RU2170079C2 - Антимикробная композиция для перорального применения и предотвращения образования зубного налета и соединение - Google Patents

Антимикробная композиция для перорального применения и предотвращения образования зубного налета и соединение Download PDF

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Publication number
RU2170079C2
RU2170079C2 RU98107654/14A RU98107654A RU2170079C2 RU 2170079 C2 RU2170079 C2 RU 2170079C2 RU 98107654/14 A RU98107654/14 A RU 98107654/14A RU 98107654 A RU98107654 A RU 98107654A RU 2170079 C2 RU2170079 C2 RU 2170079C2
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RU
Russia
Prior art keywords
tert
butyl
alkyl
compound
activity
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RU98107654/14A
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English (en)
Russian (ru)
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RU98107654A (ru
Inventor
Орум Д. СТРИНГЕР (US)
Орум Д. СТРИНГЕР
Джон К. БРАМС (US)
Джон К. БРАМС
Малати СУБРАМАНИАН (US)
Малати СУБРАМАНИАН
Эрнст Э. КЕЛЛИ (US)
Эрнст Э. КЕЛЛИ
Original Assignee
Колгейт-Палмолив Компани
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Publication of RU98107654A publication Critical patent/RU98107654A/ru
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/347—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
    • C07C39/14—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings with at least one hydroxy group on a condensed ring system containing two rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
    • C07C39/15—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings with all hydroxy groups on non-condensed rings, e.g. phenylphenol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
    • C07C39/17—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings containing other rings in addition to the six-membered aromatic rings, e.g. cyclohexylphenol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/26—Phenanthrenes; Hydrogenated phenanthrenes

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
RU98107654/14A 1995-09-22 1996-09-18 Антимикробная композиция для перорального применения и предотвращения образования зубного налета и соединение RU2170079C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US419695P 1995-09-22 1995-09-22
US60/004,196 1995-09-22

Publications (2)

Publication Number Publication Date
RU98107654A RU98107654A (ru) 2000-02-27
RU2170079C2 true RU2170079C2 (ru) 2001-07-10

Family

ID=21709632

Family Applications (1)

Application Number Title Priority Date Filing Date
RU98107654/14A RU2170079C2 (ru) 1995-09-22 1996-09-18 Антимикробная композиция для перорального применения и предотвращения образования зубного налета и соединение

Country Status (12)

Country Link
US (1) US5723500A (enExample)
EP (1) EP0852486A2 (enExample)
JP (1) JPH11511473A (enExample)
CN (1) CN1088579C (enExample)
AU (1) AU708974B2 (enExample)
BR (1) BR9610562A (enExample)
CA (1) CA2232838A1 (enExample)
CO (1) CO4770945A1 (enExample)
MX (1) MX9802188A (enExample)
RU (1) RU2170079C2 (enExample)
WO (1) WO1997010800A2 (enExample)
ZA (1) ZA967841B (enExample)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2289392C2 (ru) * 2002-05-10 2006-12-20 Колгейт-Палмолив Компани Антибактериальное средство для чистки зубов со свойствами против зубного налета и для освежения дыхания
RU2309929C2 (ru) * 2005-11-15 2007-11-10 Институт Молекулярной Генетики Российской Академии Наук (Имг Ран) Высокомеченный тритием хлорогексидин
RU2414209C2 (ru) * 2006-05-01 2011-03-20 Колгейт-Палмолив Компани Композиция с силиконовым композитом для ухода за полостью рта
RU2429884C1 (ru) * 2010-06-28 2011-09-27 Общество С Ограниченной Ответственностью "Акцент" Композиция для получения антисептического средства (варианты) и способ ее применения
RU2505798C2 (ru) * 2008-04-04 2014-01-27 Колгейт-Палмолив Компани Анализ субстратов, на которые нанесены агенты
RU2509553C2 (ru) * 2009-06-03 2014-03-20 Колгейт-Палмолив Компани Композиции на основе бориновой кислоты

