RU2605200C2 - Method of production of fodder additive for farm animals - Google Patents

Abstract

FIELD: agriculture.

SUBSTANCE: invention relates to fodder production. Fodder additive for feeding of any farm animals contains: beta-carotene in gelatine microcapsules, glycinates of zinc, iron, manganese, copper and cobalt, ceoiodine, DAFS-25, ascorbic acid, antioxidants alpha tocopherol acetate, dihydroquercetin, stabilizer butyloxyanisole, gelatin, filler starch. All components are taken at specified weight ratio.

EFFECT: feed additive provides high bioavailability of active ingredients in animals, which is reflected in normalization of metabolism, producing healthy breed, preventing postpartum diseases, increased milk yield, milk fat content, reproductive function.

1 cl, 2 tbl, 4 ex

Description

The invention relates to the field of feeding farm animals. Feed additive "Karovit +" is intended for introduction into the diet of cows and other types of farm animals, it contains in its composition, wt. %: beta-carotene in gelatin microcapsules - 1.0-3.0, zinc glycinates - 0.5-1.5, iron - 0.5-1.8, manganese - 0.3-0.8, copper - 0.01-0.2, cobalt - 0.015-0.025, ceoiod - 0.007-0.02, DAFS-25 - 0.0025-0.007, ascorbic acid - 0.25-0.5, antioxidants alpha-tocopherol acetate - 0 , 5-0.9, dihydroquercetin - 0.2, butyloxyanisole stabilizer - 0.002, gelatin - 10, starch filler - up to 100. Adding a feed additive to the animal’s diet provides effective prevention of metabolic disorders, obtaining a healthy offspring, increases reproductive function, milk yield by 12%, fat content s milk 4.4%, reduces post-partum cows disease by 32%, gastrointestinal disease calves 18.4%. Tab. 2.

The invention relates to the field of feed production, in particular to drugs used for the prevention of metabolic disorders, postpartum diseases in cows, obtaining a healthy offspring, increasing milk productivity, milk fat, reproductive function.

Known dietary supplement based on wt. %: beta-carotene - 1.0-3.0, which also includes alpha-tocopherol acetate - 0.5-0.9, zinc ascorbate - 1.9-2.0 and an emulsifier [2]. The drug provides increased body resistance due to the normalization of the antioxidant buffer system. The disadvantage is the narrow focus of the action.

Known feed vitamin-mineral supplement, which contains 1 kg: calcium gluconate (20%) - 200 g, phosphorus - 20 g, sulfur - 50 g, vitamins B ₁ - 500 mg, B ₄ - 1000 mg, B ₅ - 5000 mg, B ₆ - 650 mg, B _c - 30 mg, B ₁₂ - 15 mg, biotin - 100 mg, vitamin A - 600 tME, vitamin E - 500 mg, methionine - 25 mg, “Selinium 2000” - 10 g, zinc - 6000 mg, copper - 50 mg, cobalt - 50 mg, iodine - 100 mg, magnesium - 30 g, vitamin D - 200 tME [3]. This feed supplement provides a wide range of biologically active substances. The effectiveness of the drug is worsened by the low digestibility of inorganic salts of macro- and microelements and the manifestation of their antagonistic relationships [6].

A known method of producing organic compounds of trace elements of copper, iron, manganese, zinc with a yeast autolysate [4]. The disadvantage of this drug is the absence of other equally important trace elements in the composition, which narrows the spectrum of its action.

The closest in essence to the claimed invention is a feed additive containing the ingredients, wt. %: zinc citrates - 0.13-1.2, iron - 0.1-0.5, manganese - 0.3-0.8, copper - 0.01-0.4, cobalt - 0.01-0.025 potassium iodide - 0.007-0.02, sodium selenite - 0.002-0.005, succinic acid - 0.015-0.04, lysine - 0.3-1.0, methionine - 0.15-0.5, defluorinated phosphate - 1 , 0-2.0, ascorbic acid 0.25-0.5, mycelium citric acid 50.0-76.2 [5]. The composition of the drug contains trace elements in the form of organic compounds, which undoubtedly increases their bioavailability in the animal body. At the same time, potassium iodide is unstable during storage, which shortens the duration of the drug [1]. The inorganic compound sodium selenite is a highly toxic substance and, if the dosage is not correctly calculated, can lead to intoxication phenomena, primarily to liver dystrophy. In the feed additive there is no group of biologically active substances in the form of vitamins, which limits its effectiveness.

The aim of the present invention is to obtain a highly effective wide spectrum of feed additives to normalize metabolic processes in the body of cows, to obtain a healthy offspring, the prevention of postpartum diseases, increase milk productivity, milk fat, reproductive function.

This goal is achieved in that the feed additive "Karovit +", including biologically active substances in the composition, wt. %: zinc glycinates - 0.5-1.5, iron - 0.5-1.8, manganese - 0.3-0.8, copper - 0.01-0.2, cobalt - 0.015-0.025, stabilizer butyloxyanisole - 0.002, according to the invention additionally contains beta-carotene in gelatin microcapsules - 1.0-3.0, ascorbic acid - 0.25-0.5, alpha-tocopherol acetate - 0.5-0.9, dihydroquercetin from larch - 0.2, a stable iodine-containing compound associated with the zeolite - zeoiod - 0.007-0.02, the organic compound of selenium DAFS-25 - 0.0025-0.007.

