CN1101227C - Silicone compositions - Google Patents

Silicone compositions Download PDF

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Publication number
CN1101227C
CN1101227C CN95196934A CN95196934A CN1101227C CN 1101227 C CN1101227 C CN 1101227C CN 95196934 A CN95196934 A CN 95196934A CN 95196934 A CN95196934 A CN 95196934A CN 1101227 C CN1101227 C CN 1101227C
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oil
poly
acid
acetate
aminoalkyl
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CN1170352A (en
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I·A·休斯
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Proctor And Gambar
Procter and Gamble Co
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q13/00—Formulations or additives for perfume preparations
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/70—Fixation, conservation, or encapsulation of flavouring agents
    • A23L27/74—Fixation, conservation, or encapsulation of flavouring agents with a synthetic polymer matrix or excipient, e.g. vinylic, acrylic polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/22—Peroxides; Oxygen; Ozone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/58—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
    • A61K8/585—Organosilicon compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89—Polysiloxanes
    • A61K8/896—Polysiloxanes containing atoms other than silicon, carbon, oxygen and hydrogen, e.g. dimethicone copolyol phosphate
    • A61K8/898—Polysiloxanes containing atoms other than silicon, carbon, oxygen and hydrogen, e.g. dimethicone copolyol phosphate containing nitrogen, e.g. amodimethicone, trimethyl silyl amodimethicone or dimethicone propyl PG-betaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L9/00—Disinfection, sterilisation or deodorisation of air
    • A61L9/01—Deodorant compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A61Q11/02—Preparations for deodorising, bleaching or disinfecting dentures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/22—Gas releasing
    • A61K2800/222—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/24—Thermal properties
    • A61K2800/244—Endothermic; Cooling; Cooling sensation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Detergent Compositions (AREA)
  • Cosmetics (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Silicon Polymers (AREA)
  • Macromonomer-Based Addition Polymer (AREA)

Abstract

A flavor, perfume, cooland or antimicrobial composition comprising an aminoalkylsilicone having an aminoalkylsiloxane content of from about 0.1 %-2 % on a repeating unit basis. The composition provides improved surface residuality, impact and/or antimicrobial efficacy.

Description

Polysiloxane composition
Invention field
The present invention relates to contain polysiloxanes compositions and individual health care product for example, laundry with and various articles for daily use such as the cleaning agent of domestic, bleaching composition in purposes.Specifically, relate to the lipotropy compositions that contains polysiloxanes, they are based on flavorant, daily use chemicals spice, freshener (coolant) or antimicrobial as lipophile, to on by the surface of its processing (for example tooth, artificial tooth, skin, hair, medicated clothing, tableware, workbench surface etc.), described compositions table reveals better residual, effect and/or effectiveness.In addition, the present invention relates to contain the bleaching composition of polysiloxanes, said composition also comprises for example daily use chemicals spice, flavorant etc. to bleaching responsive composition, and shows higher stability.
Background of invention
The lipotropy compositions, for example flavorant, daily use chemicals spice, freshener and antiseptic composition are directly used or are used in the various article of everyday use widely, comprising cosmetics, the oral cavity is used and the artificial tooth compositions, bleaching, dishwashing detergent, hard-surface cleaning product and laundry cleaning product etc.A FAQs of lipotropy compositions is relevant surperficial affinity (substantivity) or the residual that improves the lipotropy composition.In a lot (if not the overwhelming majority) daily occasions, in order for example to strengthen fragrance or fragrance or to improve antimicrobial effectiveness, people need improve the remained on surface of lipophile.
For example, modern dental hygiene and artificial tooth preparation generally all contain antiplaque agent and/or anticalculus agent, and antimicrobial and flavorant.Anti-microbial effect can influence the formation of dental plaque, or this is by reducing the number of bacteria in oral cavity/tooth, perhaps is trapped in antibacterial in the film to prevent its further growth and metabolism by killing those.Flavorant weakens problem of bad breath by going the abnormal flavour effect.Some antimicrobial such as Mentholum also can be used as antozostomatic.Yet, the effectiveness of antimicrobial depend primarily on they in the oral cavity/denture in the delay situation, especially under the situation that dental plaque forms, they are in holdup time on the dental surface or the holdup time on artificial tooth.
The exemplary shortcomings of known dental formulations is, has only the short time (tooth be cleaned or the oral cavity is washed by gargling) during this period can allow the antimicrobial in the preparation play a role.This problem has increased the weight of because of the following fact, and promptly the use of dentifrice is not frequent: great majority are to use once perhaps secondary every day.Therefore, for most people, between brushing teeth, provide best dental plaque formation condition for a long time.
In many other people and daily application, people need provide the surperficial affinity of reinforcement.For example laundry detergents can obtain improvement on the quality by improving the fragrance of daily use chemicals spice in thereby the affinity of fabric face is strengthened the washing back or used.Antimicrobial affinity of strengthening is because can the elimination stink relevant with perspiration or other dirt also be very useful.The daily use chemicals spice affinity of strengthening also is very valuable in senior perfumery cosmetics.On the other hand, the freshener affinity of reinforcement is very useful in the product of treatment cough/flu.
So people need to develop a kind of lipotropy compositions that remained on surface, effect and/or the antimicrobial efficacy of improvement are arranged always.
The lipotropy compositions, for example the uses in containing the compositions of bleach such as daily use chemicals spice, flavorant also can produce many problems, especially with the bleach effect after the fragrance that causes or the characteristic or the loss of strength of fragrance.The effectiveness of bleach also can be adversely affected.So the needs raising contains stability and the effectiveness to the bleaching composition of the component of bleach sensitivity.
