RU2264711C1 - Composition for seed pickling and method for controlling of plant diseases - Google Patents

Abstract

FIELD: agriculture.

SUBSTANCE: invention relates to composition for seed pickling in form of water suspension concentrate containing thebuconazole and thiabendazole in ratio from 20:1 to 1:20 as active ingredients, nonionic and anionic surfactants, thickener, antifreeze, antifoaming agent, conserving agent, pigment, mineral or vegetable oil, lubricating agent, and water. Preparation of present invention has long shelf-life, freeze resistance, heat aging stability, beneficial effect on plant germination and harvest, and high biological activity. Method for controlling of plant diseases also is disclosed.

EFFECT: seed pickling composition of improved quality.

6 cl, 6 tbl, 5 ex

Description

The present invention relates to a new composition for seed dressing containing tebuconazole and thiabendazole as active active ingredients, more precisely, to a new formulation in the form of an aqueous suspension concentrate, which includes, in addition to the active substances, the components necessary for the preparation of this formulation.

Tebuconazole is the common name for the active substance of a broad-spectrum systemic fungicide (formula I) - (RS) -1- (4-chlorophenyl) -3- (1,2,4-triazol-1-yl-methyl) -4,4- dimethyl pentan-3-ol. Tebuconazole seed dressing is known under the trademark Raxil® (Bayer trademark.) (See EP 0040345, US Pat. No. 4723934, DE OS3333411, Pflanzenschutz Nachr Bayer, 40.2.81-129).

Thiabendazole - the common name for the active ingredient of contact action fungicide (Formula II) is 2- (4 ^'- thiazolyl) benzimidazole, first obtained by Merck & Co. .

It is known that both tebuconazole and thiabendazole are widely used in combination with other fungicides or substances with different activity, including for presowing seed treatment. This allows you to expand the spectrum of action of the drugs, as well as to some extent counteract already acquired resistance to individual active substances (See, for example, EP 0275013, EP 0316970, EP 0393746, EP 0423566, EP 0487451, EP 0897665, EP 0271579, US Pat. No. 4906648).

Regarding the popularity of mixtures of tebuconazole and thiabendazole, the microbicidal combination of tebuconazole and thiabendazole, which is added to the starting components during the polymerization to protect the resulting technical materials, is described in EP 0522393. EP 0539332 mentions the possibility of using a mixture of thiabendazole and tebuconazole to protect onions from disease caused by the pathogen Sclerotium cepivorum. There is no information about the preparative forms and their effectiveness against plant pathogens in these sources.

The closest to the present invention in technical essence is a composition for dressing seeds in the form of a water-suspension concentrate containing as active active substances (E) -1- (2,4-dichlorophenyl) -4,4-dimethyl-2- (1, 2,4-triazol-1-yl) 1-penten-3-ol (diniconazole) and 2- (4 thiazolyl) benzimidazole (thiabendazole) in a ratio of 1-2: 2-1 in combination with other components providing the necessary consumer properties preparation as a seed disinfectant. This composition (prototype), described in the patent of the Russian Federation No. 2206204, is a highly effective drug that protects crops from a wide range of diseases, however, it has certain disadvantages.

Firstly, the presence of about 20% (+) in the commercial diniconazole, an optical isomer with herbicidal and retardant properties, has a certain negative effect on the sowing qualities, growth and development of plants, especially in the early stages. In addition, the very necessity of using an optically active (-) E enantiomer in order to obtain additional technological operations in a composition leads to a rise in the cost of the drug.

Secondly, the drug was not stable enough under long-term storage at low and high temperatures.

And finally, the indicators of the retention of the drug on the seeds during storage were not high enough.

These disadvantages are deprived of a new improved composition for seed treatment in the form of a water-suspension concentrate, which is an object of the present invention.

In the composition for etching in accordance with the present invention, the active ingredients used are tebuconazole and thiabendazole in a ratio of 20: 1-1: 20 with an active substance content of from 2.0 to 40.0 wt.%.

In contrast to the prototype, instead of diniconazole in the form of the (-) Е enantiomer, the composition contains its close structural analogue - tebuconazole. Unlike diniconazole, tebuconazole is recommended for use as a 50:50 racemic mixture of (-) - S and (+) - R optical isomers. As experiments showed, the sowing qualities of the seeds treated with the new seed dressing improved. It was also possible to expand the range of ratios of active active substances and their content in preparative form.

