CA2712475A1 - Vaccine comprising a ribosomal protein extract (rpe) and optionally a th1-promoting adjuvant - Google Patents

Vaccine comprising a ribosomal protein extract (rpe) and optionally a th1-promoting adjuvant Download PDF

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Publication number
CA2712475A1
CA2712475A1 CA2712475A CA2712475A CA2712475A1 CA 2712475 A1 CA2712475 A1 CA 2712475A1 CA 2712475 A CA2712475 A CA 2712475A CA 2712475 A CA2712475 A CA 2712475A CA 2712475 A1 CA2712475 A1 CA 2712475A1
Authority
CA
Canada
Prior art keywords
mice
lrpe
leishmania
vaccine
parasite
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2712475A
Other languages
English (en)
French (fr)
Inventor
Manuel Soto Alvarez
Daniel Ruiz Abanades
Carlos Alonso Bedate
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorios Leti SA
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2712475A1 publication Critical patent/CA2712475A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/002Protozoa antigens
    • A61K39/008Leishmania antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06Antimalarials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55561CpG containing adjuvants; Oligonucleotide containing adjuvants
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA2712475A 2008-01-18 2009-01-14 Vaccine comprising a ribosomal protein extract (rpe) and optionally a th1-promoting adjuvant Abandoned CA2712475A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US2192808P 2008-01-18 2008-01-18
EP08100634.8 2008-01-18
US61/021,928 2008-01-18
EP08100634 2008-01-18
PCT/EP2009/050334 WO2009090175A1 (en) 2008-01-18 2009-01-14 Vaccine comprising a ribosomal protein extract (rpe) and optionally a th1-promoting adjuvant

Publications (1)

Publication Number Publication Date
CA2712475A1 true CA2712475A1 (en) 2009-07-23

Family

ID=39471089

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2712475A Abandoned CA2712475A1 (en) 2008-01-18 2009-01-14 Vaccine comprising a ribosomal protein extract (rpe) and optionally a th1-promoting adjuvant

Country Status (19)

Country Link
US (1) US20110020405A1 (enExample)
EP (2) EP2231700B1 (enExample)
JP (2) JP2011509968A (enExample)
CN (1) CN101977930B (enExample)
AP (1) AP3007A (enExample)
AU (1) AU2009204849B2 (enExample)
BR (1) BRPI0906787A2 (enExample)
CA (1) CA2712475A1 (enExample)
CO (1) CO6280495A2 (enExample)
DK (1) DK2231700T3 (enExample)
ES (1) ES2486365T3 (enExample)
HR (1) HRP20140447T1 (enExample)
MA (1) MA32080B1 (enExample)
MX (1) MX2010007831A (enExample)
PL (1) PL2231700T3 (enExample)
PT (1) PT2231700E (enExample)
RU (1) RU2521499C2 (enExample)
WO (1) WO2009090175A1 (enExample)
ZA (1) ZA201005143B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SA110310855B1 (ar) 2009-11-13 2014-09-16 Laboratories Leti S L Unipersonal استخدام مصدر l3 و/ أو l5 كلقاح أو كوسيلة تشخيصية لمرض طفيلي
SG190222A1 (en) 2010-11-10 2013-06-28 Leti Sl Lab New adjuvant

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6500437B1 (en) * 1995-09-22 2002-12-31 Corixa Corporation Leishmania antigens for use in the therapy and diagnosis of leishmaniasis
PT1141305E (pt) * 1998-12-23 2006-10-31 Leti Lab Gene quimerico formado pelas sequencias de adn que codifica os determinantes antigenicos de quatro proteinas de l. infantum
ES2169995B1 (es) * 2000-04-17 2003-12-01 Leti Lab Composicion a base de la proteina lip2a y su uso en la preparacion de un medicamento para suscitar una respuesta inmune contra un antigeno.
US20030072714A1 (en) * 2001-10-12 2003-04-17 Magill Alan J. Microfluidized leishmania lysate and methods of making and using thereof

Also Published As

Publication number Publication date
RU2010134427A (ru) 2012-02-27
JP2015180638A (ja) 2015-10-15
EP2231700B1 (en) 2014-05-07
PL2231700T3 (pl) 2014-09-30
JP2011509968A (ja) 2011-03-31
HRP20140447T1 (hr) 2014-07-04
MA32080B1 (fr) 2011-02-01
AP3007A (en) 2014-10-31
CN101977930A (zh) 2011-02-16
WO2009090175A1 (en) 2009-07-23
EP2570427A1 (en) 2013-03-20
AP2010005333A0 (en) 2010-08-31
DK2231700T3 (da) 2014-07-14
AU2009204849A1 (en) 2009-07-23
PT2231700E (pt) 2014-07-31
CO6280495A2 (es) 2011-05-20
AU2009204849B2 (en) 2013-10-03
MX2010007831A (es) 2011-06-20
US20110020405A1 (en) 2011-01-27
HK1150291A1 (en) 2011-11-18
RU2521499C2 (ru) 2014-06-27
ES2486365T3 (es) 2014-08-18
ZA201005143B (en) 2011-12-28
BRPI0906787A2 (pt) 2015-08-18
EP2231700A1 (en) 2010-09-29
CN101977930B (zh) 2014-12-17

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20140110

FZDE Discontinued

Effective date: 20160819