RU2258502C2 - Method for treatment of galactophoritis - Google Patents

Abstract

FIELD: medicine, surgery.

SUBSTANCE: method involves carrying out an antibacterial therapy and additional administration of curative mixture consisting of one part of dimexide, two parts of 0.5% of novocaine solution with antibiotic eliciting high the bacteriostatic activity against microflora in duct secret. Administration of this curative mixture is carried out by catheter into injured duct directly by course 1-2 times. Invention promotes to topical sanitation of mammary gland duct and reducing time of disease. Invention can be used in treatment of galactophoritis.

EFFECT: improved method for treatment.

1 ex

Description

The invention relates to medicine, namely to surgery, and is used to treat chronic inflammatory lesions of the ducts of the mammary gland (galactophoritis), usually occurring against a background of secretory mastopathy.

Galactophoritis is a fairly common disease in surgical practice, but difficult to conservatively treat. The commonly used general antibiotic therapy [4] is ineffective due to the poor permeability of the fibrous-altered walls of the duct of the breast. At the same time, there are known cases of cure of galactophorites after X-ray contrast studies of the ducts of the mammary gland using iodine contrast agents [1, 2, 3, 5]. However, intraductional administration of anti-inflammatory drugs for therapeutic purposes was not carried out due to the great difficulty of introducing a metal needle into the lumen of the duct and the frequent trauma of its walls.

The purpose of the invention: Improving the effectiveness of the treatment of chronic inflammation of the ducts of the mammary glands (galactoforitis) by the intraductal administration of therapeutic drugs.

This goal is achieved due to the fact that the medications are delivered directly to the focus of inflammation through the lumen of the duct, and the safety of the procedure is ensured by using a thin vinyl chloride tube for catheterization of the duct.

Prototypes are the use of general antibiotic therapy, as well as the method of intraductal injection of contrast fluid into the ducts of the mammary gland for diagnostic procedures.

The disadvantages of these prototypes is the following.

1. Low therapeutic efficacy of general antibiotic therapy associated with impaired permeability of the walls of the duct of the breast, due to fibrotic changes.

2. The complexity, the invasiveness of the method of intubation of the ducts of the mammary gland with a metal needle.

Procedure: On the dressing table in the supine position, after antiseptic treatment of the skin of the nipple to the halos, the mouth of the duct of the mammary gland affected by galactophoritis is identified. At the mouth of the duct, a catheter is inserted at various depths depending on the galactographic pattern. The transparent walls of the vinyl chloride tube allow you to control the accuracy of getting into the affected duct by the nature of the secret that fills the distal sections of the catheter. From a syringe connected to the opposite end of the catheter, 0.5 to 2 ml of the treatment mixture is administered, consisting of: 1 part of dimexide + 2 parts of novocaine 0.5% + antibiotic with high bacteriostatic activity to the microflora of the duct secretion. Then the catheter is removed, and the duct is removed by compression of the mammary gland from the injected solution along with its stagnant contents. This procedure is performed in the same sequence several times until the effect of "pure water". In conclusion, 0.5 to 2 ml of the treatment mixture is introduced depending on the capacity of the channel of the duct and the catheter is removed. After a week, the effectiveness of the procedure is studied and, if signs of pathological secretion are preserved, the procedure is usually repeated no more than 1-2 times.

This technique has been tested on 144 patients.

97.9% is a complete cure.

2.1% - marked clinical improvement.

The duration of treatment averaged two weeks.

An example implementation of the method.

Patient K. with diffuse bilateral secretory mastopathy complicated by galactophoritis was prescribed general antibiotic therapy (erythromycin 5 days) and local antibiotic therapy in the form of retro-mammary novocaine blockade (two on each side). After the treatment, a pronounced therapeutic effect was noted, however, pathological secretion continued to be observed from one duct. A bacteriological examination of the abnormal fluid was performed, Staphylococcus aureus, sensitive to the antibiotic - kanamycin - was sown. Sanitized duct was sanitized according to the proposed method, after two procedures there were no signs of pathological secretion.

Sources of information

1. Bukhman F.I., Mikhailovskaya M.V., Bobrov M.Ya. Ductography, as a method that clarifies the diagnosis of secreting mammary gland. // Bulletin of radiology and radiology. - 1981 - No. 2.

2. Mitasov I.G., Tilenko I.A. Treatment of secreting mammary gland with drug obliterapy. // Surgery. - 1979, v. 6, - p. 103.

3. Rozhkova N.I. The diagnostic value of a contrast study of the ducts of the mammary gland. // Bulletin of radiology and radiology. - 1981. - No. 2.

4. Rozin D.L. Tumors of the milk ducts. - 1989

5. Semiglazov V.F. and authors. Galactography in the early detection of breast cancer. // Questions of oncology, 1988, - t. 34, - No. 9.

Claims (1)

A method for the complex treatment of galactoforitis, including the use of antibiotics and anti-inflammatory drugs, characterized in that in addition, through the catheter, a treatment mixture is introduced directly into the affected duct, consisting of 1 part of dimexide, 2 parts of a 0.5% solution of novocaine and an antibiotic with high bacteriostatic activity and anti-inflammatory effect on the microflora of the secretion of the duct, a course of 1-2 times.