RU2190419C1 - Medicinal vegetable species "fitomaks" - Google Patents

Abstract

FIELD: medicine, particularly, production of medicinal preparations of natural origin possessing immunostimulating action. SUBSTANCE: medicinal vegetable species contains St. Johnswort herb, linden flowers, marigold flowers, way-grass herb, wild rosemary, mint herb, plantain leaves, field horsetail herb, tansy flower clusters, licorice roots, dog rose fruits. According to the invention, species additionally includes mallow roots, immortelle flowers, hawthorn fruits, valerian roots, bistort roots, inula roots, sweetclover herb, maize stigmas, deadly nightshade herb, bog gnaphalium herb, wild pansy flowers, bur beggarticks herb, celandine herb, and sage leaves taken in determined ratio. The species is applied at rehabilitation after serious sickness, at immunodeficient conditions, and also for oncologic patients after chemo-radiation therapy for correction of disturbed functions of an organism. EFFECT: antiinflammatory, spasmolytic, reparative and sedative action.

Description

 The invention relates to medicine, namely to phytotherapeutic agents for treating patients with a weakened immune system and concomitant diseases of the digestive tract and upper respiratory tract, used alone, as well as in combination with antibacterial, anti-inflammatory, antispasmodic, non-specific immunocorrection therapy and physiotherapy.

 The invention relates to a medicinal plant collection with simultaneous immunostimulating, anti-inflammatory, choleretic action, as well as antispasmodic, reparative, analgesic, sedative activity.

 Known medicinal herbal collection, having both an immunostimulating and choleretic effect (see RF patent 2129433, publ. 20.10.97, Mkl.6 A 61 K 35/78, "Medicinal substance").

 The well-known drug collection contains: Manchurian aralia (roots), St. John's wort perforated (ground part), large plantain (leaves), dioecious nettle (ground part), medicinal calendula (flowers), tansy (flowers) in a ratio of 25:25:20: 10:10:10 (%) in the collection, respectively.

 The applied plant collection has a general strengthening, choleretic effect, but it is not possible to achieve a pronounced anti-inflammatory, antispasmodic, and sedative effect due to the absence of plants with a high antimicrobial effect in the phytocomposition.

 A medicinal substance is known that has a general strengthening, anti-inflammatory, analgesic, choleretic, pressure normalizing, sedative, cardiotonic, expectorant effect (see ext. Application 93015143, publ. 20.03.97, Mkl.6 C 12 G 3/00, "Composition ingredients for the Volgo-Don balm).

 The known medicinal substance contains calamus, barberry, mint, St. John's wort, oregano, oak, thyme, sage, eucalyptus, linden, calendula, raspberries, currants, blueberries, lingonberries, wormwood, licorice, bird cherry, hops, elecampane, pine buds, rose hips, mother and stepmother, clover, tansy.

 The applied drug substance does not allow to achieve a pronounced antioxidant, immunomodulating effect, as well as to increase the adaptive ability of a person to external adverse effects.

 Closest to the proposed solution is a medicinal herbal collection with antiviral, antimicrobial and immunomodulating effects, selected as a prototype (see RF patent 2160596, publ. 20.12.2000, Mcl 6 A 61 K 35/78, "Collection of medicinal products plants with antiviral, antimicrobial and immunomodulatory effects ").

Selected as a prototype medicinal plant collection contains the following components, wt.%:
St. John's wort grass - 7.0-9.0
Nettle grass - 7.0-9.0
Linden flowers - 7.0-9.0
Calendula flowers - 7.0-9.0
Pharmacy chamomile flowers - 7.0-9.0
Highlander's grass - 7.0-9.0
Ledum grass - 2.0-4.0
Coltsfoot leaves - 2.0-4.0
Peppermint Herb - 2.0-4.0
Plantain Leaves - 2.0-4.0
Pine buds - 2.0-4.0
Yarrow herb - 2.0-4.0
Fennel - 2.0-4.0
Horsetail grass - 2.0-4.0
Inflorescences of tansy - 1.5-3.0
Licorice roots - 1.5-3.0
Oregano grass - 7.0-9.0
Rose Hips - Else
One of the leading trends in the development of modern medicine is the use of herbal medicine, which allows creating a comprehensive treatment for patients with a weakened immune system and concomitant diseases of the digestive tract and upper respiratory tract.

