RU2692243C1 - Применение лактитола и пероральная лекарственная форма для лечения и профилактики неалкогольной жировой болезни печени - Google Patents
Применение лактитола и пероральная лекарственная форма для лечения и профилактики неалкогольной жировой болезни печени Download PDFInfo
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- RU2692243C1 RU2692243C1 RU2018111985A RU2018111985A RU2692243C1 RU 2692243 C1 RU2692243 C1 RU 2692243C1 RU 2018111985 A RU2018111985 A RU 2018111985A RU 2018111985 A RU2018111985 A RU 2018111985A RU 2692243 C1 RU2692243 C1 RU 2692243C1
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- lactitol
- liver
- liver disease
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- alcoholic fatty
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- 230000002401 inhibitory effect Effects 0.000 description 1
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- 230000000968 intestinal effect Effects 0.000 description 1
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- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 229940039696 lactobacillus Drugs 0.000 description 1
- 229940039695 lactobacillus acidophilus Drugs 0.000 description 1
- 229940068140 lactobacillus bifidus Drugs 0.000 description 1
- 229940039781 leptin Drugs 0.000 description 1
- NRYBAZVQPHGZNS-ZSOCWYAHSA-N leptin Chemical compound O=C([C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CC(C)C)CCSC)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CS)C(O)=O NRYBAZVQPHGZNS-ZSOCWYAHSA-N 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
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- 230000007246 mechanism Effects 0.000 description 1
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- 239000000203 mixture Substances 0.000 description 1
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- 210000003205 muscle Anatomy 0.000 description 1
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- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 description 1
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 description 1
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- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
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- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7016—Disaccharides, e.g. lactose, lactulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2018111985A RU2692243C1 (ru) | 2018-04-03 | 2018-04-03 | Применение лактитола и пероральная лекарственная форма для лечения и профилактики неалкогольной жировой болезни печени |
| EA202092349A EA202092349A1 (ru) | 2018-04-03 | 2019-03-13 | Лактитол и пероральная лекарственная форма при неалкогольной жировой болезни печени |
| KR1020207031617A KR102569081B1 (ko) | 2018-04-03 | 2019-03-13 | 락티톨 및 비알코올성 지방간 질병을 위한 경구용 약제학적 형태 |
| PCT/RU2019/000157 WO2019194703A1 (ru) | 2018-04-03 | 2019-03-13 | Лактитол и пероральная лекарственная форма при неалкогольной жировой болезни печени |
| CN201980023588.3A CN111936148B (zh) | 2018-04-03 | 2019-03-13 | 用于非酒精性脂肪肝病的乳糖醇及口服药物剂型 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2018111985A RU2692243C1 (ru) | 2018-04-03 | 2018-04-03 | Применение лактитола и пероральная лекарственная форма для лечения и профилактики неалкогольной жировой болезни печени |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2692243C1 true RU2692243C1 (ru) | 2019-06-24 |
Family
ID=67038280
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2018111985A RU2692243C1 (ru) | 2018-04-03 | 2018-04-03 | Применение лактитола и пероральная лекарственная форма для лечения и профилактики неалкогольной жировой болезни печени |
Country Status (5)
| Country | Link |
|---|---|
| KR (1) | KR102569081B1 (ko) |
| CN (1) | CN111936148B (ko) |
| EA (1) | EA202092349A1 (ko) |
| RU (1) | RU2692243C1 (ko) |
| WO (1) | WO2019194703A1 (ko) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2113998A (en) * | 1982-02-05 | 1983-08-17 | Cv Chemie Combinatie Amsterdam | Lactitol for the treatment of liver disease |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002039832A1 (en) * | 2000-11-17 | 2002-05-23 | Purac Biochem B.V. | Use of lactitol for improving intestinal microflora |
-
2018
- 2018-04-03 RU RU2018111985A patent/RU2692243C1/ru active
-
2019
- 2019-03-13 CN CN201980023588.3A patent/CN111936148B/zh active Active
- 2019-03-13 KR KR1020207031617A patent/KR102569081B1/ko active IP Right Grant
- 2019-03-13 WO PCT/RU2019/000157 patent/WO2019194703A1/ru active Application Filing
- 2019-03-13 EA EA202092349A patent/EA202092349A1/ru unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2113998A (en) * | 1982-02-05 | 1983-08-17 | Cv Chemie Combinatie Amsterdam | Lactitol for the treatment of liver disease |
Non-Patent Citations (4)
| Title |
|---|
| Lanthier P.L. et al. Lactitol in the treatment of chronic hepatic encephalopathy: an open comparison with lactulose / Gut, 1985, V.26, pp.415-420. * |
| Гальченко О.Е. и др. Современные возможности применения гепатопротекторов в лечении хронических диффузных заболеваний печени / Лекарственный вестник, 2015, Т.9, N.2 (58), c.7-17. * |
| Лекарственный препарат "Экспортал" (порошок для приготовления раствора для приема внутрь) / Зарегистрирован в государственном реестре лекарственных средств, регистрационный номер: ЛСР-003898/07, дата регистрации: 19.11.2007. * |
| Лекарственный препарат "Экспортал" (порошок для приготовления раствора для приема внутрь) / Зарегистрирован в государственном реестре лекарственных средств, регистрационный номер: ЛСР-003898/07, дата регистрации: 19.11.2007. Lanthier P.L. et al. Lactitol in the treatment of chronic hepatic encephalopathy: an open comparison with lactulose / Gut, 1985, V.26, pp.415-420. Гальченко О.Е. и др. Современные возможности применения гепатопротекторов в лечении хронических диффузных заболеваний печени / Лекарственный вестник, 2015, Т.9, N.2 (58), c.7-17. * |
Also Published As
| Publication number | Publication date |
|---|---|
| EA202092349A1 (ru) | 2020-12-22 |
| CN111936148B (zh) | 2023-07-14 |
| KR102569081B1 (ko) | 2023-08-23 |
| KR20200140326A (ko) | 2020-12-15 |
| CN111936148A (zh) | 2020-11-13 |
| WO2019194703A1 (ru) | 2019-10-10 |
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