Improving the stability of the drug under long-term storage at high and low temperatures was achieved due to the partial or complete replacement of propylene glycol with glycerol, which is introduced in an amount of from 0.5 to 20.0 wt.%. In addition to lowering the freezing point, glycerin in the new composition plays the role of a "gravitational" component, which ensures equalization of the densities of all components contained in it. In addition, glycerin is a homogenizing agent for the mineral or vegetable oil to be added to the composition.

The addition of a mineral or vegetable oil in the dressing formula in an amount of up to 15 wt.% Ensures the formation of a uniform film on the treated seeds, which leads to a uniform distribution of fungicides over the entire surface of the grain.

It also turned out that, along with the addition of oil, the introduction of a small amount of dibutyl or dioctyl phthalate (up to 5 wt.%), The so-called “oiling agents” in the formulation, increases the retention of the dressing agent on the seed surface and increases the resistance of the pickled seeds to mechanical abrasion. Often after repeated pouring, or simply during storage of the pickled seeds, dye and fungicide fall off from them, which further reduces the resistance of crops to various diseases. Field tests have shown that after the above components are introduced into the composition, the resulting film is able to withstand prolonged mechanical abrasion without changing the fungicidal activity.

As wetting agents, dispersants, thickeners and antifoams, the patented composition, in addition to the components specified in the prototype, may also contain their analogues in chemical structure and nature of action, which are interchangeable when used for their intended purpose.

Other non-ionic surfactants from the group of polyethoxylated and polyethopropoxylated fatty alcohols and alkyl phenols, such as Vitconol NP80 (a trademark of the company AKZO-Nobel) (Akzo Nobel Surface Chemistry LLC Witconol NP-80 / Ethoxyleted Nonyl Phenol, turned out to be wetting agents, in addition to Rodasurf 860 / P) ), Ijepal BC10 (trademark of Rhodia) (Surfactants and Specialites for Plant Protection, Rhodia) and the well-known domestic emulsifiers OP-7 and OP-10 and Neonol (Surfactants. Handbook edited by A.A. Abramzon and G.M.Gaevoy. Leningrad, "Chemistry", 1979; Surface-active substances TVA and Compositions. Reference book under the editorship of M.Yu. Pletnev, Moscow, Klavel firm, OOO 2002).

As dispersants, in addition to Soprofor PL, other anionic surfactants from the group of amine salts of di- or tristyrylphenylpolyglycol esters of phosphoric or sulfuric acids can be used, such as Soporfor 3D / 33, Soporfor 4D / 384 and Soporfor DSS / 7, which are also interchangeable for this formulations (Surfactants and Specialites for Plant Protection, Rhodia).

Other polysaccharides, including cellulose thickeners, such as Bermocoll® (Akzo-Nobel trademark), Akzo-Nobel (ethoxylated cellulose ethers) (Brief technical description of Bermocoll®. Cellulose thickeners, can be used as thickeners other than Rhodopol 23). Akzo Nobel) and domestic carboxymethyl or carboxyethyl cellulose (Surfactants. Handbook edited by A.A. Abramzon and G.M. Gaeva. Leningrad, Chemistry, 1979).

In addition to Rodorsil, it was possible to use Penta 469, a domestic polydimethylsiloxane defoamer, as an anti-foaming agent.

It also turned out that the composition of the new composition allows the use of not only water-soluble dyes, such as Cationic red 2C, but also water-insoluble, so-called varnishes, including Lak Rubin 2SK and Lak Rubin SK, which are calcium salts of 2-hydroxy-4- [ (4-methyl-2-sulfo (phenyl)] - azo-2-naphthalene carboxylic acid (GOST 7436-74).

When varnishes are added to the composition, it remains homogeneous, and when a dressing agent is applied to the grain, uniform dispersed coloring of the etched material is achieved.

As a preservative in the new composition, the same Cobate C® (a trademark of Rhodia) or its full analogue Glocill (a trademark of Rhome and Haas) was used.

Thus, the object of the present invention is a new composition for seed dressing in the form of a water-suspension concentrate containing, as active substances, a mixture of tebuconazole (I) and thiabendazole (II) in an amount of 2.0-40.0 wt.%, With a ratio of I : II 1.0: 20.0 to 20.0: 1.0.

As a wetting agent, the composition contains at least one nonionic surfactant selected from the group of polyoxyethylated or polyethopropoxylated alcohols or polyoxyethylated alkyl phenols, including Rodasurf 860 / P, Vitkonol NP 80, Izhepal BC 10 and OP-7 or OP-10 or Neonol, in an amount of 0.1 to 5.0 wt.%.