 The disadvantage of the known medicinal plant collection, selected as a prototype, is not a complex effect on patients with a weakened immune system and concomitant diseases of the digestive tract and upper respiratory tract antioxidant, immunostimulating, anti-inflammatory, antispasmodic, hepatoprotective and choleretic actions.

 The objective of the present invention is to expand the arsenal of prophylactic and therapeutic agents based on plants, used in rehabilitation after a serious illness, in immunodeficiency states, as well as for cancer patients after chemo and radiation therapy to correct impaired body functions by creating a plant collection with antioxidant, immunostimulating, anti-inflammatory antispasmodic, hepatoprotective and choleretic properties.

The solution to this problem is achieved by the fact that the proposed medicinal herbal collection "FITOMAX", including St. John's wort grass, linden flowers, calendula flowers, bird highlander grass, marsh rosemary, mint grass, plantain leaves, horsetail grass, tansy inflorescences, licorice roots, licorice fruits , according to the invention, additionally contains marshmallow roots, immortelle flowers, hawthorn fruits, valerian roots, snake highlander roots, elecampane roots, sweet clover grass, corn stigmas, black nightshade grass, marshy grass, flowers f three-colored alki, grass of a series of three-parted, celandine grass, sage leaves in the following ratio of components, parts by weight:
Althea roots - 2-10
Ledum shoots - 1-2
Helichrysum flowers - 1-10
Hawthorn fruits - 1-10
Valerian Roots - 2-10
The roots of the Highlander snake - 1-10
Highlander's Grass - 4-12
Elecampane Roots - 1-4
Melilot grass - 1-10
St. John's wort grass - 1-10
Calendula flowers - 4-30
Corn stigmas - 1-6
Linden flowers - 1-10
Peppermint Herb - 1-4
Black nightshade grass - 1-6
Tansy inflorescences - 1-2
Plantain Leaves - 1-4
Licorice roots - 4-40
Marshmallow grass - 4-20
Tricolor violet flowers - 1-2
Field Horsetail Grass - 1-4
Grass of a series of three-parted - 6-80
Large celandine grass - 5-40
Sage Leaves - 1-10
Rose hips - 1-10
The ingredients used are widely used in herbal medicine.

 The proposed ratio of medicinal plants included in the collection is selected empirically and represents the most appropriate quantitative combination of ingredients.

 The proposed collection contains all the necessary substances, the complex use of which has an effective effect on the body of patients with a weakened immune system and concomitant diseases of the digestive tract and upper respiratory tract, during the rehabilitation of patients after a serious illness, as well as for cancer patients after chemo and radiation therapy for correction impaired body functions.

 The inventive collection has both antioxidant properties, stimulates the functions of the immune system, exhibits antispasmodic and anti-inflammatory effects, increases the ability of a person to adapt to external adverse effects, exhibits hepatoprotective and choleretic effects.

 New features in the invention are the creation of a composition containing, along with St. John's wort, linden flowers, calendula flowers, bird highlander grass, marsh rosemary, mint grass, plantain leaves, horsetail grass, tansy inflorescences, licorice roots, rose hips, and also roots marshmallow, immortelle flowers, hawthorn fruits, valerian roots, snake highlander roots, elecampane roots, sweet clover grass, corn stigmas, black nightshade grass, moss dried grass, three-color violet flowers, three times a row grass tionary, celandine herbs, sage leaves.

 The relationship of new features with new technical results is explained below.

