RU2493822C2 - Preparation for women's intimate hygiene - Google Patents

Abstract

FIELD: medicine.

SUBSTANCE: invention relates to cosmetic industry, in particular to preparation for women's intimate hygiene. Application of coniferous natural water extract as active component of preparation for women's intimate hygiene. Preparation for women's intimate hygiene, which contains coniferous natural water extract and soapy base, taken in specified ratio. Preparation for women's intimate hygiene for prevention and treatment of gynecological diseases, which contains coniferous natural water extract and soapy base, taken in specified ratio.

EFFECT: preparations are effective for women's intimate hygiene, have increased antibacterial activity, do not cause irritation on mucosa and skin, as well as have increased duration of influence of active components.

9 cl, 2 tbl, 3 ex

Description

FIELD OF THE INVENTION

The invention relates to the cosmetic industry, in particular, to a means for intimate hygiene of women, mainly to toilet soap, which contains only natural components, and as an active plant component, the coniferous natural water extract. The new tool provides normalization of the vaginal microflora, as it has antifungal, antimicrobial and antibacterial activity. The tool is devoid of side effects: does not cause irritation on the mucous membrane and skin. Toilet soap can also be used for hygienic purposes, to nourish and restore normal flora and improve the condition of the skin of hands, feet and face.

State of the art

Known means for intimate hygiene of women described previously in patents: RU 2149640 C1, 05.27.2000; RU 2008337 C1, 02.28.1994; US 6844303, January 18, 2005; RU 2243762 C1, 10.01.2005; RU 2201207 C1, 03/27/2003. The disadvantages of these agents include their inadequate protective function with respect to pathogenic microflora, adverse effects on the body of synthetic components introduced into formulations (dyes, plasticizers, obesity additives, synthetic surfactants and other synthetic components). When using such funds, serious problems can arise in women of the childbearing period during pregnancy, abortion, in the postpartum period, in people with weakened immunity.

The closest analogue of the present invention is a toilet soap according to patent RU 2354352 "Means for intimate hygiene of women", 05/10/2009. The soap contains a complex of fat-soluble bioactive substances (BAS) from pine and spruce needles: coniferous chlorophyll-carotene paste, or provitamin concentrate, or chlorophyll derivatives, as well as phytosterol. The disadvantages of this toilet soap include: the likelihood of using a synthetic soap base, the low content of phytosterol in the soap, which cannot be evenly distributed in a bar of soap in such quantities and in small doses does not improve the condition of the skin and mucous membrane. These biologically active substances were obtained by gasoline extraction of resinous substances from pine and spruce needles, i.e. these are components of the fat-soluble fraction, therefore, they do not contain many valuable biologically active substances of needles, soluble in water, but insoluble in hydrophobic solvents. The main part of micro- and macroelements, flavonoids, lignans, tannins, sugars, proteins and amino acids, those vitamins (C, PP, group B), which, when processing needles, pass into an aqueous solution and are not contained in any of the components indicated, are practically absent. in analogue.

At the same time, it is a complex of biologically active substances, soluble in water and included in the coniferous natural extract, that has the greatest protective effect for the skin and mucous membrane. Therefore, none of the known soaps containing only the fat-soluble components of the needles (the fat-soluble fraction) has an effect in women suffering from “vaginal dryness”, atrophic colpitis, which affects many women of different ages, especially the older age group. Serious problems also arise in women of the childbearing period during pregnancy, abortion, in the postpartum period, in people with weakened immune systems, for whom it is very important to restore the normal flora in the vagina.

SUMMARY OF THE INVENTION

The objective of the present invention is to expand the range of products for intimate hygiene of women with enhanced protective function against pathogenic microflora, restoring the normal flora of the skin and mucous membrane, stopping inflammatory diseases of the vaginal mucosa (atrophic colpitis).

Until now, the possibility of using coniferous water extract for the production of soap was not known, especially the use of this extract for intimate hygiene. Previously, ECN was not used in the composition of hygiene products also because the beneficial properties identified in this invention were not known. In addition, the use of ECN in soap was not considered due to the dark (almost black) color. ECH for many years was used only as a means for bathtubs (V. Yagodin. Fundamentals of chemistry and technology for processing green wood / Publishing House of Leningrad University. L., 1981, p. 91).

