RU2450263C2 - Биосенсорная система, обладающая повышенной стабильностью и гематокритной эффективностью - Google Patents

Биосенсорная система, обладающая повышенной стабильностью и гематокритной эффективностью Download PDF

Info

Publication number
RU2450263C2
RU2450263C2 RU2009115202/28A RU2009115202A RU2450263C2 RU 2450263 C2 RU2450263 C2 RU 2450263C2 RU 2009115202/28 A RU2009115202/28 A RU 2009115202/28A RU 2009115202 A RU2009115202 A RU 2009115202A RU 2450263 C2 RU2450263 C2 RU 2450263C2
Authority
RU
Russia
Prior art keywords
less
strip element
hematocrit
strip
sample
Prior art date
Application number
RU2009115202/28A
Other languages
English (en)
Russian (ru)
Other versions
RU2009115202A (ru
Inventor
Хуань-Пин У (US)
Хуань-Пин У
Кристин Д. НЕЛЬСОН (US)
Кристин Д. НЕЛЬСОН
Хоуп СПРАДЛИН (US)
Хоуп СПРАДЛИН
Эрик МОРЕР (US)
Эрик МОРЕР
Original Assignee
БАЙЕР ХЕЛТКЭА ЭлЭлСи
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by БАЙЕР ХЕЛТКЭА ЭлЭлСи filed Critical БАЙЕР ХЕЛТКЭА ЭлЭлСи
Publication of RU2009115202A publication Critical patent/RU2009115202A/ru
Application granted granted Critical
Publication of RU2450263C2 publication Critical patent/RU2450263C2/ru

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3274—Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/004—Enzyme electrodes mediator-assisted
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
    • C12Q1/006—Enzyme electrodes involving specific analytes or enzymes for glucose
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3273—Devices therefor, e.g. test element readers, circuitry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/817—Enzyme or microbe electrode

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Ecology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
RU2009115202/28A 2006-09-22 2007-09-09 Биосенсорная система, обладающая повышенной стабильностью и гематокритной эффективностью RU2450263C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84668806P 2006-09-22 2006-09-22
US60/846,688 2006-09-22

Publications (2)

Publication Number Publication Date
RU2009115202A RU2009115202A (ru) 2010-10-27
RU2450263C2 true RU2450263C2 (ru) 2012-05-10

Family

ID=38777711

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2009115202/28A RU2450263C2 (ru) 2006-09-22 2007-09-09 Биосенсорная система, обладающая повышенной стабильностью и гематокритной эффективностью

Country Status (12)

Country Link
US (6) US7862696B2 (OSRAM)
EP (2) EP2089531B1 (OSRAM)
JP (2) JP5395665B2 (OSRAM)
CN (1) CN101517093B (OSRAM)
BR (1) BRPI0717430A2 (OSRAM)
CA (1) CA2664186C (OSRAM)
ES (1) ES2748685T3 (OSRAM)
MX (1) MX2009002830A (OSRAM)
NO (1) NO20091572L (OSRAM)
RU (1) RU2450263C2 (OSRAM)
TW (1) TW200829214A (OSRAM)
WO (1) WO2008036516A1 (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2552942C2 (ru) * 2013-10-28 2015-06-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Уральский государственный экономический университет" (ФГБОУ ВПО "УрГЭУ") Устройство для неинвазивного потенциометрического определения оксидантной/антиоксидантной активности биологических тканей

