RU2198164C2 - N1-[2,2-диметил-1s-(пиридин-2-илкарбамоил)пропил]-n4-гидрок си-2r-изобутил-3s-метоксисукцинамид или его фармацевтически приемлемая соль, гидрат или сольват - Google Patents
N1-[2,2-диметил-1s-(пиридин-2-илкарбамоил)пропил]-n4-гидрок си-2r-изобутил-3s-метоксисукцинамид или его фармацевтически приемлемая соль, гидрат или сольват Download PDFInfo
- Publication number
- RU2198164C2 RU2198164C2 RU2000114634/04A RU2000114634A RU2198164C2 RU 2198164 C2 RU2198164 C2 RU 2198164C2 RU 2000114634/04 A RU2000114634/04 A RU 2000114634/04A RU 2000114634 A RU2000114634 A RU 2000114634A RU 2198164 C2 RU2198164 C2 RU 2198164C2
- Authority
- RU
- Russia
- Prior art keywords
- compound
- alkyl
- dimethyl
- isobutyl
- hydroxy
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Lubricants (AREA)
- Enzymes And Modification Thereof (AREA)
- Pyridine Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Saccharide Compounds (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/GB1997/003132 WO1999025693A1 (en) | 1997-11-13 | 1997-11-13 | Metalloproteinase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2000114634A RU2000114634A (ru) | 2002-07-10 |
| RU2198164C2 true RU2198164C2 (ru) | 2003-02-10 |
Family
ID=10807699
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2000114634/04A RU2198164C2 (ru) | 1997-11-13 | 1997-11-13 | N1-[2,2-диметил-1s-(пиридин-2-илкарбамоил)пропил]-n4-гидрок си-2r-изобутил-3s-метоксисукцинамид или его фармацевтически приемлемая соль, гидрат или сольват |
Country Status (21)
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20030701A1 (es) | 2001-12-20 | 2003-08-21 | Schering Corp | Compuestos para el tratamiento de trastornos inflamatorios |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1049651C (zh) * | 1994-01-20 | 2000-02-23 | 英国生物技术药物有限公司 | 金属蛋白酶抑制剂 |
| WO1997003966A1 (en) * | 1995-07-19 | 1997-02-06 | British Biotech Pharmaceuticals Limited | N-(amino acid) substituted succinic acid amide derivatives as metalloproteinase inhibitors |
-
1997
- 1997-11-13 CA CA002310593A patent/CA2310593C/en not_active Expired - Fee Related
- 1997-11-13 DE DE69720554T patent/DE69720554T2/de not_active Expired - Fee Related
- 1997-11-13 WO PCT/GB1997/003132 patent/WO1999025693A1/en not_active Application Discontinuation
- 1997-11-13 BR BR9714934-9A patent/BR9714934A/pt not_active Application Discontinuation
- 1997-11-13 GB GB9816317A patent/GB2333524A/en not_active Withdrawn
- 1997-11-13 RU RU2000114634/04A patent/RU2198164C2/ru not_active IP Right Cessation
- 1997-11-13 EP EP97912351A patent/EP1030842B1/en not_active Expired - Lifetime
- 1997-11-13 IL IL13521097A patent/IL135210A0/xx not_active IP Right Cessation
- 1997-11-13 KR KR10-2000-7004964A patent/KR100485479B1/ko not_active IP Right Cessation
- 1997-11-13 NZ NZ503642A patent/NZ503642A/en unknown
- 1997-11-13 ES ES97912351T patent/ES2195122T3/es not_active Expired - Lifetime
- 1997-11-13 HU HU0002811A patent/HUP0002811A3/hu unknown
- 1997-11-13 PT PT97912351T patent/PT1030842E/pt unknown
- 1997-11-13 TR TR2000/01353T patent/TR200001353T2/xx unknown
- 1997-11-13 AT AT97912351T patent/ATE236126T1/de not_active IP Right Cessation
- 1997-11-13 JP JP2000521077A patent/JP2001523666A/ja not_active Withdrawn
- 1997-11-13 DK DK97912351T patent/DK1030842T3/da active
- 1997-11-13 AU AU49584/97A patent/AU740420B2/en not_active Ceased
- 1997-11-13 PL PL97340494A patent/PL189542B1/pl not_active IP Right Cessation
- 1997-12-02 TW TW086118078A patent/TW474919B/zh not_active IP Right Cessation
-
2000
- 2000-05-12 NO NO20002480A patent/NO315702B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO315702B1 (no) | 2003-10-13 |
| ES2195122T3 (es) | 2003-12-01 |
| GB2333524A (en) | 1999-07-28 |
| DK1030842T3 (da) | 2003-07-28 |
| BR9714934A (pt) | 2000-10-03 |
| EP1030842B1 (en) | 2003-04-02 |
| CA2310593C (en) | 2007-05-08 |
| AU4958497A (en) | 1999-06-07 |
| NZ503642A (en) | 2001-10-26 |
| HUP0002811A2 (hu) | 2001-01-29 |
| PT1030842E (pt) | 2003-07-31 |
| ATE236126T1 (de) | 2003-04-15 |
| IL135210A0 (en) | 2001-05-20 |
| EP1030842A1 (en) | 2000-08-30 |
| NO20002480L (no) | 2000-05-12 |
| DE69720554D1 (de) | 2003-05-08 |
| JP2001523666A (ja) | 2001-11-27 |
| CA2310593A1 (en) | 1999-05-27 |
| KR100485479B1 (ko) | 2005-04-27 |
| TW474919B (en) | 2002-02-01 |
| KR20010031879A (ko) | 2001-04-16 |
| TR200001353T2 (tr) | 2000-10-23 |
| AU740420B2 (en) | 2001-11-01 |
| HUP0002811A3 (en) | 2002-11-28 |
| PL340494A1 (en) | 2001-02-12 |
| DE69720554T2 (de) | 2004-01-08 |
| PL189542B1 (pl) | 2005-08-31 |
| WO1999025693A1 (en) | 1999-05-27 |
| GB9816317D0 (en) | 1998-09-23 |
| NO20002480D0 (no) | 2000-05-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20071114 |