RU2424320C2 - Устройство и способ измерения концентраций молекул через барьер - Google Patents

Устройство и способ измерения концентраций молекул через барьер Download PDF

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RU2424320C2
RU2424320C2 RU2007107810/13A RU2007107810A RU2424320C2 RU 2424320 C2 RU2424320 C2 RU 2424320C2 RU 2007107810/13 A RU2007107810/13 A RU 2007107810/13A RU 2007107810 A RU2007107810 A RU 2007107810A RU 2424320 C2 RU2424320 C2 RU 2424320C2
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molecules
measuring
gel
target objects
glucose
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RU2007107810/13A
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English (en)
Russian (ru)
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RU2007107810A (ru
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Иван Е. МОДРОВИЧ (US)
Иван Е. МОДРОВИЧ
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Иван Е. МОДРОВИЧ
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00Apparatus for enzymology or microbiology
    • C12M1/34Measuring or testing with condition measuring or sensing means, e.g. colony counters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1486Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/41Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/411Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00Apparatus for enzymology or microbiology

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Optics & Photonics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Vascular Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Sustainable Development (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Emergency Medicine (AREA)
  • Analytical Chemistry (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
RU2007107810/13A 2004-08-05 2005-08-05 Устройство и способ измерения концентраций молекул через барьер RU2424320C2 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US59889604P 2004-08-05 2004-08-05
US60/598,896 2004-08-05
US11/190,834 US7595170B2 (en) 2004-08-05 2005-07-28 Apparatus and method for measuring concentrations of molecules through a barrier
US11/190,834 2005-07-28

Related Child Applications (1)

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RU2011110197/10A Division RU2011110197A (ru) 2004-08-05 2011-03-17 Устройство и способ измерения концентраций молекул через барьер

Publications (2)

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RU2007107810A RU2007107810A (ru) 2008-09-10
RU2424320C2 true RU2424320C2 (ru) 2011-07-20

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RU2007107810/13A RU2424320C2 (ru) 2004-08-05 2005-08-05 Устройство и способ измерения концентраций молекул через барьер
RU2011110197/10A RU2011110197A (ru) 2004-08-05 2011-03-17 Устройство и способ измерения концентраций молекул через барьер

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Country Status (8)

Country Link
US (3) US7595170B2 (zh)
EP (2) EP2301437A2 (zh)
JP (1) JP5096145B2 (zh)
KR (1) KR101206664B1 (zh)
CN (1) CN101432416B (zh)
MX (1) MX2007001326A (zh)
RU (2) RU2424320C2 (zh)
WO (1) WO2006017728A2 (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7595170B2 (en) * 2004-08-05 2009-09-29 Modrovich Ivan E Apparatus and method for measuring concentrations of molecules through a barrier
WO2009062038A2 (en) * 2007-11-07 2009-05-14 Board Of Regents, The University Of Texas System Method for performing electrostatically induced redox chemistry on a dielectric surface
CN107389935A (zh) * 2017-07-31 2017-11-24 重庆微奥云生物技术有限公司 一种病毒抗原的检测方法及病毒抗原探针包被方法
CN107271497A (zh) * 2017-07-31 2017-10-20 重庆微奥云生物技术有限公司 一种蛋白质抗体检测系统及检测质量控制方法
CN107271690A (zh) * 2017-07-31 2017-10-20 重庆微奥云生物技术有限公司 一种蛋白质抗原检测系统及检测质量控制方法
CN107367613A (zh) * 2017-07-31 2017-11-21 重庆微奥云生物技术有限公司 一种细菌抗原的检测方法及细菌抗原探针包被方法