As a dispersant, the composition contains at least one anionic surfactant selected from the group of ammonium salts of di- or tristyrylphenylpolyglycol esters of phosphoric or sulfuric acids, including Soporfor FL, Soporfor 3D / 33, Soporfor 4D / 384, Soporfor DSS / 7 in an amount of 1, 0 to 15.0 wt.%

As thickeners, the composition may contain an anionic heteropolysaccharide Rodopol 23, or a non-ionic derivative of Bermocall cellulose in an amount of from 0.1 to 10.0 wt.% Or carboxymethyl or carboxyethyl cellulose (in terms of a 2% thickener solution).

As a preservative in the composition, hexahydro-1,3,5-tris (2-hydroxyethyl) sym.-triazine was used in an amount of up to 0.045 wt.% (Cobate C or Glokkil).

Polydimethylsiloxane (Rodorsil 426 or Penta 469) is used as an antifoam agent.

To obtain a signal color, a dye is introduced into the composition, either water-soluble (cationic red 2C) or water-insoluble (Lac Rubin SK or 2SK) in an amount of not more than 25 wt.%.

Unlike the prototype, the new composition as an antifreeze and co-solvent includes glycerin in an amount of from 0.5 to 20.0 wt.% Or its mixture with propylene glycol, the content of the latter not exceeding 10 wt.%, And the ratio of glycerol to propylene glycol is from 1 : 0.1 to 0.1: 1.

Unlike the prototype, the new composition also contains mineral (transformer, petrolatum, industrial) or vegetable oil (soybean, vegetable) in an amount of from 0.5 to 15.0 wt.%, And the so-called sizing, at least one of the phthalic esters acid (dibutyl-, dipropyl- or dioctylphthalate) in an amount of 0.01-5.0 wt.%.

The introduction of glycerol and oil into the composition, as experiments have shown, increases its aggregative stability and increases frost resistance. New drugs, unlike the prototype, can be stored without changing their properties at temperatures from minus 10 ° С to plus 35 ° С and exhibit high resistance to thermal aging.

The addition of oil and lubricants ensures uniform staining and a high degree of drug retention on the surface of the seeds, which ultimately leads to an increase in the effectiveness of their action against pathogens that cause plant diseases.

A mixture of tebuconazole and thiabendazole in various proportions, as shown by experiments, is not inferior to the prototype in terms of both level and spectrum of biological activity, despite the fact that, unlike the prototype, mixtures of active substances do not show such a significant and clearly expressed synergism with respect to pathogens of plant diseases.

Field biological tests of the patented composition showed high biological effectiveness against root rot of spring wheat and barley, and the effectiveness of the patented composition against helminthosporious rot turned out to be much higher than the effectiveness of the drug on tebuconazole (Raxil preparation) due to the presence of the second fungicide - thiabendazole. The drug also showed high effectiveness against the most dangerous diseases of crops - dusty and hard smut.

In general, it can be stated that the proposed composition of the drug based on tebuconazole and thiabendazole showed high efficacy against fungal mold pathogens (Rhizopus spp., Penicillium spp., Trichothecium spp.), Fusarium snow mold (Fusarium culmorum, F.oxysp .graminearum, F.avenacium), fusarium-helminthosporiotic rot, bacterial diseases (Pseudomonas spp., Xhanthomonas spp., Corynebacterium spp.), smut diseases (Ustilago nuda, Ustilago laevis, Tilletiaeiecheiecheiecheiecheiecheiecheiecheiecaeothelieteiecheiecaeothelietheiecheieciothelieteieciotheliothelieteiecheiothecaetiotheca ) cereal crops, corn and millet.

The experiments also showed the beneficial effect of the new drug on the size and quality of the wheat and barley crops.

Another object of the invention is a method of combating plant diseases by presowing treatment of seeds with an effective amount of the composition described above.

The following are examples illustrating but not limiting the invention.

Example 1. Obtaining a composition for seed treatment.

Metered amounts of propylene glycol, glycerin, a wetting agent, a dispersant and an anti-foaming agent are fed into a heated reactor and mixed thoroughly. To the resulting mixture add tebuconazole, thiabendazole, oil, sizing and water and mix thoroughly. The resulting mixture is ground in a Dino-Mill bead mill until a particle size of less than 5 microns is achieved. The milled suspension is fed into a container into which a calculated amount of a previously prepared 2% thickener solution is added, containing the required amount of preservative and a calculated amount of dye. After adding all the components, the mixture is again thoroughly mixed.

Table 1 presents some formulations of the obtained preparations.

