well as Of course, it depends on the preferences of the investigator who creates it.

"PBAA" present in the perfumed composition according to the invention is such that or in microencapsulated form, or further as EP 279328 or perfume in the form of an emulsion such as those described in the specification of the same No. 384034; may be added to the composition. The information contained in these documents regarding the content or preparation of the suspension or using the methods described in the document. Regarding the micro-encapsulation of perfume pastes, in this case the citation is included.

"PBAA" is added to the perfumed composition according to the invention in conventional concentrations. Ru. These concentration numbers depend on the nature of the final deodorant or antiperspirant product. quality, as well as the odor effect required, and the expert can adjust these to this parameter. It can be selected very well as a function of the controller. Advantageous concentrations have already been mentioned above.

The flavored composition according to the invention is a flavonoid-rich plant extract. It may also contain. These are plant extracts that are soluble in water or ethanol. and no longer contain essential oils, the essential oils have been previously extracted by steam distillation. It is. The antioxidant properties of these extracts strengthen the deodorant power of the formulation. become

A wide variety of plants such as rosemary, sage, lavender and lapandine, Also extracts from thyme, green tea, oregano, coriander and laurel Can be used for this effect. olive tree leaves or fruit or eucalyptus Extracts from trees, as well as orange and lemon trees, and other Extracts from the leaves and fruit peels of foxglove trees can also be used. . Particularly favorable results have been obtained with extracts of rosemary, in which Spice Extract AR trademark Food Ingredients and 5p ecialities S, A, Vevey, 5w1tzerland)? may be cited as an example.

These plant extracts are generally in the form of aqueous or ethanolic solutions; A concentration of about 0.05 to 0.5% by weight based on the weight of the composition in which these are mixed. and is added to the composition. If the fragrance pace is, for example, EP 279328 is used in a micro-encapsulated form as described in Specification No. 384034. When used, the plant extract is incorporated into the encapsulation emulsion.

The perfumed composition according to the invention may also contain other substances, such as hydrocolloids. contains. These are natural or synthetic polymeric substances, such as carboxymethyl cellulose. water-soluble proteins, plant resins such as gum arabic, alginates and carrageenan.

Advantageously also by using polyvinylpyrrolidone or its quaternary derivatives , it was shown that the antimicrobial action of the formulation was enhanced.

The perfumed composition according to the invention avoids the use of conventional disinfectants and antiperspirants. However, if desired, these drugs can be added to this formulation. Of course it is. The concentration at which these drugs are added is then the usual concentration, i.e. Typically lower than concentrations associated with disinfectants and bacteriostatic agents.

The perfumed composition according to the invention can be used in the production of various products intended for body care. Particularly appropriate. These products themselves come in many different forms, for example soap, roll-ons, aerosols, or mechanical or It may be present as a manual pressure pavolizer. depending on the nature of these products , the composition is ultimately mixed into an aerosol propellant, e.g. in the form of an ethanol a-liquid. or even commonly used in these products and in the examples mentioned below. The described additives may be used in additives with components of various nature.

These deodorant or antiperspirant products according to the invention can be manufactured using conventional equipment. can be obtained by mixing different components. The mixing technique is known per se. , and its detailed explanation is not guaranteed here. A detailed example will be described later.

Furthermore, the perfumed compositions according to the invention are used very widely, i.e. with advantage. It has also been found that they can be used in detergents and fabric softeners. In fact, this product Fabrics treated with It was recognized that there was a need for this. Moreover, cationic phospholipids and cetyl alcohol or a combination with myristyl alcohol is seen to have a softening effect on fabrics. and therefore a fourth tension activator, e.g. used for this softening effect in conventional manner. Reduce the use of stearyldimethylammonium chloride or This made it possible to further reduce costs.

In addition, these two components, and especially phospholipids, are the fragrance of "PBAA". It has also been found that PBAA can be used as a detergent or fabric softener. When used alone to add fragrance, the scent effect on textiles is significantly stronger. It is very durable and does not come off easily, so it is extremely long-lasting.

As described by G. Holzner in the above quotation The direct spray method, or “DSM”, is a method for determining the bactericidal effect or effectiveness of cosmetic preparations used on the skin. or antimicrobial effects.