One of the objectives of the invention is solved in that the coniferous natural water extract is used as an active component of an agent for intimate hygiene of women. The possibility of using the extract as part of a hygiene product was never considered by anyone and was not obvious, due to the dark, almost black color of the extract, the strongly acid reaction of the product (pH = 4.5-5.5), as well as the ability to “stain” (stain ) the walls of the bathtub are dirty brown.

The second object of the present invention is a composition that contains an aqueous extract of coniferous natural (ECN) and a natural base (sodium salts of fatty acids and glycerin) in the following ratio of components, wt.%: ECN - 1.0-5.0; natural soap base - the rest is up to 100.

To increase the consumer properties of a soap product, to enhance the coniferous smell, fir essential oil in an amount of 0.01-0.05 mass% can be introduced into its composition.

For the purposes of the invention, natural coniferous extract is obtained by extraction of chopped coniferous paws of pine and spruce in hot water and / or with hot steam in an extractor at a temperature of 80-100 ° C for 3-4 hours, with a liquid module 4 ÷ 5, followed by separation (discharge) and filtering the aqueous extract and evaporating it to a dry matter content of 40 ÷ 50%.

The tool according to the present invention, preferably, is a toilet soap, and can also be made in the form of liquid soap, shower gel, gel or mousse for intimate hygiene.

The third object of the invention is a tool for the prevention and treatment of gynecological diseases on a soap basis with an aqueous extract of coniferous natural as an active component in the following ratio of components in wt.%: Natural coniferous extract - 1-5, soap base - the rest.

Disclosure of invention

Coniferous natural extract (ECN) was used and is used for the preparation of coniferous baths (manufacturers - Tikhvinsky Leskhimzavod LLC and other forest chemical enterprises), as a therapeutic drug for diseases of the central and peripheral nervous system, cardiovascular and rheumatic diseases. It is characterized by the following physical and chemical parameters: liquid of a dark brown (almost black) color, with a specific pleasant odor, density at 20 ° C of at least 1.225 g / cm ³ , content, wt.%: Essential oil - at least 0.5, dry substances - not less than 50, water-insoluble substances - not more than 15 from the dry residue, ash - not more than 5 from the dry residue (V. Yagodin. Fundamentals of chemistry and technology of processing green wood / Publishing House of Leningrad University. L., 1981, p. 91). ECH is added to the bathtub at a large dilution, while leaving a dark hard-to-wash trace on the walls of the bathtub. The claimed product containing ECN, when used, does not leave any dark marks on the skin, nor on clothing, nor on the walls of the bath.

Composition of water coniferous extract: water-soluble vitamins and provitins: C, groups B (B), B2, B6, PP), micro and macro elements (Na, Ca, K, Mn, Fe, Zn, etc.), proteins, amino acids, sugars, flavonoids, tannides, lignans, phytoncides (essential oils). Brownish-black liquid with a characteristic smell of coniferous essential oil (TU 81-05-97-70).

In the composition of the claimed funds the content of ECN is 1.0-5.0%. When the content in the means of ECN is less than 1%, its effectiveness decreases. When, for example, more than 5% ECN is introduced into the soap, the soap consistency deteriorates: ECN “sweats” out of the bar of soap, the marketability of the soap is lost.

Preparation of coniferous water extract: extraction of chopped pine and spruce needles with hot water or hot water with the addition of hot steam. The aqueous extract is drained, filtered off from mechanical impurities, then evaporated (preferably in a vacuum or on a rotary film evaporator) to a density of 1.19-1.225 g / cm ³ , the content of essential oil is at least 0.5%, dry matter is at least 50 %, ash content of solids not more than 5%, water-insoluble substances - not more than 15%.

Further, ECN according to the recipe is added to the soap base of a shower gel or gel or mousse for intimate hygiene or liquid soap and mixed. So, the production of toilet soap includes the preparation of a soap base (1), ECN (2) and their mixing in a prescription ratio (3):

1. Palm, coconut or other vegetable oil containing fatty acid esters is subjected to alkaline hydrolysis with an aqueous solution of sodium hydroxide at temperatures up to 100 ° C and stirring. The sodium salts of fatty acids and glycerin formed during hydrolysis are the soap base. Thus, glycerin is formed in the soap base during its preparation, while the glycerol usually formed during hydrolysis is distilled off from the sodium salts of fatty acids and sold as an independent commercial product, which affects the quality of the soap base.

