RU2512933C2 - Способ лечения хронической сердечной недостаточности - Google Patents
Способ лечения хронической сердечной недостаточности Download PDFInfo
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- RU2512933C2 RU2512933C2 RU2010151470/14A RU2010151470A RU2512933C2 RU 2512933 C2 RU2512933 C2 RU 2512933C2 RU 2010151470/14 A RU2010151470/14 A RU 2010151470/14A RU 2010151470 A RU2010151470 A RU 2010151470A RU 2512933 C2 RU2512933 C2 RU 2512933C2
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- relaxin
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| US8415301B2 (en) | 2008-05-16 | 2013-04-09 | Corthera, Inc. | Method of treating dyspnea associated with acute heart failure by administering H2 relaxin |
| KR101800040B1 (ko) | 2010-03-10 | 2017-11-21 | 유니버시티 오브 플로리다 리서치 파운데이션, 인코포레이티드 | 릴랙신을 사용한 아쿠아포린의 조절 |
| WO2012072681A1 (en) * | 2010-12-01 | 2012-06-07 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Diagnostic and treatment of chronic heart failure |
| AU2012283235A1 (en) * | 2011-07-08 | 2014-01-09 | Bayer Intellectual Property Gmbh | Fusion proteins releasing Relaxin and uses thereof |
| AU2012291972B2 (en) * | 2011-08-04 | 2017-03-09 | Pharis Biotec Gmbh | Process for preparing human relaxin-2 |
| WO2013033324A2 (en) | 2011-08-31 | 2013-03-07 | University Of Florida Research Foundation, Inc. | Materials and methods for modulating activity of bone marrow derived cells |
| US20140364334A1 (en) * | 2011-12-21 | 2014-12-11 | Nuclea Biotechnologies, Inc. | Congestive heart failure biomarkers |
| JP6562632B2 (ja) | 2012-02-14 | 2019-08-21 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 心血管疾患および他の状態のためのパラクリン遺伝子の全身送達および制御された発現 |
| NZ710246A (en) * | 2013-01-25 | 2016-11-25 | Cardiorentis Ltd | Methods of treating cardiovasular indications |
| KR20160071472A (ko) * | 2013-11-07 | 2016-06-21 | 샹하이 헨그루이 파마수티컬 컴퍼니 리미티드 | 인간 릴렉신 유사체, 이의 약제학적 조성물 및 이의 약제학적 적용 |
| US10500227B2 (en) * | 2014-12-03 | 2019-12-10 | University Of Cincinnati | Bioactive gas-encapsulated echogenic liposomes and methods for treating cardiovascular disease |
| US11161891B2 (en) | 2015-12-09 | 2021-11-02 | The Scripps Research Institute | Relaxin immunoglobulin fusion proteins and methods of use |
| SG10201912034UA (en) | 2017-02-08 | 2020-02-27 | Bristol Myers Squibb Co | Modified relaxin polypeptides comprising a pharmacokinetic enhancer and uses thereof |
| CN107335051A (zh) * | 2017-08-18 | 2017-11-10 | 温州医科大学附属第医院 | 一种保护慢性心衰肾功能的药物组合物 |
| EP3883591B1 (en) * | 2018-11-20 | 2024-11-13 | Universität Heidelberg | Relaxin receptor 1 for use in treatment and prevention of heart failure |
| EP4058048A1 (en) * | 2019-11-16 | 2022-09-21 | Relaxera Pharmazeutische Gesellschaft mbH & Co. KG | Medical composition for treating cardiac wasting and cachexia |
| CN116406297A (zh) * | 2020-08-05 | 2023-07-07 | 阿斯克肋匹奥生物制药公司 | 治疗心脏疾患和充血性心力衰竭以及施用aav载体的方法 |
| RU2748529C1 (ru) * | 2020-09-01 | 2021-05-26 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр кардиологии" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ кардиологии" Минздрава России) | Способ определения этиологии хронической сердечной недостаточности |
| IL321288A (en) * | 2022-12-09 | 2025-08-01 | Astrazeneca Ab | Dosing regimens using fusions of relaxin heterodimers |
