DK0607129T3 - Methylpiperazinoazepine derivatives, their preparation and their use - Google Patents

Methylpiperazinoazepine derivatives, their preparation and their use

Info

Publication number
DK0607129T3
DK0607129T3 DK91916897.1T DK91916897T DK0607129T3 DK 0607129 T3 DK0607129 T3 DK 0607129T3 DK 91916897 T DK91916897 T DK 91916897T DK 0607129 T3 DK0607129 T3 DK 0607129T3
Authority
DK
Denmark
Prior art keywords
methylpiperazinoazepine
derivatives
preparation
pharmaceutically acceptable
general formula
Prior art date
Application number
DK91916897.1T
Other languages
Danish (da)
Inventor
Jean-Francois Fernand Liegeois
Jacques Elie Delarge
Original Assignee
Therabel Research Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Therabel Research Sa filed Critical Therabel Research Sa
Application granted granted Critical
Publication of DK0607129T3 publication Critical patent/DK0607129T3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D517/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms
    • C07D517/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms in which the condensed system contains two hetero rings
    • C07D517/04—Ortho-condensed systems

Abstract

Methylpiperazinoazepine derivatives of general formula (I), wherein X, R1, R2, N1 and N2 have various meanings, pharmaceutically acceptable salts thereof, and their preparation and use, are described.
DK91916897.1T 1990-09-26 1991-10-10 Methylpiperazinoazepine derivatives, their preparation and their use DK0607129T3 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
BE9000914A BE1004596A4 (en) 1990-09-26 1990-09-26 Methylpiperazinoazepine DERIVATIVES, PREPARATION AND USE.
CA002120229A CA2120229C (en) 1990-09-26 1991-10-10 Methylpiperazinoazepine derivatives, their preparation and their use
PCT/BE1991/000073 WO1993007143A1 (en) 1990-09-26 1991-10-10 Methylpiperazinoazepine derivatives, their preparation and use
HK98106195A HK1006970A1 (en) 1990-09-26 1998-06-23 Methylpiperazinoazepine derivatives their preparation and use

Publications (1)

Publication Number Publication Date
DK0607129T3 true DK0607129T3 (en) 1995-12-18

Family

ID=27159764

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91916897.1T DK0607129T3 (en) 1990-09-26 1991-10-10 Methylpiperazinoazepine derivatives, their preparation and their use

Country Status (14)

Country Link
EP (1) EP0607129B1 (en)
AT (1) ATE126799T1 (en)
BE (1) BE1004596A4 (en)
CA (1) CA2120229C (en)
DE (1) DE69112432T2 (en)
DK (1) DK0607129T3 (en)
EE (1) EE02942B1 (en)
ES (1) ES2080336T3 (en)
GR (1) GR3017951T3 (en)
HK (1) HK1006970A1 (en)
LT (1) LT3231B (en)
LV (1) LV10098B (en)
RU (1) RU2111966C1 (en)
WO (1) WO1993007143A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5700445A (en) * 1994-12-12 1997-12-23 Allelix Biopharmaceuticals, Inc. N-methyl piperazine compounds having dopamine receptor affinity
US5561127A (en) * 1994-12-19 1996-10-01 Allelix Biopharmaceuticals, Inc. Muscarinic receptor ligands
FR2850654A1 (en) * 2003-02-03 2004-08-06 Servier Lab NOVEL TRICYCLIC AZEPINE DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
SG133606A1 (en) * 2003-12-22 2007-07-30 Acadia Pharm Inc Amino substituted diaryl [a,d] cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders
CN1913900B (en) * 2003-12-22 2010-11-24 阿卡蒂亚药品公司 Amino bustituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders
CN102807574B (en) * 2011-05-30 2015-09-02 长春吉大天元化学技术股份有限公司 New pyridine sulphur nitrogen seven-membered ring derivative as antitumor drug, and its preparation method and application
CN107382907A (en) * 2017-06-21 2017-11-24 温州医科大学 A kind of 11 methyldiphenyls simultaneously [b, f] [1,4] selenium azepine compound and preparation method