In the soap base according to the invention, glycerol remains completely in the composition of the soap. At the same time, glycerin is a useful component of soap, it helps to soften and moisturize the skin, unlike soap without glycerin, it gives an excellent feeling on the skin. It should be noted that negative associations that occur when using synthetic detergents (dry skin, dermatitis, allergic reactions) are excluded. Glycerin obtained from natural palm and coconut oil softens and moisturizes the skin, rejuvenates the cells of the epidermis.

2. The production of ECN consists in extraction of chopped coniferous paws of pine and spruce in hot water and / or with hot steam in an extractor at a temperature of 80-100 ° C for 3-4 hours, with a liquid module 4-5, subsequent separation (discharge) and filtration water extract and its evaporation to a dry matter content of 40 ÷ 50%.

3. To a soap base heated to 60–70 ° C with stirring, add ECN in a prescription ratio (from 1 to 5%), and if necessary, 0.01 ÷ 0.05% of fir oil is added with stirring. The mixing process at the same temperature is carried out for 20 minutes The resulting homogeneous mass is poured into molds. The process for producing soap according to the invention is waste-free, without drains and emissions.

The advantages of such a soap: 100% natural sodium salts of fatty acids and glycerin isolated from natural vegetable oils do not contain synthetic surfactants and other synthetic additives. The soap perfectly moisturizes and creates a pleasant feeling on the skin, due to the high content of glycerin; pH - soaps slightly alkaline 8.0-9.0. Natural glycerin soap is not only beneficial for the skin, but also has other benefits. It is biodegradable, does not pollute the environment when used, does not harm nature.

The neutral smell of the base does not distort the smell of natural bioactive concentrate (ECN), which is part of this natural glycerin soap and nourishes the skin with vitamins and micronutrients from pine and spruce needles, which protects the skin from pathogenic microworld.

The tool according to the invention contains a multivitamin complex of needles that nourishes the skin, increases its elasticity and firmness; relieves inflammation, itching. The product has a weak tanning effect, collagen-strengthening, increasing the protective function of the skin and protecting it from pathogenic microworld. The tool is hypoallergenic.

According to clinical and microbiological studies, it was found that the tested product containing water coniferous extract has a pronounced antimicrobial effect. Antimicrobial activity in relation to staphylococci, streptococci, Gr (+) and Gr. (-) bacilli, yeast-like fungi, often the causative agents of infections of the external and internal genital tract. The tool with coniferous extract is recommended as an effective means of personal hygiene for women in all periods of life: the child-bearing age, the period of the menstrual cycle, the period of pregnancy, the postpartum period, the period of perimenopause. Marked disappearance of itching, unpleasant smell of secretions, a decrease in the number of secretions.

A positive effect of soap with coniferous extract was revealed in the group of women with atrophic calpitis: vaginal dryness disappeared, normal discharge appeared when using soap 2 times a day.

These advantages are the technical result of the claimed group of inventions.

Below the applicant presents examples of embodiments of the invention that will be clear to specialists in the field of hygiene products, but they are not intended to limit the scope of claims.

The implementation of the invention

The soap manufacturer is Phytolon-Med LLC (St. Petersburg). Soap is certified and registered by Rospotrebnadzor with the name soap toilet glycerin "Fitolon" ^R.

Example 1. For the manufacture of 10 kg of toilet soap according to the invention used 9.8 kg of soap base Crystal ORG obtained by alkaline hydrolysis of palm oil containing sodium salts of fatty acids and glycerin. The soap base from Crystal ORG natural vegetable oils was made using 100% organic oils (coconut, palm), does not contain chemical fertilizers and pesticides when growing oilseeds. Upon receipt and refining of oils, strict quality control tools are used, whitening and chemical distillation are not applied.

0.2 kg of ECN (2% by weight of soap) produced by TLHZ was added to the finished soap base, heated to a temperature of 70 ° C, with stirring for 10 minutes. The resulting mass was poured into elastic silicone molds at a temperature of 60 ° C, cooled to room temperature (15-25 ° C) for 12 hours, then removed from the molds and packaged in cardboard cases. The obtained pieces of glycerin toilet soap with ECN, weighing from 70 to 100 g (depending on the capacity of the mold), which received the name "Fitolon", were analyzed for compliance with GOST. Soap “Fitolon” is oval, homogeneous without cracks, opaque, dark brown in color, with a pleasant coniferous smell, hard to the touch, uniform in the section; The pH of a 1% aqueous solution is 9.0, the mass fraction of volatile substances is 28%.

