RU2404190C2 - Деамидированный интерферон-бета - Google Patents
Деамидированный интерферон-бета Download PDFInfo
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- RU2404190C2 RU2404190C2 RU2007121515/04A RU2007121515A RU2404190C2 RU 2404190 C2 RU2404190 C2 RU 2404190C2 RU 2007121515/04 A RU2007121515/04 A RU 2007121515/04A RU 2007121515 A RU2007121515 A RU 2007121515A RU 2404190 C2 RU2404190 C2 RU 2404190C2
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- Prior art keywords
- inf
- deamidated
- protein
- interferon
- protein analogue
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- 239000011780 sodium chloride Substances 0.000 description 1
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- 239000000243 solution Substances 0.000 description 1
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- 238000004611 spectroscopical analysis Methods 0.000 description 1
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Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/565—IFN-beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Virology (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62683704P | 2004-11-10 | 2004-11-10 | |
| US60/626,837 | 2004-11-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2007121515A RU2007121515A (ru) | 2008-12-20 |
| RU2404190C2 true RU2404190C2 (ru) | 2010-11-20 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2007121515/04A RU2404190C2 (ru) | 2004-11-10 | 2005-11-10 | Деамидированный интерферон-бета |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US7595040B2 (https=) |
| EP (1) | EP1809662B1 (https=) |
| JP (1) | JP4891250B2 (https=) |
| KR (1) | KR101330626B1 (https=) |
| CN (1) | CN101056890B (https=) |
| AT (1) | ATE415421T1 (https=) |
| AU (1) | AU2005304486B2 (https=) |
| BR (1) | BRPI0517697A (https=) |
| CA (1) | CA2587061C (https=) |
| DE (1) | DE602005011321D1 (https=) |
| ES (1) | ES2318575T3 (https=) |
| MX (1) | MX2007004990A (https=) |
| PL (1) | PL1809662T3 (https=) |
| PT (1) | PT1809662E (https=) |
| RU (1) | RU2404190C2 (https=) |
| WO (1) | WO2006053134A2 (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2739261C1 (ru) * | 2019-12-31 | 2020-12-22 | Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) | Способ количественного определения антипролиферативной активности интерферона-бета человека |
| RU2812047C1 (ru) * | 2020-04-29 | 2024-01-22 | Абион Инк. | Вариант интерферона-бета человека с двойной мутацией и способ улучшения стабильности варианта интерферона-бета человека |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030190307A1 (en) | 1996-12-24 | 2003-10-09 | Biogen, Inc. | Stable liquid interferon formulations |
| CN101506232A (zh) * | 2006-08-08 | 2009-08-12 | 诺瓦提斯公司 | 具有增强的生物活性的重组干扰素-β |
| US8114630B2 (en) | 2007-05-02 | 2012-02-14 | Ambrx, Inc. | Modified interferon beta polypeptides and their uses |
| EP2207890A4 (en) * | 2007-10-05 | 2010-12-15 | Barofold Inc | HIGH PRESSURE PROCESSING OF AGGREGATED INTERFERONS |
| CN106132983B (zh) * | 2014-04-04 | 2021-03-26 | 阿雷斯贸易股份有限公司 | 新型IFN-β蛋白类似物 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2216345C1 (ru) * | 2002-03-21 | 2003-11-20 | Закрытое Акционерное Общество "Биокад" | Средство, обладающее иммуномодулирующим, противовирусным, противобактериальным, регенерирующим, репаративным, мембрано- и гепатопротекторным действием |
| WO2004087753A1 (en) * | 2003-03-31 | 2004-10-14 | Samsung Fine Chemicals Co., Ltd. | Mutein of human interferon-beta and its preparation method |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4588585A (en) | 1982-10-19 | 1986-05-13 | Cetus Corporation | Human recombinant cysteine depleted interferon-β muteins |
| US4737462A (en) | 1982-10-19 | 1988-04-12 | Cetus Corporation | Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β |
| US4959314A (en) | 1984-11-09 | 1990-09-25 | Cetus Corporation | Cysteine-depleted muteins of biologically active proteins |
| GB9111902D0 (en) | 1991-06-03 | 1991-07-24 | Glaxo Group Ltd | Chemical compounds |
| TR199901968T2 (xx) | 1996-12-24 | 1999-12-21 | Biogen, Inc. | Sabit s�v� interferon form�lleri. |
| US20030190307A1 (en) | 1996-12-24 | 2003-10-09 | Biogen, Inc. | Stable liquid interferon formulations |
| US6696423B1 (en) | 1997-08-29 | 2004-02-24 | Biogen, Inc. | Methods and compositions for therapies using genes encoding secreted proteins such as interferon-beta |
