RU2751319C2 - Полиморфная форма [5-фтор-3-({ 2-[(4-фторбензол) сульфонил]пиридин-3-ил} метил)-2-метилиндол-1-ил]-уксусной кислоты - Google Patents
Полиморфная форма [5-фтор-3-({ 2-[(4-фторбензол) сульфонил]пиридин-3-ил} метил)-2-метилиндол-1-ил]-уксусной кислоты Download PDFInfo
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- RU2751319C2 RU2751319C2 RU2016141463A RU2016141463A RU2751319C2 RU 2751319 C2 RU2751319 C2 RU 2751319C2 RU 2016141463 A RU2016141463 A RU 2016141463A RU 2016141463 A RU2016141463 A RU 2016141463A RU 2751319 C2 RU2751319 C2 RU 2751319C2
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- compound
- methyl
- polymorphic form
- acetonitrile
- sulfonyl
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| EP0054417A1 (en) * | 1980-12-15 | 1982-06-23 | Pfizer Limited | Indole thromboxane synthetase inhibitors, processes for their preparation, and pharmaceutical compositions containing them |
| WO2006095183A1 (en) * | 2005-03-11 | 2006-09-14 | Oxagen Limited | 1-acetic acid-indole derivatives with pgd2 antagonist activity |
| RU2503672C2 (ru) * | 2008-01-18 | 2014-01-10 | Оксаген Лимитед | Соединения, обладающие активностью антагонистов crth2 |
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| BE790679A (fr) | 1971-11-03 | 1973-04-27 | Ici Ltd | Derives de l'indole |
| DK151884C (da) | 1979-03-07 | 1988-06-13 | Pfizer | Analogifremgangsmaade til fremstilling af 3-(1-imidazolylalkyl)indolderivater eller farmaceutisk acceptable syreadditionssalte deraf |
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| DE3514696A1 (de) | 1985-04-24 | 1986-11-06 | Bayer Ag, 5090 Leverkusen | N-indolylethyl-sulfonsaeureamide, verfahren zu ihrer herstellung und ihre verwendung |
| US5214059A (en) | 1989-07-03 | 1993-05-25 | Hoechst-Roussel Pharmaceuticals Incorporated | 2-(aminoaryl) indoles and indolines as topical antiinflammatory agents for the treatment of skin disorders |
| GB9122590D0 (en) | 1991-10-24 | 1991-12-04 | Lilly Industries Ltd | Pharmaceutical compounds |
| CA2135160A1 (en) | 1992-05-08 | 1993-11-25 | Masatoshi Inai | Indole derivative |
| IL109309A (en) | 1993-04-16 | 2000-06-29 | Lilly Co Eli | 1-H-indole-3-acetic acid hydrazide SPLA2 inhibitors and pharmaceutical compositions containing them |
| GB9317764D0 (en) | 1993-08-26 | 1993-10-13 | Pfizer Ltd | Therapeutic compound |
| US5641800A (en) | 1994-07-21 | 1997-06-24 | Eli Lilly And Company | 1H-indole-1-functional sPLA2 inhibitors |
| US5532237A (en) | 1995-02-15 | 1996-07-02 | Merck Frosst Canada, Inc. | Indole derivatives with affinity for the cannabinoid receptor |
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| ES2262072T3 (es) | 1998-04-28 | 2006-11-16 | Elbion Ag | Derivados de indol y su utilizacion como inhibidores de la fosfodiesterasa 4. |
| EP0984012A3 (en) | 1998-08-31 | 2001-01-10 | Pfizer Products Inc. | Nitric oxide releasing oxindole prodrugs with analgesic and anti-inflammatory properties |
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| SE0200411D0 (sv) | 2002-02-05 | 2002-02-05 | Astrazeneca Ab | Novel use |
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| SE0202241D0 (sv) | 2002-07-17 | 2002-07-17 | Astrazeneca Ab | Novel Compounds |
| DK1569899T3 (da) | 2002-12-10 | 2006-10-23 | Wyeth Corp | Substituerede 3-alkyl- og 3-arylalkyl-1H-indol-1-yl-eddikesyrederivater som inhibitorer af plasminogenaktivator-inhibitor-1 (PAI-1) |
