RU2203100C2 - Device for intrabone injection of medicines into mandible - Google Patents

Abstract

FIELD: medicine. SUBSTANCE: invention can be used in oncology and surgery for injection of cytostatics and antibiotics into mandible at oncological and inflammatory diseases of mouth cavity. In proposed device end of handle is made in form of cannula of syringe with two diametrically opposite flat projections at cone base fixed by sharp mandrin on which hollow needle with outer thread is installed. Said needle has cylindrical hole of diameter equal to diameter of mandrin changing in upper part into cone hole corresponding to cannula of syringe, and two slots by means of which needle is tightly fixed on two projections of handle. EFFECT: improved curing effect. 1 ex, 1 dwg

Description

 The invention relates to medicine, namely to oncology and surgery, and can be, in particular, used for the introduction of cytostatics and antibiotics in the lower jaw for cancer and inflammatory diseases of the oral cavity.

 The analogue is known - a prototype - a needle for puncture of the bone marrow cavity of the tubular bone, consisting of a thick injection needle with a mandrel equipped with a handle and having a spike in the lower part that falls when the mandrel is inserted into the slot of the needle nozzle (Vinogradov V.V. puncture of bones. "Surgery, 1948, 9, p. 13-14).

A disadvantage of the known prototype is that
- when the needle is in the bone for a long time, the tightness is broken;
- there is a leakage of the drug substance, it is difficult to control the depth of entry of the needle into the bone tissue;
- When using the needle requires significant physical effort.

 The inventive device for intraosseous administration of drugs into the lower jaw "Needle VM Ivanova" is new and is not described in the literature.

 The aim of the invention is to increase the therapeutic effect.

 The basis of the invention is the task of intraosseous administration of drugs in the lower jaw.

 The problem is solved in that in the inventive device, the end of the handle is made in the form of a syringe cannula with two diametrically located flat protrusions at the base of the cone, motionlessly fixed with a sharpened mandrel, on which a hollow needle with an external thread is installed, having a cylindrical hole equal to the diameter of the mandrel and passing in the upper parts in the conical, corresponding to the cannula of the syringe, and there are also two grooves with which the needle is tightly fixed on two protrusions of the handle, and the mandrin protrudes from the needle by 3-5 mm.

 Using the proposed device, cytostatics and antibiotics are introduced into the bone tissue. At the same time, high concentrations of these drugs are created at the site of the lesion, which leads to an increase in the therapeutic effect with a sharp simultaneous decrease in local and general cytostatic complications (vomiting, hair loss, damage to the mucous and blood-forming organs).

 In the proposed device, the end of the handle is made in the form of a cannula of a syringe so that the needle can be fixed both on the handle and on the syringe. It also provides two diametrically located flat protrusions included in two grooves of the needle to transmit rotational movement from the handle to the needle.

 The mandrin is fixedly mounted on the handle in order to prevent clogging of the needle when screwing it into the bone tissue, and the sharpened mandrin 3-5 mm protrudes from the needle to puncture and easily carry the needle into the bone tissue.

 The hollow needle has an external thread, which allows it to be well fixed and tightly in contact with bone tissue, which eliminates leakage of medications.

The proposed invention is illustrated in the drawing, where
1 - pen
2 - the ledge of the handle, the groove of the needle
3 - needle
4 - mandren
The proposed device was tested during 1999-2000. in the Regional Oncology Center of Astrakhan on 5 corpses and 10 patients with cancer of the mucous membranes of the oral cavity.

 The following is the result of testing.

 Example: Patient R., born in 1937, medical history 3130, was admitted to the Department of “Tumors of the Head, Neck and Soft Tissues” on July 25, 2000 with a diagnosis of Tongue Cancer of the II stage, condition after radiation therapy.

 After the necessary examination and preparation on August 2, an operation was performed - resection of the tongue, the bottom of the oral cavity with plastic-muscular skin grafting with the inclusion of the pectoralis major muscle on the right, a sheath-fascial excision of the neck tissue on the right.

 Given radiation therapy before surgery, a large amount of surgery and for the prevention of osteomyelitis, on August 2, a device for intraosseous administration of drugs was introduced into the lower jaw.

 For this, anesthesia was performed with a solution of 0.25% novocaine of the skin, subcutaneous tissue, periosteum of the injection site of the device (needle). An external thread hollow needle is mounted on a handle with a mandrin. By translational-rotational movements with a moderate load on the handle (1) of the device, the needle (3) following the sharp mandrin (4) is inserted to a certain depth due to the thread along the outer contour.

 The pen together with the mandrel was removed and, first, 10 ml of 0.25% novocaine and then 1.0 kefzol diluted on novocaine were introduced through a syringe through a needle.

 The introduction of novocaine and kefzol through a needle standing in the lower jaw 4 times a day lasted for 7 days. After each injection, the patient's condition improved, pain in the oral cavity disappeared, it became possible to swallow saliva and rinse his mouth.

 Despite significant microbial contamination of the oral cavity, radiation therapy before surgery, anemia in the early postoperative period, no suppuration of the wound and the development of osteomyelitis of the lower jaw were noted, which in such patients can occur up to 50% of cases.

 This is largely due to the prophylactic administration of intraosseous antibiotics.

 The introduction of novocaine improved the course of the postoperative period, reducing pain.

 The proposed device achieves an increase in the therapeutic effect, namely, given the long (7-10 days) and persistent presence of the needle in the bone tissue, multiple medications can be administered throughout the day, and in the early postoperative period, it is possible to achieve high concentrations of antibiotics in the area of the operation and cytostatics, which reduces the number of postoperative complications. The needle is versatile, self-locking, comfortable and easy to use.

 The proposed device can be recommended in wide clinical practice for the introduction of drugs into other bone structures, as well as for the prevention and treatment of both surgical and oncological diseases.

Claims (1)

 A device for intraosseous administration of drugs into the lower jaw, containing a pen with a mandrin and a hollow needle, characterized in that the end of the pen is made in the form of a syringe cannula with two diametrically located flat protrusions at the base of the cone, a fixed sharpened mandrax on which a hollow needle is installed with an external thread having a cylindrical hole equal to the diameter of the mandrel and passing in the upper part into a conical corresponding to the cannula of the syringe, and there are also two grooves, which and tightly fixed to the two lugs of the handle.