 The inclusion of marshmallow roots in the composition provides good emollient, enveloping, anti-inflammatory and analgesic properties. Althea roots contain pectin, starch, sucrose, fatty oil. The infusion of the drug collection, which contains, along with other ingredients, the marshmallow roots, relieves inflammation of the mucous membrane of the respiratory tract, coughs, cures bronchitis, inflammatory processes of the intestines, and relieves inflammation in dyspepsia, kidney diseases, gastric ulcer and duodenal ulcer.

 The presence of shoots of Ledum marsh has an antitussive, expectorant, bronchodilator, anti-inflammatory, bactericidal, antiallergic and diaphoretic effect, expands the trace element.

 The inclusion in the composition of the flowers of sandy immortelle, containing essential oil, flavonoids, tannins, resins, sterols, saponins, dyes, fatty acids, vitamins K and C, provides a choleretic effect for liver diseases, inflammation of the bladder, diseases of the gastrointestinal tract .

 The inclusion in the composition of the composition of the fruit of hawthorn blood-red, containing organic acids, flavonoids glycosides, choline, acetylcholine, pigment carotene, tannins, gives the composition a restorative, adaptogenic properties in functional disorders of cardiac activity, atrial fibrillation, angina pectoris, relieves headache, dizziness lowers blood pressure.

 The roots of valerian officinalis, containing essential valerian oil, organic acids, alkaloids valerin and hatinin, glycosides, tannins, have a calming effect on the central nervous system, relieve spasms, dilate the blood vessels of the heart, and lower blood pressure.

 The inclusion of snake snake roots in the composition containing tannins, phlobafen, vitamins K and C, flavanoid glycosides, organic acids, and essential oil provide hemostatic, analgesic, and anti-inflammatory properties of the composition that enhance the activity of the heart and narrow blood vessels.

 The grass of the mountaineer avian increases immunity, has antimicrobial, detoxification, volatile, anti-inflammatory and antiseptic, diuretic and anti-toxic, antipyretic and hemostatic effects. It is rich in vitamins and minerals.

 The roots of elecampane give the composition a general strengthening effect, which consists in improving appetite, digestion, especially with low acidity, and increase diuretic, diaphoretic, expectorant, anti-inflammatory and soothing effect. They contain vitamins K, saponins, resins, essential oil.

 Melilotus officinalis herb has a calming effect, gives the composition wound healing, emollient, analgesic properties, relieves inflammation in chronic bronchitis, insomnia, migraines and, while being a corrective agent, enhances the regenerative effect after diseases. It contains coumarin, dicumarin, which prevents blood coagulation.

 St. John's wort grass normalizes the functions of the gastrointestinal tract, gives the composition antispasmodic, vasodilator, blood circulation stimulating and diuresis properties. The presence of St. John's wort grass in the composition promotes digestion, strengthens capillaries, destroys microbes, improves the regeneration of damaged tissues.

 Calendula officinalis flowers enhance the anti-inflammatory, bactericidal, cardiotonic, sedative effect of the composition. At the same time enhancing the metabolic function of the liver, they stimulate bile formation, act as an anesthetic and immunomodulating agent.

 Corn stigmas enhance the blood-clotting properties of the composition and, at the same time, its choleretic effect, stimulate bile formation.

 Heart-shaped linden flowers normalize the function of the bronchopulmonary system, stimulate sweating and diuresis, calm the nervous system, and increase the formation of gastric juice and bile.

 Peppermint grass gives the composition simultaneously choleretic, antitoxic, antiseptic, anesthetic, antispasmodic, sedative, vasodilating, analgesic.

 Black nightshade grass is a stimulant for adrenal function and gives the composition a hormone-correcting effect on the endocrine glands.

 Inflorescences of tansy along with choleretic and antiseptic properties stimulate the release of gastric juice with high acidity, act antitoxic, antimicrobial.

 The leaves of the large plantain normalize the enzymatic composition of the stomach, have secretolytic, anti-inflammatory, wound healing, hemostatic, bactericidal, diuretic, anti-allergic effects. They have the ability to increase blood hemoglobin, indirectly being an immunocorrector.

