RU2402314C1 - Feet care product - Google Patents

Abstract

FIELD: medicine.

SUBSTANCE: invention refers to cosmetology, particularly to a feet care product. The feet care product contains an oil phase, an inorganic excipient, hexamethylene tetramine, a cosmetically acceptable solid base and essences taken in a certain ratio.

EFFECT: product is effective for feet care, exhibits improved hidroschesis.

6 cl, 3 tbl

Description

The invention relates to cosmetology, in particular to cosmetics for the care of the skin of the feet of a person and can be used as a therapeutic and prophylactic and deodorizing agent.

Known foot cream "Effect" containing oil from fruit seeds and almonds, distilled glycerin, cosmetic stearin, pure triethanolamine, distilled monoglycerides, glycerol monostearate, coniferous sodium chlorophyllin, vitamin F, urea, paraform, purified ethyl alcohol, rectified ethyl distilled , perfume and water [Wojciechowska A.L. and other Cosmetics today, - M .: Chemistry, 1988, S. 39-41].

The well-known cream does not meet the modern requirements of consumers for foot care products, because does not have a pronounced antiseptic, antifungal effect, can cause allergic reactions due to the presence of ethyl alcohol in its composition.

In connection with the changed attitude of consumers to foot care products, consumer expectations are aimed at a pronounced complex effect provided by foot care products. In Russia, a wide range of modern foot care products is known with therapeutic, therapeutic and prophylactic, massage effects, with nourishing, moisturizing, exfoliating, deodorizing and other effects in the form of cream, gel, balm, lotion. For example, the Tentorium company Ali Comfort foot cream is known for massage based on beekeeping products, as well as phytoextracts, soybean and coconut oils, emulsion wax, ethyl alcohol, which has an antifungal effect. Oriflame foot creams of exfoliating and polishing action are also known, which along with a cosmetically acceptable base contain particles of crushed almonds and a dietary supplement in the form of eucalyptus oil; cream “Veri-Gon” of therapeutic and preventive action to increase skin tone with horse chestnut extract; Balm "Comfort" of the company "Riza honey" with a deodorizing effect based on kaolin; Sofya, a therapeutic foot cream that enhances blood circulation, containing leech extracts, extracts of medicinal plants, oils and vitamins; Vivasan nourishing cream containing vitamin E and chamomile extract as biologically active substances; Thalaspa moisturizer containing essential oils, shea butter, lemon, orange, grape seed oil, chamomile extract.

Known funds, possessing many useful properties, do not have a pronounced effect against sweating of the feet and do not provide a lasting effect to eliminate the smell of sweat.

Known foot cream containing emulsifiers, oil phase, moisturizing and softening components, structure-forming component, dietary supplements, ethyl alcohol, preservatives, perfume and water in certain proportions [RF Patent No. 2139704, IPC A61K 7/00, A61K / 7 / 48, 1999].

The well-known cream promotes the healing of small cracks, has a beneficial effect on microcirculation, relieves leg fatigue, but its effect on sweating feet and eliminating sweat odor is weak. In addition, the known product as biologically active additives that impart a deodorizing effect, contains water-alcohol extracts of biologically active plants, as well as ethyl alcohol, which can cause dry skin.

Also known is a tool for treating the skin of the feet in the form of a deodorant lotion, which contains, wt.%, Urotropin 1,0-10; borax 0.5-5.0; aspirin 0.1-1.0; succinic acid 0.1-1.0; citric acid 0.1-1.0; ethyl alcohol - the rest. The deodorant additionally contains glycerin in an amount of 2.5-5.0 wt.%. [RF patent No. 2288696, IPC A61K 8/49; A61K 8/19; A61K 8/36; A61K 8/34; A61Q 15/00, (2006.01), 2006].