Example 2. Soap weighing 1 kg was made analogously to example 1, but with the addition of fir essential oil (TEM) in the following formulation ratio of the components: soap base - 0.9500 kg (95%), ECN - 0.0499 kg (4.99% ), TEM - 0.0001 kg (0.01%). Soap was obtained: 10 pieces each weighing about 100 g. The soap corresponding to GOST was distributed between the employees of Fitolon-Med LLC, who used it to wash their face, hands, legs, head and for intimate hygiene. Received a positive assessment of the quality of soap. Employees noted the beneficial effects of soap on the scalp, face, hands and feet, as well as the skin of all parts of the body when washed in the shower and bath.

Example 3. Samples of soap with ECN (60 packs) with a weight of each piece 70 g, made according to example 1, were transferred for testing and clinical trials to the antenatal clinic of maternity hospital No. 6 in St. Petersburg (consultation of the maternity hospital named after Snegirev). The study involved 60 women from 23 to 67 years old, the average age is 37.7 years. Of these: 10 - pregnant women, 7 - in the postpartum period, 9 - premenopausal women with atrophic colpitis, 34 - gynecological patients in childbearing age. Each woman was offered an individual piece of the tested soap with ECN. The study took 2 to 4 weeks.

Before the start of testing and 2 weeks after using the soap, women were taken from the cervical canal. Microbiological control data was carried out by quantitative seeding and determining the nature of microorganisms, including those unfavorable from the point of view of the condition of the mucous membranes of the vagina and cervix (Staphylococcus spp., Streptococcus spp., Candida spp., Gram-positive and gram-negative bacilli).

Patients examined before and after using soap were taken smears on the flora, in which the main significant microorganisms were revealed after staining.

Seed before and after using the soap was studied by seeding on general, elective and differential diagnostic nutrient media, followed by microscopy of Gram stained smears. There was a clear quantitative decrease in staphylococci, streptococci and yeast-like fungi after using soaps with ECN.

Table 1 Name of microflora Seed Before the use of Phytolon soap After applying the Fitolon soap Staphylococci 1.0 × 10 ² - 1.0 × 10 ⁵ / tampon - 35.6% of patients 1.0 × 10 ² - 1.0 × 10 ⁵ / swab - 3.4% of patients Streptococcus 1.0 × 10 ² - 1.0 × 10 ⁵ / tampon - 18.6% of patients 1.0 × 10 ² -1.0 × 10 ⁵ / tampon - 1.7% of patients Gr (-) sticks 1.0 × 10 ² - 1.0 × 10 ⁵ / tampon - 25.4% of patients 1.0 × 10 ² / swab -5% of patients Gr (+) sticks 1.0 × 10 ² - 1.0 × 10 ⁵ / tampon - 39% of patients 1.0 × 10 ² / swab - 5% of patients Candida 1.0 × 10 ² - 1.0 × 10 ⁶ / swab - 61% of patients 1.0 × 10 ² / swab - 22% of patients

After using soap with ECN, all examined showed a significant decrease in the degree of microbial contamination and normalization of the vaginal microflora (Table 1).

All the tested women (60 people) noted that against the background of using soap, complaints such as itching disappeared, the number of secretions decreased, their unpleasant odor disappeared. This indicates that the normal vaginal microflora was restored with equalization of the pH of the medium, and an increase in the immune status. In the group with atrophic colpitis, the “dryness” of the vagina disappeared, normal discharge appeared when using soap no more than 1-2 times a day.

Sensory evaluation of soap is shown in table 2.

table 2 Name of indicator Positive rating Negative rating Smell Satisfied - 39 people. Not satisfied - 3, did not give an assessment - 18 people. Color 47 people Not happy - 0, but: very dark - 12 people, I want to get brighter - 1 person. Soap bar shape - oval Comfortable - 60 people. Not comfortable - 0; wish large pieces -5 people. Rinse off Increased - 3 people., Moderate - 43 people. Lowered - 14 people. Foam Thick - 23 people. Viscous - 4 people., Liquid - 1 people. Packaging Everything suits - 51 people. more colorful - 1, more fun - 1 person.

Patients have different taste preferences, therefore, the sensory assessment of soap is also different, but in general, the assessment was positive.

An important result of the present invention is the ability to eliminate the phenomenon of atrophic colpitis, restore the vaginal microflora, exclude conditionally pathogenic microflora with the help of means, without synthetic harmful medical preparations and herbal preparations.

