RU2580035C2 - Модифицированные пептиды melk и содержащие их вакцины - Google Patents

Модифицированные пептиды melk и содержащие их вакцины Download PDF

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Publication number
RU2580035C2
RU2580035C2 RU2012136464/10A RU2012136464A RU2580035C2 RU 2580035 C2 RU2580035 C2 RU 2580035C2 RU 2012136464/10 A RU2012136464/10 A RU 2012136464/10A RU 2012136464 A RU2012136464 A RU 2012136464A RU 2580035 C2 RU2580035 C2 RU 2580035C2
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melk
peptide
cancer
peptides
present
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RU2012136464/10A
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English (en)
Russian (ru)
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RU2012136464A (ru
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Юсуке Накамура
Такуя Цунода
Рюдзи ОХСАВА
Сатико Йосимура
Томохиса Ватанабе
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Онкотерапи Сайенс, Инк.
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/11—Protein-serine/threonine kinases (2.7.11)
    • C12Y207/11025—Mitogen-activated protein kinase kinase kinase (2.7.11.25), i.e. MAPKKK or MAP3K
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001154—Enzymes
    • A61K39/001162—Kinases, e.g. Raf or Src
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Reproductive Health (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
RU2012136464/10A 2010-01-25 2011-01-24 Модифицированные пептиды melk и содержащие их вакцины RU2580035C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29799610P 2010-01-25 2010-01-25
US61/297,996 2010-01-25
PCT/JP2011/000352 WO2011089921A1 (en) 2010-01-25 2011-01-24 Modified melk peptides and vaccines containing the same

Publications (2)

Publication Number Publication Date
RU2012136464A RU2012136464A (ru) 2014-03-10
RU2580035C2 true RU2580035C2 (ru) 2016-04-10

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RU2012136464/10A RU2580035C2 (ru) 2010-01-25 2011-01-24 Модифицированные пептиды melk и содержащие их вакцины

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Country Link
US (1) US8871719B2 (enExample)
EP (1) EP2528937B1 (enExample)
JP (1) JP5884104B2 (enExample)
KR (1) KR101841475B1 (enExample)
CN (1) CN102822193B (enExample)
AU (1) AU2011208271B2 (enExample)
BR (1) BR112012018457A2 (enExample)
CA (1) CA2787369A1 (enExample)
MX (1) MX2012008657A (enExample)
RU (1) RU2580035C2 (enExample)
SG (1) SG182580A1 (enExample)
TW (1) TWI485245B (enExample)
WO (1) WO2011089921A1 (enExample)

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JP6077544B2 (ja) * 2011-09-07 2017-02-08 ミダテック リミテッド ナノ粒子−ペプチド組成物
KR20140138900A (ko) 2012-03-09 2014-12-04 온코세라피 사이언스 가부시키가이샤 펩티드를 포함한 의약 조성물
TWI714869B (zh) * 2013-08-05 2021-01-01 德商伊瑪提克斯生物科技有限公司 新穎肽類，細胞及其用於治療多種腫瘤的用途，其製造方法及包含其等之醫藥組成物
ES2900004T3 (es) 2013-08-05 2022-03-15 Immatics Biotechnologies Gmbh Nueva inmunoterapia contra diversos tumores como el cáncer de pulmón, incluido el carcinoma de pulmón amicrocítico (NSCLC)
AU2017318907B2 (en) * 2016-08-31 2023-07-06 Oncotherapy Science, Inc. Monoclonal antibody against MELK and utilization thereof
AU2019384820B2 (en) * 2018-11-21 2026-02-12 Endomet Biosciences, Inc. Compositions and methods for treating endometriosis

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WO2004070062A2 (en) * 2003-02-04 2004-08-19 Wyeth Compositions and methods for diagnosing and treating cancers
WO2005073374A1 (ja) * 2004-01-29 2005-08-11 Dainippon Sumitomo Pharma Co., Ltd. 新規腫瘍抗原蛋白質及びその利用
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Publication number Publication date
US8871719B2 (en) 2014-10-28
RU2012136464A (ru) 2014-03-10
AU2011208271A1 (en) 2012-08-16
CN102822193A (zh) 2012-12-12
KR20120127467A (ko) 2012-11-21
TW201130972A (en) 2011-09-16
CN102822193B (zh) 2016-03-30
MX2012008657A (es) 2013-05-30
CA2787369A1 (en) 2011-07-28
EP2528937B1 (en) 2019-05-08
JP5884104B2 (ja) 2016-03-15
AU2011208271B2 (en) 2015-04-09
SG182580A1 (en) 2012-08-30
BR112012018457A2 (pt) 2017-01-10
TWI485245B (zh) 2015-05-21
US20130034574A1 (en) 2013-02-07
KR101841475B1 (ko) 2018-03-23
EP2528937A1 (en) 2012-12-05
JP2013517764A (ja) 2013-05-20
WO2011089921A1 (en) 2011-07-28
EP2528937A4 (en) 2013-07-03

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Effective date: 20180125