RU93004445A - Новые 2-циано 3-гидроксиенамидные производные, способ их получения, их применение в качестве медикаментов, содержащие их фармацевтические композиции и новые полученные промежуточные продукты - Google Patents
Новые 2-циано 3-гидроксиенамидные производные, способ их получения, их применение в качестве медикаментов, содержащие их фармацевтические композиции и новые полученные промежуточные продуктыInfo
- Publication number
- RU93004445A RU93004445A RU93004445/04A RU93004445A RU93004445A RU 93004445 A RU93004445 A RU 93004445A RU 93004445/04 A RU93004445/04 A RU 93004445/04A RU 93004445 A RU93004445 A RU 93004445A RU 93004445 A RU93004445 A RU 93004445A
- Authority
- RU
- Russia
- Prior art keywords
- new
- hydroxyenamide
- cyano
- derivatives
- medication
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title claims 2
- 239000003814 drug Substances 0.000 title 1
Claims (1)
- Изобретение относится к новым 2-циано-3-гидроксиенамидным производным, к способу их получения и фармацевтической композиции на их основе.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9200275.7 | 1992-01-08 | ||
GB929200275A GB9200275D0 (en) | 1992-01-08 | 1992-01-08 | Chemical compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
RU93004445A true RU93004445A (ru) | 1995-08-20 |
RU2112772C1 RU2112772C1 (ru) | 1998-06-10 |
Family
ID=10708234
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU93004445A RU2112772C1 (ru) | 1992-01-08 | 1993-01-06 | Производные 2-циано-3-гидроксиенамидов, способы их получения, фармацевтическая композиция на их основе |
Country Status (22)
Country | Link |
---|---|
US (1) | US5308865A (ru) |
EP (1) | EP0551230B1 (ru) |
JP (1) | JP3145824B2 (ru) |
KR (1) | KR100276182B1 (ru) |
CN (1) | CN1034499C (ru) |
AT (1) | ATE125252T1 (ru) |
AU (1) | AU652088B2 (ru) |
BR (1) | BR9300035A (ru) |
CA (1) | CA2086908C (ru) |
CZ (1) | CZ285586B6 (ru) |
DE (1) | DE69300261T2 (ru) |
DK (1) | DK0551230T3 (ru) |
ES (1) | ES2074916T3 (ru) |
FI (1) | FI111361B (ru) |
GB (1) | GB9200275D0 (ru) |
HU (1) | HU215843B (ru) |
IL (1) | IL104225A (ru) |
NO (1) | NO179444C (ru) |
NZ (1) | NZ245631A (ru) |
RU (1) | RU2112772C1 (ru) |
TW (1) | TW234116B (ru) |
ZA (1) | ZA93134B (ru) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994024095A1 (en) * | 1993-04-16 | 1994-10-27 | Abbott Laboratories | Immunosuppressive agents |
GB9313365D0 (en) * | 1993-06-29 | 1993-08-11 | Roussel Lab Ltd | Chemical compounds |
GB9322781D0 (en) * | 1993-11-04 | 1993-12-22 | Roussel Lab Ltd | Aromatic amides |
US6335356B1 (en) | 1994-01-07 | 2002-01-01 | Sugen, Inc. | Method of treating a patient by parenteral administration of a lipophilic compound |
US5700823A (en) * | 1994-01-07 | 1997-12-23 | Sugen, Inc. | Treatment of platelet derived growth factor related disorders such as cancers |
US5610173A (en) * | 1994-01-07 | 1997-03-11 | Sugen, Inc. | Formulations for lipophilic compounds |
US5721277A (en) * | 1995-04-21 | 1998-02-24 | Sugen, Inc. | Compounds and methods for inhibiting hyper-proliferative cell growth |
GB9520092D0 (en) * | 1995-10-02 | 1995-12-06 | Hoechst Roussel Ltd | Chemical compounds |
DE19539638A1 (de) * | 1995-10-25 | 1997-04-30 | Hoechst Ag | Die Verwendung von Isoxazol- und Crotonsäureamidderivaten zur Behandlung von Krebserkrankungen |
DE19547648A1 (de) * | 1995-12-20 | 1997-06-26 | Hoechst Ag | Zubereitung, enthaltend High Density Lipoproteine und Crotonsäureamidderivate |
US5981536A (en) * | 1996-07-31 | 1999-11-09 | Hoechst Aktiengesellschaft | Use of xanthine derivatives for the modulation of apoptosis |
US6011051A (en) * | 1996-07-31 | 2000-01-04 | Hoechst Aktiengesellschaft | Use of isoxazole and crotonamide derivatives for the modulation of apoptosis |
US5856330A (en) * | 1996-07-31 | 1999-01-05 | Hoechst Aktiengesellschaft | Use of xanthine derivatives for the inhibition of dephosphorylation of cofilin |
DE19702988A1 (de) | 1997-01-28 | 1998-07-30 | Hoechst Ag | Isoxazol- und Crotonsäureamidderivate und deren Verwendung als Arzneimittel und Diagnostika |
DE19711800A1 (de) * | 1997-03-21 | 1998-09-24 | Hoechst Ag | Verlängerung der Expression von transgenen Proteinen durch immunmodulierende Behandlung |
US6316479B1 (en) | 1997-05-19 | 2001-11-13 | Sugen, Inc. | Isoxazole-4-carboxamide compounds active against protein tryosine kinase related disorders |
MXPA00010150A (es) * | 1998-04-17 | 2002-05-14 | Parker Hughes Inst | Inhibidores de btk y metodos para su identificacion y uso. |
