RU2422510C2 - Способ получения пуриновых рибонуклеозидов и рибонуклеотидов - Google Patents

Способ получения пуриновых рибонуклеозидов и рибонуклеотидов Download PDF

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RU2422510C2
RU2422510C2 RU2008138616/10A RU2008138616A RU2422510C2 RU 2422510 C2 RU2422510 C2 RU 2422510C2 RU 2008138616/10 A RU2008138616/10 A RU 2008138616/10A RU 2008138616 A RU2008138616 A RU 2008138616A RU 2422510 C2 RU2422510 C2 RU 2422510C2
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gene
strain
pcr
bacterium
seq
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RU2008138616/10A
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English (en)
Russian (ru)
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RU2008138616A (ru
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Сергей Викторович Гронский (RU)
Сергей Викторович Гронский
Дмитрий Владимирович Романенков (RU)
Дмитрий Владимирович Романенков
Наталия Павловна Закатаева (RU)
Наталия Павловна Закатаева
Такаюки АСАХАРА (JP)
Такаюки АСАХАРА
Original Assignee
Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ)
Аджиномото Ко., Инк.
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Application filed by Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ), Аджиномото Ко., Инк. filed Critical Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ)
Priority to RU2008138616/10A priority Critical patent/RU2422510C2/ru
Priority to JP2011513790A priority patent/JP5488594B2/ja
Priority to CN200980138368.1A priority patent/CN102171346B/zh
Priority to PCT/JP2009/067447 priority patent/WO2010038903A1/en
Publication of RU2008138616A publication Critical patent/RU2008138616A/ru
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Publication of RU2422510C2 publication Critical patent/RU2422510C2/ru

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
RU2008138616/10A 2008-09-30 2008-09-30 Способ получения пуриновых рибонуклеозидов и рибонуклеотидов RU2422510C2 (ru)

Priority Applications (4)

Application Number Priority Date Filing Date Title
RU2008138616/10A RU2422510C2 (ru) 2008-09-30 2008-09-30 Способ получения пуриновых рибонуклеозидов и рибонуклеотидов
JP2011513790A JP5488594B2 (ja) 2008-09-30 2009-09-30 プリンリボヌクレオシド及びリボヌクレオチドの製造方法
CN200980138368.1A CN102171346B (zh) 2008-09-30 2009-09-30 产生嘌呤核糖核苷和核糖核苷酸的方法
PCT/JP2009/067447 WO2010038903A1 (en) 2008-09-30 2009-09-30 A method for producing purine ribonucleosides and ribonucleotides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2008138616/10A RU2422510C2 (ru) 2008-09-30 2008-09-30 Способ получения пуриновых рибонуклеозидов и рибонуклеотидов

Publications (2)

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RU2008138616A RU2008138616A (ru) 2010-04-10
RU2422510C2 true RU2422510C2 (ru) 2011-06-27

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RU2008138616/10A RU2422510C2 (ru) 2008-09-30 2008-09-30 Способ получения пуриновых рибонуклеозидов и рибонуклеотидов

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JP (1) JP5488594B2 (enExample)
CN (1) CN102171346B (enExample)
RU (1) RU2422510C2 (enExample)
WO (1) WO2010038903A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2542387C1 (ru) * 2013-09-27 2015-02-20 Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов" (ФГУП "ГосНИИгенетика") БАКТЕРИЯ Bacillus subtilis, ПРОДУЦИРУЮЩАЯ 5`-АМИНОИМИДАЗОЛ-4-КАРБОКСАМИДРИБОЗИД (АИКАР), И СПОСОБ МИКРОБИОЛОГИЧЕСКОГО СИНТЕЗА АИКАР ПУТЕМ КУЛЬТИВИРОВАНИЯ ТАКОЙ БАКТЕРИИ
WO2020071538A1 (en) 2018-10-05 2020-04-09 Ajinomoto Co., Inc. Method for producing target substance by bacterial fermentation