 Licorice roots increase the body's adaptive ability to harmful factors, have an immunomodulatory effect on the body, are an antiseptic, increase the production of hormones in the adrenal cortex, and regulate the water-salt balance of the body. In addition, licorice root preparations lower the temperature, promote sputum discharge, and increase perspiration.

 Sushitsa grass is a swampy blood pressure corrector, an anti-inflammatory, astringent, antibacterial agent that simultaneously enhances intestinal motility, blood coagulation, and restoration of wound surfaces.

 The inclusion of tricolor violet flowers in the composition provides a simultaneous antispasmodic, anti-inflammatory effect, enhances the secretion of bronchial glands, dilutes sputum, promotes expectoration, excretion of urine and sweat.

 The horsetail grass has diuretic, antitoxic, hemostatic and anti-inflammatory properties, contains a large number of silicates that contribute to the proliferation of body tissues, and corrects the functions of the male genital area.

 The grass of the tripartite series is an anti-inflammatory, diaphoretic, diuretic, vitamin remedy for lung diseases, ulcerative colitis, improves digestion, normalizes impaired metabolism in skin diseases.

 The grass of the large celandine has antioxidant properties, inhibits the growth of some malignant tumors, reduces and soothes pain, stops cramps and cramps.

 Sage leaves enhance the soothing, astringent, anti-inflammatory, antimicrobial effect of the composition, and reduce sweat secretion.

 Rose hips enhance the functions of the immune system and give the composition immunomodulating properties, and as a vitamin, vasodilator, antimicrobial agent, including a wide range of organic compounds and trace elements, they activate enzyme systems and increase the body's resistance to adverse factors.

 The claimed medicinal herbal collection "FITOMAX" passed a six-year test in the medical company "Fiteks" in Chelyabinsk and a two-year check in the Chelyabinsk Regional Oncology Center, showed high efficiency in the process of rehabilitation after severe diseases of cancer patients after chemo-and radiation therapy, patients with weakened immune system and concomitant diseases of the digestive tract and upper respiratory tract, for example, patients diagnosed with bronchitis, patients with acute and chronic abolevaniyami lungs and immunocompromised patients with diseases of the gastrointestinal tract and immune deficiency.

 The studies revealed the antioxidant effect of the claimed collection on patients, its immunomodulating properties, anti-inflammatory, bronchodilator, hepatoprotective and choleretic, as well as corrective effects on the functions of the male and female genitalia.

 The inventive medicinal herbal collection "FITOMAX" has a novelty and inventive step, since when searching the sources of patent and scientific and technical documentation, the applicant did not reveal any well-known technical solutions that would describe an identical collection of medicinal plants.

 The inventive collection can be successfully applied in medicine and repeatedly reproduced, therefore, it meets the criterion of "industrial applicability".

 Since the claimed FITOMAX collection provides a wide range of treatable acute and chronic diseases, including acute respiratory diseases, immunodeficiency, diseases of the gastrointestinal tract, rehabilitation after serious illnesses, after chemo-radiation therapy to correct impaired body functions, it meets the criterion " positive effect".

The proposed FITOMAX collection is prepared as follows:
6 teaspoons (40 grams) of the collection pour 500 ml of 40% alcohol, insist for two weeks and filter. Take 0.5-1 teaspoon 2-3 times a day for 1-2-3 months.

An example of a medicinal plant collection "FITOMAX". Composed a composition comprising the following substances, g:
Althea Roots - 15
Ledum shoots - 5
Immortelle Flowers - 15
Hawthorn fruit - 35
Valerian Roots - 40
Roots of the Highlander Snake - 25
Highlander's Grass - 40
Elecampane Roots - 15
Sweet clover grass - 25
St. John's Wort Grass - 35
Calendula flowers - 20
Corn stigmas - 15
Linden flowers - 25
5 mint grass
Black nightshade grass - 25
Tansy inflorescences - 5
Plantain Leaves - 15
Licorice roots - 50
Mushroom sushnitsa grass - 20
Tri-color violet flowers - 5
Horsetail grass - 5
Grass of a series of three-parted - 60
Celandine grass large - 125
Sage Leaves - 45
Rosehips - 25
Over the years of verification of the claimed plant collection "FITOMAX" hundreds of patients used it.

