RU2767784C2 - АНТИ-GARP-TGF-β-АНТИТЕЛА - Google Patents
АНТИ-GARP-TGF-β-АНТИТЕЛА Download PDFInfo
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- RU2767784C2 RU2767784C2 RU2019140602A RU2019140602A RU2767784C2 RU 2767784 C2 RU2767784 C2 RU 2767784C2 RU 2019140602 A RU2019140602 A RU 2019140602A RU 2019140602 A RU2019140602 A RU 2019140602A RU 2767784 C2 RU2767784 C2 RU 2767784C2
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- tgf
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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| AU2002362197A1 (en) * | 2001-12-28 | 2003-07-24 | Chugai Seiyaku Kabushiki Kaisha | Method of stabilizing protein |
| WO2017173091A1 (en) * | 2016-03-30 | 2017-10-05 | Musc Foundation For Research Development | Methods for treatment and diagnosis of cancer by targeting glycoprotein a repetitions predominant (garp) and for providing effective immunotherapy alone or in combination |
| TWI737469B (zh) | 2019-08-28 | 2021-08-21 | 日商中外製藥股份有限公司 | 跨物種抗潛伏性TGF-β1抗體及使用方法 |
| WO2021079958A1 (ja) | 2019-10-25 | 2021-04-29 | 第一三共株式会社 | 抗ｇａｒｐ抗体と免疫調節剤の組み合わせ |
| CN115243724A (zh) | 2020-02-19 | 2022-10-25 | 纳米医疗有限公司 | 可用于治疗癌症的经调配和/或共调配的含有TFGβ拮抗剂前药的脂质体组合物和其方法 |
| US20230192867A1 (en) * | 2020-05-15 | 2023-06-22 | Bristol-Myers Squibb Company | Antibodies to garp |
| CA3198003A1 (en) * | 2020-12-02 | 2022-06-09 | Jiin-Tarng WANG | Anti-garp/tgf? antibodies and methods of use |
| TW202241955A (zh) * | 2021-01-18 | 2022-11-01 | 大陸商上海濟煜醫藥科技有限公司 | Ｇａｒｐ蛋白抗體及其應用 |
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| WO2024018046A1 (en) | 2022-07-22 | 2024-01-25 | Institut National de la Santé et de la Recherche Médicale | Garp as a biomarker and biotarget in t-cell malignancies |
| US20240042020A1 (en) | 2022-07-29 | 2024-02-08 | Abbvie Biotherapeutics Inc. | Anti-garp-tgf-beta1/pd-1 combination therapy |
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| RU2455358C2 (ru) * | 2003-08-22 | 2012-07-10 | Проекто Де Биомедисина Сима, С.Л. | ПРИМЕНЕНИЕ ПОСЛЕДОВАТЕЛЬНОСТИ ДНК, КОТОРАЯ КОДИРУЕТ ПЕПТИД, СПОСОБНЫЙ СВЯЗЫВАТЬСЯ С ТРАНСФОРМИРУЮЩИМ ФАКТОРОМ РОСТА β1 (ВАРИАНТЫ) |
| WO2015015003A1 (en) * | 2013-08-01 | 2015-02-05 | Université Catholique de Louvain | Anti-garp protein and uses thereof |
| WO2016125017A1 (en) * | 2015-02-03 | 2016-08-11 | Universite Catholique De Louvain | Anti-garp protein and uses thereof |
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| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5892019A (en) | 1987-07-15 | 1999-04-06 | The United States Of America, As Represented By The Department Of Health And Human Services | Production of a single-gene-encoded immunoglobulin |
| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| US6673986B1 (en) | 1990-01-12 | 2004-01-06 | Abgenix, Inc. | Generation of xenogeneic antibodies |
| CA2122732C (en) | 1991-11-25 | 2008-04-08 | Marc D. Whitlow | Multivalent antigen-binding proteins |
| NZ298145A (en) | 1994-12-29 | 1998-08-26 | Yamanouchi Pharma Co Ltd | Monoclonal antibodies having inhibitory effect on type ii phospholipase a2, proteins forming part thereof, cells producing them, dna encoding them, recombinant vector comprising the dna and medicament |
| US7709610B2 (en) | 2003-05-08 | 2010-05-04 | Facet Biotech Corporation | Therapeutic use of anti-CS1 antibodies |
| US20070048785A1 (en) | 2004-06-09 | 2007-03-01 | Lin Laura L | Anti-IL-13 antibodies and complexes |
| US8815526B2 (en) | 2005-03-31 | 2014-08-26 | Case Western Reserve University | Methods and reagents for identifying/isolating T regulatory (Treg) cells and for treating individuals |
| EP2001509A1 (en) | 2006-04-03 | 2008-12-17 | Medizinische Hochschule Hannover | Pharmaceuticals for influencing the reaction of the human immune system |
| WO2009073163A1 (en) | 2007-12-03 | 2009-06-11 | American Type Culture Collection (Atcc) | Avian influenza antibodies, compositions, and methods thereof |
| GB2461546B (en) | 2008-07-02 | 2010-07-07 | Argen X Bv | Antigen binding polypeptides |
| WO2010022341A1 (en) | 2008-08-21 | 2010-02-25 | The United State Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of enriching and using regulatory t cells |
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2017
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