RU2552683C2 - Одноразовый поршневой насос и механизм для внутривенного вливания - Google Patents

Одноразовый поршневой насос и механизм для внутривенного вливания Download PDF

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Publication number
RU2552683C2
RU2552683C2 RU2011148141/14A RU2011148141A RU2552683C2 RU 2552683 C2 RU2552683 C2 RU 2552683C2 RU 2011148141/14 A RU2011148141/14 A RU 2011148141/14A RU 2011148141 A RU2011148141 A RU 2011148141A RU 2552683 C2 RU2552683 C2 RU 2552683C2
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RU
Russia
Prior art keywords
valve
channel
pumping
suction cavity
exhaust pipe
Prior art date
Application number
RU2011148141/14A
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English (en)
Russian (ru)
Other versions
RU2011148141A (ru
Inventor
Брет Х. ФРЭНКС
Original Assignee
Кэафьюжн 303, Инк.
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Application filed by Кэафьюжн 303, Инк. filed Critical Кэафьюжн 303, Инк.
Publication of RU2011148141A publication Critical patent/RU2011148141A/ru
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Publication of RU2552683C2 publication Critical patent/RU2552683C2/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14212—Pumping with an aspiration and an expulsion action
    • A61M5/14216—Reciprocating piston type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22—Valves or arrangement of valves
    • A61M39/223—Multiway valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14212—Pumping with an aspiration and an expulsion action
    • A61M5/14216—Reciprocating piston type
    • A61M5/1422—Reciprocating piston type with double acting or multiple pistons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters
    • A61M5/16877—Passive flow controllers; Devices for setting a flow rate
    • A61M5/16881—Regulating valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/36—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests with means for eliminating or preventing injection or infusion of air into body
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B1/00—Multi-cylinder machines or pumps characterised by number or arrangement of cylinders
    • F04B1/04—Multi-cylinder machines or pumps characterised by number or arrangement of cylinders having cylinders in star- or fan-arrangement
    • F04B1/06—Control
    • F04B1/063—Control by using a valve in a system with several pumping chambers wherein the flow-path through the chambers can be changed, e.g. between series and parallel flow
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B27/00—Multi-cylinder pumps specially adapted for elastic fluids and characterised by number or arrangement of cylinders
    • F04B27/04—Multi-cylinder pumps specially adapted for elastic fluids and characterised by number or arrangement of cylinders having cylinders in star- or fan-arrangement
    • F04B27/067—Control
    • F04B27/0673—Control by using a valve in a system with several pumping chambers, wherein the flow-path through the chambers can be changed, e.g. series-parallel
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K11/00—Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves
    • F16K11/02—Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves with all movable sealing faces moving as one unit
    • F16K11/08—Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves with all movable sealing faces moving as one unit comprising only taps or cocks
    • F16K11/085—Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves with all movable sealing faces moving as one unit comprising only taps or cocks with cylindrical plug
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K5/00—Plug valves; Taps or cocks comprising only cut-off apparatus having at least one of the sealing faces shaped as a more or less complete surface of a solid of revolution, the opening and closing movement being predominantly rotary
    • F16K5/04—Plug valves; Taps or cocks comprising only cut-off apparatus having at least one of the sealing faces shaped as a more or less complete surface of a solid of revolution, the opening and closing movement being predominantly rotary with plugs having cylindrical surfaces; Packings therefor
    • F16K5/0407—Plug valves; Taps or cocks comprising only cut-off apparatus having at least one of the sealing faces shaped as a more or less complete surface of a solid of revolution, the opening and closing movement being predominantly rotary with plugs having cylindrical surfaces; Packings therefor with particular plug arrangements, e.g. particular shape or built-in means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M2005/1401—Functional features
    • A61M2005/1402—Priming
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M2005/1401—Functional features
    • A61M2005/1403—Flushing or purging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons pressurised by means of pistons
    • A61M2005/14533—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons pressurised by means of pistons cam actuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22—Valves or arrangement of valves
    • A61M39/223—Multiway valves
    • A61M2039/224—Multiway valves of the slide-valve type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/12—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit
    • A61M2205/128—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit with incorporated valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/22—Flow characteristics eliminating pulsatile flows, e.g. by the provision of a dampening chamber
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22—Valves or arrangement of valves
    • A61M39/229—Single-way cut-off valves

