RU2792118C1 - Method for treatment of respiratory syncytial infection of cattle - Google Patents

Abstract

FIELD: veterinary medicine.

SUBSTANCE: invention relates to the field of veterinary medicine and is intended for therapeutic measures in outbreaks of respiratory syncytial infection of cattle. A method for treating respiratory syncytial infection of cattle is proposed, including animal vitaminization, characterized in that the diseased animals are given primary intramuscular vitaminization with Tetravit at a dose of 5 ml per head, two days later, with an interval of 12 hours, injections of one dose of Mixoferon are administered three times according to the instructions, after completion of vitaminization, a group inhalation is carried out, for group inhalation, all gates, doors and windows in the room are closed, four plastic buckets are placed equidistant from opposite gates and each other, 0.5 liters of turpentine and 1.5 liters of iodine monochloride are poured into each bucket, 70 g of aluminum wire are put and the start of the reaction is anticipated, the room is ventilated after 3 hours.

EFFECT: invention makes it possible to eliminate the symptoms of respiratory syncytial infection and completely cure sick livestock from respiratory syncytial infection of cattle.

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Description

The invention relates to the field of veterinary medicine and is intended for therapeutic measures in case of outbreaks of respiratory syncytial infection in cattle at breeding and commercial enterprises for the production of milk and beef.

Respiratory syncytial infection is a contagious acute disease of cattle, characterized by fever, acute inflammatory lesions of the respiratory organs (with symptoms of catarrhal inflammation of the respiratory mucosa), focal pneumonia and severe dry cough. The causative agent of the disease is a respiratory syncytial RNA-containing pneumovirus from the Paramixoviridae family. All sex and age groups of animals are affected, but adult cattle are most seriously ill. The disease is accompanied by fever, shortness of breath, cough, watery discharge from the nasal cavity and the development of bronchopneumonia with signs of emphysematous lung damage. Infection occurs mainly by airborne droplets, therefore, with a crowded content, all the livestock fall ill at the same time. Respiratory syncytial infection can occur as part of mixed respiratory diseases of both viral and bacterial etiology.

In this regard, traditional treatment is reduced to the use of antiviral drugs, fortification of animals (to increase nonspecific immunity) and antibiotic therapy (to prevent secondary microbial infections).

However, as practice shows, such measures are often insufficient to completely eliminate the disease, as a result of which cases of death were sometimes recorded (even among adult livestock). Therefore, in cattle breeding, there is an urgent need to develop an effective way to combat respiratory syncytial infection in cattle.

EFFECT: elimination of symptoms of respiratory syncytial infection and complete cure of sick livestock from this disease.

The technical result is achieved by a method for the treatment of respiratory syncytial infection in cattle, including fortification of animals, characterized in that diseased animals are given primary fortification intramuscularly with Tetravit at a dose of 5 ml per head, two days later, with an interval of 12 hours, injections of one dose are administered three times Mixoferon according to the instructions, then inhalation is carried out for 3 hours, consisting of iodine monochloride vapor in the amount of 1.5 l, turpentine in the amount of 0.5 l and aluminum wire in the amount of 70 g.

Saturation of the body with vitamins A, E and D helps to strengthen nonspecific immunity, in particular, retinol has a beneficial effect on the mucous membranes and epithelium of the respiratory tract. The mechanism of action of vitamin E (tocopherol) is associated with an antioxidant effect that prevents lipid peroxidation (including retinol). (Komov V.P., Shvedova V.N. Biochemistry. M., "Bud" - 640 p.).

Myxoferon has antiviral and immunomodulatory effects. Suppresses the reproduction of DNA and RNA-containing viruses, inhibiting the expression of viral genes. The immunomodulatory effect of interferon includes an effect on the cellular components of the immune system: it stimulates the lytic activity of lymphocytes, specific cytotoxic T-lymphocytes and macrophages, affects the formation of specific antibodies by B-lymphocytes, regulates the expression of KLA antigens on cell membranes and stimulates the production of its own interferon alpha. Iodine chloride belongs to the group of oxidizing agents. When interacting with aluminum, a chemical reaction occurs with the release of molecular iodine and partially chlorine into the environment. Iodine vapors have a strong disinfecting effect on bacteria (including mycobacteria), viruses, fungi, rickettsia, mycoplasmas, spores, coccidia oocysts, helminth eggs, etc. Moreover, microorganisms do not develop resistance to molecular iodine as to antibiotics. At the same time, the air of the livestock building is sanitized, which also prevents the spread of the causative agent of respiratory syncytial infection. It should be especially noted that along with iodine vapor, sick animals also inhale vapors of terpenes (turpentine oil or turpentine), which are natural phytoncides and "disinfect" the upper respiratory tract of sick animals. Thus, the multi-stage cleaning of the respiratory system of the body contributes to the deactivation of the pathogenic agent and provides a stable therapeutic effect.

Application example

The claimed method was tested during an outbreak of respiratory syncytial infection in cattle in New Agrarian Technologies LLC, Zaraisky district, Moscow region, on a dairy farm.

Animals (Holstein cows (n=160)) were kept in stalls in a typical four-row cowshed, milking system "milk pipeline", traditional feeding with a tractor-feeder, manure removal with a scraper conveyor. With the appearance of the first signs of the disease (depressed state, elevated body temperature (up to 39.5), loss of appetite) in adult dairy cows, milk production dropped sharply, shortness of breath, dry cough, rapid shallow breathing, and serous discharge from the nasal cavity appeared. In 38 heads, beginning signs of bronchitis and bronchopneumonia were noted. After laboratory confirmation of the diagnosis, a complex of therapeutic and preventive measures aimed at eliminating the disease was carried out.

On the first day, the entire livestock was fortified. Each animal was intramuscularly injected with 5 ml of tetravit, then, two days later, cows were injected intramuscularly three times with 1 dose of myxoferon with an interval of 12 hours, according to the instructions (select the area for injection, wash with warm water and an antiseptic solution, wipe the injection site with an alcohol solution, we bring the syringe to the body of the animal at a right angle, insert the needle, push the solution out of the syringe with a piston, remove the needle from the body, treat the injection site with iodine).

Finally, all livestock were subjected to group inhalation with iodine vapor, turpentine and aluminum wire.

For group inhalation:

1. Closed all the gates;

2. Equidistantly from the opposite gates and each other put two plastic buckets;

3. Pour 0.5 l of turpentine and 1.5 l of iodine monochloride into each bucket, put 70 g of aluminum wire and wait for the reaction to begin;

4. After 3 hours, the room was ventilated.

The next day after inhalation, the main symptoms of pulmonary disease disappeared in all animals, and repeated laboratory tests made a week later confirmed the complete recovery of the animals.

Thus, the proposed method of treatment ensures the elimination of the symptoms of respiratory syncytial infection in cattle and the complete cure of animals from this disease.

Claims (1)

A method for the treatment of respiratory syncytial infection in cattle, including fortification of animals, characterized in that the diseased animals are given primary fortification intramuscularly with the drug "Tetravit" at a dose of 5 ml per head, two days later with an interval of 12 hours, injections of one dose of "Mixoferon" are administered three times »According to the instructions, after the completion of vitaminization, group inhalation is carried out, for group inhalation, all gates, doors and windows in the room are closed, four plastic buckets are placed equidistant from the opposite gates and each other, poured into each bucket 0.5 liters of turpentine and 1.5 l of iodine monochloride, put 70 g of aluminum wire and wait for the reaction to begin, ventilate the room after 3 hours.