RU94039363A - Method of production of composite medicinal preparation in solid gelatin capsules - Google Patents
Method of production of composite medicinal preparation in solid gelatin capsulesInfo
- Publication number
- RU94039363A RU94039363A RU94039363/14A RU94039363A RU94039363A RU 94039363 A RU94039363 A RU 94039363A RU 94039363/14 A RU94039363/14 A RU 94039363/14A RU 94039363 A RU94039363 A RU 94039363A RU 94039363 A RU94039363 A RU 94039363A
- Authority
- RU
- Russia
- Prior art keywords
- preparation
- production
- gelatin capsules
- citrapar
- composite
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
FIELD: chemicopharmaceutical industry, in particular, production of composite medicinal preparation of analgetic, antipyretic, anti-inflammatory effect in solid gelatin capsules. SUBSTANCE: the method of production of a stable and nontoxic medicinal form of composite preparation "Citrapar", containing acetylsalicylic acid, paracetamol, caffeine, citric acid consists in the use of powders of acting substances. Powders of acting substances are sifted, mixed with auxiliary substances and dosed into solid gelatin capsules. Talc (2.5 to 3.0%), polyvinylpyrrolidone and acrosil (0.65 to 0.7%) are used as auxiliary substances, which makes it possible to obtain a mass for filling the capsules, providing the necessary weighed portion and homogeneity of dosage. To obtain a less toxic medicinal form, paracetamol (33 to 41%) is introduced in the preparation instead of phenacetin. The offered method of production of medicinal preparation "Citrapar" in solid gelatin capsules excludes any contact of the composite mix with moisture, provides for production of medicinal preparation initially containing a lower percentage of free salicylic acid. EFFECT: the "Citrapar" powdered dosed preparation features an enhanced bioaccessibility and stability in storage.
Claims (1)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU94039363/14A RU2110258C1 (en) | 1994-10-20 | 1994-10-20 | Method of preparing the combined medicinal preparation in solid gelatinous capsules |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU94039363/14A RU2110258C1 (en) | 1994-10-20 | 1994-10-20 | Method of preparing the combined medicinal preparation in solid gelatinous capsules |
Publications (2)
Publication Number | Publication Date |
---|---|
RU94039363A true RU94039363A (en) | 1996-09-20 |
RU2110258C1 RU2110258C1 (en) | 1998-05-10 |
Family
ID=20161925
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU94039363/14A RU2110258C1 (en) | 1994-10-20 | 1994-10-20 | Method of preparing the combined medicinal preparation in solid gelatinous capsules |
Country Status (1)
Country | Link |
---|---|
RU (1) | RU2110258C1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110954386A (en) * | 2019-12-31 | 2020-04-03 | 中国计量科学研究院 | Chromium element standard substance in form of medicinal hollow capsule, preparation method thereof, kit combination thereof and method for measuring chromium element content |
-
1994
- 1994-10-20 RU RU94039363/14A patent/RU2110258C1/en active IP Right Revival
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110954386A (en) * | 2019-12-31 | 2020-04-03 | 中国计量科学研究院 | Chromium element standard substance in form of medicinal hollow capsule, preparation method thereof, kit combination thereof and method for measuring chromium element content |
CN110954386B (en) * | 2019-12-31 | 2022-08-19 | 中国计量科学研究院 | Chromium element standard substance in form of medicinal hollow capsule, preparation method thereof, kit combination thereof and method for measuring chromium element content |
Also Published As
Publication number | Publication date |
---|---|
RU2110258C1 (en) | 1998-05-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20041021 |
|
MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20061021 |
|
NF4A | Reinstatement of patent |
Effective date: 20080220 |