RU2440352C2 - Ингибитор киназы - Google Patents
Ингибитор киназы Download PDFInfo
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- RU2440352C2 RU2440352C2 RU2009113615/04A RU2009113615A RU2440352C2 RU 2440352 C2 RU2440352 C2 RU 2440352C2 RU 2009113615/04 A RU2009113615/04 A RU 2009113615/04A RU 2009113615 A RU2009113615 A RU 2009113615A RU 2440352 C2 RU2440352 C2 RU 2440352C2
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| RU2656853C2 (ru) * | 2012-08-21 | 2018-06-07 | Ф. Хоффманн-Ля Рош Аг | Пирроло[2,3-в]пиразины в качестве ингибиторов syk |
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| ATE522536T1 (de) | 2008-02-25 | 2011-09-15 | Hoffmann La Roche | Pyrrolopyrazin-kinasehemmer |
| JP5368485B2 (ja) | 2008-02-25 | 2013-12-18 | エフ．ホフマン−ラ ロシュ アーゲー | ピロロピラジンキナーゼインヒビター |
| MX2010008308A (es) * | 2008-03-10 | 2010-08-11 | Sanofi Aventis | Tratamiento para trastornos relacionados con los ojos. |
| FR2929851B1 (fr) * | 2008-04-09 | 2012-11-30 | Centre Nat Rech Scient | Molecules inhibant une voie metabolique impliquant la proteine tyrosine kinase syk et procede d'identification de ces molecules |
| PA8851701A1 (es) | 2008-12-03 | 2010-07-27 | Sanofi Aventis | Tratamiento para la glomerulonefritis |
| EP2373655A1 (en) | 2008-12-04 | 2011-10-12 | Sanofi | Crystalline forms |
| TW201034675A (en) * | 2008-12-18 | 2010-10-01 | Sanofi Aventis | Method for treating macular degeneration |
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| AR075869A1 (es) * | 2009-03-19 | 2011-05-04 | Sanofi Aventis | Sintesis de azaindoles |
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| US8481541B2 (en) | 2010-03-22 | 2013-07-09 | Hoffmann-La Roche Inc. | Pyrrolopyrazine kinase inhibitors |
| US8518945B2 (en) | 2010-03-22 | 2013-08-27 | Hoffmann-La Roche Inc. | Pyrrolopyrazine kinase inhibitors |
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| CN102906095A (zh) | 2010-05-20 | 2013-01-30 | 弗·哈夫曼-拉罗切有限公司 | 作为syk和jak抑制剂的吡咯并吡嗪衍生物 |
| EP2441755A1 (en) | 2010-09-30 | 2012-04-18 | Almirall, S.A. | Pyridine- and isoquinoline-derivatives as Syk and JAK kinase inhibitors |
| EP2489663A1 (en) | 2011-02-16 | 2012-08-22 | Almirall, S.A. | Compounds as syk kinase inhibitors |
| JP6026525B2 (ja) | 2011-06-22 | 2016-11-16 | 武田薬品工業株式会社 | 置換６−アザ−イソインドリン−１−オン誘導体 |
| NZ715747A (en) | 2013-07-31 | 2017-03-31 | Gilead Sciences Inc | Syk inhibitors |
| US20220143049A1 (en) | 2019-03-21 | 2022-05-12 | Onxeo | A dbait molecule in combination with kinase inhibitor for the treatment of cancer |
| EP4054579A1 (en) | 2019-11-08 | 2022-09-14 | Institut National de la Santé et de la Recherche Médicale (INSERM) | Methods for the treatment of cancers that have acquired resistance to kinase inhibitors |
| WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
| CN116969927B (zh) * | 2023-06-07 | 2024-03-19 | 中南民族大学 | 一种从荜茇中提取分离的化合物及该化合物在制备抗炎药物中的应用 |
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| US5397787A (en) * | 1992-12-23 | 1995-03-14 | Farmitalia Carlo Erba S.R.L. | Vinylene-azaindole derivatives |
| RU2004101408A (ru) * | 2001-06-21 | 2005-04-20 | Авентис Фарма Лимитед (Gb) | Азаиндолы |
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| US3992392A (en) | 1973-04-27 | 1976-11-16 | The Ohio State University Research Foundation | Synthesis of indoles from anilines and intermediates therein |
| SE9100920D0 (sv) | 1991-03-27 | 1991-03-27 | Astra Ab | New active compounds |
| JPH10510510A (ja) | 1994-06-09 | 1998-10-13 | スミスクライン・ビーチャム・コーポレイション | エンドセリン受容体拮抗物質 |
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| RU2656853C2 (ru) * | 2012-08-21 | 2018-06-07 | Ф. Хоффманн-Ля Рош Аг | Пирроло[2,3-в]пиразины в качестве ингибиторов syk |
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