RU2265453C2 - Method for revaccinating children at far north against epidemic parotitis - Google Patents

Abstract

FIELD: medicine, pediatrics.

SUBSTANCE: one should form groups in 6-yr-old children who are either going to the Far North or leaving this region. In leaving group vaccine should be introduced about 7 wk before their departure, not later, as for arriving group - about 10 wk after arrival, not earlier. One should follow these mentioned time intervals to increase efficiency of immunization against parotitis due to child's body adaptation to sharply altering climatic conditions.

EFFECT: higher efficiency of revaccination.

6 ex

Description

The invention relates to medicine, more specifically to pediatrics. It can be used to revaccinate children 6 years old and older, living in the Far North, against mumps.

A known method of mass revaccination of mumps by the introduction of live mumps vaccine (VZP) at the age of 6 years [New calendar of vaccinations. - Order of the Ministry of Health of the Russian Federation No. 229 dated 06/20/2001].

However, the generally accepted method of mumps revaccination does not take into account the processes of adaptation of the organism to the conditions of the Far North. Children are vaccinated, regardless of the length of time that has elapsed since arriving from other regions. Changing the region of residence, even temporary, leads to disruption of the process of adaptation of the human body to the conditions of the Far North. This is especially true for newcomers, including children of the Far North, as these children often travel to other climatic regions of the country, as well as for new arrivals.

The known method is not effective enough and financially expensive.

The objective of the present invention is to increase the efficiency of the method of revaccination of mumps and reduce the cost of its implementation.

The essence of the invention is to revaccinate mumps with a lively mumps vaccine for children living in the Far North and over 6 years of age; according to the invention, a group of children leaving the Far North is formed and a vaccine is administered to them no later than 7 weeks before departure, and a group of children arriving from other regions are given a vaccine no earlier than 10 weeks after arrival.

Changes in specific immune reactivity that occur in the child’s body when climate conditions change, reduce the effectiveness of vaccination. To increase the effectiveness of vaccination, an adaptation period is required before departure and after arrival in the Far North from other regions.

The method is as follows.

When scheduling the mumps revaccination schedule in the Far North, data are collected on the likely departure to other climatic zones of children over 6 years old who are to be revaccinated with ZHV, form a group of people leaving the regions of the Far North. Children of this group are given ZHV no later than 7 weeks before departure from the regions of the Far North to other climatic zones. After arriving in the Far North, revaccination of VZP is carried out not earlier than in 10 weeks.

In total, in the conditions of the Far North, 621 people were vaccinated with HPV according to the proposed method. An immunological examination conducted a year later showed that the highest rates of anti-mumps immunity were found in children revaccinated with a lively mumps vaccine no later than 7 weeks before departure and no earlier than 10 weeks after arrival in the Far North.

Example 1. Sukharev A., at the age of 6 years, 7 months. HPV was revaccinated 10 weeks prior to departure from the Far North region. One year after immunization, antipartite antibodies were detected at a titer of 1:80.

Example 2. Tarasova I., aged 6 years 6 months. HPV was revaccinated 8 weeks before departure from the Far North region. One year after immunization, antipartite antibodies were detected at a titer of 1: 160.

Example 3. Aronov N., aged 7 years old, was revaccinated with HPV 4 weeks before departure from the Far North region. One year after immunization, antipartite antibodies were detected at a titer of <1:10 (seronegative).

Example 4. Kondratiev I., at the age of 7 years 4 months, was revaccinated 8 weeks after arrival in the Far North. One year after immunization, antipartite antibodies were detected at a titer of <1:10 (seronegative).

Example 5. Terekhova L., at the age of 6 years, 6 months. HPV was revaccinated 10 weeks after arrival in the Far North. One year after immunization, antipartite antibodies were detected at a titer of 1: 160.

Example 6. Dorokhov I., aged 6 years, 3 months, revaccinated 11 weeks after arrival in the Far North. One year after immunization, antipartite antibodies were detected at a titer of 1: 320.

The result of using the proposed method:

- the effectiveness of revaccination against mumps increases, this leads to a decrease in the incidence of mumps in vaccinated children and the cost of their treatment.

- reduced material costs for revaccination against mumps by reducing the duration of the immunization season, transport resources (helicopters, fuel).

Claims (1)

A method of revaccinating children in the Far North against mumps, which consists in administering a live mumps vaccine to children over the age of 6, characterized in that they form a group of children leaving the Far North and administer the vaccine no later than 7 weeks before departure, and a group of children who arrived from other regions, and give them a vaccine no earlier than 10 weeks after arrival.