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| RU2213559C2 (ru) * | 2000-01-26 | 2003-10-10 | Тюменская государственная медицинская академия | Способ лечения больных хронической сердечной недостаточностью на фоне ишемической болезни сердца |
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| US5166191A (en) * | 1991-08-19 | 1992-11-24 | Genentech, Inc. | Use of relaxin in cardiovascular therapy |
| CA2165781C (en) | 1993-06-21 | 2007-02-13 | Tim Breece | Process for producing relaxin |
| US5811395A (en) | 1995-06-07 | 1998-09-22 | Medical University Of South Carolina | Relaxin analogs and derivatives methods and uses thereof |
| DE10155843A1 (de) * | 2000-11-16 | 2003-01-30 | Immundiagnostik Ag | Verfahren zur Prognose und Diagnose von Herzinsuffizienz |
| US20050113286A1 (en) * | 2002-03-18 | 2005-05-26 | Schreiner George F. | Methods for treating congestive heart failure |
| EP1729817B1 (en) * | 2004-03-30 | 2014-03-05 | Industry-Academic Cooperation Foundation | Gene delivery system containing relaxin gene and pharmaceutical composition using relaxin |
| WO2007008907A2 (en) * | 2005-07-11 | 2007-01-18 | Abbott Laboratories | Methods for determining how to treat congestive heart failure |
| CA2693651A1 (en) | 2007-07-12 | 2009-01-15 | Ronen Shemesh | Bioactive peptides and method of using same |
| US8415301B2 (en) * | 2008-05-16 | 2013-04-09 | Corthera, Inc. | Method of treating dyspnea associated with acute heart failure by administering H2 relaxin |
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| RU2213559C2 (ru) * | 2000-01-26 | 2003-10-10 | Тюменская государственная медицинская академия | Способ лечения больных хронической сердечной недостаточностью на фоне ишемической болезни сердца |
Non-Patent Citations (1)
| Title |
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| DSCHIETZIG T, et al. The pregnancy hormone relaxin is a player in human heart failureFASEB J. 2001 Oct;15(12):2187-95. DSCHIETZIG T, et al. Relaxin: a pregnancy hormone as central player of body fluid and circulation homeostasisCell Mol Life Sci. 2003 Apr;60(4):688-700. Кардиология. Национальное руководство. Под ред. Ю.Н.Беленкова и Р.Г.Оганова, М., "ГЭОТАР-Медиа", 2007, с.430,10-16-1041. O,NEIL et al. Recent Advances in the Diagnosis of Heart Failure. Current Cardiology Reports. May 2004, vol.6,No3,pp.205-210 * |
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| WO2009140657A3 (en) | 2010-01-07 |
| JP2017061453A (ja) | 2017-03-30 |
| JP2011520917A (ja) | 2011-07-21 |
| US20140005112A1 (en) | 2014-01-02 |
| AU2009246112A1 (en) | 2009-11-19 |
| EP3150219A1 (en) | 2017-04-05 |
| CN102026649A (zh) | 2011-04-20 |
| AU2009246112B2 (en) | 2013-05-02 |
| EP2288366A4 (en) | 2012-05-02 |
| CN104815319A (zh) | 2015-08-05 |
| CA2724535A1 (en) | 2009-11-19 |
| MX336145B (es) | 2016-01-08 |
| WO2009140657A2 (en) | 2009-11-19 |
| US20110144019A1 (en) | 2011-06-16 |
| US20160287672A1 (en) | 2016-10-06 |
| EP2288366A2 (en) | 2011-03-02 |
| BRPI0912559A2 (pt) | 2015-10-13 |
| RU2010151470A (ru) | 2012-06-27 |
| MX2010012502A (es) | 2011-04-11 |
| JP2014237648A (ja) | 2014-12-18 |
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