Knownly can in dentifrice composition, add (gathering) siloxanes (silicone), it is said to apply tooth and prevent decayed tooth and painted.For example, GB-A-689,679 disclose a kind of collutory, and it contains organopolysiloxane, adheres to tooth or removes following material from tooth to prevent following material: tar, mottle, tartar and food particle.Collutory can contain antibacterial such as thymol, and flavorant and daily use chemicals spice.
US-A-2,806,814 disclose the artificial tooth preparation, and it contains the higher aliphatic amide of amino carboxylic acid compounds simultaneously as active component and polysiloxane compound.This patent points out, proposed to prevent with polysiloxane compound that tar, mottle, tartar etc. from adhering to tooth or being convenient to and removed these materials from tooth.It is said that polysiloxane compound can be used as synergist and improves the antibacterial activity of active component and press down acid activity.It is said that dimethyl polysiloxane is effective especially.Can contain flavorant oil and/or Mentholum.
The quaternary ammonium salt that US-A-3624120 discloses cyclic polysiloxanes is used as cationic surfactant, bactericide and anti-caries agent.
So, the invention provides flavorant, daily use chemicals spice, freshener, antimicrobial or other lipotropy compositions, it has improved surperficial affinity, effect and/or effectiveness.
The present invention also provides a kind of bleach compositions, wherein comprises a kind of inorganic persalt bleach and a kind of lipotropy compositions, for example flavorant and/or daily use chemicals spice, and also it has the stability of raising.
Summary of the invention
According to a first aspect of the invention, flavorant, daily use chemicals spice, freshener, antimicrobial or other lipotropy compositions are provided, have wherein contained by the poly-aminoalkyl siloxanes (aminoalkylsilicone) of a repeated unit basis aminoalkyl content of siloxane for about 0.1-2%.
The invention still further relates to and will gather aminoalkyl siloxanes and the lipophile coupling that is selected from flavorant, daily use chemicals spice, physiological cooling agents, antimicrobial and composition thereof to improve remained on surface, wherein poly-aminoalkyl siloxanes is selected from by the poly-aminoalkyl siloxanes of a repeated unit basis aminoalkyl content of siloxane for about 0.1-2%.
In another aspect of this invention, bleaching composition is provided, it contains the inorganic persalt bleach, is selected from the lipophile of flavorant, daily use chemicals spice, physiological cooling agents, antimicrobial and composition thereof and is the poly-aminoalkyl siloxanes of about 0.1-2% by a repeated unit basis aminoalkyl content of siloxane.
The invention still further relates to the lipophile coupling that will gather aminoalkyl siloxanes and inorganic persalt bleach and be selected from flavorant, daily use chemicals spice, physiological cooling agents, antimicrobial and composition thereof to improve surperficial affinity, wherein poly-aminoalkyl siloxanes is selected from by the poly-aminoalkyl siloxanes of a repeated unit basis aminoalkyl content of siloxane for about 0.1-2%.
All herein percentage ratio and ratio all are to calculate by the weight of total composition, unless otherwise indicated.
Therefore, compositions of the present invention contains poly-aminoalkyl siloxanes antiplaque agent and the lipophile that is selected from flavorant, daily use chemicals spice, physiological cooling agents, antimicrobial and composition thereof.Other compositions of the present invention is then got the form of bleach and/or composition of detergent, wherein comprises poly-aminoalkyl siloxanes stain remover and lipophile.
Generally, poly-aminoalkyl siloxanes is selected from acyclic, hydrophobic poly-aminoalkyl siloxanes, and its formula comprises two kinds of elementary cells:
1) (R 1) m(R) nSiO (4-m-n)/2, wherein m+n is 1,2 or 3; N is 1,2 or 3; M is 0,1 or 2; With
2) (R 1) a(R 2) bSiO (4-a-b)/2, wherein a+b is 1,2 or 3; And a and b be integer,
Wherein, R 1And R 2Be selected from independently of one another: alkyl and alkenyl, hydroxyl, alkoxyl and acetoxyl group, for example R of H, about 1-10 carbon atom being replaced arbitrarily by fluorine or cyano group 1And R 2Be selected from methyl, ethyl, phenyl, vinyl, trifluoro propyl and cyano group propyl group independently of one another, and R is
Figure C9519693400071
R wherein 3Be about 1-20 the carbon atom that can at random be replaced or be interrupted by oxygen atom, the divalent alkyl of preferably about 3-5 carbon atom, R 4, R 5And R 6Can be identical or different, they are selected from: H, about 1-20 the carbon atom that can be is at random replaced or be interrupted by N and/or O atom, preferably about 1-10 carbon atom, the alkyl of more preferably about 1-4 carbon atom; And X -Be monovalent anion such as halogen ion, hydroxyl and tosylate, by a repeated unit basis, this poly-aminoalkyl siloxanes contains the 0.1-2% that has an appointment, preferably the unit of about 0.5-2% (1).
In a preferred example, poly-aminoalkyl siloxanes is XF 49B1989 (amodimethicone).XF 49B1989 is the polydimethylsiloxanepolymer polymer that contains aminoalkyl, and aminoalkyl can be positioned on the side chain or one or more end of polydimethylsiloxane chain.Preferably so poly-aminoalkyl siloxanes, wherein aminoalkyl part R is selected from: (CH 2) 3NH 2, (CH 2) 3NHCH 2CH 2NH 2, (CH 2) 3N (CH 2CH 2OH) 2, (CH 2) 3NH 3 +X -, and (CH 2) 3N (CH 3) 2(C 18H 37) +X -, especially be selected from (CH 2) 3NH 2(CH 2) 3NHCH 2CH 2NH 2Also preferred mean molecule quantity is about 5000 or higher, preferably about 5000-100,000, more preferably about 5000-30,000 poly-aminoalkyl siloxanes.
Be applicable to that poly-aminoalkyl silicone compounds of the present invention is known.For example at US-A-2, provided the method for the poly-aminoalkyl siloxanes of preparation in 930,809.