Patient M., 50 years old. The diagnosis of frequent acute respiratory infections (acute respiratory infections). Sick 5 years. Complaints of frequent colds - 7-8 times a year with a mandatory increase in temperature to 37.5 ^o C, sometimes dry cough.

 Several times a year, he underwent inpatient treatment, where he received courses of antibiotic therapy and immunotherapy. It became better, but after discharge everything was repeated: the temperature rose, a painful cough appeared. Then he took antibiotic therapy courses on an outpatient basis.

 The district doctor proposed to undergo a course of treatment with the FITOMAX drug collection for 3 months. After the second month of treatment with the FITOMAX drug collection, the number of acute exacerbation of acute respiratory infections decreased to 1-2 times a year. In this case, the cold passed quickly, without fever. The patient stopped being treated permanently. It is recommended that the patient repeat the course of treatment with the FITOMAX drug collection.

Patient L., 18 years old. The diagnosis is immunodeficiency. Sick for 3 years. Complaints about a periodic increase in temperature to 37.5 ^o C (6-9 times a year) and a decrease in blood leukocytes to 3-3.5 thousand (with a norm of 6-8 thousand). He repeatedly underwent inpatient and outpatient courses of antibiotic therapy and immunotherapy, was treated by bees. It didn’t get any better. The district doctor proposed to undergo a course of treatment with the FITOMAX drug collection for 3 months. As a result of treatment with the FITOMAX drug collection within 3 months, the temperature became 36.6 ^o C, the leukocytes practically became normal - 5.9 thousand. It was recommended to repeat the treatment with the FITOMAX drug collection for another 1.5 years with 3-month courses.

 Patient S., 65 years old. The diagnosis is breast cancer. Sick 1 year. She underwent 3 courses of radiation therapy, surgical treatment, and then another 6 courses of chemotherapy. The forecast is favorable for the next 5 years. However, the patient complained of weakness, nausea, poor appetite and mood. The oncologist recommended a course of treatment with the FITOMAX drug collection to normalize the gastrointestinal tract and immunity, as well as to improve overall well-being.

 The patient took "FITOMAX" for 3 months. As a result of treatment with the FITOMAX drug collection, the blood leukocytes returned to 7 thousand, the unpleasant symptoms of nausea and weakness disappeared, and the mood improved. After a year, the patient is recommended to repeat the course of treatment with phyto-collection.

Claims (1)

Medicinal plant collection with an immunostimulating effect, including St. John's wort, linden flowers, calendula flowers, bird of highlander, Ledum, mint grass, plantain leaves, horsetail grass, tansy inflorescences, licorice roots, rose hips, additionally containing marshmallow roots, immortelle flowers, hawthorn fruits, valerian roots, snake highlander roots, elecampane roots, sweet clover grass, corn stigmas, black nightshade grass, moss dried grass, tricolor violet flowers, grass of a series of three hrazdelnoy, celandine herbs, sage leaves in the following ratio, mass parts .:
Althea roots - 2-10
Ledum shoots - 1-2
Helichrysum flowers - 1-10
Hawthorn fruits - 1-10
Valerian Roots - 2-10
The roots of the Highlander snake - 1-10
Highlander's Grass - 4-12
Elecampane Roots - 1-4
Melilot grass - 1-10
St. John's wort grass - 1-10
Calendula flowers - 4-30
Corn stigmas - 1-6
Linden flowers - 1-10
Peppermint Herb - 1-4
Black nightshade grass - 1-6
Tansy inflorescences - 1-2
Plantain Leaves - 1-4
Licorice roots - 4-40
Marshmallow grass - 4-20
Tricolor violet flowers - 1-2
Field Horsetail Grass - 1-4
Grass of a series of three-parted - 6-80
Large celandine grass - 5-40
Sage Leaves - 1-10
Rose hips - 1-10