RU2720984C2 - Терапевтические композиции и способы применения для лечения рака - Google Patents

Терапевтические композиции и способы применения для лечения рака Download PDF

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RU2720984C2
RU2720984C2 RU2017134519A RU2017134519A RU2720984C2 RU 2720984 C2 RU2720984 C2 RU 2720984C2 RU 2017134519 A RU2017134519 A RU 2017134519A RU 2017134519 A RU2017134519 A RU 2017134519A RU 2720984 C2 RU2720984 C2 RU 2720984C2
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cells
virus
cancer
tumor
alpha
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Ури ГАЛИЛИ
Майкл ВЕСТБИ
Стивен ШО
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Агалиммьюн Лимитед
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
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    • C12Y204/01—Hexosyltransferases (2.4.1)
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    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
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    • C12Y204/00—Glycosyltransferases (2.4)
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RU2017134519A 2015-04-07 2016-04-07 Терапевтические композиции и способы применения для лечения рака RU2720984C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1505860.5 2015-04-07
GBGB1505860.5A GB201505860D0 (en) 2015-04-07 2015-04-07 Therapeutic compositions and methods of use for treating cancer
PCT/GB2016/050973 WO2016162675A1 (en) 2015-04-07 2016-04-07 Therapeutic compositions and methods of use for treating cancer

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RU2017134519A RU2017134519A (ru) 2019-04-04
RU2017134519A3 RU2017134519A3 (cg-RX-API-DMAC10.html) 2019-10-10
RU2720984C2 true RU2720984C2 (ru) 2020-05-15

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US (2) US20180104288A1 (cg-RX-API-DMAC10.html)
EP (1) EP3280798B1 (cg-RX-API-DMAC10.html)
JP (2) JP2018512150A (cg-RX-API-DMAC10.html)
KR (1) KR102544032B1 (cg-RX-API-DMAC10.html)
CN (1) CN107787364A (cg-RX-API-DMAC10.html)
BR (1) BR112017021700A2 (cg-RX-API-DMAC10.html)
CA (1) CA2981925C (cg-RX-API-DMAC10.html)
ES (1) ES2743952T3 (cg-RX-API-DMAC10.html)
GB (1) GB201505860D0 (cg-RX-API-DMAC10.html)
HK (1) HK1251009B (cg-RX-API-DMAC10.html)
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SG11201507393TA (en) 2013-03-14 2015-10-29 Salk Inst For Biological Studi Oncolytic adenovirus compositions
ES2899913T3 (es) 2014-09-24 2022-03-15 Salk Inst For Biological Studi Virus tumorales oncolíticos y métodos de uso
WO2017147265A1 (en) 2016-02-23 2017-08-31 Salk Institute For Biological Studies High throughput assay for measuring adenovirus replication kinetics
EP3390645B1 (en) 2016-02-23 2022-09-14 Salk Institute for Biological Studies Exogenous gene expression in therapeutic adenovirus for minimal impact on viral kinetics
AU2017375633C1 (en) 2016-12-12 2023-04-27 Salk Institute For Biological Studies Tumor-targeting synthetic adenoviruses and uses thereof
BR112020019942A2 (pt) 2018-04-09 2021-01-26 Salk Institute For Biological Studies composições de adenovírus oncolítico com propriedades de replicação aprimoradas
CN110856724B (zh) * 2018-08-24 2022-05-27 杭州康万达医药科技有限公司 包含核酸及car修饰的免疫细胞的治疗剂及其应用
EP3970754A4 (en) * 2019-05-14 2023-08-02 Oncolys BioPharma, Inc. METHOD OF ADMINISTRATION OF ONCOLYTIC VIRUS TO TUMOR TISSUE AND DEVICE FOR ADMINISTRATION
CN115103905B (zh) * 2020-01-10 2025-02-21 香港大学 表达α-1,3-半乳糖基转移酶的重组病毒及其用途
PH12023551419A1 (en) * 2020-11-30 2024-01-29 Univ Cornell Cancer immunotherapies to promote hyperacute rejection
CN112941039A (zh) * 2021-02-01 2021-06-11 南京大学 一种新型类囊泡溶瘤病毒及其在制备抗肿瘤药物上的应用
WO2026068773A1 (en) * 2024-09-27 2026-04-02 Repudio Ab Immunotherapy using ggta and nap