The example of XF 49B1989 comprises OSI ' s Magnasoft fluid.These polymer contain and are connected the structural aminoalkyl groups of main polydimethylsiloxane.The unitary typical structure that MagnasoftShi contains aminoalkyl is
-OSi(Me)C 3H 6NHCH 2CH 2NH 2。
The poly-general amount of aminoalkyl siloxanes is about 0.01-0.25%, preferably for about 0.1-5%, is more preferably about 0.5-1.5% (weight).
Compositions of the present invention preferably also contains lipophilic compound.Generally speaking, be applicable to that lipophilic compound herein is the material of oil sample, they are solvable in poly-aminoalkyl siloxanes, preferably dissolubility in the time of 25 ℃ at least about 1%, preferably at least about 5% (weight).Preferred lipophilic compound is selected from flavorant, daily use chemicals spice, physiological cooling agents and Antimicrobe compound.Poly-aminoalkyl siloxanes is used to improve the affinity of lipophilic compound to handle surface, thereby improves and/or keep the effect and/or the antimicrobial efficacy of flavorant, daily use chemicals spice or freshener.
Be applicable to that lipophilic flavorant of the present invention comprises that one or more are selected from following flavorant component: wintergreen oil, Herba Origani oil (oregano oil), Bay leaves oil, Oleum menthae, Oleum Menthae Rotundifoliae, Oleum Caryophylli, Sha Erweiya oil, Sassafras oil, Fructus Citri Limoniae oil, Oleum Citri tangerinae, Oleum Anisi Stellati, benzaldehyde, Semen Armeniacae Amarum oil, Camphora, cedar leaves oil, marjoram oil, citronella oil, Essential lavender oil, mustard oil, Oleum Pini, pinke needle oil, oil of rosemary, thyme oil, Cortex Cinnamomi leaf oil, and their mixture.
Comprise one or more known daily use chemicals flavor compositions at this lipotropy daily use chemicals spice that is suitable for, comprise essential oil, absolute oil, natural products such as resin, with synthetic daily use chemicals spice components such as hydrocarbon, alcohol, aldehyde, ketone, ether, acid, ester, acetal, ketal, nitriles, comprise saturated and undersaturated chemical compound, aliphatic, carboxylic acid and heterocyclic compound.Example at this daily use chemicals spice that is suitable for comprises geranyl acetate, linalyl acetate, geraniol acetate, acetic acid dihydromyrcene ester, tirpinyl acetate, Tricyclodecenyl acetate, Cyclaprop, acetic acid 2-phenyl chlorocarbonate, benzyl acetate, benzyl salicylate, benzyl benzoate, methyl phenyl carbinyl acetate, amyl salicylate, the dihydro (-)-methyl cis-2-pent-2'-enyl-3-oxocyclopentylacetate, phenoxyethyl isobutanoate, neryl acetate, acetic acid trichloromethyl-phenyl methyl ester, vertenex, isononyl acetate, Cedryl acetate., the cautious luxuriant ester of acetic acid Wei, benzyl alcohol, the 2-phenylethanol, linalool, tetrahydrolialool, citronellol, dimethyl benzyl carbinol, dihydromyrcenol, 2,6-Dimethyl-2-octanol, terpinol, acetaminol, geraniol, the cautious luxuriant alcohol of Wei, different camphyl-the Hexalin of 3-, 2-methyl-3-(to tert-butyl-phenyl)-propanol, 2-methyl-3-(p-isopropyl phenyl)-propanol, 3-(to tert-butyl-phenyl)-propanol, nerol, α-n-pentyl cinnamic aldehyde, jasmonal H, 4-(4-hydroxy-4-methyl amyl group)-3-cyclohexene formaldehyde, 4-(4-methyl-3-pentenyl)-3-cyclohexene formaldehyde, 4-acetyl oxygen-3-amyl group-Pentamethylene oxide., 2-n-heptyl-Ketocyclopentane, 3-methyl-2-amyl group-Ketocyclopentane, n-capric aldehyde, n-dodecane aldehyde, hydroxycitronellal, the hyacinthin dimethyl acetal, the hyacinthin diethyl acetal, geranonitrile, 3,7-Dimethyl-6-octenenitrile, Cupressus funebris Endl. ylmethyl ether, the different ketone that comes into leaves, the anisaldehyde nitrile, anisaldehyde, heliotropine, coumarin, vanillin, the oxidation diphenyl, ionone, irone, different irone, irone, cis-3-hexanol and ester thereof, 1,2-dihydroindene Moschus, 1,2,3, the 4-tetralin musk, isochroman Moschus (isochroman musk), macrocyclic ketone, the macrolide Moschus, the tridecandioic acid vinyl acetate, the aromatic nitro Moschus, and composition thereof.
Be applicable to that lipotropy antimicrobial of the present invention comprises: thymol, Mentholum, triclosan (triclosan), 4-hexyl resorcin, phenol, cineole, benzoic acid, benzoyl peroxide, Butyl Chemosept (butyl paraben), nipagin, propyl parabene, salicylamide, and their mixture.
Be applicable to that lipotropy physiological cooling agents of the present invention comprises: carboxylic acid amides (carboxamide), terpane ester and terpane ether, and their mixture.
Be applicable to that terpane ether herein is selected from the kind with following formula:
Wherein, R 5Be can at random be replaced by hydroxyl, contain within 25 carbon atoms the aliphatic group within 5 carbon atoms preferably, and X is hydrogen or hydroxyl.Such as those kinds that can buy with trade name Takasago from Takasago InternationalCorporation.A kind of particularly preferred freshener that is used for the present composition is a Takasago 10[3-1-Herba Menthae oxygen the third-1,2-glycol (MPD)].MPD is single glycerol derivatives of 1-menthol, and it has excellent refrigerant property.
The most useful carboxylic acid amides of finding is at US-A-4,136,163 (on January 23rd, 1979, authorizing people such as Wason) and US-A-4, the kind described in 230,688 (on October 28th, 1980, the authorizing people such as Rawsell).