^and Rodasurf 860 / P

^b Soprofor 4D / 384

ⁱⁿ Rodopol 23

^Mr. Kobate

^d Cationic red 2C

^e Vaseline oil

^Well Dioctyl phthalate

^Z Rodorsil 426

^and Jazepal BC / 10

^to Soprofor FL

^l Transformer oil

^m Soprofor 3D / 33

^Mr. Luck Rubin SK

^o Industrial oil

ⁿ Bermocall

^p Dibutyl phthalate

^from Penta 469

^t Vitconol NP 80

ⁱⁿ Soprophor DSS / 7

^f Glockkil

^x Lac Rubin 2SK

^c dipropyl phthalate

^h OP-7

^w Carboxymethyl cellulose

^Щ Carboxyethyl cellulose

^s Soybean oil

The following formulations can be given as examples of the formulations obtained:

Composition 1.

Tebuconazole - 100 g / l Thiabendazole - 100 g / l Propylene glycol - 30 g / l Glycerol - 60 g / l Soprofor 4D / 384 - 40 g / l Rodasurf 860 / P - 20 g / l Vaseline oil - 40 g / l Antifoam Rodorsil 426 - 20 g / l Rhodopol 23 (2% solution) - 1.0 g / l

Table 1
The compositions of the obtained formulations Content, g / l Sample Number Contained. in wt.% Names. components 1 2 3 4 5 6 7 8 nine 10 Tebuconazole 100 thirty fifty 60 80 150 10 200 170 200 1-20,0 Thiabendazole 100 80 fifty 80 thirty twenty 200 10 150 200 1-20,0 Propylene glycol thirty - - 100 - 100 100 twenty 100 thirty 0-10,0 Glycerol 60 100 100 fifty 150 10 150 200 fifty 5,0 0.5-20.0 Wetting agent 20 ^a 10 ^a 10 ^and 20 ^a 40 ^a 50 ^t 10 ^t 1 ^a 5 ^t 3 ^t 0.1-5.0 Dispersant 40 ^m 80 ^b 80 ^to 80 ^b 120 ^m 60 ^y 150 ^m 150 ^b 10 ^y 150 ^b 1.0-15.0 Thickener 2% solution 1.0 ⁱⁿ 10 ⁱⁿ 40 ⁱⁿ 30 ⁱⁿ 0.6 ^p 2 ^p 100 ^sh 50 ^u 80 ⁱⁿ 100 ⁱⁿ 0.1-10.0 Preservative 0.45 ^g 0.042 ^g 0.42 ^g 0.3 ^g 0,0 0.20 ^f 0,1 ^f 0.15 ^g 0,03 0.04 ^g 0,0-0,045 Dye 100 ^d 100 ^d 200 ^d 100 ⁿ 250 ⁿ 80 ^x 250 ^x 50.0 ^d - 50 ⁿ 0-25.0 Oil 40 ^e 100 ^e 150 ^l 50 ^l 80 ^about 30 ^e 35 ^b 10 ^l 5 ^l 100 ^e 0.5-15.0 Sizing 0.1 ^g 1 ^g 1 ^g 1 ^g 30 ^r 5 ^c 45 ^c 50 ^r 30 ^r 50 ^c 0.01-5.0 Anti-foaming agent 20 ^s 40 ^s 30 ^s 4 ^s 0.4 ^s 1 ^s 20 ^s 30 ^s 35 ^s 40 ^s 0.05-4.0 Water Up to 1 liter Up to 1 liter Up to 1 liter Up to 1 liter Up to 1 liter Up to 1 liter Up to 1 liter Up to 1 liter Up to 1 l Up to 1 liter Up to 1 liter

Dioctyl phthalate 0.1 g / l Cationic Red SC 100 g / l Preservative 0.45 g / l Water up to 1 liter

Physico-chemical characteristics of the drug:

Viscosity 1100 MPa * s Density 1096 kg / m ³ pH 8.3 Dispersion 88% of particles less than 4 microns Stability 5% suspension 95%

Composition 2.

Tebuconazole 30 g / l Thiabendazole 80 g / l Glycerol 100 g / l Soprofor 4D / 384 80 g / l Rodasurf 860 / P 10 g / l Vaseline oil 100 g / l Antifoam Rodorsil 426 40 g / l Rhodopol 23 (2% solution) 10 g / l Dioctyl phthalate 1 g / l Cationic red 2SK 100 g / l Preservative 0.042 g / l Water up to 1 liter

Physico-chemical characteristics of the drug:

Viscosity 940 MPa * s Density 1076 kg / m ³ pH 8.2 Dispersion 92% of particles less than 4 microns. Stability 5% suspension 97%

Composition 3.

