RU2535031C2 - Disinfectant "dermamber" - Google Patents

Abstract

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to disinfectants of wide spectrum applied in medicine, veterinary, food industry, communal household sphere, public catering enterprises, laboratories of any profile, and is intended for treatment of hands, treatment of patients' operation and injection field skin, decontamination of gloves, put on hands of medical staff, disinfection of difficult for access surface at enterprises of food industry, public catering, as well as in any other organisations. Invention represents disinfectant, which contains octenidine dihydrochloride, propanol-1, propanol-2, citric acid, lavender essential oil and softened water.

EFFECT: invention provides creation of highly efficient disinfectant, which possesses high antimicrobial activity with respect to Gram-positive and Gram-negative bacteria, fungi of genus Candida and Trichophyton, as well as viruses.

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Description

The invention relates to disinfectants used in medicine, veterinary medicine, food industry, public utilities, catering, laboratories of any profile, and is intended for the treatment of hands, skin treatment of the surgical and injection fields of patients, disinfection of gloves worn by the hands of medical personnel , disinfection of hard-to-reach surfaces at the enterprises of the food industry, catering, as well as in any other organizations.

A disinfectant is known containing isopropanol, alkyldimethylbenzylammonium chloride, propylene glycol and water.

(Japan, 3258701, A61L 2/00, 1991)

The disadvantage of this tool is the low antimicrobial effectiveness, as well as the inability to use as a skin antiseptic and the absence of a prolonged action.

Known disinfectant "Sonata-Des" containing alkyldimethylbenzylammonium chloride, glyoxal, glutaraldehyde, propanol-2, syntanol ALM-10, Trilon B, anticorrosive substance and oxidizing agent.

(RU 2337715 C1, A1L 2/18, 2008)

Known disinfectant "Mixamin-septic" containing isopropanol, polyhexamethylene biguanide hydrochloride, alkyldimethylbenzylammonium chloride, propylene glycol and water.

(RU 2465012 C1, A61L 2/16, 10.27.2012)

These funds provide increased antimicrobial activity, but do not have a wide spectrum of action.

The closest in technical essence and the achieved result is a disinfectant "Okteniderm" for the treatment of hands of medical personnel, as well as for treating the skin of the surgical and injection fields, containing 1-propanol, 2-propanol, octenidine dihydrochloride.

(Guidelines for the use of the disinfectant "Okteniderm" of the company "Schulke and Mayr GmbH" (Germany), approved by the Ministry of Health of the Russian Federation, M., 2002)

However, this tool is not effective enough and does not have a general disinfecting effect.

The objective of the present invention is to develop a highly effective domestic disinfectant "Dermamber" prolonged action with a wide range of effects for treating hands, treating the skin of the surgical and injection fields of patients, disinfection of gloves worn by the hands of medical personnel, disinfection of hard-to-reach surfaces.

The technical result obtained by using the invention is expressed in the high effect of a disinfectant having high antimicrobial activity against gram-positive and gram-negative bacteria (including E. coli bacteria, staphylococci, mycobacteria) Candida and Trichophyton fungi, as well as viruses (including adenoviruses , all types of influenza viruses, including avian influenza H5N1 viruses, swine flu A / H1N1, parainfluenza, acute respiratory infections, enteroviruses, rotavirus c, poliomyelitis virus, enteric and parenteral hepatitis viruses, herpes, SARS, HIV.

To achieve the technical result, a disinfectant containing octenidine dihydrochloride, propanol-1, propanol-2, according to the invention, it additionally contains citric acid, lavender essential oil (natural antiseptic) and water softened in the following ratio of components, in mass. %:

octenidine dihydrochloride 0.01-0.2 propanol-1 20-35 propanol-2 40-50 citric acid 0.001-0.003 lavender essential oil 0.1-0.5 softened water rest

The analysis of the prior art by the applicants, including a search by patent and scientific and technical sources of information, and the identification of sources containing information about analogues of the claimed disinfectant, allowed us to establish that the applicants did not find an analogue characterized by signs that are identical (identical) to all essential features of the claimed means.

The definition from the list of identified analogues of the prototype made it possible to identify a set of essential distinguishing features in relation to the seen technical result in the claimed tool set forth in the claims.

Therefore, the claimed disinfectant meets the criterion of "novelty."