The concentration of lipophilic compound is generally about 0.01-10% in the present composition, preferably is to be more preferably about 0.1-3% (weight) by about 0.05-5%.
The present composition can randomly comprise one or more surfactants, and this is good extraordinarily in the lipotropy compositions of the present invention that is used for solubilising lipophile and raising effectiveness.Suitable surfactant comprises non-soap anionic, nonionic, cation, amphion and both sexes synthetic organic detergent.At Gieske etc., 27 days US-A-4 of JIUYUE in 1977 has described many these suitable class reagent in 051,234.
Comprise every mole of usefulness about 0.5 C at this surfactant example that is suitable for to about 20 moles of ethylene oxide ethoxylations 6-C 18Alkyl sulfate and alkyl ether sulfate; Anionic sulphonate comprises C 5-C 20Linear alkyl benzene sulfonate salt, alkyl sulfonic ester salt, C 6-C 22Uncle or secondary alkyl sulfonate, C 6-C 24Alkene sulfonate, the sulfonation polycarboxylic acid, alkyl glycerol sulfonate, the fatty acyl glycerol sulfonate, and composition thereof; The carboxylate anion comprises C 6To C 18The primary, secondary alkyl carboxylate, ethoxy carboxylate and polyethoxy polycarboxylate surfactant, its average degree of ethoxylation is about 0 to about 10; C 5To C 17Sarcosinate, Hamposyl C sodium for example, sodium lauryl sarcosinate (Hamposyl-95 ex W.R.Grace); The condensation product of oxirane or expoxy propane and fatty acid, aliphatic alcohol, fatty acid amide, polyhydric alcohol (Arlacel-60 for example, sorbitan oleate), with the condensation product (for example Tergitol) of alkylphenol and with the condensation product (for example Pluronics) of poly(propylene oxide) and polyoxy butylene; US-A-4, the alkyl polysaccharide that discloses in 565,647; Amine oxide, cacodyl oxide base coconut amine (dimethyl cocamine oxide) for example, cacodyl oxide base lauryl amine and oxidation Cortex cocois radicis alkyl dimethyl amine (cocoalkyldimethyl amine oxide) are (Aromox); Spheron MD 30/70, for example polysorbate40 and Tween 80 (Hercules); Sorbitan monostearate, Arlacel-80 etc.; Cationic surfactant, for example cetylpyridinium chloride, cetrimonium bromide, chlorination diisobutyl phenoxy group ethoxyethyl group-dimethyl benzyl ammonium and nitric acid Cortex cocois radicis alkyl trimethyl ammonium.
Consider the solubilising of lipophile, good especially at this is non-ionic surface active agent.Have following general structure at this a kind of non-ionic surface active agent that is suitable for:
R wherein 1Be to have 8 to 22, with the alkyl or alkenyl phenyl group of 10 to 20 carbon atoms of being advisable, m and n represent 0-80 and 2-80 respectively.Usually avoid short-chain alkyl, this is for the consideration to rendeing a service, and because unreacted aliphatic alcohol can cause abnormal flavour in this class surfactant, causes scytitis sometimes.Be appreciated that the mixture that this class surfactant normally has different ethoxylated/propoxylated degree, so m and n represent propoxylation group and ethoxylation group number respectively.Ionic surfactant pack with above-mentioned general type is drawn together the product of mixed alkoxylated, and m wherein and n are between about 2 to 80, and it is about 2 to about 20, about 3 to about 10 better that m is preferably, and it is about 2 to about 60, about 5 to about 50 better that n is preferably.One of this class material is PPG-5-ceteth-20 (Croda Inc provides, and commodity are called Procetyl AWS), and m wherein and n are respectively 5 and 20.Other suitable ionic surfactant pack is drawn together the polyethoxylated surfactant, and ethoxylated alkyl phenols ether for example especially has the octyl group of 8-16EO-and nonyl 2, 2-Oxydiphenol; The C of ethoxylated fat family 8-C 20Alcohol, they can be line style or side chain, have 8 to 16, are good EO with 9 to 15; And ethoxylated hydrogenated castor oil.
Usually, the ratio of surfactant and daily use chemicals spice, freshener or other oily matter was at about 50: 1 to 1: 10, and about 20: 1 to 1: 2 better, and about 10: 1 to 1: 1 better.
Bleaching composition of the present invention also comprises one or more bleachs, can be randomly and couplings such as organic peroxy acid precursors, effervescent, chelating agen.
Bleach is the inorganic peracid salt form, and can be selected from the known bleach of knowing that is used in daily bleaching, decontamination, the denture cleanser etc. arbitrarily, for example persulfuric acid alkali metal and ammonium salt, one hydration and four hydration perborate, percarbonate (can be as GB-A-1, apply described in 466,799) and perphosphate, and the peroxide of alkali metal and alkaline-earth metal.Suitable bleach example comprises potassium, ammonium, sodium and lithium salts and a hydration and the four hydration perborate of persulfuric acid, tetrasodium pyrophosphate peroxyhydrate, and the peroxide of magnesium, calcium, strontium, zinc.But, at this wherein persulfuric acid, perboric acid and percarbonic acid alkali metal salt, especially perboric acid and percarbonic acid alkali metal salt preferably.
It is about 5% to 70% that bleach content in bleaching composition of the present invention is generally, and about 10% to 50% is better.