Tebuconazole 50 g / l Thiabendazole 50 g / l Glycerol 100 g / l Soprofor FL 80 g / l Ijepal BC / 10 10 g / l Transformer oil 150 g / l Antifoam Rodorsil 426 30 g / l Rhodopol 23 (2% solution) 40 g / l Dioctyl phthalate 10 g / l Preservative 0.42 g / l Cationic red 2SK 200 g / l Water up to 1 liter

Physico-chemical characteristics of the drug:

Viscosity 890 MPa * s Density 1078 kg / m ³ pH 8.3 Dispersion 91% of particles less than 4 microns Stability 5% suspension 91%

Composition 4.

Tebuconazole 60 g / l Thiabendazole 80 g / l Propylene glycol 100 g / l Glycerol 50 g / l Soprofor 4D / 384 80 g / l Rodasurf 860 / P 20 g / l Transformer oil 50 g / l Antifoam Rodorsil 426 4 g / l Rhodopol 23 (2% solution) 30 g / l Dioctyl phthalate 1 g / l Lac Rubin SK 100 g / l Preservative 0.3 g / l Water up to 1 liter

Physico-chemical characteristics of the drug:

Viscosity 1090 MPa * s Density 1075 kg / m ³ pH 7.7 Dispersion 89% of particles less than 4 microns Stability 5% suspension 98.5%

Composition 5.

Tebuconazole 80 g / l Thiabendazole 30 g / l Glycerol 150 g / l Soprofor 3D / 33 120 g / l Rodasurf 860 / P 40 g / l Industrial oil 80 g / l Antifoam Penta 469 4 g / l Bermocall 0.6 g / l Dibutyl phthalate 30 g / l Lac Rubin SK 250 g / l Water up to 1 liter

Physico-chemical characteristics of the drug:

Viscosity 1320 MPa * s Density 108 8 kg / m ³ pH 8.9 Dispersion 94% of particles less than 4 microns Stability 5% suspension 89%

Composition 5 *

Tebuconazole 80 g / l Thiabendazole 30 g / l Glycerol 150 g / l Soprofor 3D / 33 120 g / l Neonol 40 g / l Industrial oil 80 g / l Antifoam Penta 469 4 g / l Bermocall 0.6 g / l Dibutyl phthalate 30 g / l Lac Rubin SK 250 g / l Water up to 1 liter

Physico-chemical characteristics of the drug:

Viscosity 1410 MPa * s Density 1092 kg / m ³ pH 8.6 Dispersion 93% of particles less than 4 microns Stability 5% suspension 87%

Composition 6.

Tebuconazole 150 g / l Thiabendazole 20 g / l Propylene glycol 100 g / l Glycerol 10 g / l Soprofor DSS / 7 50 g / l Vitconol NP 80 50 g / l Vaseline oil 30 g / l Antifoam - Rodorsil 426 1 g / l Bermocall 2 g / l Dipropyl phthalate 5 g / l Lac Rubin SK 80 g / l Preservative 0.2 g / l Water up to 1 liter

Physico-chemical characteristics of the drug:

Viscosity 1280 MPa * s Density 1093 kg / m ³ PH 9,4 Dispersion 86% of particles less than 4 microns Stability 5% suspension 90%

Example 2. Assessment of the stability of drugs during storage.

To assess the possibility of storing drugs for 2 years at a temperature of minus 10 to plus 35 ° C, the following tests were carried out:

1. Test for accelerated storage: the preparations were kept in a thermostat at plus 54 ° C for 2 weeks (CIPAC MT 46 technique);

2. Test for frost resistance: the preparations were kept in a thermostat at a temperature of minus 15 ° С for 10 days (GOST 9.707-81 and Surfactants and Specialties for Plant Protection, Rhodia);

3. Heat aging test: the preparations were kept in a thermostat at a temperature of plus 45 ° С for 60 days (GOST 9.707-81 and Surfactants and Specialites for Plant Protection, Rhodia);

The repetition of tests is 3 times.

The viscosity of the preparations, both before and after storage, was determined on a Brookfield viscometer, stability was determined according to GOST 16484-79 and the CIPAC MT161 Method, dispersion was determined on a Fritsch-Analysette 22 laser particle analyzer. The results are presented in Table 2.

