RU2771383C2 - Контролируемая пищевым рационом экспрессия нуклеиновой кислоты, кодирующей нуклеазу cas9, и ее применения - Google Patents

Контролируемая пищевым рационом экспрессия нуклеиновой кислоты, кодирующей нуклеазу cas9, и ее применения Download PDF

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RU2771383C2
RU2771383C2 RU2018142174A RU2018142174A RU2771383C2 RU 2771383 C2 RU2771383 C2 RU 2771383C2 RU 2018142174 A RU2018142174 A RU 2018142174A RU 2018142174 A RU2018142174 A RU 2018142174A RU 2771383 C2 RU2771383 C2 RU 2771383C2
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nucleic acid
cell
expression
nuclease
cas9
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RU2018142174A
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RU2018142174A (ru
RU2018142174A3 (enExample
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Филипп РАВАССАР
Жак Малле
Че СЕРГУЭРА
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Энсэрм (Энститю Насьональ Де Ла Санте Э Де Ла Решерш Медикаль)
Исм (Энститю Дю Серво Э Де Ла Моэль Эпиньер)
Сантр Насьональ Де Ла Решерш Сьянтифик (Снрс)
Сорбонн Юниверсите
Комиссарья А Л'Энержи Атомик Э Оз Энержи Альтернатив (Сеа)
Ассистанс Пюблик - Опито Де Пари
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RU2018142174A 2016-06-03 2017-06-02 Контролируемая пищевым рационом экспрессия нуклеиновой кислоты, кодирующей нуклеазу cas9, и ее применения RU2771383C2 (ru)

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Application Number Priority Date Filing Date Title
EPEP16172964 2016-06-03
EP16172964 2016-06-03
PCT/EP2017/063549 WO2017207797A1 (en) 2016-06-03 2017-06-02 Diet controlled expression of a nucleic acid encoding cas9 nuclease and uses thereof

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RU2018142174A RU2018142174A (ru) 2020-07-10
RU2018142174A3 RU2018142174A3 (enExample) 2020-09-30
RU2771383C2 true RU2771383C2 (ru) 2022-05-04

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US (2) US20190185832A1 (enExample)
JP (2) JP7436145B2 (enExample)
KR (1) KR102317622B1 (enExample)
CN (2) CN116064534A (enExample)
AU (1) AU2017275769B2 (enExample)
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CA (1) CA3025591A1 (enExample)
IL (1) IL263291B2 (enExample)
RU (1) RU2771383C2 (enExample)
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WO (1) WO2017207797A1 (enExample)

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EP3823995A4 (en) * 2018-08-01 2022-05-04 The Regents of the University of Colorado, a body corporate PROGRAMMABLE THERAPEUTIC FUSOGENE SECRETED GECTOSOME DESIGNER VESICLES FOR MACROMOLECULE RELEASE AND GENOME MODIFICATION
CN112442528B (zh) * 2019-08-30 2022-08-12 深圳华大基因股份有限公司 Loxhd1基因突变体及其应用
CN114058689B (zh) * 2020-07-30 2024-08-20 南京市妇幼保健院 一种基因突变检测试剂盒及其应用
CN119894540A (zh) * 2022-07-05 2025-04-25 营养治疗基因公司 人类t或nk细胞中转基因的受控表达用于细胞免疫疗法
WO2024100176A1 (en) * 2022-11-10 2024-05-16 Nutritheragene Controlled gene therapy of ocular diseases
CN116732043B (zh) * 2023-08-10 2023-10-17 四川省医学科学院·四川省人民医院 一种突变基因及其白内障筛查的用途与白内障筛查试剂盒

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EP3080261B1 (en) 2013-12-12 2019-05-22 The Broad Institute, Inc. Delivery, use and therapeutic applications of the crispr-cas systems and compositions for hbv and viral diseases and disorders
KR20250068794A (ko) 2013-12-12 2025-05-16 더 브로드 인스티튜트, 인코퍼레이티드 게놈 편집을 위한 ｃｒｉｓｐｒ-ｃａｓ 시스템 및 조성물의 전달, 용도 및 치료적 응용

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WO2015053995A1 (en) * 2013-10-08 2015-04-16 Elwha Llc Compositions and methods related to crispr targeting

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TOTH L.P., GERSBACH C.A., 691. A Light-Inducible CRISPR/Cas9 System for Control of Endogenous Gene Activation", Molecular Therapy, 2015, 23: S275. *
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ZHOU WENYUAN, DEITERS ALEXANDER, "Conditional control of CRISPR/Cas9 function", Angewandte Chemie International Edition, 2016, 55(18): 5394-5399. TOTH L.P., GERSBACH C.A., 691. A Light-Inducible CRISPR/Cas9 System for Control of Endogenous Gene Activation", Molecular Therapy, 2015, 23: S275. ЧАЛИСОВА Н.И. и др. "Регуляторное влияние кодируемых аминокислот на основные клеточные процессы у молодых и старых животных", Успехи геронтологии, 2011, 24(2): 189-197. *
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IL263291B1 (en) 2023-03-01
BR112018074930A2 (pt) 2019-03-12
KR102317622B1 (ko) 2021-10-26
RU2018142174A (ru) 2020-07-10
US20190185832A1 (en) 2019-06-20
AU2017275769A1 (en) 2018-12-20
SG11201810772XA (en) 2018-12-28
CA3025591A1 (en) 2017-12-07
AU2017275769B2 (en) 2023-04-13
CN116064534A (zh) 2023-05-05
US20230313161A1 (en) 2023-10-05
JP2022133441A (ja) 2022-09-13
JP2019517262A (ja) 2019-06-24
KR20190031230A (ko) 2019-03-25
IL263291A (en) 2018-12-31
CN109906271A (zh) 2019-06-18
RU2018142174A3 (enExample) 2020-09-30
IL263291B2 (en) 2023-07-01
WO2017207797A1 (en) 2017-12-07
JP7436145B2 (ja) 2024-02-21

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