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103150487B (zh) * 2012-11-29 2016-05-11 扬州大学 一种构建鸡肌肉肌苷酸合成途径相关关键酶基因网络调控方法
US20160017339A1 (en) * 2013-03-14 2016-01-21 The Regents Of The University Of California Non-co2 evolving metabolic pathway for chemical production
US9518278B2 (en) 2013-03-14 2016-12-13 The Regents Of The University Of California Recombinant microorganisms having a methanol elongation cycle (MEC)
CN103146786A (zh) * 2013-03-25 2013-06-12 天津科技大学 一种采用梯度pH顺序控制发酵生产腺苷的方法
CN105670979B (zh) * 2016-04-26 2019-03-26 南京工业大学 一种核苷磷酸化酶、编码基因及其高产菌株和应用
CN112574934B (zh) * 2020-10-12 2022-05-06 廊坊梅花生物技术开发有限公司 高产鸟苷的工程菌及其构建方法与应用
CN112592881B (zh) * 2021-02-25 2021-06-11 中国科学院天津工业生物技术研究所 用于高效外源蛋白表达和高密度培养的工程枯草芽孢杆菌
CN115725486B (zh) * 2022-08-18 2025-07-22 江南大学 一种利用甲醇为碳源的苏云金芽孢杆菌及其应用
CN115851855A (zh) 2022-08-24 2023-03-28 凯莱英医药集团（天津）股份有限公司 酶催化合成嘌呤核苷的方法及组合物

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1170371A1 (en) * 2000-07-07 2002-01-09 Ajinomoto Co., Ltd. Phosphohexuloisomerase and gene therefor
EP1700910A2 (en) * 2005-03-10 2006-09-13 Ajinomoto Co., Inc. Purine-derived substance-producing Bacillus and a method for producing purine-derived substance therewith
WO2008084629A1 (en) * 2006-12-22 2008-07-17 Ajinomoto Co., Inc. A method for producing purine nucleosides and nucleotides by fermentation using a bacterium belonging to the genus escherichia or bacillus

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1170371A1 (en) * 2000-07-07 2002-01-09 Ajinomoto Co., Ltd. Phosphohexuloisomerase and gene therefor
EP1700910A2 (en) * 2005-03-10 2006-09-13 Ajinomoto Co., Inc. Purine-derived substance-producing Bacillus and a method for producing purine-derived substance therewith
WO2008084629A1 (en) * 2006-12-22 2008-07-17 Ajinomoto Co., Inc. A method for producing purine nucleosides and nucleotides by fermentation using a bacterium belonging to the genus escherichia or bacillus

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
KATO NOBUO ET AL: "The physiological role of the ribulose monophosphate pathway in bacteria and archaea" BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2006, v.70, no.1, p.10-21. ORITA IZUMI ET AL: "The ribulose monophosphate pathway substitutes for the missing pentose phosphate pathway in the archaeon Thermococcus kodakaraensis" JOURNAL OF BACTERIOLOGY, 2006, v.188, no.13, p.4698-4704. *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2542387C1 (ru) * 2013-09-27 2015-02-20 Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов" (ФГУП "ГосНИИгенетика") БАКТЕРИЯ Bacillus subtilis, ПРОДУЦИРУЮЩАЯ 5`-АМИНОИМИДАЗОЛ-4-КАРБОКСАМИДРИБОЗИД (АИКАР), И СПОСОБ МИКРОБИОЛОГИЧЕСКОГО СИНТЕЗА АИКАР ПУТЕМ КУЛЬТИВИРОВАНИЯ ТАКОЙ БАКТЕРИИ
WO2020071538A1 (en) 2018-10-05 2020-04-09 Ajinomoto Co., Inc. Method for producing target substance by bacterial fermentation

Also Published As

Publication number Publication date
RU2008138616A (ru) 2010-04-10
CN102171346B (zh) 2014-09-03
CN102171346A (zh) 2011-08-31
JP5488594B2 (ja) 2014-05-14
JP2012503973A (ja) 2012-02-16
WO2010038903A1 (en) 2010-04-08

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