RU2337108C2 - Полипептиды для индукции защитного иммунного ответа против staphylococcus aureus - Google Patents
Полипептиды для индукции защитного иммунного ответа против staphylococcus aureus Download PDFInfo
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2639287C2 (ru) * | 2012-06-27 | 2017-12-20 | Ф. Хоффманн-Ля Рош Аг | Способ отбора и получения высокоселективных и мультиспецифичных нацеливающих групп с заданными свойствами, включающих по меньшей мере две различные связывающие группировки, и их применения |
| US11421022B2 (en) | 2012-06-27 | 2022-08-23 | Hoffmann-La Roche Inc. | Method for making antibody Fc-region conjugates comprising at least one binding entity that specifically binds to a target and uses thereof |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT410798B (de) | 2001-01-26 | 2003-07-25 | Cistem Biotechnologies Gmbh | Verfahren zur identifizierung, isolierung und herstellung von antigenen gegen ein spezifisches pathogen |
| JP2007528217A (ja) * | 2004-02-18 | 2007-10-11 | メルク エンド カムパニー インコーポレーテッド | スタヒロコッカス・アウレウスに対する防御免疫応答を誘導するためのポリペプチド |
| AU2005310981A1 (en) * | 2004-10-25 | 2006-06-08 | The University Of Western Ontario | Vaccines, compositions and methods based on Staphylococcus aureus iron-regulated surface determinants IsdA, IsdB, and IsdC |
| GB0526038D0 (en) * | 2005-12-21 | 2006-02-01 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| WO2007089470A2 (en) * | 2006-01-27 | 2007-08-09 | Merck & Co., Inc. | Antigen-binding proteins targeting s. aureus orf0657n |
| US8124108B2 (en) | 2007-01-24 | 2012-02-28 | Merck Sharp & Dohme Corp. | Polypeptides for inducing a protective immune response against Staphylococcus epidermidis |
| EP2374466B1 (en) * | 2007-05-04 | 2013-08-28 | Krönke, Martin | Protective staphylococcus aureus vaccine based on cell wall-associated proteins |
| BRPI0811193A2 (pt) * | 2007-05-31 | 2014-11-11 | Merck & Co Inc | Proteína de ligação a antígeno isolada, ácido nucleico, célula recombinante, métodos para produzir uma proteína e para proteger ou tratar contra uma infecção por s. aureus em paciente, composição farmacêutica, uso da proteína de ligação a antígeno, e, polipeptídeo. |
| US8071561B2 (en) | 2007-08-16 | 2011-12-06 | Chrontech Pharma Ab | Immunogen platform |
| US9181329B2 (en) | 2007-08-31 | 2015-11-10 | The University Of Chicago | Methods and compositions related to immunizing against Staphylococcal lung diseases and conditions |
| KR101661946B1 (ko) | 2007-08-31 | 2016-10-05 | 유니버시티 오브 시카고 | 스타필로코커스 폐 질환 및 상태에 대한 면역화와 관련된 방법 및 조성물 |
| US8758765B2 (en) | 2008-07-29 | 2014-06-24 | The University Of Chicago | Compositions and methods related to Staphylococcal bacterium proteins |
| JP2012509665A (ja) | 2008-11-26 | 2012-04-26 | メルク・シャープ・エンド・ドーム・コーポレイション | スタフィロコッカス・アウレウス（ｓｔａｐｈｙｌｏｃｏｃｃｕｓａｕｒｅｕｓ）に対する防御免疫応答を誘導するポリペプチド |
| SMT202000246T1 (it) | 2009-04-03 | 2020-07-08 | Univ Chicago | Composizioni e metodi relativi a varianti della proteina a (spa) |
| AU2010238255B2 (en) | 2009-04-14 | 2014-10-16 | Novartis Ag | Compositions for immunising against Staphylococcus aureus |
| GB0913680D0 (en) | 2009-08-05 | 2009-09-16 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| GB0913681D0 (en) | 2009-08-05 | 2009-09-16 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| MX338753B (es) | 2009-09-30 | 2016-04-29 | Novartis Ag | Conjugacion de polisacaridos capsulares de tipo 5 y de tipo 8 de staphylococcus aureus. |
| CN109134677A (zh) | 2009-10-30 | 2019-01-04 | 诺华股份有限公司 | 金黄色葡萄球菌5型和8型荚膜多糖的纯化 |
| GB0919690D0 (en) | 2009-11-10 | 2009-12-23 | Guy S And St Thomas S Nhs Foun | compositions for immunising against staphylococcus aureus |
