RU2289440C2 - Method for treating the cases of bronchial asthma - Google Patents

Abstract

FIELD: medicine.

SUBSTANCE: method involves applying electrophoresis directly in esophagus at the level of trachea bifurcation. Probe having silver electrode is introduced into esophagus. The probe is connected to positive pole of electrophoresis apparatus and reservoir containing solution. The second electrode connected to the negative pole, is placed onto anterior abdominal wall at esophagus projection level. Drug solution is used for applying electrophoresis. It contains silver, copper and zinc, each taken in the amount of 0.5 mg/l. Electrophoresis is carried out with current of 1.5 mA. Solution supply rate is 30-40 drops per 1 min during 30-40 min. The total treatment course is 10 procedures long.

EFFECT: increased drug adsorption on virus and bacterium cell membranes.

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Description

The invention relates to medicine, in particular to pulmonology, and can be used in clinical practice for the destruction of pathogenic microorganisms in the respiratory system as the most important factors in the formation and progression of exacerbation of bronchial asthma.

The property of zinc, copper and silver ions is known to inhibit the growth and reproduction of microorganisms, fungi and viruses (Moskalev Yu.I. Mineral exchange., M., Medicine, 1985, p.23-37).

The disadvantage of prescribing drugs containing ions of copper, zinc and silver orally is the low adsorption of drugs on the cell membranes of viruses, bacteria, as well as frequent allergic reactions and stomach irritation.

A known method of treating bronchial asthma, including electrophoresis (RF Patent No. 2068711).

The objective of the invention is to improve the quality of treatment of patients.

The problem is solved in that in a method of treating bronchial asthma, including the introduction of a medicinal solution by electrophoresis, a solution containing 0.5 mg / l silver, 0.5 mg / l copper and 0.5 mg / l zinc is used as a medicinal solution and electrophoresis is carried out directly in the esophagus at the level of the bifurcation of the trachea, for which a probe with a silver electrode connected to the positive pole of the electrophoresis apparatus and a solution container is inserted into the esophagus, and I impose a second electrode connected to the negative pole on the anterior abdominal wall of the esophagus at the level of the projections, electrophoresis is carried out at a current of 1.5 mA and the inflow rate of the solution to 30-40 drops per minute, for 30-40 minutes in the course of 10 treatments.

The method in general form is shown in the drawing, where: 1 - patient, 2 - ring electrode, 3 - hole in the probe for introducing a solution of silver, zinc and copper ions, 4 - anode, 5 - cathode, 6 - apparatus for electrophoresis, 7 - the dispenser of the solution, 8 - a container of dark glass, 9 - a solution of silver, copper and zinc, 10 - a silver probe olive, 11 - a conductor connecting the probe olive to the anode, 12 - a tee, 13 - a conductor connecting a ring electrode to the cathode, 14 - probe.

The study is carried out in the following sequence.

A special probe 14 is inserted into the esophagus with a silver end electrode 10 and a hole 3 to the level of the bifurcation of the trachea, to deliver a solution of silver, zinc and copper to the esophagus. The probe 14 with the electrode 10 is connected to a container of dark glass 8, into which a 0.5 mg / l solution of silver ions, 0.5 mg / l of copper ions and 0.5 mg / l of zinc ions 9, freshly prepared, are poured in an amount 500 ml Using a tee 12 and a conductor 11, the probe is connected to the positive pole (anode) 4 of the electrophoresis apparatus 6. At the projection level on the anterior abdominal wall of the patient 1 esophagus, a ring electrode 2 is fastened with a width of 20 cm, made of sheet lead and wrapped in a hydrophilic gasket. The ring electrode is connected using a conductor 13 to a negatively charged pole (cathode) 5 of the apparatus for electrophoresis 6.

The solution of silver, zinc and copper ions is fed through a probe 14 into the esophagus through the opening 3. The flow rate of the solution is 30-40 drops per minute and is regulated by the dispenser of the flow of solution 7. The current is 1.5 mA, the duration of the procedure is 30-40 minutes , on a course of 10 daily procedures.

Treatment using cavity electrophoresis of silver, zinc and copper ions was carried out in 39 patients with an established diagnosis of infectious-dependent bronchial asthma in the phase of subsiding exacerbation (15 men and 24 women) aged 21 to 65 years. All patients with a clinical manifestation of bronchial asthma had asthma attacks and cough with purulent sputum.

The results of the treatment are evaluated 2 weeks after its completion. The destruction of pathogenic microbes is judged by the bacteriological analysis of sputum.

At the same time, in 39 (100%) patients, destruction of pathogenic microorganisms in sputum was achieved - during bacteriological examination of pathogenic microorganisms in sputum it was not found, asthma attacks stopped and external respiration indicators improved.

Example 1. Patient M., 39 years old, at admission, a clinical diagnosis: Bronchial asthma, infection-dependent variant, exacerbation phase.

At admission, the patient had asthma attacks, a cough with purulent sputum, and bacteriological examination of the sputum revealed abundant growth of staphylococci and streptococci. After treatment, asthma attacks and coughing stopped on day 8 after treatment. After 2 weeks during the control bacteriological examination of sputum, microorganisms were not detected.

Complications and adverse reactions after the procedure were not observed in any patient.

The advantage of the proposed method is that it is a highly effective and safe method of destroying pathogenic microorganisms in the respiratory organs, unlike drug therapy, does not cause adverse reactions, therefore it can be used even in patients with a burdened allergic history and individual intolerance to antimicrobial chemotherapy drugs.

Claims (1)

A method of treating bronchial asthma, comprising administering a drug solution by electrophoresis, characterized in that a solution containing 0.5 mg / L silver, 0.5 mg / L copper and 0.5 mg / L zinc is used as a drug solution, and electrophoresis carried out directly in the esophagus at the level of the tracheal bifurcation, for which a probe with a silver electrode connected to the positive pole of the electrophoresis apparatus and a container with a solution is inserted into the esophagus, and a second electrode connected to the negative pole is placed on the anterior abdominal w esophageal wall at the level of the projections, electrophoresis is carried out at a current of 1.5 mA and the rate of solution Incoming 30-40 drops per minute for 30-40 minutes in the course of 10 treatments.