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2482773A (en) * 1946-10-23 1949-09-27 Thomas G Hieronymus Detection of emanations from materials and measurement of the volumes thereof
US3689393A (en) * 1969-10-20 1972-09-05 Merlin Davis Blood diagnostic instruments
US4317879A (en) * 1979-05-07 1982-03-02 Airco, Inc. Glucose analyzer membrane containing immobilized glucose oxidase
US4436094A (en) * 1981-03-09 1984-03-13 Evreka, Inc. Monitor for continuous in vivo measurement of glucose concentration
US4882423A (en) * 1984-10-02 1989-11-21 Calpis Food Industry Substance-conjugated complement component C1q
US4713347A (en) * 1985-01-14 1987-12-15 Sensor Diagnostics, Inc. Measurement of ligand/anti-ligand interactions using bulk conductance
JPS61271460A (ja) * 1985-05-28 1986-12-01 Olympus Optical Co Ltd 免疫学的分析方法
US5157019A (en) * 1986-03-18 1992-10-20 Monsanto Company Serine protease inhibitors
USH431H (en) * 1986-11-28 1988-02-02 The United States Of America As Represented By The Secretary Of The Army Portable laboratory for detection and monitoring of hazardous chemicals
US6306594B1 (en) * 1988-11-14 2001-10-23 I-Stat Corporation Methods for microdispensing patterened layers
US5212050A (en) * 1988-11-14 1993-05-18 Mier Randall M Method of forming a permselective layer
JPH02180243A (ja) * 1988-12-29 1990-07-13 Shimadzu Corp 医用計測装置
WO1992000525A1 (en) * 1990-06-29 1992-01-09 E.I. Du Pont De Nemours And Company Assay for detecting and/or quantifying a mammalian antibody response to epstein-barr virus membrane antigen
US5705399A (en) * 1994-05-20 1998-01-06 The Cooper Union For Advancement Of Science And Art Sensor and method for detecting predetermined chemical species in solution
US6143247A (en) * 1996-12-20 2000-11-07 Gamera Bioscience Inc. Affinity binding-based system for detecting particulates in a fluid
US6110660A (en) * 1995-08-20 2000-08-29 The European Institute Of Science Ab Procedure for quantitative and qualitative determination of chemical substances, based on molecular recognition and measurement of magnetic permeability
US5804436A (en) * 1996-08-02 1998-09-08 Axiom Biotechnologies, Inc. Apparatus and method for real-time measurement of cellular response
JPH1071268A (ja) 1996-08-29 1998-03-17 Omron Corp 生体情報占い装置及び生体情報占い方法
US6120460A (en) * 1996-09-04 2000-09-19 Abreu; Marcio Marc Method and apparatus for signal acquisition, processing and transmission for evaluation of bodily functions
DK0925494T3 (da) * 1996-09-04 2002-07-01 Scandinavian Micro Biodevices Mikrostrømningssystem til partikelseparation og analyse
US5830139A (en) * 1996-09-04 1998-11-03 Abreu; Marcio M. Tonometer system for measuring intraocular pressure by applanation and/or indentation
US6022948A (en) * 1996-09-17 2000-02-08 Washington University Method of cell surface activation and inhibition
US6413786B1 (en) * 1997-01-23 2002-07-02 Union Biometrica Technology Holdings, Inc. Binding assays using optical resonance of colloidal particles
US6100045A (en) * 1997-02-10 2000-08-08 Dsm N.V. Detection of analytes using electrochemistry
US6043024A (en) * 1997-04-18 2000-03-28 Abbott Laboratories Use of one-dimensional nuclear magnetic resonance to identify ligands to target biomolecules
US6699724B1 (en) * 1998-03-11 2004-03-02 Wm. Marsh Rice University Metal nanoshells for biosensing applications
US6322963B1 (en) * 1998-06-15 2001-11-27 Biosensor Systems Design., Inc. Sensor for analyte detection
US6321588B1 (en) * 1998-09-11 2001-11-27 Femtometrics, Inc. Chemical sensor array
US6343225B1 (en) 1999-09-14 2002-01-29 Implanted Biosystems, Inc. Implantable glucose sensor
US6919202B2 (en) * 2000-04-07 2005-07-19 The United States Of America, As Represented By The Secretary Of Agriculture Utilization of invertebrate learning for flexible and sensitive monitoring and identification of chemicals
EP1423091A4 (en) * 2001-08-10 2005-07-20 Univ California SENSITIVE AND RAPID DETECTION OF PATHOGENIC ORGANISMS AND TOXINS USING FLUORESCENT POLYMER LIPIDS
US20030159523A1 (en) * 2001-10-29 2003-08-28 Renfro William Leonard Contraband detection system
JP2003139676A (ja) * 2001-10-31 2003-05-14 Japan Science & Technology Corp Dnaスピンマッピング・医療方法及びその装置
US6784854B1 (en) * 2002-03-25 2004-08-31 Spatial Dynamics, Ltd. Dielectric detection through conductive metal
JP2006501860A (ja) * 2002-05-22 2006-01-19 プラティパス テクノロジーズ エルエルシー 細胞をアッセイするための基体、装置および方法
US7393693B2 (en) * 2002-05-31 2008-07-01 Agilent Technologies, Inc. Methods and procedures for stabilization and performance optimization of multi-layer sol-gel chemical and biochemical sensors
US7595170B2 (en) * 2004-08-05 2009-09-29 Modrovich Ivan E Apparatus and method for measuring concentrations of molecules through a barrier

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CARBECK et al «Protein charge ladders, capillary electrophoresis, and the role of electrostatics in biomolecular recognition» Acc Chem Res., 1998, Vol. 31. pp 343-350. *

Also Published As

Publication number Publication date
RU2011110197A (ru) 2012-09-27
WO2006017728A2 (en) 2006-02-16
KR101206664B1 (ko) 2012-11-29
US20090311670A1 (en) 2009-12-17
JP5096145B2 (ja) 2012-12-12
KR20070060073A (ko) 2007-06-12
US20060030031A1 (en) 2006-02-09
US7595170B2 (en) 2009-09-29
MX2007001326A (es) 2007-06-25
CN101432416B (zh) 2013-07-31
EP2301437A2 (en) 2011-03-30
JP2008517249A (ja) 2008-05-22
EP1778830A2 (en) 2007-05-02
WO2006017728A3 (en) 2009-04-02
CN101432416A (zh) 2009-05-13
RU2007107810A (ru) 2008-09-10
US20100041021A1 (en) 2010-02-18
EP1778830A4 (en) 2011-12-07

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Effective date: 20120806