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Mechanical Engineering (AREA)
  • Pulmonology (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Emergency Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • External Artificial Organs (AREA)
  • Reciprocating Pumps (AREA)
  • Details Of Reciprocating Pumps (AREA)
RU2011148141/14A 2009-05-27 2010-05-26 Одноразовый поршневой насос и механизм для внутривенного вливания RU2552683C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12/472,710 2009-05-27
US12/472,710 US8733736B2 (en) 2009-05-27 2009-05-27 Intravenous piston pump disposable and mechanism
PCT/US2010/036230 WO2010138612A2 (en) 2009-05-27 2010-05-26 Intravenous piston pump disposable and mechanism

Publications (2)

Publication Number Publication Date
RU2011148141A RU2011148141A (ru) 2013-05-27
RU2552683C2 true RU2552683C2 (ru) 2015-06-10

Family

ID=43221044

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2011148141/14A RU2552683C2 (ru) 2009-05-27 2010-05-26 Одноразовый поршневой насос и механизм для внутривенного вливания

Country Status (11)

Country Link
US (2) US8733736B2 (cg-RX-API-DMAC10.html)
EP (2) EP3456368B1 (cg-RX-API-DMAC10.html)
JP (1) JP5785938B2 (cg-RX-API-DMAC10.html)
KR (1) KR101807882B1 (cg-RX-API-DMAC10.html)
CN (1) CN102481408B (cg-RX-API-DMAC10.html)
AU (1) AU2010254096B2 (cg-RX-API-DMAC10.html)
BR (1) BRPI1010606B8 (cg-RX-API-DMAC10.html)
CA (2) CA2762828C (cg-RX-API-DMAC10.html)
MX (2) MX394405B (cg-RX-API-DMAC10.html)
RU (1) RU2552683C2 (cg-RX-API-DMAC10.html)
WO (1) WO2010138612A2 (cg-RX-API-DMAC10.html)

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DE102009032399A1 (de) * 2009-07-08 2011-01-13 Sata Gmbh & Co. Kg Farbspritzpistole
CA2849486C (en) * 2011-09-21 2017-12-12 Bayer Medical Care Inc. Continuous multi-fluid pump device, drive and actuating system, and method
WO2015106107A1 (en) 2014-01-10 2015-07-16 Bayer Medical Care Inc. Single-use disposable set connector
DK2921189T3 (da) * 2014-03-17 2017-11-13 Hoffmann La Roche Initialisering af en doseringsenhed til lægemiddelsinfusion
ES3030489T3 (en) 2015-01-09 2025-06-30 Bayer Healthcare Llc Multiple fluid delivery system with multi-use disposable set and features thereof
US10632829B2 (en) * 2015-02-20 2020-04-28 Vianney Rabhi Distributer phase shifter for a hydraulic pump motor
EP3344903B1 (en) * 2015-08-31 2019-09-25 bNovate Technologies SA Rotary valve and pump system with rotary valve
EP3135965A1 (en) * 2015-08-31 2017-03-01 bNovate Technologies SA Pump system with rotary valve
TWI651107B (zh) 2016-06-15 2019-02-21 拜耳保健公司 多次使用可棄式系統及用於該系統之注射器
US10247313B2 (en) * 2017-06-29 2019-04-02 Tao-Pao Chien Spray gun and adjustment valve thereof
US10595761B2 (en) 2017-11-01 2020-03-24 Edwards Lifesciences Corporation Adapter for use with a multi-port control valve used in blood sampling, blood pressure measurement systems
US20190125232A1 (en) 2017-11-01 2019-05-02 Edwards Lifesciences Corporation Multi-port control valve for use in blood sampling, blood pressure measurement systems
JP6596057B2 (ja) * 2017-11-27 2019-10-23 本田技研工業株式会社 流量調整構造体及び流量調整方法
EP3502469A1 (en) * 2017-12-20 2019-06-26 Sensile Medical AG Micropump
EP3505757A1 (en) 2017-12-28 2019-07-03 Sensile Medical AG Micropump
CN111989486B (zh) * 2018-04-19 2022-07-19 贝克顿·迪金森公司 自动泵送注射器
ES2968846T3 (es) * 2018-05-02 2024-05-14 Cequr Sa Dispositivos y métodos para proporcionar una dosis en bolo en un circuito microfluídico de una bomba
US20210016287A1 (en) * 2019-07-16 2021-01-21 Ge Healthcare Bio-Sciences Corp. Reinforced bioreactor component structure system for cell cultivation
CN111803759B (zh) * 2020-07-20 2022-11-18 张正伟 恒温加热输液灌注治疗泵
GB2611362B (en) * 2021-10-04 2026-04-22 Aspen Pumps Ltd Condensate pump assembly & control methods
US12453846B2 (en) 2021-11-24 2025-10-28 Boston Scientific Scimed, Inc. Stopcock with indexing mechanism providing feedback of hub position
WO2026078433A1 (en) * 2024-10-07 2026-04-16 Vijayakrishnan Sankaranthampi An assembly for maintaining constant volume in a push-through gate valve and a method thereof