The use of a well-known deodorant every 12 hours reduces the smell of sweat below the threshold of human smell. Reducing the smell of sweat is associated with a bactericidal and antiseptic effect due to the presence of aspirin in ethanol and at the same time the presence of borax and succinic and citric acids. However, the known agent does not provide a lasting effect, and the use of ethyl alcohol can cause dry skin, irritating and allergenic effect with frequent use.

Known means for feet containing, wt.%: Perfume oil or butyl stearate, or isopropyl palmitate, or isopropyl myristate 3.0-5.0; vegetable oil 5.0-7.0; deodorized mink fat, or mink oil, or chicken fat, or chicken oil 3.0–5.0; cosmetic stearin 0.5-2.0; triethanolamine 0.5-1.0; emulsion wax 3.0-5.0; distilled monoglycerides (MHD), or glycerol monostearate, or DEG stearate 3.0-5-5; anhydrous lanolin or hydroxyethylated lanolin - not more than 1.0; ethyl alcohol 3.0-5.0; carbamide 0.5-1.0; camphor 0.15-1.0; boric acid or salicylic acid 0.2-0.5; high molecular weight chitosan 0.5-1.0; collagenase 0.1-0.5; phenoxyethanol 0.5-1.0; preservative 0.05; perfume 0.2-1.0; drinking water - up to 100. The foot product may additionally contain urotropin in an amount of not more than 0.5 wt.% [RF Patent No. 2112500, IPC A61K 7/00, 1998].

The known agent has a soft consistency, is quickly absorbed, has a pronounced epithelizing and keratolytic effect on a rough, cracked surface, promotes rapid healing of cracks, does not have an irritating and allergenic effect. However, the known composition does not have a pronounced long-term bactericidal effect and, at the same time, action against sweating.

Closest to the proposed is a deodorizing composition containing urotropin (hexamethylenetetramine) 14-20%, zinc dioxide (inorganic filler) 16-23%, starch (organic filler) 16-23%, petrolatum (oil phase) 38-43% and perfume 0.5-1.2% (IL patent No. 49107, 1979).

The known product does not contain an alcohol base and has a prolonged deodorizing effect up to 7-15 days, however, it does not exhibit a simultaneous action aimed at suppressing sweating of the skin of the feet.

An object of the invention is to expand the range of foot care products that do not contain an alcohol base and have a comprehensive therapeutic and prophylactic effect with a prolonged combined bactericidal effect and an action aimed at suppressing sweating.

The problem is solved in that the skin care product for the feet contains a cosmetically acceptable solid base, oil phase, inorganic filler, hexamethylenetetramine and essential oils in the following ratio, wt.%:

Solid base 0.01-30.0 Inorganic filler 10.0-25.0 Essential oils 0.05-0.5 Hexamethylenetetramine 10.0-20.0 Oil phase Rest

The inventive composition may contain cosmetically acceptable perfume in an amount of up to 2.0 wt.%.

As a cosmetically acceptable solid base, the proposed composition contains ceresin and / or paraffins, solid petroleum and / or microcrystalline wax and / or beeswax and / or carnauba wax and / or ozokerite and other similar components or mixtures thereof. As a solid base, domestic or imported raw materials produced on an industrial scale can be used, for example, solid petroleum paraffins in accordance with GOST 23683-89, oil ceresins in accordance with TU 38 401218-94 (instead of TU 38 1011235-89), Ozokerite 7366, Micromax 6089, Carnauba wax T1 yellow filtered in cereal (Brazil), 8105 Beeswax yellow and other similar substances.

As an inorganic filler, the proposed composition contains talc and / or kaolin and / or sillitin and / or titanium dioxide pigment and / or silica and / or zinc dioxide and other similar components or mixtures thereof. As an inorganic filler, domestic or imported raw materials produced on an industrial scale can be used, for example, talc, fine powder of high purity, corresponding to the pharmacopoeia of Europe, Great Britain, USA, E553b; zinc oxide according to GOST 10262-73; enriched kaolin for the cosmetic industry according to TU 5729-016-48174985-2003; Silika, a highly dispersed silica powder; Sillitin z 89, which is a mixture of fine powders of quartz and kaolinite; Aerosil 300, which is hydrogenated pyrogenic silicon dioxide with a specific surface area of 300 m ² / g, Kronos 1171, which is titanium dioxide, and other similar substances.