| EP1426058A3 (de) * | 1997-09-23 | 2004-07-28 | Dr. Rentschler Biotechnologie GmbH | Flüssige Interferon-Beta Formulierungen |
| ATE488529T1 (de) | 1999-07-28 | 2010-12-15 | Genentech Inc | Zusammensetzungen und verfahren zur behandlung von tumoren |
| ES2180416B1 (es) | 2001-03-12 | 2004-06-01 | BIOTOOLS BIOTECHNOLOGICAL & MEDICAL LABORATORIES, S.A. | Procedimiento para la preparacion de mezclas de reaccion estabilizadas, total o parcialmente desecadas, que comprenden, al menos, una enzima, mezclas de reaccion y kits que las contienen. |
| AR034749A1 (es) * | 2001-07-09 | 2004-03-17 | Schering Ag | Formulaciones de interferon beta humano |
-
2005
- 2005-11-10 ES ES05818235T patent/ES2318575T3/es not_active Expired - Lifetime
- 2005-11-10 AT AT05818235T patent/ATE415421T1/de active
- 2005-11-10 PL PL05818235T patent/PL1809662T3/pl unknown
- 2005-11-10 MX MX2007004990A patent/MX2007004990A/es active IP Right Grant
- 2005-11-10 KR KR1020077011869A patent/KR101330626B1/ko not_active Expired - Fee Related
- 2005-11-10 JP JP2007540208A patent/JP4891250B2/ja not_active Expired - Fee Related
- 2005-11-10 RU RU2007121515/04A patent/RU2404190C2/ru not_active IP Right Cessation
- 2005-11-10 BR BRPI0517697-2A patent/BRPI0517697A/pt not_active IP Right Cessation
- 2005-11-10 AU AU2005304486A patent/AU2005304486B2/en not_active Ceased
- 2005-11-10 DE DE602005011321T patent/DE602005011321D1/de not_active Expired - Lifetime
- 2005-11-10 CN CN2005800381182A patent/CN101056890B/zh not_active Expired - Fee Related
- 2005-11-10 WO PCT/US2005/040758 patent/WO2006053134A2/en not_active Ceased
- 2005-11-10 EP EP05818235A patent/EP1809662B1/en not_active Expired - Lifetime
- 2005-11-10 PT PT05818235T patent/PT1809662E/pt unknown
- 2005-11-10 US US11/271,516 patent/US7595040B2/en not_active Expired - Fee Related
- 2005-11-10 CA CA2587061A patent/CA2587061C/en not_active Expired - Fee Related
-
2009
- 2009-03-25 US US12/410,540 patent/US20090263355A1/en not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2216345C1 (ru) * | 2002-03-21 | 2003-11-20 | Закрытое Акционерное Общество "Биокад" | Средство, обладающее иммуномодулирующим, противовирусным, противобактериальным, регенерирующим, репаративным, мембрано- и гепатопротекторным действием |
| WO2004087753A1 (en) * | 2003-03-31 | 2004-10-14 | Samsung Fine Chemicals Co., Ltd. | Mutein of human interferon-beta and its preparation method |
Non-Patent Citations (1)
| Title |
|---|
| KAWASAKI HIROAKI ET AL: "A protein with antimicrobial activity in the skin of Schlegel's green tree frog Rhacophorus schlegelii (Rhacophoridae) identified as histone H2B." BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2003, vol. 312, no.4, pages 1082-1086. * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2739261C1 (ru) * | 2019-12-31 | 2020-12-22 | Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) | Способ количественного определения антипролиферативной активности интерферона-бета человека |
| RU2812047C1 (ru) * | 2020-04-29 | 2024-01-22 | Абион Инк. | Вариант интерферона-бета человека с двойной мутацией и способ улучшения стабильности варианта интерферона-бета человека |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101056890A (zh) | 2007-10-17 |
| CN101056890B (zh) | 2012-05-09 |
| US20060120998A1 (en) | 2006-06-08 |
| KR101330626B1 (ko) | 2013-11-18 |
| WO2006053134A2 (en) | 2006-05-18 |
| CA2587061C (en) | 2011-08-16 |
| RU2007121515A (ru) | 2008-12-20 |
| ATE415421T1 (de) | 2008-12-15 |
| JP2008519769A (ja) | 2008-06-12 |
| KR20070084559A (ko) | 2007-08-24 |
| AU2005304486B2 (en) | 2011-08-11 |
| EP1809662A2 (en) | 2007-07-25 |
| BRPI0517697A (pt) | 2008-10-14 |
| PL1809662T3 (pl) | 2009-07-31 |
| MX2007004990A (es) | 2007-06-14 |
| JP4891250B2 (ja) | 2012-03-07 |
| US20090263355A1 (en) | 2009-10-22 |
| DE602005011321D1 (de) | 2009-01-08 |
| AU2005304486A1 (en) | 2006-05-18 |
| EP1809662B1 (en) | 2008-11-26 |
| US7595040B2 (en) | 2009-09-29 |
| PT1809662E (pt) | 2009-02-26 |
| CA2587061A1 (en) | 2006-05-18 |
| ES2318575T3 (es) | 2009-05-01 |
| WO2006053134A3 (en) | 2006-08-31 |
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| MM4A | The patent is invalid due to non-payment of fees |
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