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US4605396A (en) * 1985-02-25 1986-08-12 Warner-Lambert Company Gravity flow cassette with rotary valve
US4850980A (en) * 1987-12-04 1989-07-25 Fisher Scientific Company I.V. pump cassette
US5971912A (en) * 1996-01-31 1999-10-26 Atom Medical Corporation Fluid flow controlling device and an incubator incorporating the same therein
US6500156B1 (en) * 2000-10-03 2002-12-31 Mckinley Medical L.L.L.P Thumb-powered flushing device for catheters
RU2325927C2 (ru) * 2002-03-14 2008-06-10 Медакс Аб Инфузионный насос
US7462170B2 (en) * 2004-05-25 2008-12-09 Covidien Ag Administration feeding set and valve mechanism

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US3306291A (en) * 1964-04-14 1967-02-28 Burron Medical Prod Inc Disposable sterile syringes, needle containers and the like having prestressed frangible portions therein
US4382753A (en) * 1979-03-09 1983-05-10 Avi, Inc. Nonpulsating IV pump and disposable pump chamber
US4534758A (en) * 1983-07-15 1985-08-13 Eli Lilly & Company Controlled release infusion system
US5195526A (en) * 1988-03-11 1993-03-23 Michelson Gary K Spinal marker needle
US4904245A (en) * 1988-12-07 1990-02-27 Allen S. Chen Surgical valve assembly for urinary bladder irrigation and drainage
US5057087A (en) * 1989-04-24 1991-10-15 Harmon James E Hypodermic needle safety system
NO311186B1 (no) * 1999-12-13 2001-10-22 Techwood As Ventilanordning for styrt tilförsel av et trykkfluid
CN1325126C (zh) * 2001-11-16 2007-07-11 梅德创新股份公司 医药用的泵装置
US7951112B2 (en) * 2007-05-16 2011-05-31 Smiths Medical Asd, Inc. Pump module for use in a medical fluid dispensing system
US20090264720A1 (en) * 2008-04-17 2009-10-22 The Cooper Health System Wearable Automated Blood Sampling and Monitoring System
US8052656B2 (en) * 2009-02-10 2011-11-08 Tyco Healthcare Group Lp Enteral feeding system

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4605396A (en) * 1985-02-25 1986-08-12 Warner-Lambert Company Gravity flow cassette with rotary valve
US4850980A (en) * 1987-12-04 1989-07-25 Fisher Scientific Company I.V. pump cassette
US5971912A (en) * 1996-01-31 1999-10-26 Atom Medical Corporation Fluid flow controlling device and an incubator incorporating the same therein
US6500156B1 (en) * 2000-10-03 2002-12-31 Mckinley Medical L.L.L.P Thumb-powered flushing device for catheters
RU2325927C2 (ru) * 2002-03-14 2008-06-10 Медакс Аб Инфузионный насос
US7462170B2 (en) * 2004-05-25 2008-12-09 Covidien Ag Administration feeding set and valve mechanism

Also Published As

Publication number Publication date
EP3456368B1 (en) 2020-10-07
BRPI1010606A2 (pt) 2016-03-15
JP2012527972A (ja) 2012-11-12
US8733736B2 (en) 2014-05-27
WO2010138612A3 (en) 2011-04-14
EP2435110B1 (en) 2018-08-29
EP3456368A2 (en) 2019-03-20
EP2435110A4 (en) 2017-04-26
US20100305508A1 (en) 2010-12-02
EP2435110A2 (en) 2012-04-04
MX394405B (es) 2025-03-24
MX2011012476A (es) 2012-09-28
CA2762828A1 (en) 2010-12-02
US20140221973A1 (en) 2014-08-07
CA2762828C (en) 2019-02-12
WO2010138612A2 (en) 2010-12-02
US9566385B2 (en) 2017-02-14
JP5785938B2 (ja) 2015-09-30
MX341914B (es) 2016-09-07
BRPI1010606B1 (pt) 2020-08-18
CN102481408A (zh) 2012-05-30
CA3027944C (en) 2020-12-15
EP3456368A3 (en) 2019-05-22
RU2011148141A (ru) 2013-05-27
CN102481408B (zh) 2015-04-01
CA3027944A1 (en) 2010-12-02
AU2010254096A1 (en) 2011-12-15
KR20120017049A (ko) 2012-02-27
AU2010254096B2 (en) 2015-09-03
KR101807882B1 (ko) 2018-01-18
BRPI1010606B8 (pt) 2021-06-22

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