As can be seen from table 2, the new composition surpasses the composition of the prototype in terms of frost resistance and resistance to thermal aging.

table 2
EVALUATION OF STABILITY OF DRUGS DURING STORAGE №№ A drug Type of test physical and chemical indicators Viscosity, MPa * s 293 K Density kg / m ³ , 293 K pH Dispersion,% The stability of 5% suspension,% Crystallization temperature, ° С 1 Sample No. 1 Before storage 1110 1096 8.3 <4 μm - 88% 95 Minus 22 After storage at + 54 ° C for 14 days 1180 1092 8.3 <4 microns - 85% 95.8 After storage at -15 ° C for 10 days 1160 1092 8.2 <4 microns - 85% 96.0 After storage at + 45 ° C for 60 days 1193 1093 8.3 <4 microns - 84% 95.3 2 Sample No. 2 Before storage 940 1076 8.2 <4 μm - 92% 97 Minus 25 After storage at + 54 ° C for 14 days 945 1078 8.2 <4 μm - 87% 96 After storage at -15 ° C for 10 days 950 1077 8.3 <4 microns - 85% 97 After storage at + 45 ° C for 60 days 945 1077 8.3 <4 μm - 88% 92 3 Sample No. 3 Before storage 890 1078 8.3 <4 μm-91% 91 Minus 12 After storage at + 54 ° C for 14 days 880 1078 8.4 <4 μm - 94% 90 After storage at + 45 ° C for 60 days 880 1071 8.0 <4 μm - 86% 91 4 Sample No. 4 Before storage 1090 1075 7.7 <4 μm - 89% 98.5 Minus 22 After storage at + 54 ° C for 14 days 1096 1075 7.8 <4 microns - 90% 98 After storage at -15 ° C for 10 days 1096 1076 7.7 <4 μm - 89% 98.2 After storage at + 45 ° C for 60 days 1097 1076 7.7 <4 microns - 90% 99.0 5 Prototype sample Before storage 1090 1052 7.6 <4 microns - 85% 95.3 Minus 19 After storage at + 54 ° C for 14 days 1080 1040 7.45 <4 microns - 74% 90.0 After storage at -15 ° C for 10 days 1020 1022 7.3 <4 microns - 60% 83,2 After storage at + 45 ° C for 60 days 1000 1020 6.4 <4 μm - 36% 60.3 The drug is stratified by 20%

Example 3. The study of biological activity in experiments in vitro (in pure cultures)

The experiments were carried out in relation to such pathogens of cereal diseases as Fusarium graminearum, Botritis cinerea and Pseudomonas atrofociens.

Seeds treated with the fungal colonies were placed in Petri dishes with the seeds etched with the preparations and kept in a thermostat for 3-5 days. At the end of the incubation, the disinfection zones of the fungal colonies were measured, comparing the growth of the colonies in the control and on the medium with the etched seeds introduced into them before and after mechanical abrasion.

For mechanical abrasion of the etched seeds, a mechanical vibrator was used, on which a sieve containing etched seeds was mounted, and a course of vibration processing was carried out for 15 minutes at a frequency of 35-50 vibrations per second.

As can be seen from table 3, the patented mixture in the form of a preparation in the form of a water-suspension concentrate had a higher fungicidal activity than a reference preparation based on tebuconazole alone (raxyl, VSK). An analysis of the resistance to shedding of seeds after mechanical action, of course, shows an improvement in these characteristics in the patented compositions compared to the standard - Raxil and the drug - the prototype based on a mixture of diniconazole and thiabendazole.

Table 3
TREATMENT HOLDER IN THE FORM OF WATER-SUSPENSION CONCENTRATES ON BARLEY SEEDS AFTER MECHANICAL WASHING A DRUG NORM,
l / ton of seeds Disinfection area around the seed, cm Pseudomonas atrofociens Fusarium graminearum Botritis cinerea To mehan. abrasion After mehan. abrasion Before mechanical abrasion After mehan. abrasion Before mechanical abrasion After mechanical abrasion Prototype drug 0.4 3.8 2.0 4.0 2.7 4,5 3,5 Composition 1 0.4 5.9 5.8 5.5 5.5 6.0 6.0 Composition 2 0.4 4.9 4.7 4.6 4,5 5.2 5.2 Composition 3 0.4 5.2 5.2 4.9 4.9 5.1 5,0 Composition 4 0.4 6.1 6.1 5.7 5.7 5.3 5.2 Composition 7 0.4 5.7 5,6 5.2 5.2 5,6 5.5 RAXIL 0.4 0 0 0 0 0 No pickling control 0 0 0 0 0 0

Example 4. The effect of dressing agents on sowing qualities, growth and development of barley.

The experiments were carried out in laboratory conditions in accordance with the "Methodical Guide to conducting greenhouse-field testing of seed dressers, fungicides and bactericides", Cherkasy, 1996. The seeds treated with the indicated consumption rates were checked for laboratory germination by sowing in rolls, controlling the number of germinated seeds and thus calculating the seed germination percentage. Then, for seedlings after 14 days of growth, the length of the stem and root system were determined, then the plant mass was dried and the dry weight of the stems and seedlings was determined in comparison with the control. Seeds were etched using semi-dry etching with a consumption of the pickling solution - 10-11 l / ton of seeds.