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2383905T3 (es) 2004-12-13 2012-06-27 Bayer Healthcare, Llc Composiciones autolimitantes en términos de dimensión y dispositivos de ensayo para medir analitos en fluidos biológicos
US9636450B2 (en) 2007-02-19 2017-05-02 Udo Hoss Pump system modular components for delivering medication and analyte sensing at seperate insertion sites
US7826879B2 (en) 2006-02-28 2010-11-02 Abbott Diabetes Care Inc. Analyte sensors and methods of use
EP2089531B1 (en) 2006-09-22 2019-07-10 Ascensia Diabetes Care Holdings AG Biosensor system having enhanced stability and hematocrit performance
USD587142S1 (en) 2006-12-22 2009-02-24 Abbott Diabetes Care Inc. Sensors
WO2008154225A2 (en) * 2007-06-06 2008-12-18 Bayer Healthcare Llc Microdeposition system for a biosensor
CN107091870B (zh) * 2007-12-10 2019-10-08 安晟信医疗科技控股公司 确定分析物浓度的测量装置、生物传感器系统和方法
US8876755B2 (en) 2008-07-14 2014-11-04 Abbott Diabetes Care Inc. Closed loop control system interface and methods
EP2373805B1 (en) * 2008-12-08 2015-11-04 Bayer HealthCare LLC Low total salt reagent compositions and systems for biosensors
CN104825171B (zh) * 2009-02-26 2017-08-04 雅培糖尿病护理公司 改进的分析物传感器及其制造和使用方法
FI3912551T3 (fi) * 2009-02-26 2023-10-31 Abbott Diabetes Care Inc Parannettuja analyyttiantureita ja menetelmiä niiden valmistamiseksi ja käyttämiseksi
LT3689237T (lt) 2009-07-23 2021-09-27 Abbott Diabetes Care, Inc. Nuolatinio analitės matavimo sistema ir gamybos būdas
CA2767950C (en) * 2009-07-27 2019-11-12 Suresensors Ltd Improvements relating to sensor devices
US8691075B2 (en) * 2009-12-30 2014-04-08 Roche Diagnostics Operations, Inc. Method for measuring analyte concentration in a liquid sample
US9233788B2 (en) 2010-01-22 2016-01-12 Bayer Healthcare Llc Biosensor desiccant system having enhanced measurement performance
KR101783067B1 (ko) * 2010-01-22 2017-09-28 바이엘 헬쓰케어 엘엘씨 정확도 향상용 건조제
MX369764B (es) * 2010-06-07 2019-11-21 Ascensia Diabetes Care Holdings Ag Compensación basada en la pendiente que incluye señales de salida secundarias.
KR101749045B1 (ko) 2010-12-31 2017-06-20 시락 게엠베하 인터내셔날 고정확도 분석물 측정을 위한 시스템 및 방법
TWI565943B (zh) * 2011-07-22 2017-01-11 拜耳保健公司 具有增進測量性能之生物感測器乾燥劑系統
US20130052673A1 (en) * 2011-08-26 2013-02-28 Lifescan Scotland Ltd. Use of enzyme emulsion thickness to affect calibration code factors in test strip manufacturing
IN2014CN03415A (OSRAM) * 2011-11-18 2015-10-09 Murata Manufacturing Co
US9903830B2 (en) 2011-12-29 2018-02-27 Lifescan Scotland Limited Accurate analyte measurements for electrochemical test strip based on sensed physical characteristic(s) of the sample containing the analyte
US9535027B2 (en) * 2012-07-25 2017-01-03 Abbott Diabetes Care Inc. Analyte sensors and methods of using same
GB201223166D0 (en) * 2012-12-21 2013-02-06 Alere Switzerland Gmbh Test strip
US9097659B2 (en) 2013-03-14 2015-08-04 Bayer Healthcare Llc Maintaining electrode function during manufacture with a protective layer
JP6356707B2 (ja) 2013-03-15 2018-07-11 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 電気化学的測定中に高抗酸化物質レベルを検出してそれから分析物濃度をフェイルセイフする方法並びにそれを組み込んだデバイス、装置、及びシステム
EP3385707B1 (en) 2013-03-15 2024-07-10 Roche Diabetes Care GmbH Methods of scaling data used to construct biosensor algorithms
