KR970025608A - Soft sugar dragee and manufacturing method - Google Patents

Abstract

The present invention relates to a chewable soft dragee used as a pharmaceutical or functional food containing live bacteria, and a method for manufacturing the same, in the conventional case, the stability of which is lowered by oxygen and moisture in the air, as well as during the tableting and coating process. Due to the high temperature, there is a problem that the development of the product is difficult due to low stability of live bacteria.In view of this, the probiotic is made into soft dragee to preserve the stability of live bacteria in powders, granules and tablets. The present invention provides a soft sugar-coated tablet and a method of manufacturing the same, which prevent the degradation of viable microorganisms and have stability and convenience that can be easily taken without water as a medicine or food regardless of time and place.

Description

Soft sugar dragee and manufacturing method

As this is a public information case, the full text was not included.

Claims (7)

Soft sugar made of sugar so that it can be chewed by using live bacteria with a formal action as a soft sugar made. The group of intestinal beneficial bacteria according to claim 1, wherein the live bacteria belong to Crosstrium vitalisum, Straptococcus fascium, Bacillus subtilis, Lactobacillus asidophilus, Lactobacillus beepferus, Lactobacillus sporogenes and the like. Soft sugar dragee, characterized in that at least one species of vitamin B ₁ , B ₂ , B ₃ , B ₅ , B ₆ , B ₁₂ C selected from at least one species. In claim 2 wherein one party of viable cells is ^{1 × 10 4 ~ 1 × 10} 11 pieces, vitamin B ₁ is 0.1~l0mg, vitamin B ₂ is 0.1~10mg vitamin B ₃ is 0.1 ~ 40mg, Vitamin B ₅ is 0.5-l0mg , Vitamin B ₆ is 0.1 ~ 40mg, Vitamin B ₁₂ is 01. ~ 400μm, Vitamin C is characterized in that 1-200mg mixed soft sugar drag. A method for producing a soft sugar-coated tablet comprising the steps of preparing a central tablet with probiotics and vitamins, waterproof coating with a coating agent, subcoating with a dispersing agent, smoothing with syrup solution, and coloring with a pigment solution. The water-insoluble dispersing agent according to claim 4, wherein the water-soluble dispersing agent used in dragging is selected from at least one selected from white sugar, glucose, fructose, mannitol, textine, sorbitol, oligosaccharide, and the like, and less than 10% of the dispersing agent is talc, A method for producing a soft dragee, characterized in that at least one selected from precipitated calcium carbonate, kaolin, calcium sulfate and the like. The method of claim 4, wherein the syrup used for the sub-coating and the smoothing is selected from at least one selected from white sugar, glucose, fructose, mannitol, textine, sorbitol, oligosaccharide, and the like. The water-insoluble suspending agent according to claim 4, wherein the spray liquid used for dragging in the spraying method is selected from at least one selected from white sugar, glucose, fructose, mannitol, textine, sorbitol, and oligosaccharide and used less than 10% of talc, precipitated carbonic acid. A method for producing a soft dragee, characterized in that at least one selected from calcium, starch, kaolin and calcium sulfate. ※ Note: The disclosure is based on the initial application.