LV10098A - Derivatives of methylpiperazinepeptin by their acquisition and use - Google Patents

Derivatives of methylpiperazinepeptin by their acquisition and use

Info

Publication number
LV10098A
LV10098A LV920398A LV920398A LV10098A LV 10098 A LV10098 A LV 10098A LV 920398 A LV920398 A LV 920398A LV 920398 A LV920398 A LV 920398A LV 10098 A LV10098 A LV 10098A
Authority
LV
Latvia
Prior art keywords
derivatives
methylpiperazinepeptin
acquisition
methylpiperazinoazepine
preparation
Prior art date
Application number
LV920398A
Other languages
Latvian (lv)
Other versions
LV10098B (en
Inventor
Jean-Francois Fernand Liegeois
Jacques Elie Delarge
Original Assignee
Therabel Research Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Therabel Research Sa filed Critical Therabel Research Sa
Publication of LV10098A publication Critical patent/LV10098A/en
Publication of LV10098B publication Critical patent/LV10098B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D517/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms
    • C07D517/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms in which the condensed system contains two hetero rings
    • C07D517/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Methylpiperazinoazepine derivatives of general formula (I), wherein X, R1, R2, N1 and N2 have various meanings, pharmaceutically acceptable salts thereof, and their preparation and use, are described.
LVP-92-398A 1990-09-26 1992-12-23 Methylpiperazinoazepine derivatives, preparation and use thereof LV10098B (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
BE9000914A BE1004596A4 (en) 1990-09-26 1990-09-26 Methylpiperazinoazepine DERIVATIVES, PREPARATION AND USE.
CA002120229A CA2120229C (en) 1990-09-26 1991-10-10 Methylpiperazinoazepine derivatives, their preparation and their use
PCT/BE1991/000073 WO1993007143A1 (en) 1990-09-26 1991-10-10 Methylpiperazinoazepine derivatives, their preparation and use
HK98106195A HK1006970A1 (en) 1990-09-26 1998-06-23 Methylpiperazinoazepine derivatives their preparation and use

Publications (2)

Publication Number Publication Date
LV10098A true LV10098A (en) 1994-05-10
LV10098B LV10098B (en) 1994-10-20

Family

ID=27159764

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-92-398A LV10098B (en) 1990-09-26 1992-12-23 Methylpiperazinoazepine derivatives, preparation and use thereof

Country Status (14)

Country Link
EP (1) EP0607129B1 (en)
AT (1) ATE126799T1 (en)
BE (1) BE1004596A4 (en)
CA (1) CA2120229C (en)
DE (1) DE69112432T2 (en)
DK (1) DK0607129T3 (en)
EE (1) EE02942B1 (en)
ES (1) ES2080336T3 (en)
GR (1) GR3017951T3 (en)
HK (1) HK1006970A1 (en)
LT (1) LT3231B (en)
LV (1) LV10098B (en)
RU (1) RU2111966C1 (en)
WO (1) WO1993007143A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5700445A (en) * 1994-12-12 1997-12-23 Allelix Biopharmaceuticals, Inc. N-methyl piperazine compounds having dopamine receptor affinity
US5561127A (en) * 1994-12-19 1996-10-01 Allelix Biopharmaceuticals, Inc. Muscarinic receptor ligands
FR2850654A1 (en) * 2003-02-03 2004-08-06 Servier Lab NOVEL TRICYCLIC AZEPINE DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
CN1913900B (en) * 2003-12-22 2010-11-24 阿卡蒂亚药品公司 Amino bustituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders
CN101962369A (en) 2003-12-22 2011-02-02 阿卡蒂亚药品公司 Amino diaryl [a, d] the suberene analogue that replaces is as the purposes of muscarinic agonist and the methods of treatment of neuropsychiatric disease
CN102807574B (en) * 2011-05-30 2015-09-02 长春吉大天元化学技术股份有限公司 New pyridine sulphur nitrogen seven-membered ring derivative as antitumor drug, and its preparation method and application
CN107382907A (en) * 2017-06-21 2017-11-24 温州医科大学 A kind of 11 methyldiphenyls simultaneously [b, f] [1,4] selenium azepine compound and preparation method

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7403657A (en) * 1973-03-23 1974-09-25
US3872122A (en) * 1973-04-16 1975-03-18 Bristol Myers Co 11 H-Pyrimido{8 4,5-b{9 {8 1,4{9 benzodiazepines
GB1587128A (en) 1977-04-07 1981-04-01 Hexachimie Benzothiazepine derivatives
IT7851496A0 (en) * 1977-10-31 1978-10-13 Sandoz Ag PYRAZINOBENZOXAZEPINES THEIR PREPARATION AND THEIR MEDICAL USE
CH643263A5 (en) * 1979-05-11 1984-05-30 Sandoz Ag BENZODIAZEPINE, THEIR PRODUCTION AND USE.
GB8819059D0 (en) * 1988-08-11 1988-09-14 Lilly Industries Ltd Benzodiazepine compounds & their use as pharmaceuticals
US4940704A (en) 1989-08-16 1990-07-10 Hoechst-Roussel Pharmaceutical Inc. Pyrido[3,4-b][1,4]benzoxazepines

Also Published As

Publication number Publication date
DE69112432T2 (en) 1996-02-01
ATE126799T1 (en) 1995-09-15
EP0607129B1 (en) 1995-08-23
DE69112432D1 (en) 1995-09-28
EE02942B1 (en) 1996-10-15
CA2120229A1 (en) 1993-04-15
LT3231B (en) 1995-04-25
HK1006970A1 (en) 1999-03-26
EP0607129A1 (en) 1994-07-27
RU2111966C1 (en) 1998-05-27
LTIP378A (en) 1994-09-25
LV10098B (en) 1994-10-20
BE1004596A4 (en) 1992-12-22
GR3017951T3 (en) 1996-02-29
ES2080336T3 (en) 1996-02-01
DK0607129T3 (en) 1995-12-18
WO1993007143A1 (en) 1993-04-15
CA2120229C (en) 2002-04-09

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