As a target bactericidal additives, the proposed composition contains hexamethylenetetramine (HMT), also known as urotropin. As HMT, hexamethylenetetramine (urotropin) (CH ₂ ) ₆ N ₄ food, which meets the European pharmaceutical standards DAB, Ph Eur, BR, USP, can be used.

As an essential oil, the composition contains coriander oil and / or lavender oil and / or eucalyptus oil and / or peppermint oil and / or tea tree oil and other similar components or mixtures thereof. As an essential oil, domestic or imported raw materials produced on an industrial scale can be used, for example, eucalyptus oil of the Eucalyptus Oil brand 100180 / DUB 10, peppermint oil of the Minzol brand, lavender oil of the Lavender brand 110442, coriander oil of the Koriandrol Fraktion 1 brand 402931, tea tree oil Brands Tea Tree Oil 744-125 and other similar substances.

As a liquid base, the composition contains an oil phase, preferably perfume oil. Dimethicone or petroleum jelly or other similar components may also be used as the oil phase. As the oil phase can be used domestic or imported raw materials produced on an industrial scale under the brand name Vaseline cosmetic according to TU 9158-038-00333859-2000 manufactured by Concern KALINA OJSC, PROL White Mineral Oil; Dow Corning 200 (R) Fluid, 350CST, Dylan 45035 / E.

As a flavoring agent, any flavoring agent known for these purposes can be used, for example, Dylan 45/035 E base composition.

Comparison of the proposed composition with the known one reveals the following distinctive features: the composition of the composition containing hexamethylenetetramine (HMT) as a target bactericidal additive in combination with an inorganic filler, as well as essential oils, while the composition is characterized by a certain quantitative ratio of ingredients. The above allows us to conclude that the claimed composition of the foot cream meets the criterion of "novelty."

The use of inorganic fillers, a solid base, perfume and essential oils in creams is known. It is also known the use of hexamethylenetetramine (HMT) with the achievement of bactericidal and anti-inflammatory activity (see, for example, M.D. Mashkovsky. Medicines. Handbook, M., 1973). HMT in the above known formulations is used in amounts not exceeding 10 wt.%, Due to its irritating effect in contact with skin. In the inventive composition, HMT is used in an amount of 10-20 wt.% In combination with an inorganic filler in the environment of perfume oil and a structure-forming component (solid base), which allows to obtain an unexpected result - the simultaneous achievement of a previously known bactericidal action, as well as an action aimed at suppressing sweating. The effect of suppressing perspiration in the compositions of skin creams, associated with the introduction of HMT in high amounts, was not previously known in science and technology. Moreover, the claimed composition allows to provide a long-term result even with a single application. The effect can be explained by the ratio of HMT and inorganic filler, which ensures their physical interaction with each other due to adsorption forces, as a result of which when applying the cream to the skin, HMT, without direct contact with the skin, provides the above effect, excluding the possibility of an irritating effect. The use of HMT in conjunction with an inorganic filler in an oil phase medium and a cosmetically acceptable base, which acts as a structurant, allows us to solve the problem, achieving both a bactericidal effect and a sweating suppression effect, while the effect remains for up to 48 hours even with a single application. The introduction of essential oils can enhance the bactericidal effect and improve the tonic and nutritional properties of the claimed composition. Since the claimed composition is characterized by a new qualitative composition, a new quantitative ratio of ingredients and provides a previously unknown effect of suppressing perspiration with a certain content of HMT in an oil composition containing an inorganic filler, we can conclude that it meets the criterion of "inventive step".

