RU2708246C2 - Комбинации лекарственных средств - Google Patents
Комбинации лекарственных средств Download PDFInfo
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- RU2708246C2 RU2708246C2 RU2015141628A RU2015141628A RU2708246C2 RU 2708246 C2 RU2708246 C2 RU 2708246C2 RU 2015141628 A RU2015141628 A RU 2015141628A RU 2015141628 A RU2015141628 A RU 2015141628A RU 2708246 C2 RU2708246 C2 RU 2708246C2
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Landscapes
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| US7700567B2 (en) | 2005-09-29 | 2010-04-20 | Supergen, Inc. | Oligonucleotide analogues incorporating 5-aza-cytosine therein |
| EP2750768B1 (en) | 2011-08-30 | 2018-10-03 | Astex Pharmaceuticals, Inc. | Decitabine derivative formulations |
| US10519237B2 (en) | 2014-03-12 | 2019-12-31 | Yeda Research And Development Co. Ltd | Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS |
| US9394365B1 (en) | 2014-03-12 | 2016-07-19 | Yeda Research And Development Co., Ltd | Reducing systemic regulatory T cell levels or activity for treatment of alzheimer's disease |
| US10618963B2 (en) | 2014-03-12 | 2020-04-14 | Yeda Research And Development Co. Ltd | Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS |
| BR112016020919A2 (pt) | 2014-03-12 | 2018-01-23 | Yeda Res & Dev | redução dos níveis ou da atividade sistêmica de células t regulatórias para o tratamento de doença e lesão do snc |
| CA2947471A1 (en) * | 2014-05-13 | 2015-11-19 | Medimmune Limited | Anti-b7-h1 and anti-ctla-4 antibodies for treating non-small cell lung cancer |
| CN107072984B (zh) * | 2014-07-15 | 2021-10-01 | 约翰·霍普金斯大学 | 源自骨髓的抑制细胞的抑制和免疫检查点阻断 |
| CA3116265A1 (en) | 2014-10-07 | 2016-04-14 | Cytlimic Inc. | Hsp70-derived peptide, pharmaceutical composition for treating or preventing cancer using same, immunity inducer, and method for producing antigen-presenting cell |
| WO2016061231A1 (en) * | 2014-10-14 | 2016-04-21 | Deciphera Pharmaceuticals, Llc | Inhibition of tumor cell interactions with the microenvironment resulting in a reduction in tumor growth and disease progression |
| WO2016100851A1 (en) | 2014-12-18 | 2016-06-23 | Lankenau Institute For Medical Research | Methods and compositions for the treatment of retinopathy and other ocular diseases |
| MA41463A (fr) | 2015-02-03 | 2017-12-12 | Anaptysbio Inc | Anticorps dirigés contre le gène d'activation 3 des lymphocytes (lag-3) |
| JP6898225B2 (ja) | 2015-03-09 | 2021-07-07 | サイトリミック株式会社 | Ｇｐｃ３由来のペプチド、これを用いた癌の治療又は予防のための医薬組成物、免疫誘導剤、及び抗原提示細胞の製造方法 |
| RU2709015C2 (ru) | 2015-04-07 | 2019-12-13 | Ситлимик Инк. | Лекарственное средство |
| KR20180024010A (ko) * | 2015-07-02 | 2018-03-07 | 오쓰까 세이야꾸 가부시키가이샤 | 동결건조된 약제학적 조성물 |
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| GB201704966D0 (en) | 2017-03-28 | 2017-05-10 | Astex Therapeutics Ltd | Pharmaceutical compounds |
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| EP3661522A2 (en) | 2017-08-03 | 2020-06-10 | Otsuka Pharmaceutical Co., Ltd. | Drug compound and purification methods thereof |
| WO2019126257A1 (en) * | 2017-12-21 | 2019-06-27 | Merck Patent Gmbh | Combination of an anti-pd-l1 antibody and ido1 inhibitor for the treatment of cancer |
| CN108948203B (zh) * | 2018-08-09 | 2019-06-04 | 南京鼓楼医院 | 抗pd-1单克隆抗体及其制备方法和应用 |
| EP3725370A1 (en) | 2019-04-19 | 2020-10-21 | ImmunoBrain Checkpoint, Inc. | Modified anti-pd-l1 antibodies and methods and uses for treating a neurodegenerative disease |
| PH12022552820A1 (en) * | 2020-04-24 | 2024-03-25 | Genexine Inc | Method for treating cervical cancer |
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| US20050266012A1 (en) * | 2004-05-26 | 2005-12-01 | Jean-Marie Andrieu | Compositions comprising demethylating agents as enhancers of immunotherapy for the treatment of chronic infections and neoplastic diseases and methods for treating the same |
| US7700567B2 (en) * | 2005-09-29 | 2010-04-20 | Supergen, Inc. | Oligonucleotide analogues incorporating 5-aza-cytosine therein |
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| BR9907691B1 (pt) | 1998-02-05 | 2011-05-31 | derivado de antìgeno e antìgeno da famìlia mage associado a tumor, seqüência de ácido nucléico, codificando os mesmos, seus usos na preparação de vacina, processo para produção de vacina e vacina. | |
| SG143018A1 (en) | 1998-12-23 | 2008-06-27 | Pfizer | Human monoclonal antibodies to ctla-4 |