Can also comprise effervescent in the bleach, it is the solid matter form in example preferably, can accompany by effervescent in water and emits carbon dioxide or oxygen.Effervescent can be selected from operational foaming agent under acid, neutrality or alkaline pH condition, but be preferably by under acidity or neutral pH effectively the most effective foaming agent with under alkaline pH effectively or the most effective foaming agent mix.Effectively effervescent comprises at least a alkali carbonate or bicarbonate (sodium bicarbonate for example under acidity or neutral pH, sodium carbonate, sodium sesquicarbonate, potassium carbonate, potassium bicarbonate or their mixture) with at least a nontoxic, (the tartaric acid for example of appropriate organic on the physiology, fumaric acid, citric acid, malic acid, maleic acid, gluconic acid, succinic acid, salicylic acid, adipic acid or sulfamic acid, fumaric acid sodium, sodium acid phosphate or potassium, betaine HCL, or their mixture) mixture of Zu Chenging.Wherein, malic acid preferably.Effectively effervescent comprises persalt under alkaline pH, the alkali metal of for example aforementioned peroxidating boric acid, perboric acid and alkali salt, persulfate, percarbonate, perphosphate, and their mixture, the mixture of certain alkali-metal perborate (anhydrous, a hydration or four hydrations) and single persulfate for example, for example Caroat that sells of E I du Point de Nemours Co. , this is a kind of 2: 1: 1 mixture of single persulfate, potassium sulfate and potassium acid sulfate, its active oxygen content is about 4.5%.
Be used for the bleaching composition preferably of denture cleanser, solid matter comprises that a kind of carbonic acid (hydrogen) salt/sour effervescent is right, randomly with perborate/persulfate oxygen effervescent coupling.The coupling of two kinds of effervescents is beneficial to reaching the dissolubility and the pH condition of the required the best of best cleaning and antibacterial activity.It is about 5% to 65% that carbonic acid (hydrogen) salt component accounts in total composition usually, is preferably 25% to 55%; It is about 5% to 50%, about 10% to about 30% better that acid constituents accounts in total composition usually.
The present invention can also replenish in bleach with other component in known this class preparation.A kind of good especially other component is the organic peroxy acid precursors, can generally it be defined as peracid later and form the chemical compound that titer in the test is at least 1.5ml 0.1N sodium thiosulfate.
Following substance dissolves in the 1000ml distilled water, is prepared testing liquid:
Tetrasodium pyrophosphate (Na 4PO 2O 7·10H 2O) 2.5g
Dexol (NaBO 2·H 2O 2·3H 2O), has 10.4% dissolved oxygen 0.615g
Dodecylbenzene sodium sulfonate 0.5g
In the time of 60 ℃, in this solution, add a certain amount of activator, dosage is to add the normal activator of a part for each obtainable oxygen atom.
Vigorous stirring adds the mixture behind the activator, and it is maintained 60 ℃.Added back 5 minutes, and got 100ml solution, be pipetted into immediately on the mixture of 250g trash ice and 15ml glacial acetic acid.Adding potassium iodide (0.4g) then, is indicator immediately with starch, and the iodine with the titration of 0.1N sodium thiosulfate discharges takes off for the first time up to blueness.The milliliter number of used sodium thiosulfate is exactly the titer of bleach-activating.
The organic peracid precursor normally has one or more chemical compounds that is easy to the carboxyl groups of hydrolysis.Activator is the chemical compound of N-acyl group or O-acyl group class preferably, wherein comprises a R-CO group, and R wherein is hydrocarbon or the substituted hydrocarbon radical group with 1 to 20 carbon atom.Suitable peracid precursors example comprises:
1) structural formula is RCONR 1R 2The acyl group organic amine, RCO wherein is the carboxylic acyl group, R 1Be acyl group, R 2Be an organic group, as US-A-3, described in 117,148.This type of examples for compounds comprises:
A) N, diacetanilide N, and N-acetyl phthalimide;
B) N-acyl group hydantoin, N for example, N-diacetyl-5,5-dimethyl hydantoin;
C) Alkylenediamine of many acyl groupizations, N for example, N, N ', N '-tetra acetyl ethylene diamine (TAED) and its corresponding hexamethylenediamine (TAHD) derivant, as GB-A-907,356, GB-A-907 is disclosed in 357 and GB-A-907,358;
D) glycoluril of acyl groupization, for example tetra-acetylated glycoluril, as GB-A-1,246,338, GB-A-1 is disclosed in 246,339 and GB-A-1,247,429.
2) the amine sulphonyl of acyl groupization, for example N-methyl-N-benzoyl-Methanesulfomide and N-phenyl-N-acetyl group-Methanesulfomide as GB-A-3, are disclosed in 183,266.
3) GB-A-836,988, GB-A-963, the carboxylate that is disclosed in 135 and GB-A-1,147,871.This type of examples for compounds comprises phenylacetate, acetoxyl group benzene sulfonic acid sodium salt, acetic acid trichloro ethyl ester, sorbitol hexaacetate, fructose pentaacetate, paranitrobenzaldehyde diacetate esters, methylvinyl acetate, acetyl group acetohrdroxamic acid and acetylsalicylic acid.Other example is the ester that phenol or fortified phenol and α chloro lower aliphatic carboxylic acid form, the ester of chloracetyl phenol and chloracetyl salicylic acid and so on for example, and as US-A-3,130,165 is described.