KR101730288B1 (ko) 2013-03-15 2017-04-25 에프. 호프만-라 로슈 아게 펄스화된 dc 블록을 갖는 테스트 시퀀스로 분석물질을 전기화학적으로 측정하는 방법들, 및 그것을 통합한 디바이스들, 장치들 및 시스템들
JP6352954B2 (ja) 2013-03-15 2018-07-04 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 電気化学的な分析物測定において回復パルスからの情報を使用する方法およびデバイス、装置とそれらを組み込むシステム
CA2900883C (en) 2013-03-15 2017-10-24 F. Hoffmann-La Roche Ag Methods of failsafing electrochemical measurements of an analyte as well as devices, apparatuses and systems incorporating the same
WO2014140173A1 (en) 2013-03-15 2014-09-18 Roche Diagnostics Gmbh Descriptor-based methods of electrochemically measuring an analyte as well as devices, apparatuses and systems incoporating the same
US9459231B2 (en) 2013-08-29 2016-10-04 Lifescan Scotland Limited Method and system to determine erroneous measurement signals during a test measurement sequence
US9243276B2 (en) 2013-08-29 2016-01-26 Lifescan Scotland Limited Method and system to determine hematocrit-insensitive glucose values in a fluid sample
WO2015137929A1 (en) * 2014-03-11 2015-09-17 Google Inc. Sensor
WO2016030346A2 (en) * 2014-08-25 2016-03-03 Roche Diagnostics Gmbh Interference compensating two electrodes test strip
WO2016127105A1 (en) 2015-02-05 2016-08-11 The Regents Of The University Of California Multiple-use renewable electrochemical sensors based on direct drawing of enzymatic inks
GB201507509D0 (en) * 2015-04-30 2015-06-17 Inside Biometrics Ltd Electrochemical Test Device
US20180263539A1 (en) * 2015-09-28 2018-09-20 The Regents Of The University Of California Wearable sensor arrays for in-situ body fluid analysis
JP6403653B2 (ja) * 2015-11-05 2018-10-10 シラグ・ゲーエムベーハー・インターナショナルＣｉｌａｇ ＧＭＢＨ Ｉｎｔｅｒｎａｔｉｏｎａｌ 高精度分析物測定用システム及び方法
CA3028348A1 (en) * 2016-07-12 2018-01-18 Ascensia Diabetes Care Holdings Ag Method for electrochemical analysis by use of alternating output signals from two electrodes
EP4481375A3 (en) 2016-10-05 2025-04-02 F. Hoffmann-La Roche AG Detection reagents and electrode arrangements for multi-analyte diagnostic test elements, as well as methods of using the same
JP6680702B2 (ja) * 2017-01-27 2020-04-15 シラグ・ゲーエムベーハー・インターナショナルＣｉｌａｇ ＧＭＢＨ Ｉｎｔｅｒｎａｔｉｏｎａｌ 高精度分析物測定用システム及び方法
CN110073206A (zh) * 2017-10-23 2019-07-30 B-生物有限公司 稳健地抗咖啡环效应的生物传感器
JP6609001B2 (ja) * 2018-06-04 2019-11-20 シラグ・ゲーエムベーハー・インターナショナル 高精度分析物測定用システム及び方法
US11344878B2 (en) * 2018-07-06 2022-05-31 Qorvo Us, Inc. Fluidic channels including conductivity sensor and methods of use thereof
US20210356462A1 (en) * 2018-11-20 2021-11-18 Essenlix Corporation Multiplex assay
US20230102721A1 (en) 2019-12-26 2023-03-30 I-Sens, Inc Novel organic electron transfer mediator and device comprising same
WO2022132963A1 (en) * 2020-12-15 2022-06-23 Abbott Diabetes Care Inc. Nad(p) depot for nad(p)-dependent enzyme-based sensors
WO2023009720A1 (en) * 2021-07-28 2023-02-02 Cleu Diagnostics, Llc Oxygen scavengers for electrochemical biosensors
JP7638430B1 (ja) * 2024-07-30 2025-03-03 キッコーマン株式会社 試薬組成物及びセンサ並びにその製造方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5997817A (en) * 1997-12-05 1999-12-07 Roche Diagnostics Corporation Electrochemical biosensor test strip
EP1074832A1 (en) * 1999-08-02 2001-02-07 Bayer Corporation Improved electrochemical-sensor design
WO2006042304A1 (en) * 2004-10-12 2006-04-20 Bayer Healthcare Llc Concentration determination in a diffusion barrier layer