The effectiveness of ECH toilet soap is obvious. Based on the results of the research, a report was compiled “Results of clinical testing of toilet soap with natural coniferous extract”, including the results of testing this soap in the antenatal clinic of maternity hospital No. 6 (consultation at the Snegirev maternity hospital, St. Petersburg). According to clinical and microbiological studies, it has been established that soap with ECN has a pronounced antimicrobial effect. High antimicrobial activity was noted in relation to staphylococci, streptococci, Gr (+) rods, Gr (-) rods, Candida, yeast-like fungi, which are often causative agents of infections of the external and internal genital tract. It was noted the disappearance of itching, unpleasant odor of secretions, the restoration of normoflora of the vagina with equalization of the pH of the medium, an increase in immune status, the disappearance of the “dryness” of the vagina, which, in turn, helps to normalize intimate relationships. It is proved that it is advisable to use soap for the prevention and treatment of atrophic colpitis and restore the composition of the vaginal microflora. The proposed soap is the only natural remedy for the restoration of the mucosa with atrophic colpitis, which does not have side effects. As follows from the report of experts, all existing treatment regimens relate to drugs that have side effects and do not lead to a complete restoration of normoflora. It is known that problems with pathogenic microflora, a violation of pH, “dryness” of the mucosa, unpleasant discharge and odor interfere with sexual activity. With normalization of the mucosa when using soap with ECN, sexual desire is also restored. According to the results of the research, soap with ECN is recommended as an effective means of personal hygiene for women in all periods of life: childbearing age, the period of the menstrual cycle, pregnancy, the postpartum period, as well as during menopause.

It was noted that soap can be successfully used for washing all parts of the body.

It turned out to be completely unobvious that ECN (acidic pH) should be introduced into the toilet soap having a pH of 8-9 (alkaline medium) to normalize the vaginal mucosa with atrophic colpitis, with conditionally pathogenic microflora to restore normal flora and, as a result, to normalize sexual life, improving intimate relationships. It was not obvious that soap of dark brown (black) color with ECN would be in demand by women. However, as follows from the questionnaires of the patients of female consultation No. 6 (see Table 2), the dark color of the soap does not cause a negative reaction, and even most women like it.

It has been clinically established that soap with ECN should be used 1-2 times a day, since soap with ECN has an increased duration of exposure. When using soap more than 2 times a day, the mucosa is again dried and returns to its original state, which was observed before the use of soap. Therefore, it is necessary and sufficient to use soap with ECN 1-2 times a day.

Claims (9)

1. The use of coniferous natural water extract as an active component of an agent for intimate hygiene of women. 2. A means for intimate hygiene of women based on plant components, characterized in that it contains coniferous natural water extract obtained from the processing of woody coniferous species, and a soap base containing sodium salts of fatty acids and glycerin obtained by alkaline hydrolysis of vegetable oil, in the following ratio of components, wt.%:
coniferous natural water extract 1-5 soap base rest 3. The tool according to claim 2, characterized in that it further comprises fir oil 0.01-0.10 wt.%. 4. The tool according to claim 2, characterized in that the coniferous natural extract obtained by extraction with hot water and / or hot steam of chopped coniferous paws of pine and spruce in an extractor at a temperature of 80-100 ° C for 3-4 hours, with a liquid module 4 ÷ 5, subsequent separation (discharge) and filtration of the aqueous extract and its evaporation to a dry matter content of 40 ÷ 50%. 5. The tool according to any one of claims 2 to 4, which is a toilet soap, liquid soap, shower gel, gel or mousse for intimate hygiene. 6. A means for intimate hygiene of women for the prevention and treatment of gynecological diseases based on plant components, characterized in that it contains coniferous natural water extract obtained from the processing of coniferous woody herbs, and a soap base containing sodium salts of fatty acids and glycerin obtained by alkaline hydrolysis of vegetable oil, in the following ratio of components, wt.%:
coniferous natural water extract 1-5 soap base rest 7. The tool according to claim 6, characterized in that it further comprises fir oil 0.01-0.10 wt.%. 8. The tool according to claim 6, characterized in that the natural coniferous extract obtained by extraction with hot water and / or hot steam of chopped pine and spruce coniferous paws in an extractor at a temperature of 80-100 ° C for 3-4 hours, with a liquid module 4 ÷ 5, subsequent separation (discharge) and filtration of the aqueous extract and its evaporation to a dry matter content of 40 ÷ 50%. 9. The tool according to any one of claims 6 to 8, which is a toilet soap, liquid soap, shower gel, gel or mousse for intimate hygiene.