4) general formula is the carboxylate of AcL, and Ac wherein is the acyl moiety of organic carboxyl acid, and this organic carboxyl acid at random has a C 6-C 20Alkyl or alkenyl part or a C of replacement, straight or branched 6-C 20The aryl that alkyl replaces, L is a leaving group, the pKa of its conjugate acid between 4 to 13, for example phenolsulfonic acid ester or hydroxy benzoate.Better person in this compounds:
A) Ac is R 3-CO, R 3Be the straight or branched alkyl, have 6 to 20 carbon atoms, 6 to 12 is good, and 7 to 9 are better, wherein begin and the longest straight chained alkyl that it is included comprised 5 to 18 carbon atoms from carbonyl carbon, with 5 to 10 be good, R 3Can be randomly by Cl, Br, OCH 3Or OC 2H 5Replace (being preferably in the α position of carbonyl carbon).The example of this type of material comprises 3,5,5-trimethyl acetyl oxygen base benzene sulfonic acid sodium salt, 3,5,5-trimethyl acetyl p-methoxybenzoic acid sodium, 2-ethyl hexanoyl oxygen base benzene sulfonic acid sodium salt, the ninth of the ten Heavenly Stems acyloxy benzene sulfonic acid sodium salt and hot acyloxy benzene sulfonic acid sodium salt, acyloxy wherein is para-orientation preferably;
B) general formula of Ac is R 3(AO) mXA, wherein R 3Be a straight or branched alkyl or alkylaryl, have 6 to 20 carbon atoms at its moieties, with 6 to 15 be good, R 5Can be at random by Cl, Br, OCH 3Or OC 2H 5Replace, AO is oxyethylene group or oxypropylene group, and m is 0 to 100, and X is O, NR 4Or CO-NR 4, and A is CO, CO-CO, R 6-CO, CO-R 6-CO, or CO-NR 4-R 6-CO, R wherein 4Be C 1-C 4Alkyl, R 6Be alkylidene, alkenylene, arlydene or alkylidene aryl, its alkylidene or alkenylene partly have 1 to 8 carbon atom.This type of bleach-activating comprises that structural formula is R 3(AO) mThe carbonic acid derivative of OCOL, structural formula are R 3OCO (CH 2) 2The succinic acid derivative of COL, structural formula are R 3OCH 2The glycolic derivant of COL, structural formula are R 3OCH 2CH 2The hydoxy-propionic acid derivative of COL, structural formula are R 3The oxalic acid derivant of OCOCOL, structural formula are R 3The maleic acid of OCOCH=CHCOL and fumaric acid derivatives, structural formula are R 3CONR 1(CH 2) 6The acyl amino caproic acid derivant of COL, structural formula is R 3CONR 1CH 2The acylglycine derivatives of COL and structural formula are R 3N (R 1) CO (CH 2) 4The amino of COL-6-carbonyl caproic acid derivant.Wherein, m is good with 0 to 10, and m is 0 o'clock R 3C preferably 6-C 12Alkyl, C 6-C 10Better, m is not 0 o'clock R 3C preferably 9-C 15Alkyl.The definition of leaving group L as above.
5) acyl group cyanurate, for example triacetyl or tri-benzoyl cyanurate, for example United States Patent (USP) 3,332, described in 882.
6) benzoyl oxide or the phthalic anhydride that replaces arbitrarily, benzoyl oxide for example, m-chlorobenzoic acid acid anhydride and phthalic anhydride.
7) the N-acetyl group precursor compound of the described lactams of GB-A-855735; especially caprolactam and valerolactam class; benzoyl valerolactam for example; benzoyl caprolactam and their substituted benzoyl analog, for example chlorine, amino, alkyl, aryl and alkoxyl derivatives.
In all above-claimed cpds, organic peracid precursor 1 (c) preferably, 4 (a) and 7.
If exist, peroxyacid bleach precursor accounts for the about 0.1% to 10%, 0.5% to 5% better of compositions gross weight, and adds with the form of bleach precursor condensation product usually.
Usually contain about by weight 5% to about 40% binding agent or flocculating agent at this preferred bleach condensation product, about 10% to 30% is better.Suitable flocculating agent comprises poly-acetyl-pyrrolidine ketone, and molecular weight is 20,000 to 500; 000 polyoxyethylene, the Polyethylene Glycol of molecular weight 1000 to 50,000; the Carbowax of molecular weight 4000 to 20,000, non-ionic surface active agent; fatty acid, sodium carboxymethyl cellulose, gelatin; aliphatic alcohol, phosphate, polyphosphate; clay, aluminosilicate and poly-multi-carboxylate.Wherein, preferred especially Polyethylene Glycol, especially molecular weight about 1,000 to about 30,000,2000 to about 10,000 is better.
Consider from dissolubility and pH characteristic, preferred bleach precursor condensation product has about by weight 10% to about 75%, be preferably about 20% to about 60% peroxyacid bleach precursor, about 5% to 60%, about 5% to about 50% is good, is more preferably about 10% to about 40% carbonic acid (hydrogen) salt/sour effervescent is right, and about 0% to about 20% peroxide borate, with 5% to about 40%, be preferably about 10% to about 30% flocculating agent.Final bleach precursor grain should have that the average grain of about 500 to 1500 μ m is direct, and about 500 to 1,000 μ m are better, and this dissolubility and product appearance to the best is very important.And, bleach precursor condensation product content be the compositions gross weight about 1% to about 20%, about 5% to 15% is better.
Its form of bleaching composition of the present invention can be mastic, tablet, granular or pulverous.The compositions of tablet form can be the single or multiple lift tablet.
Can also replenish in the bleaching composition of the present invention with the component commonly used in other this class preparation, especially previously described surfactant, chelating agen, enzyme, dyestuff, sweeting agent, tablet binder and filler, foam in hibitors (for example dimethyl polysiloxane), the foam stabiliser of sucrose fatty acid ester and so on, antiseptic, for example lubricant of fine powder of Pulvis Talci, magnesium stearate, amorphous silica fume and so on.
Comprise polyvinylpyrrolidone, molecular weight 20,000 to 500 at this tablet binder and filler that is suitable for, 000 polyoxyethylene, the Polyethylene Glycol of molecular weight about 1000 to about 50,000, about 4000 to 20,000 the Carbowax of molecular weight, non-ionic surface active agent, fatty acid, sodium carboxymethyl cellulose, gelatin, aliphatic alcohol, clay, polycarboxylate polymer, sodium carbonate, calcium carbonate, calcium hydroxide, magnesium oxide, basic magnesium carbonate, sodium sulfate, protein, cellulose ether, cellulose esters, polyvinyl alcohol, alginate esters, the plant fat with pseudocolloid characteristic.Wherein, good especially is Polyethylene Glycol, molecular weight about 1,000 to about 30,000 especially, and about 12,000 to about 30,000 is better.
