KR101841475B1 - 변형된 ｍｅｌｋ 펩티드 및 이를 함유하는 백신 - Google Patents

변형된 ｍｅｌｋ 펩티드 및 이를 함유하는 백신 Download PDF

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Publication number
KR101841475B1
KR101841475B1 KR1020127021961A KR20127021961A KR101841475B1 KR 101841475 B1 KR101841475 B1 KR 101841475B1 KR 1020127021961 A KR1020127021961 A KR 1020127021961A KR 20127021961 A KR20127021961 A KR 20127021961A KR 101841475 B1 KR101841475 B1 KR 101841475B1
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South Korea
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peptide
peptides
cancer
melk
present
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Korean (ko)
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KR20120127467A (ko
Inventor
유스케 나카무라
타쿠야 츠노다
류지 오사와
사치코 요시무라
토모히사 와타나베
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온코세라피 사이언스 가부시키가이샤
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Publication of KR20120127467A publication Critical patent/KR20120127467A/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/11—Protein-serine/threonine kinases (2.7.11)
    • C12Y207/11025—Mitogen-activated protein kinase kinase kinase (2.7.11.25), i.e. MAPKKK or MAP3K
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001154—Enzymes
    • A61K39/001162—Kinases, e.g. Raf or Src
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Reproductive Health (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020127021961A 2010-01-25 2011-01-24 변형된 ｍｅｌｋ 펩티드 및 이를 함유하는 백신 Expired - Fee Related KR101841475B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29799610P 2010-01-25 2010-01-25
US61/297,996 2010-01-25
PCT/JP2011/000352 WO2011089921A1 (en) 2010-01-25 2011-01-24 Modified melk peptides and vaccines containing the same

Publications (2)

Publication Number Publication Date
KR20120127467A KR20120127467A (ko) 2012-11-21
KR101841475B1 true KR101841475B1 (ko) 2018-03-23

Family

ID=44306725

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020127021961A Expired - Fee Related KR101841475B1 (ko) 2010-01-25 2011-01-24 변형된 ｍｅｌｋ 펩티드 및 이를 함유하는 백신

Country Status (13)

Country Link
US (1) US8871719B2 (enExample)
EP (1) EP2528937B1 (enExample)
JP (1) JP5884104B2 (enExample)
KR (1) KR101841475B1 (enExample)
CN (1) CN102822193B (enExample)
AU (1) AU2011208271B2 (enExample)
BR (1) BR112012018457A2 (enExample)
CA (1) CA2787369A1 (enExample)
MX (1) MX2012008657A (enExample)
RU (1) RU2580035C2 (enExample)
SG (1) SG182580A1 (enExample)
TW (1) TWI485245B (enExample)
WO (1) WO2011089921A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20140084020A (ko) * 2011-09-07 2014-07-04 미다테크 리미티드 나노입자 종양 백신
AU2012306243B2 (en) * 2011-09-07 2016-10-20 Midatech Limited Nanoparticle-peptide compositions
KR20140138900A (ko) 2012-03-09 2014-12-04 온코세라피 사이언스 가부시키가이샤 펩티드를 포함한 의약 조성물
TWI819228B (zh) * 2013-08-05 2023-10-21 德商伊瑪提克斯生物科技有限公司 新穎肽類，細胞及其用於治療多種腫瘤的用途，其製造方法及包含其等之醫藥組成物（八）
ES3010561T3 (en) 2013-08-05 2025-04-03 Immatics Biotechnologies Gmbh Novel immunotherapy against several tumors, such as lung cancer including nsclc
RU2756982C2 (ru) * 2016-08-31 2021-10-07 Онкотерапи Сайенс, Инк. Моноклональное антитело против melk и его использование
CN113557030A (zh) * 2018-11-21 2021-10-26 恩多梅特生物科学公司 用于治疗子宫内膜异位症的组合物和方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005073374A1 (ja) * 2004-01-29 2005-08-11 Dainippon Sumitomo Pharma Co., Ltd. 新規腫瘍抗原蛋白質及びその利用

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GB8823869D0 (en) 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
US6150584A (en) 1990-01-12 2000-11-21 Abgenix, Inc. Human antibodies derived from immunized xenomice
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
US5625126A (en) 1990-08-29 1997-04-29 Genpharm International, Inc. Transgenic non-human animals for producing heterologous antibodies
US5633425A (en) 1990-08-29 1997-05-27 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
US5661016A (en) 1990-08-29 1997-08-26 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
CA2089661C (en) 1990-08-29 2007-04-03 Nils Lonberg Transgenic non-human animals capable of producing heterologous antibodies
KR100209784B1 (ko) 1996-10-08 1999-07-15 박원훈 인간 단백질 변이인산화효소 유전자(hpk 38), 그의 염기 서열, 효소 단백질 및 그의 아미노산 서열
US6229001B1 (en) 1997-01-03 2001-05-08 Southern Research Institute Mycobacterium fol a gene that encodes for the enzyme dihydrofolate reductase
US6605709B1 (en) 1999-04-09 2003-08-12 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to Proteus mirabilis for diagnostics and therapeutics
US6974867B2 (en) 2000-05-31 2005-12-13 Chiron Corporation Compositions and methods for treating neoplastic disease using chemotherapy and radiation sensitizers
US6833447B1 (en) 2000-07-10 2004-12-21 Monsanto Technology, Llc Myxococcus xanthus genome sequences and uses thereof
US20020156263A1 (en) 2000-10-05 2002-10-24 Huei-Mei Chen Genes expressed in breast cancer
GB0103424D0 (en) 2001-02-12 2001-03-28 Chiron Spa Gonococcus proteins
WO2003065006A2 (en) 2002-01-31 2003-08-07 Millennium Pharmaceuticals, Inc. Methods and compositions for treating cancer
EP2298904B1 (en) 2002-06-14 2017-05-24 BP Corporation North America Inc. Xylanases, nucleic acids encoding them and methods for making and using them
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Also Published As

Publication number Publication date
JP5884104B2 (ja) 2016-03-15
AU2011208271A1 (en) 2012-08-16
SG182580A1 (en) 2012-08-30
EP2528937A4 (en) 2013-07-03
EP2528937A1 (en) 2012-12-05
KR20120127467A (ko) 2012-11-21
US8871719B2 (en) 2014-10-28
AU2011208271B2 (en) 2015-04-09
WO2011089921A1 (en) 2011-07-28
RU2012136464A (ru) 2014-03-10
CN102822193B (zh) 2016-03-30
CN102822193A (zh) 2012-12-12
TWI485245B (zh) 2015-05-21
US20130034574A1 (en) 2013-02-07
MX2012008657A (es) 2013-05-30
BR112012018457A2 (pt) 2017-01-10
TW201130972A (en) 2011-09-16
EP2528937B1 (en) 2019-05-08
RU2580035C2 (ru) 2016-04-10
JP2013517764A (ja) 2013-05-20
CA2787369A1 (en) 2011-07-28

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