By dispensing an aerosol valve, you can dispense ready-to-use deodorant formulations or Antiperspirant formulations or solutions corresponding to the active substance are pre-infected with the desired bacteria. Sprayed directly onto the surface of the nutrient gel. Then, on the subsequent processed circular area For bacterial measurements, bacteria are incubated at 37°C for 24-48 hours. Next, add flavoring The antimicrobial action of the added composition is such that the entire circular area treated is free of microorganisms. Determined by measuring the extent of the compartment. The nutrient gel inoculated with bacteria was When processing with the composition or its active elements, the ratio of the two ranges is approximately 80% or more, the perfumed composition according to the invention is a good deodorant. It was recognized that it has an anti-inflammatory effect.

Regarding the figure, it has a 0.4mm diffuser at the outlet. A 50m1 glass aerosol flask (1) equipped with a placement valve (2) placed in a fixing device on the top of the tri-plater (4), so that the outlet of the valve is located at the top of the pan (4). It is 9 cm above the surface. Under these conditions, a circle of approximately 3 cm in diameter was formed on an agar plate. A spray cone is formed that features a surface. Vetri flat plate is pA @ It is made of plastic material or glass and has a diameter of 9 cm.

Conventional Belly gels are available on the market and already contain nutritional gels. A flat plate is used. Using a Pasteur pipette, remove (already desired bacteria or Cultures inoculated with multiple bacteria and incubated at 37°C for 48 hours! A droplet of liquid 10 Place it on an agar plate, and spread the culture solution evenly on the agar plate using a glass spatula. be dispersed. This was incubated for 2 hours at 37°C, and the plate was placed on a fixation device (3). placed.

Exemplary for determining the antimicrobial action of a flavored composition according to the invention , flavored compositions when testing aerosol products carried out as follows: and propellant in the flask (1), for example in respective proportions of 40 and 60%. is supplied within. Formulas intended for use in deodorants or antiperspirants When the composition has been treated, the active ingredients of the composition are used in proportions of 9 to 9. in 5% ethanol and into a flask with propellant as described above. It is dissolved in the resulting solution. The dosing valve is then placed at the tip of the plunging tube. It was set up in a manner known per se, taking care that the liquid reached the bottom of the flask.

Place the flask on the fixture in such a way that the mouth of the valve points towards the Petri plate. Installed. By simply activating the valve, the Vetri pan will spray out the activated A liquid. misted. The surface of the sprayed plate was therefore measured and then at 37°C for 24-48 hours. cultured for a period of time. After incubation, the area of the plate compartment immunized with the microorganism is measured and The antimicrobial action of the perfumed composition according to the invention was determined.

Blanks typically consist of 95% ethanol.

1-tion) is always sprayed on a flat plate under the same conditions to control the purpose. misted.

For this method, the following bacterial cultures were used: Staphylococcus evidel Staphyloc.

ccus epidermidis) Staphylococcus aureus s) Escherichia cali Pseudomonas a Pseudomonas aeruginosa Candida albicans Corynebacterium Corynebacterium pseudodiphtheriae iphteriae) This is the group that encompasses the organisms most commonly encountered on the skin. It is.

As mentioned above, the deodorant composition has an effective effect against the bad odor of sweat. , deodorant formulations should contain as large a spectrum of bacteria as possible and, in any case, It is well known that antimicrobial agents must have a bactericidal action that includes and counteracts the aforementioned organisms. . The composition according to the invention now effectively prevents the action of all these microorganisms. That was confirmed.

The aforementioned method also measures the antibacterial activity of a single component of a perfumed composition according to the invention. It is clear that it may be used to define With this method, flavoring is not added. A fragrance base, The aforementioned pages exhibiting a constant single antimicrobial effect when measured by the direct spray method. It is possible to obtain a flavored composition according to the present invention when the , this effect was confirmed in ethanol as a spray solution under the conditions described above. It is measured using a solution of ``PBAA''.Of course, ``PBAA'' refers to this It is present in the solution in the same proportions as in the perfumed composition according to the invention.

