RU94021365A - DERIVATIVES OF METHYLPIPERAZINAZEPENINE, METHOD FOR THEIR PRODUCTION, PHARMACEUTICAL COMPOSITION ON THEIR BASIS AND USE OF DERIVATIVES AS A PHARMACEUTICAL ACTIVE SUBSTANCE - Google Patents

DERIVATIVES OF METHYLPIPERAZINAZEPENINE, METHOD FOR THEIR PRODUCTION, PHARMACEUTICAL COMPOSITION ON THEIR BASIS AND USE OF DERIVATIVES AS A PHARMACEUTICAL ACTIVE SUBSTANCE

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Publication number
RU94021365A
RU94021365A RU94021365/04A RU94021365A RU94021365A RU 94021365 A RU94021365 A RU 94021365A RU 94021365/04 A RU94021365/04 A RU 94021365/04A RU 94021365 A RU94021365 A RU 94021365A RU 94021365 A RU94021365 A RU 94021365A
Authority
RU
Russia
Prior art keywords
derivatives
methylpiperazinazepenine
basis
production
active substance
Prior art date
Application number
RU94021365/04A
Other languages
Russian (ru)
Other versions
RU2111966C1 (en
Inventor
Фернанд Льежуа Жан-Франсуа
Эли Деларж Жак
Original Assignee
Терабель Ресич С.А. / Н.В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from BE9000914A external-priority patent/BE1004596A4/en
Application filed by Терабель Ресич С.А. / Н.В. filed Critical Терабель Ресич С.А. / Н.В.
Publication of RU94021365A publication Critical patent/RU94021365A/en
Application granted granted Critical
Publication of RU2111966C1 publication Critical patent/RU2111966C1/en

Links

Claims (1)

Предложены производные метилпиперазиноазепина общей формулы
Figure 00000001

в которой символы X, R1, R2, N1 и N2 имеют различные значения, их фармацевтически приемлемые соли, их получение и их применение, а также способы их получения, фармацевтические композиции на их основе, применение их как агента, проявляющего активность в отношении ЦНС.Methylpiperazinoazepine derivatives of the general formula are proposed.
Figure 00000001

in which the symbols X, R 1 , R 2 , N 1 and N 2 have different meanings, their pharmaceutically acceptable salts, their preparation and their use, as well as methods for their preparation, pharmaceutical compositions based on them, their use as an agent exhibiting activity against the central nervous system.
RU94021365A 1990-09-26 1991-10-10 Derivatives of methylpiperazine-azepine or their pharmaceutically acceptable salts RU2111966C1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
BE9000914A BE1004596A4 (en) 1990-09-26 1990-09-26 Methylpiperazinoazepine DERIVATIVES, PREPARATION AND USE.
CA002120229A CA2120229C (en) 1990-09-26 1991-10-10 Methylpiperazinoazepine derivatives, their preparation and their use
PCT/BE1991/000073 WO1993007143A1 (en) 1990-09-26 1991-10-10 Methylpiperazinoazepine derivatives, their preparation and use
BEPCT/BE91/00073 1991-10-10
HK98106195A HK1006970A1 (en) 1990-09-26 1998-06-23 Methylpiperazinoazepine derivatives their preparation and use

Publications (2)

Publication Number Publication Date
RU94021365A true RU94021365A (en) 1995-12-20
RU2111966C1 RU2111966C1 (en) 1998-05-27

Family

ID=27159764

Family Applications (1)

Application Number Title Priority Date Filing Date
RU94021365A RU2111966C1 (en) 1990-09-26 1991-10-10 Derivatives of methylpiperazine-azepine or their pharmaceutically acceptable salts

Country Status (14)

Country Link
EP (1) EP0607129B1 (en)
AT (1) ATE126799T1 (en)
BE (1) BE1004596A4 (en)
CA (1) CA2120229C (en)
DE (1) DE69112432T2 (en)
DK (1) DK0607129T3 (en)
EE (1) EE02942B1 (en)
ES (1) ES2080336T3 (en)
GR (1) GR3017951T3 (en)
HK (1) HK1006970A1 (en)
LT (1) LT3231B (en)
LV (1) LV10098B (en)
RU (1) RU2111966C1 (en)
WO (1) WO1993007143A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5700445A (en) * 1994-12-12 1997-12-23 Allelix Biopharmaceuticals, Inc. N-methyl piperazine compounds having dopamine receptor affinity
US5561127A (en) * 1994-12-19 1996-10-01 Allelix Biopharmaceuticals, Inc. Muscarinic receptor ligands
FR2850654A1 (en) * 2003-02-03 2004-08-06 Servier Lab NOVEL TRICYCLIC AZEPINE DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
CN1913900B (en) * 2003-12-22 2010-11-24 阿卡蒂亚药品公司 Amino bustituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders
KR101157881B1 (en) 2003-12-22 2012-07-06 아카디아 파마슈티칼스 인코포레이티드 AMINO SUBSTITUTED DIARYL[a,d]CYCLOHEPTENE ANALOGS AS MUSCARINIC AGONISTS AND METHODS OF TREATMENT OF NEUROPSYCHIATRIC DISORDERS
CN102807574B (en) * 2011-05-30 2015-09-02 长春吉大天元化学技术股份有限公司 New pyridine sulphur nitrogen seven-membered ring derivative as antitumor drug, and its preparation method and application
CN107382907A (en) * 2017-06-21 2017-11-24 温州医科大学 A kind of 11 methyldiphenyls simultaneously [b, f] [1,4] selenium azepine compound and preparation method

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7403657A (en) * 1973-03-23 1974-09-25
US3872122A (en) * 1973-04-16 1975-03-18 Bristol Myers Co 11 H-Pyrimido{8 4,5-b{9 {8 1,4{9 benzodiazepines
GB1587128A (en) 1977-04-07 1981-04-01 Hexachimie Benzothiazepine derivatives
IT7851496A0 (en) * 1977-10-31 1978-10-13 Sandoz Ag PYRAZINOBENZOXAZEPINES THEIR PREPARATION AND THEIR MEDICAL USE
CH643263A5 (en) * 1979-05-11 1984-05-30 Sandoz Ag BENZODIAZEPINE, THEIR PRODUCTION AND USE.
GB8819059D0 (en) * 1988-08-11 1988-09-14 Lilly Industries Ltd Benzodiazepine compounds & their use as pharmaceuticals
US4940704A (en) 1989-08-16 1990-07-10 Hoechst-Roussel Pharmaceutical Inc. Pyrido[3,4-b][1,4]benzoxazepines

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