Table 4 shows the results of experiments according to which the patented composition increases seed germination both in comparison with the prototype and in comparison with the standard (drug based on tebuconazole Raxil, SC). At the same time, the patented composition has some growth-stimulating effect in comparison with the prototype - a preparation based on diniconazole and thiabendazole.

Table 4
INFLUENCE OF PROTECTORS ON SEEDING QUALITIES, GROWTH AND DEVELOPMENT OF BARLEY PLANTS A DRUG Norm, l / t of seeds Laboratory germination,%

Control, no processing - 98 4/100 6/100 The prototype drug 0.4 75 3,5 / 85 5.5 / 90 Composition 1 0.4 90 5.5 / 135 8.0 / 118 Composition 2 0.4 94 5.9 / 148 8.5 / 128 Composition 3 0.4 92 5.3 / 130 7.3 / 115 Composition 4 0.4 96 5,6 / 136 7.6 / 116 Composition 5 0.4 88 4.9 / 126 7.0 / 112 Composition 6 0.4 90 5.2 / 133 8.0 / 117 Composition 7 0.4 92 6.3 / 139 8.2 / 120 Composition 8 0.4 85 5.3 / 135 7.4 / 114 Raxil 0.4 85 5.5 / 120 8.0 / 110

Example 5. Assessment of biological activity against root rot and smut diseases in field trials.

The experiments were carried out on spring wheat (s.Enita) and spring barley (variety Zazersky) in the Moscow region and the southern foothill zone of the Krasnodar Territory.

The laying and conducting of the experiments was carried out according to the "Methodological guidelines for state testing of fungicides, antibiotics and seed dressers", M., 1985. Wheat and barley seeds were etched in a PS-10 pickling machine with a consumption rate of the pickling solution of 10 liters / ton of seeds . Seeds were planted in areas of 10 m ² . The degree of affection with fusarium and helminthosporious rot at various development phases was controlled by digging up 10% of the plants and assessing the degree of affection of the crops. After ripening, continuous manual harvesting of each plot was carried out and the total crop yield was evaluated.

The results are presented in tables 5 and 6.

It was found that the patented drug on the basis of tebuconazole and thiabendazole has a high degree of suppression of helminthosporious and fusarium rot on spring wheat and barley, and the introduction of thiabendazole in the drug significantly reduces the spread of helminthosporious rot in comparison with the single-component drug based on tebuconazole Rucaxonazole.

The efficiency of suppressing dusty and smut smut on wheat is 100%, the suppression of fusarium root rot is 95-97%.

Table 5
BIOLOGICAL EFFICIENCY OF THE COMPOSITION FOR TREATMENT OF SEEDS AGAINST ROOT ROTS OF SPRING WHEAT OF VARIETY ENITA AND SPRING BARLEY VARIETY ZAZERSKY 85 (2003 tests) A drug Consumption rate, l / t Spring wheat, grade Enita Spring barley, grade Zazersky 85 Natural Infectious Background Natural Infectious Background Total prevalence% The defeat of Fusarium rot,% The prevalence of helminthosporic rot,%. Total prevalence,% The defeat of Fusarium rot,% The prevalence of helminthosporic rot,% Phase Control - The Second Half of Tillering 24.7 13.3 11,4 21.0 4.2 16.8 Composition 1 0.4 4.7 1,1 3.6 3.6 0.4 3.2 Composition 2 0.4 7.9 1.7 6.2 6.6 1,1 5.5 Composition 3 0.4 5.8 1.4 4.4 4.9 0.9 4.0 Composition 4 0.4 4.3 1.4 2.9 3,7 0.4 2.9 Composition 7 0.4 8.6 2.1 6.5 6.3 1.3 5,0 Composition 8 0.4 7.5 1.4 6.1 5.3 1,2 4.3 Prototype drug 0.4 7.6 2,5 5.1 6.8 1.9 4.9 RAXIL 0.4 13.3 1.4 11.9 7.8 1.4 6.4 Phase-milk ripeness control 37.5 23.8 13.7 88.8 7.7 81.1 Composition 1 0.4 13.7 4.9 8.8 39.5 0.3 39.2 Composition 2 0.4 18.0 9,4 8.6 67.3 0.8 66.5 Composition 3 0.4 16.3 6.8 9.5 48,4 0.5 51,2 Composition 4 0.4 12.3 4.0 8.3 30.6 0.5 30.1 Composition 7 0.4 19.6 9.9 9.7 45.3 0.8 44.5 Composition 8 0.4 19.5 9.6 9.9 69.3 0.6 68.7 Drug prototype 0.4 20,4 9.9 10.5 70.3 2,4 67.9 RAXIL 0.4 20.6 11.2 9.2 75.0 0.9 74.1