To obtain the claimed composition, cosmetic raw materials are used according to regulatory documents from foreign and Russian manufacturers of cosmetic raw materials, the compositions are prepared using well-known equipment using known technologies. The above allows us to conclude that the claimed composition meets the criterion of "industrial applicability".

The composition of the cream for skin care of the legs is obtained as follows.

The estimated amounts of the oil phase (for example, perfume oil) and the solid base (for example, a mixture of ozokerite and paraffin) are loaded into the cooking apparatus and the resulting mixture is heated with stirring to a temperature of 85-90 ° C until all components are completely melted. The resulting system is cooled to 60-65 ° C. Then, the estimated amount of essential oils and perfumes are loaded into the apparatus with stirring. Cooling is continued until the system reaches a temperature of 35-40 ° C. Next, the previously prepared dry mixture of components consisting of hexamethylenetetramine and inorganic fillers is loaded into the apparatus with constant stirring. After homogenization of the above composition, the final cooling of the cream is carried out. The finished cream is pumped into the filling hopper, from where it enters the packaging machines.

The compositions of the obtained foot creams are shown in table 1 (see the end of the description).

Table 1 shows examples 1-6 according to the invention. Tests of the claimed compositions were carried out on a group of volunteers of 30 people aged 21 to 47 years (10 women, 20 men with increased sweating feet and bromhidrosis of varying severity) in the test laboratory center of the Research Institute of Occupational Medicine RAMS, evaluating the effect on the skin of the feet (dermatological control), the duration of the effect of eliminating bromhidrosis, the degree of reduction (%) of increased sweating, the reaction of the skin within 4 weeks.

Clinical examination was performed according to well-known methods.

A quantitative determination of automicro flora was carried out by the method of flushing in accordance with the approved methodological guidelines “Testing methods of disinfectants to assess their safety and effectiveness”, Ministry of Health of the Russian Federation, Moscow, 1998. Flushing from the feet of volunteers was selected: initial flush (without the use of the claimed composition) and after 12 hours after applying the inventive composition. Repeated swabs were taken on days 3 and 4. After selection of the washout, they were plated on a solid nutrient medium, incubated in a thermostat for 48 hours, and the grown colonies were counted.

The level of transepidermal water loss (TEPV) depends on the activity of sweat glands. Sweating (TEPV) was determined instrumentally using the Tevametry method according to the rate of liquid evaporation from the skin surface at a temperature of 20 ° C and an air humidity of 40-60% using a Tewameter TM 300-MPA 580 instrument (Germany).

As the studies showed, during a visual examination of the skin of the feet after application of the claimed composition, no pathological reactions were observed (hyperemia, swelling, rash, peeling, itching). When examining and interviewing volunteers after a single application of the inventive composition, the majority of subjects had a positive result in the form of reducing excessive sweating and eliminating / reducing unpleasant odors. The data on the dynamics of unpleasant odor and sweating of the skin of the feet are presented in table 2.

table 2 Symptom Before using the claimed composition After using the claimed composition Bad smell 2.67 ± 0.61 0.47 ± 0.73 (↓ 82.4%) Sweating skin 2.63 ± 0.49 1.56 ± 0.63 (↓ 40.7%)

As can be seen from the data presented in table 2, the severity of the unpleasant odor of the skin of the feet of the subjects decreased after the first application of the inventive composition by an average of 82.4% compared with the initial value. The high efficiency of the claimed composition in relation to bromohydrosis was also noted - in 63.3% of cases the symptom disappeared after the first application. In 30% of cases, the smell persisted, but a marked decrease in its intensity was noted. The duration of the effect of the complete elimination of bromohydrosis (deodorizing effect) ranged from 3 to 7 days and averaged 5-6 days.

Increased sweating of the skin of the feet also significantly decreased compared to the initial indicator: after the first application in 76.7% of cases, a positive effect was noted in the form of its fall by an average of 40.7%.

The results of the study of the level of TEPV in dynamics are shown in table 3.