To verify the compliance of the claimed disinfectant, the applicants conducted an additional search for known solutions to identify signs that match the distinctive features of the claimed invention from the prototype.

The search results showed that the claimed invention does not follow explicitly from the prior art as determined by the applicants for the specialist, the effect of the transformations provided for by the essential features of the claimed disinfectant on the achievement of the technical result is not revealed.

Therefore, the claimed invention meets the criterion of "inventive step".

The criteria of the invention "industrial applicability" is confirmed by the fact that the proposed disinfectant "Dermamber", with increased antimicrobial activity and a wide spectrum of action, can be successfully used for treating hands, treating the skin of the surgical and injection fields of patients, disinfecting gloves worn on the hands of medical personnel , disinfection of hard-to-reach surfaces at the enterprises of the food industry, catering, as well as in any other organizations.

The present invention is illustrated by a specific example of execution, which, however, is not the only possible, but clearly demonstrates the possibility of achieving the desired technical result.

Example 1. Dermamber disinfectant is a ready-to-use solution in the form of a clear, colorless liquid with an alcohol smell, containing octenidine dihydrochloride, propanol-1, propanol-2, citric acid, lavender essential oil and softened water.

The technology for obtaining funds is the same for all options. Prepare a mixture of these components, bring them into one container in a given sequence and sterilize. All components are mixed. The resulting product is placed in the required container, sealed and marked.

These components are taken in the following components in wt.%:

Options one 2 3 octenidine dihydrochloride 0.1 0.15 0.2 propanol-1 twenty 25 35 propanol-2 40 45 fifty citric acid 0.001 0.0015 0.003 lavender essential oil 0.1 0.3 0.5 softened water the rest is up to 100

Example 2. A disinfectant is used as follows.

For hygienic processing of hands: at least 2 ml of the product is applied to dry hands (without preliminary washing with water and soap) and rubbed into the skin until it dries, but for at least 40 seconds, paying attention to the thorough processing of the skin between the fingers and fingertips.

For the prevention of tuberculosis and viral infections, the hands are treated twice, using at least 3 ml of the product each time, the total treatment time is at least 2 minutes.

To handle the hands of surgeons, operating nurses, midwives and other persons involved in operations, before using the hand and forearm, wash with warm running water and toilet soap for 2 minutes and then dry with a sterile cloth. Then 5 ml of the product is applied to the hands and rubbed into the skin of the hands and forearms for 3 minutes; then again apply 5 ml of the product to the hands and rub it into the skin of the hands and arms for 2 minutes, the total processing time is 7 minutes Sterile gloves are worn on the hands after the product has completely dried.

On the day of treatment of the skin of the surgical field, elbow bends of the donors, the skin before the introduction of catheters and puncture of the joints, the skin is wiped twice with sterile gauze swabs, abundantly dampened with the product. The exposure time after treatment is 2 minutes On the eve of surgery, the patient takes a shower (bath), changes clothes.

To treat the injection field, the skin is wiped with a sterile cotton swab, liberally moistened with a product. The exposure time after processing is 30 seconds.

For the disinfection of small surface areas or hard-to-reach surfaces in rooms, surfaces of devices, apparatuses, medical equipment; on sanitary transport is carried out by wiping or irrigation. The consumption rate of the product is -70 ml / m ^{2 of the} treated surface.

Surfaces in rooms, on sanitary transport, furnishings, devices, medical equipment are uniformly sprayed with a spray nozzle from a distance of 30 cm until they are completely wetted or wiped with a cloth moistened with plenty of water

Thus, the claimed disinfectant with high antimicrobial activity against gram-positive and gram-negative bacteria, fungi, viruses, as well as prolonged action up to 6-7 years (prototype 4-5 years), is used to treat a wide range of surfaces: hands, skin operating and injection fields of patients, gloves worn by the hands of medical personnel, hard-to-reach surfaces.

Claims (1)

A disinfectant containing octenidine dihydrochloride, propanol-1, propanol-2, characterized in that it additionally contains citric acid, lavender essential oil and water softened in the following ratio, in wt.%:
octenidine dihydrochloride 0.01-0.2 propanol-1 twenty propanol-2 fifty citric acid 0.001-0.002 lavender essential oil 0.2-0.5 softened water rest