Perfume ingredients intended to be incorporated into perfume pastes having antimicrobial action; The antimicrobial activity of 'PBAA' may also be measured under the conditions described above, but A solution of a fragrance ingredient in ethanol is used as the W solution, and the solution in the fragrance ingredient is It is used at the same concentration as in "PBAA" above.

The invention will now be explained in detail by way of example.

Brief description of the diagram This single figure is an overall view of an apparatus using the Direct Spray Method ("DSM").

How to carry out the invention Example 1 A fragrance base with bactericidal activity was produced by mixing the following ingredients: Ingredients parts by weight Benzyl acetate 10.7 Cyclohexyl acetate ★ 5.0 Styraryl acetate ★ 1.5 Octatool★0.3 Decanol★3.0 Amylcinnamic aldehyde 4.0% Ambrox in DIPG DL　(Ambrox■D[,)...0・5 Brazilian rosewood oil ★ 10.0 Morotsuko chamomile oil ★ 2.5 Allyl caproate ★ 3,0 Delphone　★　5.0 years old range leaf anhydrous★　1.5 Geraniol★8.0 Madagascar clove oil★5.0 Bourbon geranium oil★4.0 Hedione O”★ 1O10 Hydroxycitronellal 2. 5 lralia O” 1, 5 synthetic jasmine anhydride 12.0 Wardia O” 6.0 Synthetic Iranian oil ★ 4.0 Total too.

★Fragrance ingredients exhibit over 70% antimicrobial activity (at a concentration of 0.5%, ethanol (when diluted in water), measured by direct spray method.

1) Tetramethylperhydronaphthofuran; Source: Firmenich S.A. (F irmenich SA), Geneva, Switzerland 2) Pentylcyclopentanone: Source: Filmenitz SA, Geneva, Switzerland vinegar 3) Methyl dihydrojasmonate: Source: Filmenich SA, Geneva, S. chair 4) Methylionone (mixture of isomers); Source: Firmenitz SA, Geneva; Switzerland 5) Source: Firmenitz SA, Geneva, Switzerland Etano at a concentration of 1.5% The perfume base, which is a solution in It shows an average antimicrobial activity of more than 80% when measured by the direct spray method; also summarizes the antimicrobial action of the compositions according to Examples 2.5 and 6.

+ More than 70% antimicrobial action, measured by DSM * More than 80% antimicrobial action Antimicrobial action, measured by DSM** More than 90% antimicrobial action, measured by DSM Regular schedule 2 Fragranced Compositions for Pressure Spray Mechanical or manual pressure spray systems (″ Used with a device consisting of a “Hombus Spray” or “Squeeze Bottle”) A perfumed composition with deodorizing action, intended to be used as Manufactured using Ingredients Composition 1 Composition 2 (weight%) Klucel EF (Klucel EF) l+-0, 3 water 22. '20.9 Luviquat Mono CP (Luviquat Mono CP)”-0, 2 Luviskol K-30 (Luviskol K-30)”-0,4 Gafquat HS-100 (Gafquat HS-100)”-0,2 95% ethanol 75.0 75.0 Phospholipid EFA5' 0.4 0.4 Rosemary extract soluble in ethanol 0, 2 0. 2 Myristyl alcohol 0.2 0.2 Cremophor RH40 (Chremop hor　RH40)　　0,7　0.7 Fragrance” 1.3 1.3 Tenotx GTII'+ 0. 2 0. 2 total 100.0 100. O l) Hydroxypropylcellulose, source, Hercules Co, ), USA 2) Hydroxyethyl cetyldimonium phosphate, BASF AG, Germany 3) Polyvinylpyrrolidone; Source: BASF (BASFAG), Germany 4) Polyquaternium 28. Source: GAF Inc. (GAF＾G), USA 5) Rylamideprovir PG-dimonium chloride phosphate, Source: M ONA Inc. (MONA Ind.), USA 6) Hydrogenated and ethoxylated castor oil, source BASF AG ), Germany 7) Evasion l 11, 092, Cito Lass, spicy type, antimicrobial activity over 70%: Source: Firmenitz SA (Firmenich SA), Geneva 8) Tocopherol, source: Eastman Chemicals (Eastman Ch. (chemicals), United States The above-mentioned ingredients are mixed by a method known per se and sprayed. - injected into the device. Composition 2 is described in European Patent No. 384034. It consists of the same active elements as composition I in the form of an encapsulated emulsion of the composition type.

