RU95110319A - METHOD OF OBTAINING PROBIOTIC PREPARATION - Google Patents

METHOD OF OBTAINING PROBIOTIC PREPARATION

Info

Publication number
RU95110319A
RU95110319A RU95110319/13A RU95110319A RU95110319A RU 95110319 A RU95110319 A RU 95110319A RU 95110319/13 A RU95110319/13 A RU 95110319/13A RU 95110319 A RU95110319 A RU 95110319A RU 95110319 A RU95110319 A RU 95110319A
Authority
RU
Russia
Prior art keywords
probiotic preparation
suspension
granules
solution
obtaining probiotic
Prior art date
Application number
RU95110319/13A
Other languages
Russian (ru)
Other versions
RU2058681C1 (en
Inventor
В.М. Батагагин
С.М. Кузина
М.Н. Мартовецкий
Н.Б. Голуб
Original Assignee
Акционерное общество открытого типа "Фармацевтическая фирма "КОНПО"
Filing date
Publication date
Application filed by Акционерное общество открытого типа "Фармацевтическая фирма "КОНПО" filed Critical Акционерное общество открытого типа "Фармацевтическая фирма "КОНПО"
Priority to RU95110319/13A priority Critical patent/RU2058681C1/en
Priority claimed from RU95110319/13A external-priority patent/RU2058681C1/en
Publication of RU95110319A publication Critical patent/RU95110319A/en
Application granted granted Critical
Publication of RU2058681C1 publication Critical patent/RU2058681C1/en

Links

Claims (1)

Изобретение относится к области медицинской микробиологии и может быть использовано в медицине. Изобретение позволяет получить сухой дозированной формы пробиотик, удобный для потребителя, устойчивый к негативному воздействию кислой среды желудка и легко распадаемый в условиях деятельности кишечника, путем введения полианионов, например соли альгиновой кислоты, в суспензию микроорганизмов и формирования гранул при контакте капель суспензии с отверждающим раствором, например с раствором хлористого кальция. Гранулы промывают водой и подвергают лиофильной сушке.The invention relates to the field of medical Microbiology and can be used in medicine. The invention allows to obtain a dry dosage form of a probiotic, convenient for the consumer, resistant to the negative effects of the acidic environment of the stomach and easily disintegrated under the conditions of intestinal activity, by introducing polyanions, such as alginic acid salt, into a suspension of microorganisms and forming granules upon contact of the suspension droplets with a curing solution for example with a solution of calcium chloride. The granules are washed with water and freeze dried.
RU95110319/13A 1995-06-19 1995-06-19 METHOD FOR PRODUCING A PROBIOTIC DRUG RU2058681C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU95110319/13A RU2058681C1 (en) 1995-06-19 1995-06-19 METHOD FOR PRODUCING A PROBIOTIC DRUG

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU95110319/13A RU2058681C1 (en) 1995-06-19 1995-06-19 METHOD FOR PRODUCING A PROBIOTIC DRUG

Publications (2)

Publication Number Publication Date
RU95110319A true RU95110319A (en) 1996-03-27
RU2058681C1 RU2058681C1 (en) 1996-04-20

Family

ID=48451226

Family Applications (1)

Application Number Title Priority Date Filing Date
RU95110319/13A RU2058681C1 (en) 1995-06-19 1995-06-19 METHOD FOR PRODUCING A PROBIOTIC DRUG

Country Status (1)

Country Link
RU (1) RU2058681C1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998013068A1 (en) * 1996-09-26 1998-04-02 Vladimir Borisovich Kuperman Medicinal prophylactic 'trisan'

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998013068A1 (en) * 1996-09-26 1998-04-02 Vladimir Borisovich Kuperman Medicinal prophylactic 'trisan'

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