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7403657A (en) * 1973-03-23 1974-09-25
US3872122A (en) * 1973-04-16 1975-03-18 Bristol Myers Co 11 H-Pyrimido{8 4,5-b{9 {8 1,4{9 benzodiazepines
GB1587128A (en) 1977-04-07 1981-04-01 Hexachimie Benzothiazepine derivatives
IT7851496A0 (en) * 1977-10-31 1978-10-13 Sandoz Ag PYRAZINOBENZOXAZEPINES THEIR PREPARATION AND THEIR MEDICAL USE
CH643263A5 (en) * 1979-05-11 1984-05-30 Sandoz Ag BENZODIAZEPINE, THEIR PRODUCTION AND USE.
GB8819059D0 (en) * 1988-08-11 1988-09-14 Lilly Industries Ltd Benzodiazepine compounds & their use as pharmaceuticals
US4940704A (en) 1989-08-16 1990-07-10 Hoechst-Roussel Pharmaceutical Inc. Pyrido[3,4-b][1,4]benzoxazepines

Also Published As

Publication number Publication date
DE69112432T2 (en) 1996-02-01
DE69112432D1 (en) 1995-09-28
EE02942B1 (en) 1996-10-15
GR3017951T3 (en) 1996-02-29
LV10098A (en) 1994-05-10
BE1004596A4 (en) 1992-12-22
RU2111966C1 (en) 1998-05-27
CA2120229A1 (en) 1993-04-15
LV10098B (en) 1994-10-20
ES2080336T3 (en) 1996-02-01
EP0607129B1 (en) 1995-08-23
LT3231B (en) 1995-04-25
CA2120229C (en) 2002-04-09
LTIP378A (en) 1994-09-25
HK1006970A1 (en) 1999-03-26
WO1993007143A1 (en) 1993-04-15
EP0607129A1 (en) 1994-07-27
ATE126799T1 (en) 1995-09-15

Similar Documents

Publication Publication Date Title
DK308986D0 (en) PICOLIN DERIVATIVES
NO853699L (en) TETRALIN DERIVATIVES, MANUFACTURING AND USING THEREOF.
NO924650D0 (en) DIALCOXY-PYRIDINYL-BENZIMIDAZOLD DERIVATIVES, PROCEDURES FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL USE
TR200200579T2 (en) Amino-thyrazolpyridine derivatives.
MD4B1 (en) Herbicide remedy
DK0977741T3 (en) Substituted phenyl derivatives, their preparation and use
SE8900192D0 (en) DIDEOXIDIDE HYDROCARBOCYCLIC NUCLEOSIDES
DK454086D0 (en) QUINOLINE DERIVATIVES AND THEIR USE
DK24984A (en) 6- (ACYLAMINOARYL) -3 (2H) -PYRIDAZINO DERIVATIVES AND THEIR USE AS MEDICINES
DK0435749T3 (en) 2-Aminopyrimidine-4-carboxamide derivatives, their preparation and their therapeutic use
DK0387821T3 (en) 2-Alkyl-4-arylmethylquinolines, their uses and drugs prepared therewith
TR199700206A2 (en) Fluoralkyl- and fluoroalkoxy-substituted heterocyclic bradykinin-antagonists, process for their manufacture and their use.
DK0607129T3 (en) Methylpiperazinoazepine derivatives, their preparation and their use
SE7811455L (en) 2-IMINO-IMIDAZOLIDINE DERIVATIVE
ATE330958T1 (en) PYRAZINO 1'2':1,6ÖPYRIDO 3,4-BÖINDOL DERIVATIVES
NO921563D0 (en) THERAPEUTIC ACTIVE AMINOPYRIMIDINE DERIVATIVES, PROCEDURES FOR THEIR PREPARATION AND USE THEREOF
DK0589908T3 (en) Aminoalkyl-substituted thiazolin-2-ones, their preparation and their use
DK242089A (en) APPLICATION OF PYRIMIDO OE6,1-AAA-ISOQUINOLIN-4-ON DERIVATIVES FOR PREVENTING HAIR LOSS AND INCREASING HAIR GROWTH
NO20010626D0 (en) N-substituted azabicycloheptane derivatives, their preparation and use
NO911798D0 (en) 3'-DEAMINO-4'-DEOXY-4'-AMINO-8-FLUORANTRACYCLINES AND THEIR PREPARATION.
ATE92069T1 (en) 4-SUBSTITUTED 10-CYANOMEHYLENEPYRROLO(4,3-E>BENZOAZEPINES.
NO912526L (en) CEPHALOSPORINE DERIVATIVES AND PROCEDURES FOR THEIR PREPARATION.
ATE111099T1 (en) ERGOLINE DERIVATIVES.
DK276590D0 (en) SUBSTITUTED AMINOQUINAZOLINE DERIVATIVES, THEIR PREPARATION AND USE
DK338589D0 (en) MORPHOLINO DERIVATIVES OF RHODOMYCINES, THEIR PREPARATION AND USE