The average antimicrobial activity of composition 1, determined by the direct spray method, is shown in Table 1. Over 90% of sea urchins.

Example 3 0-Fragranced Composition for Roll-on Use in Roll-on Type perfumed composition with antiperspirant action intended to be mixed into a device for use The product was manufactured using the following ingredients. Ingredients parts by weight Micro Dry Ultrafine ’　20.0 Dow Corning 345 (Dow Corning 345)”73.3 Absolute ethanol 1.5 Bentone 38 (Bentone 38)” 2, 7 total 100.0 1) Aluminum hydrochloride, source: Reheis C hem, Co,), USA 2) Nkero, Methicone Source: Dow Chemicals (D owCheLI+cals), USA 3) Quaternium 18-hectorite, source: Rheox I nc, ), USA 4) Lixia liquid, aldehydic, floral tie Antimicrobial activity exceeding 70%, Source: Firmenitz S.A. nich SA), Geneva The above-mentioned components were mixed by conventional techniques to obtain an effective base. The zero-order mixture prepared in advance as described below is placed in a roll-on type distribution device. Injected inside.

effective base This base was obtained as described below using the following ingredients: Ingredient weight Wednesday 115.000 Tylose H-10”1, OOO soluble in water rosemary extract 25,000 Sugar 1.000 Capsul” 49, 175 Hostaf xt K L-3 40 (Hostaphat KL-340νゝ0.200 Phospholipid EF, A” 15.000 Citric acid 1.000 Ao engineering lOX (Aloe l0X) 5'10. 000 ultrafine powder aracidoin ( Micronised, 1lantoin)”5.000 Antifoaming agent 71 0.100 Honorary fee II 25.000 8HTII 0. 025 Tenotx GTII”’ 2.500 Total 250.000 1) Hydroxyethyl cellulose, source, Hoechst AG ),Germany 2) Starch Na-octenyl succinate, source: National Starch Company (Nat ional 5tarch Inc.), USA 3) Triwaureth-4-phosph Source: Hoechst, Germany 4) See example 2 5) 7ox extract; Source: Terry Carp, USA 6) Source: Chemie Linz, Austria 7) Silicone oil hole, fiIi! , Source: Bayer +AG, Germany 8) See above 9) pt-Butylhydroquine toluene, source: Shell Co. ), Netherlands 10) Tocopherol, source Eastman Chemicals (Ea Stman Chemicals), USA This active base ingredient is The resulting milk and liquid were melted alternately at room temperature. The mixture was thoroughly homogenized using a version 2.0 version mixer.

The emulsion was then heated to 60'C and a conventional Buechi type spray was applied. Spray dry in the dryer, the inlet air temperature is 220 °C, and mix the powder. The temperature of the outlet air was 120°C. In this way, all of the aforementioned except water A powder containing the ingredients was obtained. This powder is a water-soluble microcapsule with fragrance. form cells.

The powder thus obtained is then incorporated into a perfumed composition in the proportions indicated. mixed in.

Example 4 Flavored compositions for aerosol sprays In spray type usage equipment The antiperspirant flavored composition intended to be mixed with the following ingredients: manufactured using minutes Ingredients parts by weight Micro Dry Ultrafine 8.0 Dow Corning 345 (Dow Corning 345)”19.6 Fragrance ″0.4 Effective base” 2.0 Propane/butane propellant” 70.0 Total 100.0 1), 2), 3) and 4) See Example 3 5) 2.5-bar mixture The mixture prepared in conventional manner was poured into a spray aerosol container.