Family Cites Families (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US36268A (en) * 1862-08-26 Improvement in horse-rakes
US3791933A (en) 1971-02-25 1974-02-12 Geomet Rapid methods for assay of enzyme substrates and metabolites
US3791988A (en) 1972-03-23 1974-02-12 Hoffmann La Roche Diagnostic test for glucose
GB1595616A (en) 1977-01-21 1981-08-12 Hitachi Ltd Air conditioning system
US5682884A (en) 1983-05-05 1997-11-04 Medisense, Inc. Strip electrode with screen printing
CA1219040A (en) 1983-05-05 1987-03-10 Elliot V. Plotkin Measurement of enzyme-catalysed reactions
US4746607A (en) 1985-02-07 1988-05-24 Eastman Kodak Company Use of substituted quinone electron transfer agents in analytical determinations
GB8626081D0 (en) 1986-10-31 1986-12-03 Unilever Plc Printing processes
US5126247A (en) 1988-02-26 1992-06-30 Enzymatics, Inc. Method, system and devices for the assay and detection of biochemical molecules
US5108564A (en) 1988-03-15 1992-04-28 Tall Oak Ventures Method and apparatus for amperometric diagnostic analysis
USRE36268E (en) 1988-03-15 1999-08-17 Boehringer Mannheim Corporation Method and apparatus for amperometric diagnostic analysis
US5128015A (en) 1988-03-15 1992-07-07 Tall Oak Ventures Method and apparatus for amperometric diagnostic analysis
EP0359831B2 (en) 1988-03-31 2007-06-20 Matsushita Electric Industrial Co., Ltd. Biosensor and process for its production
DE3826922A1 (de) 1988-08-09 1990-02-22 Boehringer Mannheim Gmbh Verfahren zur kolorimetrischen bestimmung eines analyten mittels enzymatischer oxidation
US5262035A (en) 1989-08-02 1993-11-16 E. Heller And Company Enzyme electrodes
US5320725A (en) 1989-08-02 1994-06-14 E. Heller & Company Electrode and method for the detection of hydrogen peroxide
US5264104A (en) 1989-08-02 1993-11-23 Gregg Brian A Enzyme electrodes
EP0505494B1 (en) 1989-12-15 1995-07-12 Boehringer Mannheim Corporation Redox mediator reagent and biosensor
US5288387A (en) 1990-06-12 1994-02-22 Daikin Industries, Ltd. Apparatus for maintaining the activity of an enzyme electrode
US5545519A (en) 1990-09-13 1996-08-13 Victoria University Of Manchester Electrolytic analytical methods
CA2050057A1 (en) 1991-03-04 1992-09-05 Adam Heller Interferant eliminating biosensors
US5393615A (en) 1994-02-03 1995-02-28 Miles Inc. Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof
US5762770A (en) 1994-02-21 1998-06-09 Boehringer Mannheim Corporation Electrochemical biosensor test strip
US5498542A (en) 1994-09-29 1996-03-12 Bayer Corporation Electrode mediators for regeneration of NADH and NADPH
US6153069A (en) 1995-02-09 2000-11-28 Tall Oak Ventures Apparatus for amperometric Diagnostic analysis
US5631863A (en) 1995-02-14 1997-05-20 Honeywell Inc. Random access memory cell resistant to radiation induced upsets
US5582697A (en) 1995-03-17 1996-12-10 Matsushita Electric Industrial Co., Ltd. Biosensor, and a method and a device for quantifying a substrate in a sample liquid using the same
US5620579A (en) 1995-05-05 1997-04-15 Bayer Corporation Apparatus for reduction of bias in amperometric sensors
US5520786A (en) 1995-06-06 1996-05-28 Bayer Corporation Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof
US5695947A (en) 1995-06-06 1997-12-09 Biomedix, Inc. Amperometric cholesterol biosensor
AUPN363995A0 (en) 1995-06-19 1995-07-13 Memtec Limited Electrochemical cell
US5628890A (en) 1995-09-27 1997-05-13 Medisense, Inc. Electrochemical sensor
US5631371A (en) 1995-11-22 1997-05-20 Bayer Corporation Method for the preparation of substituted 3-(phenylimino)-3H-phenothiazines and phenoxazines
US5708247A (en) 1996-02-14 1998-01-13 Selfcare, Inc. Disposable glucose test strips, and methods and compositions for making same
JP3370504B2 (ja) 1996-03-13 2003-01-27 松下電器産業株式会社 バイオセンサ
DE69730376T2 (de) * 1996-06-01 2005-08-18 Agfa-Gevaert (Photo)thermographisches Material mit verbesserten Transporteigenschaften
JPH10104192A (ja) * 1996-09-30 1998-04-24 Matsushita Electric Ind Co Ltd バイオセンサ