US6303652B1 (en) | 1998-08-21 | 2001-10-16 | Hughes Institute | BTK inhibitors and methods for their identification and use |
RU2004133347A (ru) * | 2002-04-16 | 2005-05-10 | Фудзисава Фармасьютикал Ко.,Лтд. (Jp) | Лекарственное средство для профилактики и/или лечения хронического отторжения |
US20060217440A1 (en) * | 2003-03-24 | 2006-09-28 | Hiroki Omori | Porcess for production of 2-cyano-3-hydroxy-n-(4-trifluoromethylphenyl)hept-2-en-6-ynamide and process for production of polymorphs thereof |
EP1723179A1 (en) * | 2004-03-05 | 2006-11-22 | Astellas Pharma Inc. | Anti fk778 antibodies and high sensitive immunoassay methods |
DE102005017592A1 (de) * | 2005-04-16 | 2006-10-19 | Lindner, Jürgen, Dr. med. | Darreichungsformen und Kombinationspräparate von Pyrimidinbiosyntheseinhibitoren zur Erzielung zusätzlicher Wirkungen auf das Immunsystem |
CN101969951B (zh) * | 2007-11-16 | 2012-10-31 | 雅培制药有限公司 | 化合物在制备治疗关节炎的药物中的方法 |
LT2632451T (lt) | 2010-10-29 | 2018-02-12 | Algiax Pharmaceuticals Gmbh | Malononitrilamidų panaudojimas esant neuropatiniam skausmui |
CN105916522A (zh) | 2013-11-22 | 2016-08-31 | 建新公司 | 用于治疗神经变性疾病的新方法 |
CN112979509B (zh) * | 2021-03-10 | 2022-04-22 | 江西师范大学 | 一种三氟甲磺酰基炔酰胺类化合物及其制备方法和用途 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR484223A (fr) * | 1916-03-21 | 1917-09-14 | Zenith Carburateur Soc Du | Perfectionnements aux carburateurs de moteurs à explosions |
NL186239B (nl) * | 1975-06-05 | Hoechst Ag | Werkwijze voor de bereiding van een geneesmiddel met antiflogistische en/of analgetische werking, alsmede werkwijze voor de bereiding van een 2-hydroxyethylideencyaanazijnzuuranilide geschikt voor toepassing bij deze werkwijze. | |
DE2555789A1 (de) * | 1975-12-11 | 1977-07-07 | Hoechst Ag | Neue cyanessigsaeureanilid-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel |
US4346097A (en) * | 1980-09-30 | 1982-08-24 | Warner-Lambert Company | Method for treating convulsions with pyrazole-4-carboxamide derivatives |
DE3534440A1 (de) * | 1985-09-27 | 1987-04-02 | Hoechst Ag | Arzneimittel gegen chronische graft-versus-host-krankheiten sowie gegen autoimmunerkrankungen, insbesondere systemischen lupus erythematodes |
GB8619432D0 (en) * | 1986-08-08 | 1986-09-17 | Lilly Industries Ltd | Pharmaceutical compounds |
DK0527736T3 (da) * | 1990-05-18 | 1997-10-20 | Hoechst Ag | Isoxazol-4-carboxylsyreamider og hydroxyalkyliden-cyanoacetamider, lægemidler indeholdende disse forbindelser og anvendelsen af disse lægemidler. |
IL99811A (en) * | 1990-10-30 | 1996-03-31 | Roussel Uclaf | 3-Cycloalkyl-propanamides, tautomeric forms of these, their salts, method of preparation, use as drugs and preparations containing them |
-
1992
- 1992-01-08 GB GB929200275A patent/GB9200275D0/en active Pending
- 1992-12-22 CZ CS923826A patent/CZ285586B6/cs not_active IP Right Cessation
- 1992-12-24 IL IL104225A patent/IL104225A/en not_active IP Right Cessation
-
1993
- 1993-01-06 RU RU93004445A patent/RU2112772C1/ru active
- 1993-01-06 AU AU31035/93A patent/AU652088B2/en not_active Expired
- 1993-01-06 US US08/001,564 patent/US5308865A/en not_active Expired - Lifetime
- 1993-01-07 EP EP93400024A patent/EP0551230B1/fr not_active Expired - Lifetime
- 1993-01-07 AT AT93400024T patent/ATE125252T1/de active
- 1993-01-07 FI FI930048A patent/FI111361B/fi not_active IP Right Cessation
- 1993-01-07 NO NO930036A patent/NO179444C/no not_active IP Right Cessation
- 1993-01-07 CA CA002086908A patent/CA2086908C/en not_active Expired - Lifetime
- 1993-01-07 DE DE69300261T patent/DE69300261T2/de not_active Expired - Lifetime
- 1993-01-07 JP JP01709493A patent/JP3145824B2/ja not_active Expired - Lifetime
- 1993-01-07 ES ES93400024T patent/ES2074916T3/es not_active Expired - Lifetime
- 1993-01-07 KR KR1019930000112A patent/KR100276182B1/ko not_active IP Right Cessation
- 1993-01-07 HU HU9300022A patent/HU215843B/hu unknown
- 1993-01-07 NZ NZ245631A patent/NZ245631A/en not_active IP Right Cessation
- 1993-01-07 DK DK93400024.1T patent/DK0551230T3/da active
- 1993-01-08 CN CN93100647A patent/CN1034499C/zh not_active Expired - Lifetime
- 1993-01-08 ZA ZA93134A patent/ZA93134B/xx unknown
- 1993-01-08 BR BR9300035A patent/BR9300035A/pt not_active Application Discontinuation
- 1993-03-06 TW TW082101697A patent/TW234116B/zh not_active IP Right Cessation
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