RU2599866C2 - Система и способ измерения концентрации радиофармацевтических препаратов - Google Patents

Система и способ измерения концентрации радиофармацевтических препаратов Download PDF

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RU2599866C2
RU2599866C2 RU2012147588/14A RU2012147588A RU2599866C2 RU 2599866 C2 RU2599866 C2 RU 2599866C2 RU 2012147588/14 A RU2012147588/14 A RU 2012147588/14A RU 2012147588 A RU2012147588 A RU 2012147588A RU 2599866 C2 RU2599866 C2 RU 2599866C2
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radiation
radiopharmaceutical
detector
container
radiation detector
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RU2012147588/14A
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English (en)
Russian (ru)
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RU2012147588A (ru
Inventor
Марк А. МАБИ
Ларри А. МАККАТЧЕН
Чад Е. БУТОН
Джеймс Е. ДВОРСКИ
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Байер Медикал Кэа Инк.,
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00—Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/16—Measuring radiation intensity
    • G01T1/167—Measuring radioactive content of objects, e.g. contamination
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00—Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/16—Measuring radiation intensity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00—Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/16—Measuring radiation intensity
    • G01T1/20—Measuring radiation intensity with scintillation detectors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T7/00—Details of radiation-measuring instruments
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T7/00—Details of radiation-measuring instruments
    • G01T7/02—Collecting means for receiving or storing samples to be investigated and possibly directly transporting the samples to the measuring arrangement; particularly for investigating radioactive fluids

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Measurement Of Radiation (AREA)
  • Nuclear Medicine (AREA)
RU2012147588/14A 2010-04-09 2011-04-11 Система и способ измерения концентрации радиофармацевтических препаратов RU2599866C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32255510P 2010-04-09 2010-04-09
US61/322,555 2010-04-09
PCT/US2011/031949 WO2011127469A1 (en) 2010-04-09 2011-04-11 Radiopharmaceutical concentration measurement system and method

Publications (2)

Publication Number Publication Date
RU2012147588A RU2012147588A (ru) 2014-05-20
RU2599866C2 true RU2599866C2 (ru) 2016-10-20

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Country Status (7)

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US (1) US9715020B2 (OSRAM)
EP (1) EP2563409A4 (OSRAM)
JP (1) JP6078463B2 (OSRAM)
KR (1) KR101803113B1 (OSRAM)
CN (1) CN102834119B (OSRAM)
RU (1) RU2599866C2 (OSRAM)
WO (1) WO2011127469A1 (OSRAM)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11752254B2 (en) 2016-09-20 2023-09-12 Bracco Diagnostics Inc. Radioisotope delivery system with multiple detectors to detect gamma and beta emissions
US11810685B2 (en) 2018-03-28 2023-11-07 Bracco Diagnostics Inc. Early detection of radioisotope generator end life
US12170153B2 (en) 2018-03-28 2024-12-17 Bracco Diagnostics Inc. Systems and techniques for calibrating radioisotope delivery systems with a gamma detector

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9436989B2 (en) 2011-06-03 2016-09-06 Bayer Healthcare Llc System and method for rapid quantitative dynamic molecular imaging scans
AU2012315757B9 (en) * 2011-09-30 2018-01-25 Ge Healthcare Limited Calibration and normalization systems and methods for radiopharmaceutical synthesizers
GB2497975B (en) * 2011-12-23 2016-05-11 Agilent Technologies Inc Adjustable aperture device with integral aperture holes
CA3174806A1 (en) 2012-09-05 2014-03-13 Jubilant Draximage, Inc. Rubidium elution system control
US10369276B2 (en) * 2013-11-25 2019-08-06 Bayer Healthcare Llc Accurately delivering partial doses of a drug post dilution using an injector
US20150309184A1 (en) * 2014-04-28 2015-10-29 Capintec, Inc. Communicating radioisotope dosage
RU2699307C2 (ru) 2014-12-16 2019-09-04 Конинклейке Филипс Н.В. Определение смещения базовой линии детектора фотонов
WO2018052447A1 (en) * 2016-09-19 2018-03-22 Siemens Medical Solutions Usa, Inc. Flexible application of cross-calibration for quantitative functional imaging
US10245002B2 (en) * 2017-08-01 2019-04-02 Siemens Medical Solutions Usa, Inc. Isotope specific calibration of a dose calibrator for quantitative functional imaging
EP3679405B1 (en) * 2017-09-06 2023-07-12 The U.S.A. as represented by the Secretary, Department of Health and Human Services Micro-dose calibrator
CN109521457B (zh) * 2018-09-25 2022-10-21 中国辐射防护研究院 一种基于信息准则的γ辐射源项划分方法及系统
CN109669204B (zh) 2019-01-08 2019-09-06 山西医科大学 一种czt半导体活度计以及活度测量装置
US11493662B2 (en) 2020-05-28 2022-11-08 Halliburton Energy Services, Inc. Determining density of multiple layers using gamma spectroscopy
CN111999763B (zh) * 2020-08-26 2022-12-30 山西医科大学 容纳装置及活度检测工位、活度检测方法
CN113484896B (zh) * 2021-07-01 2024-05-10 成都纽瑞特医疗科技股份有限公司 一种放射性物质检测装置
CN113945961A (zh) * 2021-10-21 2022-01-18 北京森科医药有限公司 药物标记设备和方法
FR3129000B1 (fr) * 2021-11-09 2025-01-10 Commissariat Energie Atomique Détecteur de rayonnement ionisant comportant un modulateur pour moduler l’intensité du rayonnement
CN118279423B (zh) * 2024-03-26 2024-10-29 合肥拓康科技有限公司 事件的符合事件个数校准方法、装置及电子设备
CN119361071B (zh) * 2024-12-25 2025-07-29 北京科技大学 一种用于成像注射前分析的放射性药物用量控制系统

