RU2197958C2 - Чистый 3r-3'r-стереоизомер зеаксантина для лечения дегенерации желтого пятна у людей - Google Patents

Чистый 3r-3'r-стереоизомер зеаксантина для лечения дегенерации желтого пятна у людей Download PDF

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Publication number
RU2197958C2
RU2197958C2 RU98110058/14A RU98110058A RU2197958C2 RU 2197958 C2 RU2197958 C2 RU 2197958C2 RU 98110058/14 A RU98110058/14 A RU 98110058/14A RU 98110058 A RU98110058 A RU 98110058A RU 2197958 C2 RU2197958 C2 RU 2197958C2
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RU
Russia
Prior art keywords
zeaxanthin
cells
stereoisomer
macular degeneration
carotenoids
Prior art date
Application number
RU98110058/14A
Other languages
English (en)
Russian (ru)
Other versions
RU98110058A (ru
Inventor
Кевин М. ГАРНЕТТ (US)
Кевин М. ГАРНЕТТ
Деннис Л. ГИРХАРТ (US)
Деннис Л. ГИРХАРТ
Луис Х. ГУЕРРА-САНТОС (US)
Луис Х. ГУЕРРА-САНТОС
Original Assignee
Зи Вижн Ллс
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/551,166 external-priority patent/US5854015A/en
Priority claimed from US08/551,153 external-priority patent/US5827652A/en
Application filed by Зи Вижн Ллс filed Critical Зи Вижн Ллс
Publication of RU98110058A publication Critical patent/RU98110058A/ru
Application granted granted Critical
Publication of RU2197958C2 publication Critical patent/RU2197958C2/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RU98110058/14A 1995-10-31 1996-10-30 Чистый 3r-3'r-стереоизомер зеаксантина для лечения дегенерации желтого пятна у людей RU2197958C2 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/551,153 1995-10-31
US08/551,166 US5854015A (en) 1995-10-31 1995-10-31 Method of making pure 3R-3'R stereoisomer of zeaxanthin for human ingestion
US08/551,166 1995-10-31
US08/551,153 US5827652A (en) 1995-10-31 1995-10-31 Zeaxanthin formulations for human ingestion

Publications (2)

Publication Number Publication Date
RU98110058A RU98110058A (ru) 2000-05-20
RU2197958C2 true RU2197958C2 (ru) 2003-02-10

Family

ID=27069666

Family Applications (1)

Application Number Title Priority Date Filing Date
RU98110058/14A RU2197958C2 (ru) 1995-10-31 1996-10-30 Чистый 3r-3'r-стереоизомер зеаксантина для лечения дегенерации желтого пятна у людей

Country Status (14)

Country Link
JP (1) JPH10512594A (xx)
KR (1) KR100570251B1 (xx)
CN (1) CN1104235C (xx)
AR (1) AR004245A1 (xx)
AU (1) AU710634B2 (xx)
BR (1) BR9611488A (xx)
CZ (1) CZ297575B6 (xx)
FI (1) FI980947A (xx)
HU (1) HU223208B1 (xx)
NO (1) NO981698L (xx)
PL (1) PL185465B1 (xx)
RU (1) RU2197958C2 (xx)
WO (1) WO1997016175A1 (xx)
ZA (1) ZA969139B (xx)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2446792C2 (ru) * 2005-01-21 2012-04-10 Промар Ас Солнцезащитные композиции, содержащие каротиноиды

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8088363B2 (en) * 2002-10-28 2012-01-03 Zeavision Llc Protection against sunburn and skin problems with orally-ingested high-dosage zeaxanthin
US8592662B2 (en) 2005-02-11 2013-11-26 Kalamazoo Holdings, Inc. Capsicum variety exhibiting a hyper-accumulation of zeaxanthin and products derived therefrom
JP2008532492A (ja) * 2005-02-11 2008-08-21 カラマズー・ホールディングス・インコーポレイテッド ゼアキサンチンの過剰蓄積を示すトウガラシ属品種およびそこから得られる産物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US308759A (en) * 1884-12-02 Curling hat-brims and machine therefor
ATE153700T1 (de) * 1989-08-30 1997-06-15 Applied Food Biotech Inc Verfahren zur herstellung einer zeaxanthin enthaltenden zusammensetzung mittels eines mikroorganismus der spezies flavobacterium multivorum
US5310764A (en) * 1992-05-08 1994-05-10 Steven Baranowitz Treatment of age related macular degeneration with beta-carotene

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
МОРОЗОВ В.И. и др. Фармакотерапия глазных болезней. - М.: Медицина, 1989, с.156-158. *
Реферат из АБД Medline: Seddon -JM et al. Dietary carotenoids, vitamins A,C, and E, and advanced age-related macular degeneration. Eye Disease Case-Control Group. JAMA 1994, Nov. 9; 272(8); 1413-20. *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2446792C2 (ru) * 2005-01-21 2012-04-10 Промар Ас Солнцезащитные композиции, содержащие каротиноиды

Also Published As

Publication number Publication date
JPH10512594A (ja) 1998-12-02
FI980947A (fi) 1998-04-29
HUP9802314A3 (en) 1999-05-28
CN1201388A (zh) 1998-12-09
CN1104235C (zh) 2003-04-02
CZ297575B6 (cs) 2007-02-07
NO981698L (no) 1998-06-08
AU7050196A (en) 1997-05-08
KR100570251B1 (ko) 2006-06-21
AU710634B2 (en) 1999-09-23
NO981698D0 (no) 1998-04-16
WO1997016175A1 (en) 1997-05-09
KR19990067180A (ko) 1999-08-16
ZA969139B (en) 1997-09-25
MX9605248A (es) 1998-06-30
FI980947A0 (fi) 1996-10-30
PL185465B1 (pl) 2003-05-30
PL326558A1 (en) 1998-09-28
HU223208B1 (hu) 2004-03-29
AR004245A1 (es) 1998-11-04
HUP9802314A2 (hu) 1999-04-28
BR9611488A (pt) 1999-01-19
CZ130998A3 (cs) 1998-07-15

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20031031

NF4A Reinstatement of patent
MM4A The patent is invalid due to non-payment of fees

Effective date: 20151031