Example 5 Flavored compositions for aerosol sprays used with spray-type equipment A perfumed composition with deodorant action, intended to be Ingredients manufactured by mixing parts by weight Klucel EF (Klucel EF)” 0, 30 Lexen F e 3 sp e c, (Rexene Fe35pec,)” Phospholipid PTC ”　0.30 Luviskol K 30 (Luviskol K2O" 0, 50 Gafukuo HS-100 (Gafquat 1 (S-100) 51D, L-a-t Copherol (D, La-Tocopherol) Soluble in ethanol Rosemary extract total 100.00 ■) See example 2 2) Dihydroxyethylglycerin; Source, Rexolin 3) Cocamidopropyl PG-dimonium chloride phosphate, source: Mona Company ,US 4) See example 2 5) See example 2 6) Source: Hoffmann-La Roche Switzerland 7) Spice Extract AR, Source: FTS, Pevey, Switzerland 8) Perfume base as described in Example 1 The aforementioned ingredients were mixed in such a way that a completely homogeneous mixture was obtained. This mixture Dimethyl ether was added to the mixture at a ratio of 60:40, and the mixture was dispersed into an aerosol powder. injected into the fabric device.

The average antimicrobial activity of this composition is greater than 90% when measured by direct spray method. (See Table 1).

Example 6 Flavored compositions for aerosol sprays used with spray-type equipment A perfumed composition with deodorizing action, intended to be mixed with the following ingredients: manufactured by Ingredients parts by weight 95% ethanol 96.6 Phospholipid P"rC" 0.2 Rosemary extract soluble in ethanol 1), 2), 3) and 4 ) See Example 5. The mixture was injected into a sparger with a propellant of: Relative proportions of active mixture and propellant were 65% and 35%, respectively.

The flavored compound obtained in step 2 is 90% effective against all the aforementioned organisms. It had an average antimicrobial effect exceeding .

Example 7 Flavored compositions for soaps A perfumed soap was made using the following ingredients:

Ingredients parts by weight Total 100.0 1) Prisavon 9250 (Prisavon 9250); Source: Unikema (tlnichema) 2) Perfume base according to example 1 3) See previous example The first portion was mixed and heated slightly to obtain a homogeneous emulsion. Next, part 1 and the second mouth part were mixed using a rolling mill with three rolls. lastly, The paste thus obtained is extruded in an extrusion mold and the soap is punched out. Ta.

This soap's active base ethanol solution (Part 2) contains three ingredients: When used at the indicated rate, it showed close to 100% antimicrobial efficacy.

On the other hand, the “Hill Top” type test conducted by a panel of five people , showing that the soap thus produced exhibits an average deodorant value of 2°8. did.

Example 8 Flavored compositions for liquid fabric softeners For use in liquid fabric softeners Ingredients used to produce a flavored composition intended for Department IW fee 1+2.0 ■ Phospholipid PTC" 15.0 Cetyl or myristyl alcohol 5.0■ Deionized water 77.8 (Citric acid 0.2 1) Perfume base according to Example 1 2) See previous example The first part and the mth part are separately heated to 60°C, and the mth part is injected into the opening part. Ta. Stir the mixture until the temperature reaches 40°C and add the first part, at the same time Stirring was continued until a homogeneous mixture was obtained and the temperature decreased to about 20°C.

For use, add 30-50 g of this emulsion to washing fabrics, which is done in a washing machine. added to the final rinse water of the cycle. Alternatively, incense produced as described above The loaded compositions can also be added to conventional liquid softener bases.

Fabrics treated with the aforementioned perfumed compositions can be worn on the skin. In some cases, it had a considerable deodorant effect.

Additionally, and simultaneously, the same method was applied using a fabric softener containing the same amount of milk/Liquid. process another identical fabric punch, in this case converting said fourth opening to a conventional fourth interface. Active agents such as Hoechst's Brepagen to VK (Praepa gen IVK) (stearyldimethylammonium).

Two batches of fabric were evaluated in a blind test by a panel of expert perfumers. The dullness of fabrics treated with the composition according to the invention is similar to that of compositions containing conventional ingredients. It is significantly stronger than the fabric treated with dry fabrics, and The panel confirmed that it persists for a significantly longer period of time.