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| SE0302232D0 (sv) | 2003-08-18 | 2003-08-18 | Astrazeneca Ab | Novel Compounds |
| JP2007508363A (ja) | 2003-10-14 | 2007-04-05 | オキサジェン リミテッド | Ｃｒｔｈ２アンタゴニスト活性を有する化合物 |
| GB0324763D0 (en) | 2003-10-23 | 2003-11-26 | Oxagen Ltd | Use of compounds in therapy |
| RU2367659C2 (ru) | 2003-11-05 | 2009-09-20 | Ф.Хоффманн-Ля Рош Аг | Гетероарильные производные в качестве активаторов рецепторов, активируемых пролифераторами пероксисом (ppar) |
| SE0303180D0 (sv) | 2003-11-26 | 2003-11-26 | Astrazeneca Ab | Novel compounds |
| BRPI0510043A (pt) | 2004-04-20 | 2007-10-16 | Pfizer | método de tratamento de dor neuropática usando antagonista de receptor crth2 |
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| GB0412914D0 (en) | 2004-06-10 | 2004-07-14 | Oxagen Ltd | Compounds |
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| GB2422829A (en) | 2005-02-04 | 2006-08-09 | Oxagen Ltd | Pyrrolopyridines and their use in the treatment of diseases mediated by PGD2 at the CRTH2 receptor |
| GB0504150D0 (en) | 2005-03-01 | 2005-04-06 | Oxagen Ltd | Microcrystalline material |
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| US7696222B2 (en) | 2005-08-12 | 2010-04-13 | Merck Frosst Canada Ltd | Indole derivatives as CRTH2 receptor antagonists |
| GB0518783D0 (en) | 2005-09-14 | 2005-10-26 | Argenta Discovery Ltd | Indolizine compounds |
| GB0605743D0 (en) | 2006-03-22 | 2006-05-03 | Oxagen Ltd | Salts with CRTH2 antagonist activity |
| GB0614068D0 (en) | 2006-07-14 | 2006-08-23 | Glaxo Group Ltd | Compounds |
| GB0614066D0 (en) | 2006-07-14 | 2006-08-23 | Glaxo Group Ltd | Compounds |
| CA2658496A1 (en) | 2006-07-22 | 2008-01-31 | Oxagen Limited | 2-{5-fluoro-2-methyl-3-[2-(phenylsulfonyl)benzyl]-1h-indol-yl} acetic acid derivatives and esters thereof having crth2 antagonist activity |
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| EP2265581A1 (en) | 2008-01-22 | 2010-12-29 | Oxagen Limited | Compounds having crth2 antagonist activity |
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| GB201103837D0 (en) | 2011-03-07 | 2011-04-20 | Oxagen Ltd | Amorphous (5-Fluoro-2-Methyl-3-Quinolin-2-Ylmethyl-Indol-1-Yl)-acetic acid |
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| GB201407820D0 (en) * | 2014-05-02 | 2014-06-18 | Atopix Therapeutics Ltd | Polymorphic form |
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2014
- 2014-05-02 GB GBGB1407807.5A patent/GB201407807D0/en not_active Ceased
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2015
- 2015-05-01 EP EP15721029.5A patent/EP3137452B1/en active Active
- 2015-05-01 RU RU2016141463A patent/RU2751319C2/ru active
- 2015-05-01 JP JP2016565467A patent/JP2017514842A/ja active Pending
- 2015-05-01 WO PCT/GB2015/051289 patent/WO2015166274A1/en not_active Ceased
- 2015-05-01 US US15/308,288 patent/US10011584B2/en active Active
- 2015-05-01 UA UAA201611544A patent/UA121473C2/uk unknown
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Also Published As
| Publication number | Publication date |
|---|---|
| UA121473C2 (uk) | 2020-06-10 |
| WO2015166274A1 (en) | 2015-11-05 |
| US10011584B2 (en) | 2018-07-03 |
| RU2016141463A3 (enExample) | 2018-11-06 |
| EP3137452A1 (en) | 2017-03-08 |
| GB201407807D0 (en) | 2014-06-18 |
| US20170057944A1 (en) | 2017-03-02 |
| JP2017514842A (ja) | 2017-06-08 |
| RU2016141463A (ru) | 2018-06-05 |
| EP3137452B1 (en) | 2019-12-25 |
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