Chelating agen is by being retained in the stability of helping clean and strengthen bleach in the solution with metal ions such as calcium, magnesium and heavy metal cations.The example of suitable chelating agen comprises sodium tripolyphosphate, sodium acid phosphate, tetrasodium pyrophosphate, for example nitrilotriacetic acid(NTA) and ethylenediaminetetraacetic acid and salt thereof, ethylenediamine N, the aminopolycanboxylic acid of N '-disuccinic acid (EDDS) and salt thereof and so on, for example polyphosphonic acid salt of hydroxyl ethane di 2 ethylhexyl phosphonic acid, ethylenediamine tetramethylene phosphonic acid, diethylenetriamine pentamethylenophosphonic acid and salt thereof and so on and aminopolyphosphonic acid salt.The selection of chelating agen is very unimportant, but must can be compatible with other composition in the denture cleanser under drying and aqueous solution state.Be preferably, chelating agen accounts for the 0.1% to 60%, 0.5% to 30% better of compositions gross weight.But the phosphonic acids chelating agen should account for the about 0.1% to 1%, 0.1% to 0.5% better of compositions gross weight.
Example at this enzyme that is suitable for comprises protease, alkaline enzyme (alkalase), amylase, fungus and antibacterial lipolytic enzyme, glucanase (dextranase), mutase (mutanase), glucanase (glucanase), esterase, cellulase, pectase, Lactose enzyme and peroxidase etc.US-A-3 has discussed suitable enzyme in 519,570 and US-A-3,533,139.
Following examples have further described and have illustrated the preferred implementation in the scope of the invention.
Example I is to V
Following is the representational false-tooth cleaning plate agent of the present invention.Percentage ratio calculates by the weight of total tablet.Tablet be by in drift and punch die tablet machine in about 10 5Punching press graininess mixture of ingredients is made under the pressure of kPa.
I II III IV V
Malic acid 12 10 15 - 14
Citric acid - 10 - 15 -
Sodium carbonate 10 8 10 6 10
Sulfamic acid 5 - - 3 3
PEG 20,000 - 3 7 8 5
PVP 40,000 6 3 - - -
Sodium bicarbonate 23 24 25 23 24
The Dexol monohydrate 15 12 16 30 15
Permonosulphuric acid potassium 15 18 13 - 14
Fumed silica - 3 1 1 -
Pulvis Talci 2 - - - -
EDTA - - 1 - 3
EDTMP 1 1 - - 1 -
Flavorant 5 2 1 2 1 2
The Magnasoft fluid 4 1 1.5 0.5 2 1
The bleach precursor agglomerate 9 8 10 12 10
The bleach precursor agglomerate I II III IV V
TAED 2 2 - 4 5 2.5
TMHOS 3 2 3 - - -
Sulfamic acid 2 2 2 2 3.5
Sodium bicarbonate 0.5 0.2 0.2 0.5 2
PEG 6000 2.5 2 2.4 2.5 1.5
Dyestuff - 0.8 1.4 2 0.5
1. ethylenediamine tetramethylene phosphonic acid
2. tetra acetyl ethylene diamine
3. 3,5,5-trimethyl acetyl oxygen base benzene sulfonic acid sodium salt
4.Magnasoft fluid-provide by OSI
5. pennyroyal flavorant
In the above embodiments I to V, the gross weight of tablet is 3 grams; 25 millimeters of diameters.
Example I to the false-tooth cleaning plate agent of V demonstrates better antiplaque, cleaning power and antibiotic property, and excellent tack and other physical properties and serviceability.
Example VI is to IX
Below be representational daily use chemicals spice, flavorant, freshener and antimicrobial compositions among the present invention.Percentage ratio is by total restatement of compositions.
VI VII VIII IX
PPG-5-ceteth-20 3.0 3.0 4.5 3.0
The PEG-40 castor oil hydrogenated - 1.8 4.5 3.0
Trideceth-12 2.0 - - -
Trideceth-9 - 2.0 - 3.0
Flavorant 5 2.0 3.0
Daily use chemicals spice 6 - 3.0 - -
The trimethyl butyramide 0.3 0.5 - -
Triclosan - - 1.0 0.5
The Magnasoft fluid 4 1.0 1.5 5.0 1.0
Water Complement to 100%
6. daily use chemicals spice is the complex mixture that is mainly used in each composition of odor effect.
Example VI is to the daily use chemicals spice of IX, and flavorant, freshener and/or antimicrobial compositions show surperficial affinity, effect and/or the effectiveness of improvement.

Claims (9)

1. lipotropy compositions that can be used as flavorant, daily use chemicals spice, freshener, antimicrobial or denture cleanser, it is characterized in that, the poly-aminoalkyl siloxanes that it contains by a repeated unit basis aminoalkyl content of siloxane is 0.1-2%, and described poly-aminoalkyl siloxanes is acyclic, hydrophobic poly-aminoalkyl siloxanes, and its formula comprises two kinds of elementary cells:
1) (R 1) m(R) nSiO (4-m-n)/2, wherein m+n is 1,2 or 3; N is 1,2 or 3; M is 0,1 or 2; With
2) (R 1) a(R 2) bSiO (4-a-b)/2, wherein a+b is 1,2 or 3; And a and b be integer,
Wherein, R 1And R 2Be selected from independently of one another: alkyl and alkenyl, hydroxyl, alkoxyl and the acetoxyl group of H, 1-10 the carbon atom that can be replaced arbitrarily by fluorine or cyano group, and R is
Figure C9519693400021
R wherein 3Be the divalent alkyl of 1-20 the carbon atom that can at random be replaced or be interrupted by oxygen atom, R 4, R 5And R 6Can be identical or different, they are selected from: the alkyl of H, 1-20 carbon atom can be at random being replaced or be interrupted by N and/or O atom; And X -Be monovalent anion, by a repeated unit basis, this poly-aminoalkyl siloxanes contains 0.1-2% unit (1).
