RU2193379C2 - Method for surgical treatment of dystrophic diseases in retina and optic nerve - Google Patents

Abstract

FIELD: medicine, ophthalmosurgery. SUBSTANCE: in projection above macular area one should form a pouch to implant a transplant made of a constant magnetic material with its own constant magnetic field with alternating magnetic poles at transplant's surface, then comes the impact of external constant magnetic field onto a transplant on the 3d day after operation. There are not less than two alternating magnetic poles. External impact of constant magnetic field is carried out once/3 mo. EFFECT: higher efficiency of therapy. 2 cl

Description

 The invention relates to medicine, in particular to ophthalmology, and is intended to enhance vasuclarization, activation of blood supply in the vessels of the retina, choroid and stabilization of visual functions in the surgical treatment of degenerative diseases of the retina and optic nerve.

 A known method of treating “dry” involutional chorioretinal macular degeneration, including the formation of a tunnel at the posterior pole in the projection above the macular region, into which a xenograft from cattle pericardium was implanted (see Cheglakov Yu.A. et al. Xenografts for treating patients with “dry” involutional chorioretinal macular degeneration. Ophthalmosurgery, 1996, 2, pp. 14-18).

 The disadvantage of this method is the short-term therapeutic effect, because the implantation of various grafts to the posterior pole of the eye does not always lead to a positive result and stabilization of eye functions.

 The objective of the invention is the development of a surgical method for the treatment of degenerative diseases of the retina and optic nerve.

 The technical result is achieved by the fact that in the method of surgical treatment of degenerative diseases of the retina and optic nerve, including implantation of the graft to the posterior pole of the eyeball, a distinctive feature of which is that in the projection above the macular region, a pocket is formed into which a graft of polymer permanent magnetic material is implanted. having its own constant magnetic field with alternating magnetic poles on the surface of the graft, followed by Twi to the transplant of an external constant magnetic field on the third day after the operation. Moreover, the number of alternating magnetic poles on the surface of the graft is selected more than two. In this case, the external influence of a constant magnetic field is carried out once every three months.

 The method is as follows.

 Processing of the surgical field and anesthesia is carried out according to the generally accepted technique. In the lower outer quadrant of the eyeball, 10 mm from the limb, an incision of the conjunctiva and tenon membrane is performed, 5-7 mm long. Using a special spatula at the posterior pole of the eyeball, a pocket is formed into which a graft of polymer permanent magnetic material is implanted, which has its own permanent magnetic field with a strength of 1-4 mT. The transplant is made with alternating magnetic poles on its surface, the number of which is selected more than two. The operation is completed by applying a nodal suture to the conjunctiva and then a monocular dressing. Under the conjunctiva, an injection of dexazone with an antibiotic is given.

 On the third day after the operation and for ten days, the transplant is exposed to an external constant magnetic field with a strength of 0.05 - 0.09 T. The procedure is repeated and in the long term after the operation, once every three months. Subsequently, the graft is removed from the eye.

 The method is illustrated by clinical examples.

 Example 1. Patient E. Diagnosis: "Dry" involutional chorioretinal macular degeneration OD. Before surgery, the visual acuity of OD is 0.1 n / k. Foveolar sensitivity 21 dB. OCK in the orbital artery 5.6 ml / min.

 Operation progress: treatment of the surgical field and anesthesia were performed according to the generally accepted technique. In the lower outer quadrant of the eyeball, 10 mm from the limb, an incision of the conjunctiva and tenon membrane was performed with a length of 5-7 mm. Using a special spatula, a pocket was formed at the posterior pole of the eyeball into which a graft of polymer permanent magnetic material containing 35 wt% barium ferrite and having its own constant magnetic field with a strength of 4 mT was implanted. The transplant with a diameter of 10 mm and a thickness of 0.5 mm is made with alternating magnetic poles on its surface, the number of which is chosen equal to two. The operation was completed by applying a nodal suture to the conjunctiva and then a monocular dressing. Under the conjunctiva, they injected dexazone with an antibiotic.

 On the third day after the operation and for ten days, an external constant magnetic field with an intensity of 0.09 T was exposed to the transplant. The procedure was repeated once three months after surgery, followed by removal of the graft from the eye.

 During the control examination one year after the operation, visual acuity of OD is 0.4 n / a. Foveolar sensitivity 28 dB. OCK in the orbital artery 6.6 ml / min.

 Example 2. Patient C. Diagnosis: "Dry" involutional chorioretinal macular degeneration OS. Before surgery, the visual acuity of the OS is 0.05 n / a. Foveolar sensitivity 17 dB. OCK in the orbital artery 5.5 ml / min.

 Operation progress: treatment of the surgical field and anesthesia were performed according to the generally accepted technique. In the lower outer quadrant of the eyeball, 10 mm from the limb, an incision of the conjunctiva and tenon membrane was performed with a length of 5-7 mm. Using a special spatula, a pocket was formed at the posterior pole of the eyeball into which a graft of polymer permanent magnetic material containing 15 wt% strontium ferrite and having its own constant magnetic field with a strength of 1 mT was implanted. The transplant with a diameter of 10 mm and a thickness of 0.5 mm is made with alternating magnetic poles on its surface, the number of which is chosen equal to two. The operation was completed by applying a nodal suture to the conjunctiva and then a monocular dressing. Under the conjunctiva, they injected dexazone with an antibiotic.

 On the third day after the operation and for ten days, an external constant magnetic field with an intensity of 0.05 T was exposed to the transplant. The procedure was repeated twice every three months after surgery, followed by removal of the graft from the eye.

 During the control examination one year after the operation, the visual acuity of the OS is 0.2 n / k. Foveolar sensitivity 22 dB. OCK in the orbital artery 6.0 ml / min.

 The proposed method allows to increase blood supply in the vessels of the retina, choroid and stabilize visual functions.

Claims (3)

 1. A method for the surgical treatment of degenerative diseases of the retina and optic nerve, including implantation of the graft to the posterior pole of the eyeball, characterized in that a pocket is formed in the projection above the macular region into which the graft is implanted from a polymer permanent magnetic material having its own constant magnetic field with alternating on the surface of the graft with magnetic poles, followed by exposure to the transplant of an external constant magnetic field on the third day After surgery.  2. The method according to p. 1, characterized in that the number of magnetic poles alternating on the surface of the graft is selected at least two.  3. The method according to p. 1, characterized in that the external influence of a constant magnetic field is carried out once every three months.