RU2553379C2 - ОПРЕДЕЛЕНИЕ ЧУВСТВИТЕЛЬНОСТИ КЛЕТОК К ОБРАБОТКЕ ИНГИБИТОРОМ B-Raf ПУТЕМ ДЕТЕКЦИИ МУТАЦИИ K-ras И УРОВНЕЙ ЭКСПРЕССИИ RTK - Google Patents

ОПРЕДЕЛЕНИЕ ЧУВСТВИТЕЛЬНОСТИ КЛЕТОК К ОБРАБОТКЕ ИНГИБИТОРОМ B-Raf ПУТЕМ ДЕТЕКЦИИ МУТАЦИИ K-ras И УРОВНЕЙ ЭКСПРЕССИИ RTK Download PDF

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RU2553379C2
RU2553379C2 RU2012111231/15A RU2012111231A RU2553379C2 RU 2553379 C2 RU2553379 C2 RU 2553379C2 RU 2012111231/15 A RU2012111231/15 A RU 2012111231/15A RU 2012111231 A RU2012111231 A RU 2012111231A RU 2553379 C2 RU2553379 C2 RU 2553379C2
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ras
raf
mutant
inhibitor
cancer
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RU2012111231/15A
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Russian (ru)
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RU2012111231A (ru
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Джорджия ХАТЗИВАССИЛИУ
Шива МАЛЕК
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Дженентек, Инк.
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    • A61K31/33—Heterocyclic compounds
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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RU2012111231/15A 2009-08-24 2010-08-24 ОПРЕДЕЛЕНИЕ ЧУВСТВИТЕЛЬНОСТИ КЛЕТОК К ОБРАБОТКЕ ИНГИБИТОРОМ B-Raf ПУТЕМ ДЕТЕКЦИИ МУТАЦИИ K-ras И УРОВНЕЙ ЭКСПРЕССИИ RTK RU2553379C2 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US23646609P 2009-08-24 2009-08-24
US61/236,466 2009-08-24
US30114910P 2010-02-03 2010-02-03
US61/301,149 2010-02-03
PCT/US2010/046520 WO2011028540A1 (en) 2009-08-24 2010-08-24 Determining sensitivity of cells to b-raf inhibitor treatment by detecting kras mutation and rtk expression levels

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RU2015104058/15A Division RU2015104058A (ru) 2009-08-24 2010-08-24 ОПРЕДЕЛЕНИЕ ЧУВСТВИТЕЛЬНОСТИ КЛЕТОК К ОБРАБОТКЕ ИНГИБИТОРОМ B-Raf ПУТЕМ ДЕТЕКЦИИ МУТАЦИИ KRAS И УРОВНЕЙ ЭКСПРЕССИИ RTK

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RU2012111231A RU2012111231A (ru) 2013-10-10
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RU2012111231/15A RU2553379C2 (ru) 2009-08-24 2010-08-24 ОПРЕДЕЛЕНИЕ ЧУВСТВИТЕЛЬНОСТИ КЛЕТОК К ОБРАБОТКЕ ИНГИБИТОРОМ B-Raf ПУТЕМ ДЕТЕКЦИИ МУТАЦИИ K-ras И УРОВНЕЙ ЭКСПРЕССИИ RTK
RU2015104058/15A RU2015104058A (ru) 2009-08-24 2010-08-24 ОПРЕДЕЛЕНИЕ ЧУВСТВИТЕЛЬНОСТИ КЛЕТОК К ОБРАБОТКЕ ИНГИБИТОРОМ B-Raf ПУТЕМ ДЕТЕКЦИИ МУТАЦИИ KRAS И УРОВНЕЙ ЭКСПРЕССИИ RTK

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US (2) US20120214828A1 (2)
EP (1) EP2470898A4 (2)
JP (1) JP2013502236A (2)
KR (1) KR20120050493A (2)
CN (1) CN102859355B (2)
AU (1) AU2010289794B2 (2)
BR (1) BR112012003926A2 (2)
CA (1) CA2771369A1 (2)
IL (2) IL218099A0 (2)
IN (1) IN2012DN01403A (2)
MX (1) MX338856B (2)
MY (1) MY165154A (2)
RU (2) RU2553379C2 (2)
SG (2) SG178866A1 (2)
WO (1) WO2011028540A1 (2)

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