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US20030186850A1 (en) * 2000-05-11 2003-10-02 Glycozym Aps Methods of modulating functions of polypeptide GalNAc-transferases and of screening test substances to find agents herefor, pharmaceutical compositions comprising such agents and the use of such agents for preparing medicaments
US20050201993A1 (en) * 2002-10-09 2005-09-15 Link Charles J.Jr. Antitumor vaccination using allogeneic tumor cells expressing alpha (1,3)-galactosyltransferase
EA013615B1 (ru) * 2004-11-12 2010-06-30 Байер Шеринг Фарма Акциенгезельшафт Рекомбинантный онколитический парамиксовирус и его применение
WO2014089558A1 (en) * 2012-12-07 2014-06-12 North Carolina State University Beta-hexosyl-transferases and uses thereof
RU2536931C2 (ru) * 2009-05-06 2014-12-27 Фундасио Институт Д`Инвестигасио Биомедика Де Бельвитге (Идибель) Онколитический аденовирус для лечения рака, его применение и фармацевтическая композиция, содержащая его

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GB9810904D0 (en) 1998-05-20 1998-07-22 Univ London Mutant herpes simplex viruses and uses thereof
JP4810042B2 (ja) 2000-01-21 2011-11-09 バイオヴェックス リミテッド ヘルペスウイルス株
WO2002042468A2 (en) 2000-11-27 2002-05-30 Geron Corporation Glycosyltransferase vectors for treating cancer
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US7820628B2 (en) 2005-02-22 2010-10-26 University Of Massachusetts Medical School Tumor lesion regression and conversion in situ into autologous tumor vaccines by compositions that result in anti-Gal antibody binding
EP2085092A1 (en) * 2008-01-29 2009-08-05 Bayer Schering Pharma Aktiengesellschaft Attenuated oncolytic paramyxoviruses encoding avian cytokines
EP2697368B1 (en) * 2011-04-15 2019-06-05 Genelux Corporation Clonal strains of attenuated vaccinia viruses and methods of use thereof
CN105779397B (zh) * 2014-12-22 2019-07-19 彭霞 溶瘤异源重组新城疫病毒及其制备方法与应用

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Publication number Priority date Publication date Assignee Title
US20030186850A1 (en) * 2000-05-11 2003-10-02 Glycozym Aps Methods of modulating functions of polypeptide GalNAc-transferases and of screening test substances to find agents herefor, pharmaceutical compositions comprising such agents and the use of such agents for preparing medicaments
US20050201993A1 (en) * 2002-10-09 2005-09-15 Link Charles J.Jr. Antitumor vaccination using allogeneic tumor cells expressing alpha (1,3)-galactosyltransferase
EA013615B1 (ru) * 2004-11-12 2010-06-30 Байер Шеринг Фарма Акциенгезельшафт Рекомбинантный онколитический парамиксовирус и его применение
RU2536931C2 (ru) * 2009-05-06 2014-12-27 Фундасио Институт Д`Инвестигасио Биомедика Де Бельвитге (Идибель) Онколитический аденовирус для лечения рака, его применение и фармацевтическая композиция, содержащая его
WO2014089558A1 (en) * 2012-12-07 2014-06-12 North Carolina State University Beta-hexosyl-transferases and uses thereof

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WO2016162675A1 (en) 2016-10-13
RU2017134519A3 (cg-RX-API-DMAC10.html) 2019-10-10
ES2743952T3 (es) 2020-02-21
JP7066812B2 (ja) 2022-05-13
IL254842B (en) 2022-01-01
JP2021045152A (ja) 2021-03-25
KR102544032B1 (ko) 2023-06-14
EP3280798B1 (en) 2019-06-19
JP2018512150A (ja) 2018-05-17
IL254842A0 (en) 2017-12-31
EP3280798A1 (en) 2018-02-14
CN107787364A (zh) 2018-03-09
RU2017134519A (ru) 2019-04-04
BR112017021700A2 (pt) 2018-07-24
KR20180015113A (ko) 2018-02-12
HK1251009B (en) 2020-06-26
US12023362B2 (en) 2024-07-02
US20180104288A1 (en) 2018-04-19
MX377211B (es) 2025-03-07
US20200155626A1 (en) 2020-05-21
GB201505860D0 (en) 2015-05-20
CA2981925C (en) 2025-03-11
MX2017012867A (es) 2018-05-11
CA2981925A1 (en) 2016-10-13

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