| WO2011113056A1 (en) * | 2010-03-12 | 2011-09-15 | The Trustees Of The University Of Pennsylvania | Methods for preventing and treating staphylococcus aureus colonization, infection, and disease |
| US8821894B2 (en) | 2010-07-02 | 2014-09-02 | The University Of Chicago | Compositions and methods related to protein A (SpA) variants |
| EP2593133A4 (en) | 2010-07-13 | 2014-11-26 | Merck Sharp & Dohme | STAPHYLOCOCCUS AUREUS SURFACE PROTEIN SA1789 AND PROTECTIVE VACCINE BASED ON IT |
| EP2638058B1 (en) | 2010-11-12 | 2017-01-11 | Merck Sharp & Dohme Corp. | Enolase peptide conjugate vaccines against staphylococcus aureus |
| US8945588B2 (en) | 2011-05-06 | 2015-02-03 | The University Of Chicago | Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides |
| MX2014002363A (es) | 2011-09-01 | 2014-04-14 | Novartis Ag | Formulaciones de antigenos de staphylococcus aureus con adyuvante. |
| US9527892B2 (en) | 2011-10-31 | 2016-12-27 | Merck Sharp & Dohme Corp. | Protective vaccine based on Staphylococcus aureus SA2451 protein |
| WO2014011645A1 (en) | 2012-07-10 | 2014-01-16 | Merck Sharp & Dohme Corp. | Protective vaccine based on staphylococcus aureus sa2493 protein |
| US10738338B2 (en) | 2016-10-18 | 2020-08-11 | The Research Foundation for the State University | Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate |
| BR112021022902A2 (pt) | 2019-05-14 | 2022-01-25 | Univ Chicago | Métodos e composições que compreendem variantes de proteína a staphylococcus (spa) |
| US12528882B2 (en) | 2019-09-13 | 2026-01-20 | The University Of Chicago | Methods and compositions for treating staphylococcal infections |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000071585A1 (en) * | 1999-05-03 | 2000-11-30 | Medarex, Inc. | Human antibodies to staphylococcus aureus |
| WO2003053462A3 (en) * | 2001-12-11 | 2003-09-04 | Merck & Co Inc | Staphylococcus aureus exopolysaccharide and process |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US6248329B1 (en) * | 1998-06-01 | 2001-06-19 | Ramaswamy Chandrashekar | Parasitic helminth cuticlin nucleic acid molecules and uses thereof |
| GB0014907D0 (en) * | 2000-06-20 | 2000-08-09 | Univ Sheffield | Antigenic polypeptides |
| AT410798B (de) * | 2001-01-26 | 2003-07-25 | Cistem Biotechnologies Gmbh | Verfahren zur identifizierung, isolierung und herstellung von antigenen gegen ein spezifisches pathogen |
| WO2002102829A2 (en) * | 2001-06-15 | 2002-12-27 | Inhibitex, Inc. | Cross-reactive monoclonal and polyclonal antibodies which recognize surface proteins from coagulase-negative staphylococci and staphylococcus aureus |
| WO2003042249A2 (en) * | 2001-11-12 | 2003-05-22 | Novo Nordisk A/S | Peptide purification by means of metal ion affinity chromatography |
| US20080050361A1 (en) * | 2004-10-25 | 2008-02-28 | Heinrichs David E | Staphylococcus aureas specific anti-infectives |
| CA2637598A1 (en) * | 2006-01-18 | 2007-02-14 | University Of Chicago | Compositions and methods related to staphylococcal bacterium proteins |
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- 2004-07-22 CA CA002532370A patent/CA2532370A1/en not_active Abandoned
- 2004-07-22 EP EP04778847A patent/EP1651166B8/en not_active Expired - Lifetime
- 2004-07-22 ES ES04778847T patent/ES2342778T3/es not_active Expired - Lifetime
- 2004-07-22 PT PT04778847T patent/PT1651166E/pt unknown
- 2004-07-22 BR BRPI0412799-4A patent/BRPI0412799A/pt not_active Application Discontinuation
- 2004-07-22 NZ NZ544542A patent/NZ544542A/en not_active IP Right Cessation
- 2004-07-22 HR HR20100240T patent/HRP20100240T1/hr unknown
- 2004-07-22 JP JP2006521226A patent/JP2007502101A/ja active Pending
- 2004-07-22 DK DK04778847.6T patent/DK1651166T3/da active
- 2004-07-22 SI SI200431389T patent/SI1651166T1/sl unknown