Table 6
The effectiveness of the composition for seed treatment against wheat diseases (Variety Enita, 2004 test) CULTURE A DRUG Consumption rate, l / ton of seeds Harmful object Biological efficiency,% Productivity, t / ha Spring wheat Composition 1 0.4 Helminthosporious root rot 56 Composition 2 0.4 47 Composition 3 0.4 51 Composition 4 0.4 66 Composition 7 0.4 57 Composition 8 0.4 49 Prototype drug 0.4 48 RAXIL 0.4 thirteen Composition 1 0.4 Fusarium Root Rot 99 Composition 2 0.4 95 Composition 3 0.4 97 Composition 4 0.4 99 Composition 7 0.4 96 Composition 8 0.4 95 Prototype drug 0.4 92 RAXIL 0.4 97 Composition 1 0.4 Fusarium-helminthosporious rot 72 67 Composition 2 0.4 65 61 Composition 3 0.4 67 65 Composition 4 0.4 77 68 Composition 7 0.4 66 60 Composition 8 0.4 62 60 Prototype drug 0.4 63 61 RAXIL 0.4 fifty 53 Composition 1 0.4 Dusty and hard smut 100 45.6 Composition 2 0.4 100 41.7 Composition 3 0.4 100 43 Composition 4 0.4 100 43.8 Composition 7 0.4 100 42.1 Composition 8 0.4 100 41.9 Prototype drug 0.4 100 43.8 RAXIL 0.4 100 40,2

Claims (6)

1. A composition for seed dressing in the form of a water-suspension concentrate containing, as active active substances, a triazole series fungicide and 2- (4'-thiazolyl) benzimidazole (thiabendazole) (II), nonionic and anionic surfactants as a wetting agent and dispersant, respectively, anti-foaming agent, thickener, antifreeze and dye, preservative and water, characterized in that the composition contains (RS) -1- (4-chlorophenyl) -3- (1,2,4-triazol-1-yl- as a fungicide of the triazole series methyl) -4,4-dimethyl-pentan-3-ol (tebuconazole) (I), the ratios active ingredients I: II can vary from 20: 1 to 1:20, as antifreeze - glycerin or its mixture with propylene glycol in a ratio of 1: 0.1 to 0.1: 1, and also additionally contains mineral or vegetable oil and lubricants, which use phthalic acid esters, in the following general ratio of components, wt.%: Tebuconazole 1-20 Thiabendazole 1-20 Wetting agent 0.1-5.0 Dispersant 1,0-15 Thickener, 2% solution 0.1-10.0 Glycerol 0.5-20.0 Propylene glycol 0-10,0 Mineral or vegetable oil 0.5-15.0 Sizing 0.01-5.0 Anti-foaming agent 0.05-4.0 Dye 0-25.0 Preservative No more than 0,045 Water Up to 100 2. The composition for seed dressing according to claim 1, characterized in that as a wetting agent it contains at least one nonionic surfactant selected from the group of polyoxyethylated and polyethopropoxylated fatty alcohols or alkyl phenols, including Rodasurf 860 / P, Vitconol NP80, Ijepal BC 10 and OP-7 or OP-10, Neonol, and as a dispersant - at least one anionic surfactant selected from the group of ammonium salts of di- or tristyrylphenylpolyglycol esters of phosphoric or sulfuric acids, including SoporFL FL, Soporfor 3D / 33, Soporf 4D / 384 , Soprofor DSS / 7. 3. A seed dressing composition according to claim 1, characterized in that it contains a polysaccharide selected from the group Rodopol 23, Bermocall, carboxymethyl or carboxyethyl cellulose as a thickener, and hexahydro-1,3,5-tris as a preservative (2 -hydroxyethyl) sym triazine. 4. The seed dressing composition according to claim 1, characterized in that as a lubricant it contains one of the phthalic acid esters, such as dipropyl phthalate, dibutyl phthalate or dioctyl phthalate, polydimethylsiloxane selected from Rodorsil 426 and Penta 469 as antifoam, and as a dye, cationic red 2C, or Lac Rubin SK, or Lac Rubin 2SK. 5. The composition for seed dressing according to claim 1, characterized in that the amount of active active substance in it is from 2 to 40 wt.%. 6. A method of combating plant diseases by pre-sowing seed treatment, characterized in that the seeds are treated with an effective amount of a composition according to claims 1-5.