Table 3 The control TEPV level, g / h / m ² Before using the claimed composition 69.8 ± 0.24 After using the claimed composition (after 12 hours) 36.2 ± 0.35 After using the claimed composition (after 24 hours) 38.8 ± 0.01 After using the claimed composition (after 48 hours) 40.1 ± 0.86

As can be seen from the data shown in table 3, the effective effect of the claimed composition on the increased activity of the sweat glands is already evident within the first 48 hours (decrease in activity by an average of 42.5%).

During the study, tolerance was good in all subjects, no side effects were detected. The inventive composition does not cause allergies and skin irritations and does not cause negative subjective sensations, has a pleasant creamy consistency, is easy to apply, well distributed, quickly absorbed. Active physical activity, washing with soap does not weaken the effectiveness of the claimed composition. The deodorizing effect on a 5-point scale was rated by all subjects as “5”. The inventive composition has significant antimicrobial activity against the automicroflora of the skin of the feet and effectively inhibits the growth of microorganisms for a long time after a single application.

The inventive composition can be successfully used both in cosmetology and dermatologists for hygienic skin care of the feet, prone to excessive sweating and bromohydrosis.

Table 1 The compositions of the skin care feet COMPONENTS EXAMPLES OF THE INVENTION one 2 3 four 5 6 Solid base, in particular: solid paraffins 5,0 - 0.01 25.0 10.0 5,0 - ceresin - 10.0 - - - - - microcrystalline wax - - - - 10.0 - - beeswax - 2.5 - - - - - carnauba wax - 2.5 - - - - - ozokerite 10.0 - - 5,0 - 5,0 Hexamethylenetetramine (HMT) 10.0 20,0 10.0 10.0 15.0 15.0 Inorganic filler in particulars: - talc 10.0 - 20,0 10.0 10.0 5,0 - kaolin - 5,0 - - 5,0 - - sillitin - - - - - 5,0 - silica - - - - - 5,0 - titanium dioxide pigment 2.5 - 5,0 - - - - zinc dioxide - 5,0 - - - - Essential oil, in particular: - coriander oil 0.05 - 0.25 0.05 0.05 0.05 - lavender oil 0.05 - 0.25 - - 0.05 - eucalyptus oil - 0,025 - 0.05 - - - peppermint oil - 0,025 - 0.05 - - - tea tree oil - - - - 0.05 - Oil phase in particular - perfume oil 62,4 40,0 34.49 49.85 47.9 58.9 dimethicone - 14.95 - - - - - petroleum jelly - - 30,0 - - - Perfume - - - - 2.0 1,0

Claims (6)

1. The skin care product for the feet contains an oil phase, an inorganic filler, hexamethylenetetramine, characterized in that it further comprises a cosmetically acceptable solid base and essential oils in the following ratio, wt.%:
Cosmetically acceptable solid base 0.01-30.0 Inorganic filler 10.0-25.0 Essential oils 0.05-0.5 Hexamethylenetetramine 10.0-20.0 Oil phase Rest 2. The means for skin care of the legs according to claim 1, characterized in that as a cosmetically acceptable solid base contains ceresin and / or solid petroleum paraffins, and / or microcrystalline wax, and / or beeswax, and / or carnauba wax , and / or ozokerite. 3. The means for skin care of the legs according to claim 1, characterized in that the oil phase contains perfume oil and / or dimethicone and / or petroleum jelly. 4. The means for skin care of the legs according to claim 1, characterized in that the inorganic filler contains talc and / or kaolin and / or sillitin and / or titanium dioxide pigment and / or silica and / or dioxide zinc. 5. The foot care product according to claim 1, characterized in that the essential oil contains coriander oil and / or lavender oil and / or eucalyptus oil and / or peppermint oil and / or tea tree oil. 6. The tool for skin care of the legs according to claim 1, characterized in that it further comprises a cosmetically acceptable perfume in an amount of up to 2.0 wt.%.