RU2521499C2 - ВАКЦИНА, СОДЕРЖАЩАЯ ЭКСТРАКТ РИБОСОМНОГО БЕЛКА (RPE) И Th1- АКТИВИРУЮЩИЙ АДЪЮВАНТ - Google Patents
ВАКЦИНА, СОДЕРЖАЩАЯ ЭКСТРАКТ РИБОСОМНОГО БЕЛКА (RPE) И Th1- АКТИВИРУЮЩИЙ АДЪЮВАНТ Download PDFInfo
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- RU2521499C2 RU2521499C2 RU2010134427/10A RU2010134427A RU2521499C2 RU 2521499 C2 RU2521499 C2 RU 2521499C2 RU 2010134427/10 A RU2010134427/10 A RU 2010134427/10A RU 2010134427 A RU2010134427 A RU 2010134427A RU 2521499 C2 RU2521499 C2 RU 2521499C2
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
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- A—HUMAN NECESSITIES
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- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
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| US2192808P | 2008-01-18 | 2008-01-18 | |
| EP08100634.8 | 2008-01-18 | ||
| US61/021,928 | 2008-01-18 | ||
| EP08100634 | 2008-01-18 | ||
| PCT/EP2009/050334 WO2009090175A1 (en) | 2008-01-18 | 2009-01-14 | Vaccine comprising a ribosomal protein extract (rpe) and optionally a th1-promoting adjuvant |
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| RU2010134427A RU2010134427A (ru) | 2012-02-27 |
| RU2521499C2 true RU2521499C2 (ru) | 2014-06-27 |
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| SA110310855B1 (ar) | 2009-11-13 | 2014-09-16 | Laboratories Leti S L Unipersonal | استخدام مصدر l3 و/ أو l5 كلقاح أو كوسيلة تشخيصية لمرض طفيلي |
| SG190222A1 (en) | 2010-11-10 | 2013-06-28 | Leti Sl Lab | New adjuvant |
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| US6500437B1 (en) * | 1995-09-22 | 2002-12-31 | Corixa Corporation | Leishmania antigens for use in the therapy and diagnosis of leishmaniasis |
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| PT1141305E (pt) * | 1998-12-23 | 2006-10-31 | Leti Lab | Gene quimerico formado pelas sequencias de adn que codifica os determinantes antigenicos de quatro proteinas de l. infantum |
| ES2169995B1 (es) * | 2000-04-17 | 2003-12-01 | Leti Lab | Composicion a base de la proteina lip2a y su uso en la preparacion de un medicamento para suscitar una respuesta inmune contra un antigeno. |
| US20030072714A1 (en) * | 2001-10-12 | 2003-04-17 | Magill Alan J. | Microfluidized leishmania lysate and methods of making and using thereof |
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2015
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6500437B1 (en) * | 1995-09-22 | 2002-12-31 | Corixa Corporation | Leishmania antigens for use in the therapy and diagnosis of leishmaniasis |
Non-Patent Citations (1)
| Title |
|---|
| IBORRA S et al, Vaccination with the Leishmania infantum acidic ribosomal PO protein plus CpG oligodeoxynucleotides induces protection against cutaneous leishmaniasis in C57BL/6 mice but does not prevent progressive disease in BALB/c mice, Infect. Immun., 2005 sep., 73(9), abstract. IBORRA S et al, The Leishmania infantum acidic ribosomal protein PO administered as a DNA vaccine confers protective immunity to leishmania major infection in BALB/c mice, Infect. Immun., 2003 nov., 71(11), abstract. IBORRA S et al, The immunodominant T helper 2 (Th2) response elicited in BALB/c mice by the Leishmania LiP2a and LiP2b acidic ribosomal proteins cannot be reverted by strong Th1 inducers, Clin. Exp. Immunol., 2007 nov. 150(2) abstract. * |
Also Published As
| Publication number | Publication date |
|---|---|
| RU2010134427A (ru) | 2012-02-27 |
| JP2015180638A (ja) | 2015-10-15 |
| EP2231700B1 (en) | 2014-05-07 |
| PL2231700T3 (pl) | 2014-09-30 |
| JP2011509968A (ja) | 2011-03-31 |
| HRP20140447T1 (hr) | 2014-07-04 |
| MA32080B1 (fr) | 2011-02-01 |
| AP3007A (en) | 2014-10-31 |
| CN101977930A (zh) | 2011-02-16 |
| WO2009090175A1 (en) | 2009-07-23 |
| CA2712475A1 (en) | 2009-07-23 |
| EP2570427A1 (en) | 2013-03-20 |
| AP2010005333A0 (en) | 2010-08-31 |
| DK2231700T3 (da) | 2014-07-14 |
| AU2009204849A1 (en) | 2009-07-23 |
| PT2231700E (pt) | 2014-07-31 |
| CO6280495A2 (es) | 2011-05-20 |
| AU2009204849B2 (en) | 2013-10-03 |
| MX2010007831A (es) | 2011-06-20 |
| US20110020405A1 (en) | 2011-01-27 |
| HK1150291A1 (en) | 2011-11-18 |
| ES2486365T3 (es) | 2014-08-18 |
| ZA201005143B (en) | 2011-12-28 |
| BRPI0906787A2 (pt) | 2015-08-18 |
| EP2231700A1 (en) | 2010-09-29 |
| CN101977930B (zh) | 2014-12-17 |
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