- 2004-07-22 AT AT04778847T patent/ATE457737T1/de active
- 2004-07-22 DE DE602004025579T patent/DE602004025579D1/de not_active Expired - Lifetime
- 2004-07-22 NZ NZ570750A patent/NZ570750A/en not_active IP Right Cessation
- 2004-07-22 PL PL04778847T patent/PL1651166T3/pl unknown
- 2004-07-22 WO PCT/US2004/023523 patent/WO2005009379A2/en not_active Ceased
- 2004-07-22 MX MXPA06000854A patent/MXPA06000854A/es active IP Right Grant
- 2004-07-22 RU RU2006105498/13A patent/RU2337108C2/ru not_active IP Right Cessation
-
2005
- 2005-12-30 IS IS8213A patent/IS8213A/is unknown
-
2006
- 2006-01-19 IL IL173253A patent/IL173253A0/en unknown
- 2006-02-23 NO NO20060898A patent/NO20060898L/no not_active Application Discontinuation
-
2010
- 2010-04-30 US US12/771,345 patent/US20100247561A1/en not_active Abandoned
- 2010-05-14 CY CY20101100419T patent/CY1110028T1/el unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000071585A1 (en) * | 1999-05-03 | 2000-11-30 | Medarex, Inc. | Human antibodies to staphylococcus aureus |
| WO2003053462A3 (en) * | 2001-12-11 | 2003-09-04 | Merck & Co Inc | Staphylococcus aureus exopolysaccharide and process |
Non-Patent Citations (1)
| Title |
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| РОЙТ А. и др. Иммунология, М., Изд. Мир, 2000 г., стр.237-238. * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2639287C2 (ru) * | 2012-06-27 | 2017-12-20 | Ф. Хоффманн-Ля Рош Аг | Способ отбора и получения высокоселективных и мультиспецифичных нацеливающих групп с заданными свойствами, включающих по меньшей мере две различные связывающие группировки, и их применения |
| US10106612B2 (en) | 2012-06-27 | 2018-10-23 | Hoffmann-La Roche Inc. | Method for selection and production of tailor-made highly selective and multi-specific targeting entities containing at least two different binding entities and uses thereof |
| US11407836B2 (en) | 2012-06-27 | 2022-08-09 | Hoffmann-La Roche Inc. | Method for selection and production of tailor-made highly selective and multi-specific targeting entities containing at least two different binding entities and uses thereof |
| US11421022B2 (en) | 2012-06-27 | 2022-08-23 | Hoffmann-La Roche Inc. | Method for making antibody Fc-region conjugates comprising at least one binding entity that specifically binds to a target and uses thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| US20100247561A1 (en) | 2010-09-30 |
| ES2342778T3 (es) | 2010-07-14 |
| EP1651166A2 (en) | 2006-05-03 |
| JP2007502101A (ja) | 2007-02-08 |
| DK1651166T3 (da) | 2010-05-31 |
| DE602004025579D1 (de) | 2010-04-01 |
| ATE457737T1 (de) | 2010-03-15 |
| MXPA06000854A (es) | 2006-03-30 |
| IS8213A (is) | 2005-12-30 |
| EP1651166A4 (en) | 2008-03-05 |
| NZ570750A (en) | 2009-12-24 |
| NO20060898L (no) | 2006-04-24 |
| EP1651166B8 (en) | 2010-05-19 |
| CA2532370A1 (en) | 2005-02-03 |
| NZ544542A (en) | 2009-01-31 |
| IL173253A0 (en) | 2006-06-11 |
| RU2006105498A (ru) | 2006-09-10 |
| AU2004258979B2 (en) | 2007-12-06 |
| WO2005009379A2 (en) | 2005-02-03 |
| BRPI0412799A (pt) | 2006-09-26 |
| PT1651166E (pt) | 2010-04-23 |
| KR20060065643A (ko) | 2006-06-14 |
| WO2005009379A3 (en) | 2006-11-30 |
| AU2004258979A1 (en) | 2005-02-03 |
| PL1651166T3 (pl) | 2010-08-31 |
| CY1110028T1 (el) | 2015-01-14 |
| EP1651166B1 (en) | 2010-02-17 |
| US20060177462A1 (en) | 2006-08-10 |
| SI1651166T1 (sl) | 2010-06-30 |
| HRP20100240T1 (hr) | 2010-09-30 |
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| Date | Code | Title | Description |
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| PD4A | Correction of name of patent owner | ||
| MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20120723 |