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6362472B1 (en) * 1999-10-22 2002-03-26 Ethicon Endo-Surgery, Inc. Method for calibrating a radiation detection system
RU53880U1 (ru) * 2005-08-26 2006-06-10 Государственное научное учреждение "Объединенный институт проблем информатики Национальной академии наук Беларуси" ("ОИПИ НАН Беларуси") Устройство для регистрации ренографических исследований
RU2343965C2 (ru) * 2003-04-11 2009-01-20 Джи-И Хелткер Лимитед Способ получения галлия-68, его использование, а также устройство для осуществления указанного способа

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4307713A (en) * 1980-02-13 1981-12-29 Thomas Jefferson University Syringe shields and methods for using same
US4409488A (en) 1981-03-06 1983-10-11 King Russell W Radioactive material dose computer
US4853546A (en) 1986-09-16 1989-08-01 Ube Industries, Ltd. Automatic radioisotope filling apparatus
JPH0648319B2 (ja) * 1986-11-12 1994-06-22 宇部興産株式会社 ラジオアイソトープ自動分注装置及び自動分注方法
JPS63143354U (OSRAM) 1987-03-11 1988-09-21
JPH065297B2 (ja) * 1987-10-09 1994-01-19 浜松ホトニクス株式会社 核種弁別可能な線量計測装置
JPH0611003Y2 (ja) 1988-05-09 1994-03-23 日本メジフィジックス株式会社 放射性物質注射装置
JP3040326B2 (ja) * 1995-04-17 2000-05-15 アロカ株式会社 放射線測定装置
DE59600583D1 (de) 1995-05-03 1998-10-22 Oce Printing Systems Gmbh Reinigungsvorrichtung für die fotoleitertrommel eines druck- oder kopiergerätes
WO1996035131A1 (en) * 1995-05-05 1996-11-07 Capintec, Inc. Non-invasive radio nuclide detection meter
JPH1039033A (ja) * 1996-07-26 1998-02-13 Toshiba Corp 核種分析装置
US7373197B2 (en) * 2000-03-03 2008-05-13 Intramedical Imaging, Llc Methods and devices to expand applications of intraoperative radiation probes
US8565860B2 (en) * 2000-08-21 2013-10-22 Biosensors International Group, Ltd. Radioactive emission detector equipped with a position tracking system
US6767319B2 (en) 2001-06-29 2004-07-27 Medrad, Inc. Delivery methods, systems and components for use with hazardous pharmaceutical substances
WO2004004787A2 (en) 2002-07-05 2004-01-15 Universite Libre De Bruxelles - Hopital Erasme Method and device for dispensing individual doses of a radiopharmaceutical solution
EP1616587A1 (en) 2004-07-16 2006-01-18 Universität Zürich Method and device for accurate dispensing of radioactivity
JP4519699B2 (ja) 2005-04-07 2010-08-04 ジーイー・メディカル・システムズ・グローバル・テクノロジー・カンパニー・エルエルシー Ｘ線ｃｔ装置
FR2906475B1 (fr) * 2006-09-29 2009-01-09 Lemer Prot Anti X Par Abrevati Unite medicale pour le prelevement,le calibrage,la dilution et/ou l'injection d'un produit radioactif injectable
US9056164B2 (en) 2007-01-01 2015-06-16 Bayer Medical Care Inc. Radiopharmaceutical administration methods, fluid delivery systems and components thereof
US20080166292A1 (en) * 2007-01-01 2008-07-10 Medrad, Inc. Pharmaceutical Dosing Method

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6362472B1 (en) * 1999-10-22 2002-03-26 Ethicon Endo-Surgery, Inc. Method for calibrating a radiation detection system
RU2343965C2 (ru) * 2003-04-11 2009-01-20 Джи-И Хелткер Лимитед Способ получения галлия-68, его использование, а также устройство для осуществления указанного способа
RU53880U1 (ru) * 2005-08-26 2006-06-10 Государственное научное учреждение "Объединенный институт проблем информатики Национальной академии наук Беларуси" ("ОИПИ НАН Беларуси") Устройство для регистрации ренографических исследований

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11752254B2 (en) 2016-09-20 2023-09-12 Bracco Diagnostics Inc. Radioisotope delivery system with multiple detectors to detect gamma and beta emissions
US11865298B2 (en) 2016-09-20 2024-01-09 Bracco Diagnostics Inc. Systems and techniques for generating, infusing, and controlling radioisotope delivery
US12453813B2 (en) 2016-09-20 2025-10-28 Bracco Diagnostics, Inc. Radioisotope delivery system with multiple detectors to detect gamma and beta emissions
US11810685B2 (en) 2018-03-28 2023-11-07 Bracco Diagnostics Inc. Early detection of radioisotope generator end life
US12170153B2 (en) 2018-03-28 2024-12-17 Bracco Diagnostics Inc. Systems and techniques for calibrating radioisotope delivery systems with a gamma detector

Also Published As

Publication number Publication date
EP2563409A4 (en) 2016-10-26
JP6078463B2 (ja) 2017-02-08
RU2012147588A (ru) 2014-05-20
WO2011127469A1 (en) 2011-10-13
US9715020B2 (en) 2017-07-25
CN102834119A (zh) 2012-12-19
JP2013524245A (ja) 2013-06-17
EP2563409A1 (en) 2013-03-06
KR101803113B1 (ko) 2017-12-28
KR20130040880A (ko) 2013-04-24
CN102834119B (zh) 2015-02-04
US20130124103A1 (en) 2013-05-16

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Effective date: 20180412