DK0958495T3 (da) 1997-02-06 2003-03-10 Therasense Inc In vitro analysand sensor med lille volumen
US5798031A (en) 1997-05-12 1998-08-25 Bayer Corporation Electrochemical biosensor
US6134461A (en) 1998-03-04 2000-10-17 E. Heller & Company Electrochemical analyte
US6475372B1 (en) 2000-02-02 2002-11-05 Lifescan, Inc. Electrochemical methods and devices for use in the determination of hematocrit corrected analyte concentrations
US6229390B1 (en) 1999-03-09 2001-05-08 Tripath Technology, Inc. Methods and apparatus for noise shaping a mixed signal power output
US6287451B1 (en) 1999-06-02 2001-09-11 Handani Winarta Disposable sensor and method of making
US6258229B1 (en) 1999-06-02 2001-07-10 Handani Winarta Disposable sub-microliter volume sensor and method of making
US6413398B1 (en) * 1999-09-13 2002-07-02 Her Majesty The Queen In Right Of Canada, As Represented By The Canadian Food Inspection Agency Method for electrochemical detection
CN1184472C (zh) * 1999-10-05 2005-01-12 松下电器产业株式会社 葡萄糖传感器
ES2238254T3 (es) 1999-12-27 2005-09-01 Matsushita Electric Industrial Co., Ltd. Biosensor.
WO2001073419A1 (en) 2000-03-29 2001-10-04 Matsushita Electric Industrial Co., Ltd. Biosensor
US6494873B2 (en) * 2000-03-31 2002-12-17 Sca Hygiene Products Absorbent article provided with a belt
JP4653870B2 (ja) * 2000-05-31 2011-03-16 株式会社テクノメデイカ コレステロール測定用センサ
US7163616B2 (en) 2001-09-14 2007-01-16 Bayer Corporation Reagents and methods for detecting analytes, and devices comprising reagents for detecting analytes
US7291256B2 (en) * 2002-09-12 2007-11-06 Lifescan, Inc. Mediator stabilized reagent compositions and methods for their use in electrochemical analyte detection assays
KR100554649B1 (ko) 2003-06-09 2006-02-24 주식회사 아이센스 전기화학적 바이오센서
TR201810169T4 (tr) * 2003-06-20 2018-08-27 Hoffmann La Roche Dar, homojen belirteç şeritlerinin üretilmesi için yöntem ve belirteç.
JP2005083965A (ja) * 2003-09-10 2005-03-31 Rohm Co Ltd 酵素機能電極及びコレステロールセンサ
JP4458802B2 (ja) 2003-10-02 2010-04-28 パナソニック株式会社 血液中のグルコースの測定方法およびそれに用いるセンサ
JP4839219B2 (ja) 2003-10-24 2011-12-21 バイエル・ヘルスケア・エルエルシー 酵素的電気化学的バイオセンサ
KR100814193B1 (ko) 2003-10-30 2008-03-17 아크레이 가부시키가이샤 바이오 센서 및 그 제조 방법
CA2548440C (en) 2003-12-04 2016-01-12 Matsushita Electric Industrial Co., Ltd. Method of measuring blood component, sensor used in the method, and measuring device
EP2574910B1 (en) 2003-12-04 2017-10-25 Panasonic Healthcare Holdings Co., Ltd. Hematocrit (Htc) measuring method
US8105478B2 (en) * 2004-01-29 2012-01-31 Siemens Aktiengesellschaft Method for measuring the concentration or change in concentration of a redox-active substance and corresponding device
US7138041B2 (en) 2004-02-23 2006-11-21 General Life Biotechnology Co., Ltd. Electrochemical biosensor by screen printing and method of fabricating same
JP4689601B2 (ja) 2004-04-19 2011-05-25 パナソニック株式会社 血液成分の測定方法、それに用いるバイオセンサおよび測定装置
KR20070114802A (ko) * 2005-03-04 2007-12-04 바이엘 헬쓰케어, 엘엘씨 전기화학적 바이오센서에서 효소 활성의 안정화
CA2890945C (en) * 2005-07-20 2016-11-29 Bayer Healthcare Llc Gated amperometry
JP5671205B2 (ja) * 2005-09-30 2015-02-18 バイエル・ヘルスケア・エルエルシー ゲート化ボルタンメトリー
UY29918A1 (es) 2005-11-14 2007-06-29 Bayer Healthcare Llc Reactivo para sensores de prueba que contiene polimeros de celulosa
EP2089531B1 (en) 2006-09-22 2019-07-10 Ascensia Diabetes Care Holdings AG Biosensor system having enhanced stability and hematocrit performance
CN101896618B (zh) 2007-12-10 2015-04-22 拜尔健康护理有限责任公司 检测分析物的试剂和方法
CN107091870B (zh) * 2007-12-10 2019-10-08 安晟信医疗科技控股公司 确定分析物浓度的测量装置、生物传感器系统和方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5997817A (en) * 1997-12-05 1999-12-07 Roche Diagnostics Corporation Electrochemical biosensor test strip
US6270637B1 (en) * 1997-12-05 2001-08-07 Roche Diagnostics Corporation Electrochemical biosensor test strip
EP1074832A1 (en) * 1999-08-02 2001-02-07 Bayer Corporation Improved electrochemical-sensor design
WO2006042304A1 (en) * 2004-10-12 2006-04-20 Bayer Healthcare Llc Concentration determination in a diffusion barrier layer