2. compositions as claimed in claim 1 is characterized in that the molecular weight of this poly-aminoalkyl siloxanes is at least 5,000.
3. compositions as claimed in claim 2 is characterized in that, the molecular weight of this poly-aminoalkyl siloxanes is 5000-100,000.
4. as claim 1,2 or 3 described compositionss, it is characterized in that it contains the poly-aminoalkyl siloxanes of 0.01-25% (weight).
5. compositions as claimed in claim 1, it is characterized in that, use as flavorant, it comprises one or more and is selected from following flavorant component: wintergreen oil, Herba Origani oil, Bay leaves oil, Oleum menthae, Oleum Menthae Rotundifoliae, Oleum Caryophylli, Sha Erweiya oil, Sassafras oil, Fructus Citri Limoniae oil, Oleum Citri tangerinae, Oleum Anisi Stellati, benzaldehyde, Semen Armeniacae Amarum oil, Camphora, cedar leaves oil, marjoram oil, citronella oil, Essential lavender oil, mustard oil, Oleum Pini, pinke needle oil, oil of rosemary, thyme oil, Cortex Cinnamomi leaf oil, and their mixture.
6. compositions according to claim 1, it is characterized in that, as the daily use chemicals fragrance applications, it comprises one or more daily use chemicals spice components that is selected from down group: geranyl acetate, linalyl acetate, geraniol acetate, acetic acid dihydromyrcene ester, tirpinyl acetate, Tricyclodecenyl acetate, Cyclaprop, acetic acid 2-phenyl chlorocarbonate, benzyl acetate, benzyl salicylate, benzyl benzoate, methyl phenyl carbinyl acetate, amyl salicylate, the dihydro (-)-methyl cis-2-pent-2'-enyl-3-oxocyclopentylacetate, phenoxyethyl isobutanoate, neryl acetate, acetic acid trichloromethyl-phenyl methyl ester, vertenex, isononyl acetate, Cedryl acetate., the cautious luxuriant ester of acetic acid Wei, benzyl alcohol, the 2-phenylethanol, linalool, tetrahydrolialool, citronellol, dimethyl benzyl carbinol, dihydromyrcenol, 2,6-Dimethyl-2-octanol, terpinol, acetaminol, geraniol, the cautious luxuriant alcohol of Wei, different camphyl-the Hexalin of 3-, 2-methyl-3-(to tert-butyl-phenyl)-propanol, 2-methyl-3-(p-isopropyl phenyl)-propanol, 3-(to tert-butyl-phenyl)-propanol, nerol, α-n-pentyl cinnamic aldehyde, jasmonal H, 4-(4-hydroxy-4-methyl amyl group)-3-cyclohexene formaldehyde, 4-(4-methyl-3-pentenyl)-3-cyclohexene formaldehyde, 4-acetyl oxygen-3-amyl group-Pentamethylene oxide., 2-n-heptyl-Ketocyclopentane, 3-methyl-2-amyl group-Ketocyclopentane, n-capric aldehyde, n-dodecane aldehyde, hydroxycitronellal, the hyacinthin dimethyl acetal, the hyacinthin diethyl acetal, geranonitrile, 3,7-Dimethyl-6-octenenitrile, Cupressus funebris Endl. ylmethyl ether, the different ketone that comes into leaves, the anisaldehyde nitrile, anisaldehyde, heliotropine, coumarin, vanillin, the oxidation diphenyl, ionone, irone, different irone, irone, cis-3-hexanol and ester thereof, 1,2-dihydroindene Moschus, 1,2,3, the 4-tetralin musk, the isochroman Moschus, macrocyclic ketone, the macrolide Moschus, the tridecandioic acid vinyl acetate, the aromatic nitro Moschus, and composition thereof.
7. as claim 1,2 or 3 described compositionss, it is characterized in that it contains the poly-aminoalkyl siloxanes of 0.1-5% (weight).
8. compositions according to claim 1 is characterized in that, as denture cleanser, it comprises the bleach of inorganic peroxy acid salt form.
9. poly-aminoalkyl siloxanes can be used as flavorant in preparation, daily use chemicals spice, freshener, antimicrobial, or the purposes in the lipotropy compositions of denture cleanser, it is characterized in that, it be selected from flavorant, daily use chemicals spice, physiological cooling agents, the lipophile of antimicrobial uses together, so that better remained on surface to be provided, the poly-aminoalkyl siloxanes that wherein poly-aminoalkyl siloxanes is is 0.1-2% by a repeated unit basis aminoalkyl content of siloxane, and described poly-aminoalkyl siloxanes is acyclic, hydrophobic poly-aminoalkyl siloxanes, its formula comprises two kinds of elementary cells:
1) (R 1) m(R) nSiO (4-m-n)/2, wherein m+n is 1,2 or 3; N is 1,2 or 3; M is 0,1 or 2; With
2) (R 1) a(R 2) bSiO (4-a-b)/2, wherein a+b is 1,2 or 3; And a and b be integer,
Wherein, R 1And R 2Be selected from independently of one another: alkyl and alkenyl, hydroxyl, alkoxyl and the acetoxyl group of H, 1-10 the carbon atom that can be replaced arbitrarily by fluorine or cyano group, and R is R wherein 3Be the divalent alkyl of 1-20 the carbon atom that can at random be replaced or be interrupted by oxygen atom, R 4, R 5And R 6Can be identical or different, they are selected from: the alkyl of H, 1-20 carbon atom can be at random being replaced or be interrupted by N and/or O atom; And X -Be monovalent anion, by a repeated unit basis, this poly-aminoalkyl siloxanes contains 0.1-2% unit (1).
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