| GB9908885D0 (en) * | 1999-04-19 | 1999-06-16 | Smithkline Beecham Biolog | Vccine |
| CA2370697C (en) * | 1999-04-19 | 2012-03-06 | Smithkline Beecham Biologicals S.A. | Adjuvant composition comprising saponin and an immunostimulatory oligonucleotide |
| KR20020047132A (ko) | 1999-08-24 | 2002-06-21 | 메다렉스, 인코포레이티드 | 인간 씨티엘에이-4 항체 및 그의 용도 |
| US6613753B2 (en) * | 2001-02-21 | 2003-09-02 | Supergen, Inc. | Restore cancer-suppressing functions to neoplastic cells through DNA hypomethylation |
| US20030148973A1 (en) | 2001-05-23 | 2003-08-07 | Peter Emtage | MAGE-A1 peptides for treating or preventing cancer |
| CA2489076A1 (en) * | 2002-06-10 | 2003-12-18 | Avax Technologies Inc. | Cryopreservation of haptenized tumor cells |
| WO2005033278A2 (en) | 2003-09-30 | 2005-04-14 | Ludwig Institute For Cancer Research | In vivo efficacy of ny-eso-1 plus iscom |
| BRPI0515735A2 (pt) | 2004-11-04 | 2011-10-11 | Pfizer Prod Inc | tratamento de combinação de anticorpo de ctla4 e inibidor de aromatase para cáncer de mama, suas composições farmacêuticas e respectivos usos |
| AU2005321898B2 (en) | 2004-12-29 | 2012-07-19 | Mannkind Corporation | Use of compositions comprising various tumor-associated antigens as anti-cancer vaccines |
| JP2008526976A (ja) * | 2005-01-14 | 2008-07-24 | アバクス・テクノロジーズ・インコーポレーテッド | 癌治療用ワクチンの製造方法 |
| EP2161336B2 (en) | 2005-05-09 | 2017-03-29 | ONO Pharmaceutical Co., Ltd. | Human monoclonal antibodies to programmed death 1(PD-1) and methods for treating cancer using anti-PD-1 antibodies alone or in combination with other immunotherapeutics |
| AU2006265108C1 (en) | 2005-07-01 | 2013-01-17 | E. R. Squibb & Sons, L.L.C. | Human monoclonal antibodies to programmed death ligand 1 (PD-L1) |
| EP1928492B1 (en) * | 2005-09-01 | 2011-02-23 | Celgene Corporation | Immunological uses of immunodulatory compounds for vaccine and anti-infections disease therapy |
| US9744183B2 (en) * | 2009-07-06 | 2017-08-29 | Wave Life Sciences Ltd. | Nucleic acid prodrugs and methods of use thereof |
| SMT201700293T1 (it) * | 2009-07-20 | 2017-07-18 | Bristol Myers Squibb Co | Combinazione di un anticorpo anti-ctla-4 con etoposide per il trattamento sinergico di malattie proliferative |
| US20120277158A1 (en) * | 2009-10-06 | 2012-11-01 | Angiochem Inc. | Compositions and methods for the transport of therapeutic agents |
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| EP2958571B1 (en) * | 2013-02-21 | 2024-04-10 | Michele Maio | Dna hypomethylating agents for cancer therapy |
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- 2015-08-28 PH PH12015501905A patent/PH12015501905A1/en unknown
- 2015-08-30 SA SA515360959A patent/SA515360959B1/ar unknown
-
2019
- 2019-04-12 JP JP2019076111A patent/JP2019142911A/ja active Pending
- 2019-07-10 CY CY20191100738T patent/CY1122554T1/el unknown
- 2019-07-17 US US16/514,377 patent/US20200009247A1/en not_active Abandoned
- 2019-08-16 ZA ZA2019/05426A patent/ZA201905426B/en unknown
- 2019-10-17 PH PH12019550222A patent/PH12019550222A1/en unknown
-
2020
- 2020-09-15 IL IL277385A patent/IL277385A/en unknown
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| US20050266012A1 (en) * | 2004-05-26 | 2005-12-01 | Jean-Marie Andrieu | Compositions comprising demethylating agents as enhancers of immunotherapy for the treatment of chronic infections and neoplastic diseases and methods for treating the same |
| US7700567B2 (en) * | 2005-09-29 | 2010-04-20 | Supergen, Inc. | Oligonucleotide analogues incorporating 5-aza-cytosine therein |
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| SANDRA C. ET AL, Immunomodulatory activity of SGI-110, a 5-aza-2'-deoxycytidine-containing demethylating dinucleotide, Cancer immunology, immunotherapy, 2012, vol. 62, no. 3, pages 605 - 614 -реферат * |
| STEVEN J. ET AL. Targeting cytotoxic T-lymphocyte antigen-4 (CTLA-4), Cancer, 2007, vol. 110, no. 12, doi:10.1002/cncr.23086, pages 2614 - 2627. * |
| STEVEN J. ET AL. Targeting cytotoxic T-lymphocyte antigen-4 (CTLA-4), Cancer, 2007, vol. 110, no. 12, doi:10.1002/cncr.23086, pages 2614 - 2627. SANDRA C. ET AL, Immunomodulatory activity of SGI-110, a 5-aza-2'-deoxycytidine-containing demethylating dinucleotide, Cancer immunology, immunotherapy, 2012, vol. 62, no. 3, pages 605 - 614 -реферат. * |
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