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2552942C2 (ru) * 2013-10-28 2015-06-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Уральский государственный экономический университет" (ФГБОУ ВПО "УрГЭУ") Устройство для неинвазивного потенциометрического определения оксидантной/антиоксидантной активности биологических тканей

Also Published As

Publication number Publication date
JP5395665B2 (ja) 2014-01-22
EP2089531A1 (en) 2009-08-19
US8702965B2 (en) 2014-04-22
JP5738914B2 (ja) 2015-06-24
JP2013145243A (ja) 2013-07-25
US9459229B2 (en) 2016-10-04
US7862696B2 (en) 2011-01-04
US20140061062A1 (en) 2014-03-06
US20080156662A1 (en) 2008-07-03
BRPI0717430A2 (pt) 2013-11-12
CA2664186C (en) 2021-02-23
EP2089531B1 (en) 2019-07-10
US20160084792A1 (en) 2016-03-24
MX2009002830A (es) 2009-05-28
CN101517093A (zh) 2009-08-26
US20110115504A1 (en) 2011-05-19
EP3543348A1 (en) 2019-09-25
HK1136605A1 (zh) 2010-07-02
US8728299B2 (en) 2014-05-20
JP2010504524A (ja) 2010-02-12
TW200829214A (en) 2008-07-16
US20160356738A1 (en) 2016-12-08
NO20091572L (no) 2009-04-21
RU2009115202A (ru) 2010-10-27
CA2664186A1 (en) 2008-03-27
US9239312B2 (en) 2016-01-19
US10261044B2 (en) 2019-04-16
CN101517093B (zh) 2016-01-06
ES2748685T3 (es) 2020-03-17
US20140305808A1 (en) 2014-10-16
EP3543348B1 (en) 2020-11-18
WO2008036516A1 (en) 2008-03-27

Similar Documents

Publication Publication Date Title
RU2450263C2 (ru) Биосенсорная система, обладающая повышенной стабильностью и гематокритной эффективностью
CN101073000B (zh) 扩散阻挡层中的浓度测定
AU2016202064B2 (en) Concentration determination in a diffusion barrier layer
HK1136605B (en) Biosensor system having enhanced stability and hematocrit performance
HK1112964B (en) Concentration determination in a diffusion barrier layer