Example 9 Flavored compositions for fabric softeners A composition intended for use as a clothes softener for use in clothes dryers is prepared using the following ingredients: Manufactured: Ingredients Weight Iku Honor fee 11 15.0 Phospholipid PTC2) 40.0 Cetyl alcohol 34.8 Stearic acid 20. O l) and 2) See Example 7 Mix the ingredients and heat the mixture slightly (approximately 70°C), at which temperature it will become homogeneous. A liquid mixture was obtained. Next, a piece of paper with dimensions of 25cm x 25cm A woven tissue paper was impregnated with 1.5-2 g of this mixture. Electric tumble dryer Tissue paper was added to the wet dough in the dryer. The dough dried in the presence of this tissue paper When worn on the human body, it was flexible and exhibited considerable deodorant action.

Example 10 To test the deodorant power of the perfumed composition according to the invention, 20 The composition described in Example 2 was applied using an aerosol spray to one armpit. and do not treat the other armpit at the same time, or use products containing the same fragrance. However, when processed using a blank product containing conventional deodorant ingredients, I understood. Then give each person two armpit scents after 8.12 and 24 hours. and asked them to point out which armpit smells more pleasant.

- Weeks later, repeat the same test but change the spray, e.g. Possible implications arise from research showing that different armpits may exhibit different odors. The effect of

At the end of the two-week trial, approximately 70% of the panel members were satisfied with the product according to the invention. 25% prefer the smell of armpits treated with , and the rest preferred the odor of armpits treated with the blank product. , I was able to conclude that.

Continuation of front page (72) Inventor: Holzner, Günther Switzerland 1212 Grand Lanci Chemin de Palette 15 (72) Inventor Buchli, Franz Switzerland 1226 Tone Chemin Marcelli 3

Claims (16)

[Claims] 1. In perfumed compositions, cationic phospholipids have antimicrobial action perfume paste (“PBAA”) and fatty alcohols having 10 to 22 carbon atoms. A perfumed composition characterized in that it contains alcohol. 2. At least 80% antimicrobial as measured by direct spray method (“DSM”) The composition according to claim 1, which has a biological effect. 3. Cationic phospholipids have the formula: ▲There are mathematical formulas, chemical formulas, tables, etc.▼(I) [In the formula, R is linolamide propyl or cocamidopropyl group, and x+y is 3] The composition according to claim 1 or 2, which is a composition. 4. If the fatty alcohol is myristyl alcohol or cetyl alcohol, The composition according to any one of claims 1 to 3. 5. Claims containing from 0.05 to 5% by weight of phospholipids, with respect to the weight of the composition. A composition according to box 1 or 2. 6. The claimed composition contains from 0.1 to 5% by weight of "PBAA" with respect to the weight of the composition. A composition according to scope 1 or 2. 7. Claims containing 0.02-2% by weight of fatty alcohols, with respect to the weight of the composition The composition according to scope 1 or 2. 8. With respect to the weight of the composition, about 0.05-2% by weight of phospholipids, about 0% "PBAA" ．． 5-5% by weight and about 0.05-2% by weight of fatty alcohols and directly Claims exhibiting an antimicrobial activity of at least 90% as measured by the spray method The composition according to scope 1. 9. "PBAA" has at least 60% resistance as measured by direct spray method. The composition according to claim 1, which has a microbial action. 10. “PBAA” has at least 60% resistance as measured by direct spray method. Perfume ingredients with microbial action at least 60% by weight of "PBAA" % by weight of the composition according to claim 1. 11. Claims 1 to 1 containing a plant extract rich in flavonoids The composition according to any one of up to 0. 12. Claim 1, wherein the plant extract is rosemary extract. 1. The composition according to item 1. 13. In a deodorant or antiperspirant intended for podicare, Claim 1 A deodorant containing a perfumed composition according to any one of items 1 to 12. or antiperspirant. 14. soap, stick, roll-on, aerosol, or mechanical or manual The article of claim 13 in the form of a pressurized vaporizer. 15. A perfumed composition according to any one of claims 1 to 12. Contains detergents or fabric softeners. 16. Direct spray method for fragrance compositions with antimicrobial activity (“PBAA”) Fragrance ingredients with at least 60% antimicrobial activity as measured by antimicrobial agent, characterized in that it contains at least 60% with respect to the weight of PBAA. Perfume compositions with biological effects (“PBAA”).