The essence of the invention lies in the fact that, in contrast to the known analogue in the proposed technical solution, beta-carotene in gelatin microcapsules, ascorbic acid, alpha-tocopherol acetate, dihydroquercytin, zeoiod, DAFS-25 are introduced into the Karovit + preparation during the technological cycle . Thus, the claimed drug meets the criterion of "novelty." In this case, the drug acquires additional new properties that ensure high bioavailability of the active components in the animal’s body, which is reflected in the normalization of metabolism, obtaining a healthy offspring, the prevention of postpartum diseases, increasing milk productivity, milk fat, and reproductive function.

The solution of the problem and the achievement of the technical results of the proposed method became possible due to the fact that, first, beta-carotene microemulsion is obtained, including its homogenization in the molten gelatin inside the reactor when mixed under conditions of + 45-50 ° С with the addition of alpha-tocopherol acetate, ascorbic acid, butyloxyanisole and dehydroquercetin. At the second stage, a filler in the form of starch, an organic solvent and trace elements glycinates, ceoiod, DAFS-25 are added. Stirring is continued for 1 hour under vacuum at 0.1-0.2 atm. Next, drying is carried out for 5 hours to obtain a dry fine powder with a moisture content of 0.3%. The proposed method allows to obtain a water-dispersible form of feed additives.

The claimed invention is illustrated by the following examples.

EXAMPLE 1. Prepare a water-dispersible preparation according to the claimed method with a ratio of components, wt. %: beta-carotene in gelatin microcapsules - 1.0, zinc glycinates - 0.5, iron - 0.5, manganese - 0.3, copper - 0.01, cobalt - 0.015, ceoiod - 0.007, DAFS-25 - 0.0025, vitamin C -0.25, vitamin E 0.5, dihydroquercytin (DHA) 0.2, butyloxyanisole (BOA) 0.002, gelatin 10, chloroform 200% by weight of beta-carotene, starch up to 100. This corresponds to the minimum values of the components within the declared limits. Received a water-dispersible powder with a moisture content of 0.3%.

EXAMPLE 2. Prepare a water-dispersible preparation according to the claimed method with a ratio of components, wt. %: beta-carotene in gelatin microcapsules - 2.0, zinc glycinates - 1.0, iron - 1.0, manganese - 0.5, copper - 0.1, cobalt - 0.02, ceoiod - 0.01, DAFS-25 - 0.0035, vitamin C - 0.35, vitamin E - 0.6, DHA - 0.2, BOA - 0.002, chloroform - 200% by weight of beta-carotene, gelatin - 10, starch - up to 100 This corresponds to the average values of the components within the declared limits. Received a water-dispersible powder with a moisture content of 0.5%.

EXAMPLE 3. Prepare a water-dispersible preparation according to the claimed method with a ratio of components, wt. %: beta-carotene in gelatin microcapsules - 3.0, zinc glycinates - 1.5, iron - 1.8, manganese - 0.8, copper - 0.2, cobalt - 0.025, ceoiod - 0.02, DAFS - 25 - 0.007, vitamin C - 0.5, vitamin E - 0.9, DHA - 0.2, BOA - 0.002, gelatin - 10, chloroform - 200% by weight of beta-carotene, starch - up to 100. This corresponds to the maximum the values of the components within the declared limits. Received a water-dispersible powder with a moisture content of 0.7%.

EXAMPLE 4. Prepare a water-dispersible preparation according to the claimed method with a ratio of components, wt. %: beta-carotene in gelatin microcapsules - 3.5, zinc glycinates - 2.0, iron - 2.5, manganese - 1.0, copper - 0.4, cobalt - 0.03, ceoiod - 0.05, DAFS-25 - 0.005, vitamin C - 1.0, vitamin E - 1.3, DHA - 0.2, BOA - 0.002, gelatin - 10, chloroform - 200% by weight of beta-carotene, starch - up to 100. This corresponds to the prohibitive values of the components within the declared limits. Received a water-dispersible powder with a moisture content of 0.7%.

Determination of the biological activity of the drug was carried out on experimental groups of dairy cows for 30 months, according to the instructions for use. At the end of the experiment, studies were conducted to determine the effectiveness of the feed additive (table. 1, 2).

Information sources

1. Copyright certificate No. 1697696. Published 1992

2. Patent No. 2179401, A23L 1/30. Published 02/20/2002

3. Patent No. 2452194, A23K 1/00. Published June 10, 2012

4. Patent No. 2465783, A23K 1/175. Published November 10, 2012

5. Patent No. 2403801, A23K 1/14. Published November 20, 2010

6. Khokhrin S.N. Feeding farm animals / S.N. Hohrin. - M .: KolosS, 2004 .-- 692 p.

Claims (1)

Feed additive for the introduction into the diet of any farm animals, characterized in that it contains, by weight. %: beta-carotene in gelatin microcapsules - 1.0-3.0, zinc glycinates - 0.5-1.5, iron - 0.5-1.8, manganese - 0.3-0.8, copper - 0.01-0.2, cobalt - 0.015-0.025, ceoiod - 0.007-0.02, DAFS-25 - 0.0025-0.007, ascorbic acid - 0.25-0.5, antioxidants alpha-tocopherol acetate - 0 5-0.9, dihydroquercetin 0.2, stabilizer butyloxyanisole 0.002, gelatin 10, filler starch up to 100.