RU2717454C2 - Антисмысловые олигонуклеотиды в качестве ингибиторов сигнального пути tgf-r - Google Patents

Антисмысловые олигонуклеотиды в качестве ингибиторов сигнального пути tgf-r Download PDF

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RU2717454C2
RU2717454C2 RU2017120481A RU2017120481A RU2717454C2 RU 2717454 C2 RU2717454 C2 RU 2717454C2 RU 2017120481 A RU2017120481 A RU 2017120481A RU 2017120481 A RU2017120481 A RU 2017120481A RU 2717454 C2 RU2717454 C2 RU 2717454C2
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sgb
stb
sab
seq
lna
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RU2017120481A3 (fr
RU2017120481A (ru
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Маркус Хоссбах
Моника КРАМПЕРТ
Ханс-Лотар АРТ
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Ньюровижн Фарма Гмбх
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RU2017120481A 2014-11-16 2015-11-16 Антисмысловые олигонуклеотиды в качестве ингибиторов сигнального пути tgf-r RU2717454C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14193368.9A EP3020813A1 (fr) 2014-11-16 2014-11-16 Oligonculéotides antisens en tant qu'inhibiteurs de la signalisation de TGF-R
EP14193368.9 2014-11-16
PCT/EP2015/076730 WO2016075339A1 (fr) 2014-11-16 2015-11-16 Oligonucléotides antisens à titre d'inhibiteurs de la signalisation du tgf-r

Publications (3)

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RU2017120481A RU2017120481A (ru) 2018-12-18
RU2017120481A3 RU2017120481A3 (fr) 2019-05-27
RU2717454C2 true RU2717454C2 (ru) 2020-03-23

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US (4) US10363266B2 (fr)
EP (3) EP3020813A1 (fr)
JP (2) JP6832285B2 (fr)
KR (2) KR102417601B1 (fr)
CN (2) CN113151261A (fr)
AU (3) AU2015345006B2 (fr)
BR (1) BR112017006201B1 (fr)
CA (2) CA3201845C (fr)
CL (2) CL2017001233A1 (fr)
CY (1) CY1121110T1 (fr)
DK (1) DK3218488T3 (fr)
ES (1) ES2705066T3 (fr)
HU (1) HUE041793T2 (fr)
IL (2) IL251565B (fr)
MX (2) MX2017006369A (fr)
MY (1) MY181404A (fr)
PL (1) PL3218488T3 (fr)
PT (1) PT3218488T (fr)
RU (1) RU2717454C2 (fr)
SG (1) SG11201703127SA (fr)
TR (1) TR201900844T4 (fr)
WO (1) WO2016075339A1 (fr)

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EP3020813A1 (fr) * 2014-11-16 2016-05-18 Neurovision Pharma GmbH Oligonculéotides antisens en tant qu'inhibiteurs de la signalisation de TGF-R
WO2019010226A1 (fr) * 2017-07-03 2019-01-10 The Regents Of The University Of California Microarn-214 antisens chimiquement modifié et son utilisation pour le traitement de la rectocolite hémorragique et de la proctite
MX2020006430A (es) * 2017-12-22 2020-09-17 Roche Innovation Ct Copenhagen As Oligonucleotidos que comprenden un enlace internucleosidico de fosforoditioato.
WO2019122277A1 (fr) * 2017-12-22 2019-06-27 Roche Innovation Center Copenhagen A/S Nouvelles thiophosphoramidites
TW201934750A (zh) * 2017-12-22 2019-09-01 丹麥商羅氏創新中心哥本哈根有限公司 包含二硫代磷酸酯核苷間連結之間隙子(gapmer)寡核苷酸
JP2023548597A (ja) * 2020-10-29 2023-11-17 エー. ガルシア-ブランコ,マリアーノ がんを処置するための可溶性インターロイキン-7受容体(sIL7R)変調療法
CN114588160A (zh) * 2020-12-07 2022-06-07 四川大学华西医院 具有抗肺纤维化作用的次黄碱衍生物
CN113992687B (zh) * 2021-12-28 2022-04-08 浙江宇视科技有限公司 智能业务集群调度方法、装置、电子设备及存储介质

Citations (1)

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RU2385933C2 (ru) * 2004-02-09 2010-04-10 Реженьон Гмбх Ингибиторы передачи сигнала трансформирующих факторов роста (tgf-r) для лечения расстройств цнс

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EP0885016B1 (fr) 1996-02-19 2003-04-16 Amersham Health AS Milieu de contraste stabilise thermiquement
US20030064944A1 (en) 2001-06-21 2003-04-03 Isis Pharmaceuticals Inc. Antisense modulation of transforming growth factor beta receptor II expression
EP2141233B1 (fr) 2002-11-18 2016-10-19 Roche Innovation Center Copenhagen A/S Conception antisens
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