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TR199801528T2 (xx) * 1996-02-08 1998-11-23 Warner-Lambert Company Y�ksek derecede ��z�n�r pirofosfat i�eren, di� ta��na kar�� etkili di� temizli�i bile�imi.
US5851513A (en) * 1998-02-03 1998-12-22 Colgate Palmolive Company Antiplaque oral composition and method
US5998487A (en) * 1998-04-08 1999-12-07 Colgate-Palmolive Company Anti-inflammatory and antibacterial benzyl phenol agents and their use in oral compositions
US6113884A (en) * 1998-11-13 2000-09-05 Colgate-Palmolive Company Mixed surfactant, high foaming dentifrice exhibiting enhanced antibacterial compound uptake on dental tissue
US6403652B1 (en) * 2000-06-30 2002-06-11 Colgate-Palmolive Company Method and composition
US6753451B2 (en) * 2000-08-28 2004-06-22 Ciba Specialty Chemicals Corporation Process for the preparation of phenylphenol compounds
AU2002223966A1 (en) 2000-12-20 2002-07-01 Warner Lambert Company Non-halogenated naphthol compounds and antimicrobial compositions containing the same
WO2002050002A1 (en) * 2000-12-20 2002-06-27 Warner-Lambert Company Llc Non-halogenated phenyl substituted phenols, antimicrobial compositions containing the same, and methods of using the same
US20030207945A1 (en) * 2001-12-20 2003-11-06 Harper David Scott Non-halogenated phenyl substituted phenols, antimicrobial compositions containing the same, and methods of using the same
AU2002223958A1 (en) 2000-12-20 2002-07-01 Warner-Lambert Company Llc Non-halogenated phenoxy and/or benzyloxy phenols and antimicrobial compositions containing them
AU2002347508A1 (en) * 2001-12-20 2003-07-09 Warner-Lambert Company Llc Non-halogenated hydroxyalkyl-substituted phenol compounds, antimicrobial compositions containing the same, and methods of using the same
US20050255054A1 (en) * 2004-04-30 2005-11-17 Philp Graham K Jr Method for tooth whitening, in particular a system for tooth whitening using a dissolvable tray or strip
EP1776083A4 (en) * 2004-07-02 2010-06-02 Discus Dental Llc SENSITIVITY-RELATED TOOTH COMPOSITIONS
US20060140881A1 (en) * 2004-12-22 2006-06-29 Guofeng Xu Oral care compositions containing flavonoids and flavans
US8895084B2 (en) 2004-12-23 2014-11-25 Colgate-Palmolive Company Oral care composition containing extract of unoxidized Camellia
US20060141039A1 (en) * 2004-12-23 2006-06-29 Colgate-Palmolive Company Oral compositions containing oxidized camellia
US8119169B2 (en) * 2004-12-28 2012-02-21 Colgate-Palmolive Company Oregano oral care compositions and methods of use thereof
US8071077B2 (en) 2004-12-29 2011-12-06 Colgate-Palmolive Company Oral compositions containing biphenol antibacterial compounds
US20060140883A1 (en) * 2004-12-29 2006-06-29 Colgate-Palmolive Company Oral care compositions containing a eucalyptus extract
US8425881B2 (en) 2005-03-18 2013-04-23 Colgate-Palmolive Company Antibacterial 3′,5-disubstituted 2,4′-dihydroxybiphenyl compounds, derivatives and related methods
BRPI0608631A2 (pt) 2005-03-18 2010-11-30 Colgate Palmolive Co composição oral antiplaca, pasta de dentes ou composição em gel, e, método para inibir crescimento bacteriano na cavidade oral de um animal
US20070190090A1 (en) * 2006-02-07 2007-08-16 Whitehill Oral Technologies, Inc. Sialagogue based oral care products
US9649513B2 (en) * 2006-03-24 2017-05-16 Colgate—Palmolive Company Aerosol dispenser
US9682256B2 (en) * 2006-07-14 2017-06-20 Colgate-Palmolive Company Methods of making compositions comprising films
CN102781898B (zh) * 2009-11-05 2014-12-24 菲布他丁有限合伙公司 使用q2拟肽的gpbp抑制
CN104411287A (zh) 2012-06-29 2015-03-11 高露洁-棕榄公司 包含微晶纤维素和羧甲基纤维素的高水含量口腔组合物
US20200375949A1 (en) * 2017-11-22 2020-12-03 The Trustees Of The University Of Pennsylvania Bisphenol compounds

Citations (4)

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FR2646601A1 (fr) * 1989-05-08 1990-11-09 Beecham Inc Dentifrice et compositions orales utiles pour inhiber les calculs dentaires
US5043154A (en) * 1987-01-30 1991-08-27 Colgate-Palmolive Co. Antibacterial, antiplaque, anticalculus oral composition
WO1992000721A1 (en) * 1990-07-13 1992-01-23 The Procter & Gamble Company Anticalculus/antiplaque compositions using azacycloalkane diphosphonates
EP0492998A1 (en) * 1990-12-20 1992-07-01 Colgate-Palmolive Company Anticalculus oral compositions

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CH558342A (de) * 1968-08-28 1975-01-31 Sandoz Ag Verfahren zur herstellung von neuen phenolderivaten.
US3800051A (en) * 1970-09-21 1974-03-26 Dow Chemical Co Reducing serum cholesterol with certain substituted phenols
FR2128026A1 (en) * 1971-03-01 1972-10-20 Soredev 3,4-dimethyl-6-(2,4,4-trimethylpent-2-yl) phenol - with antibacterial activity, prepn
FR2165741A1 (en) * 1971-12-28 1973-08-10 Etu Therapeutique Bureau Cyclopent(en)yl-dialyl-phenols - with bactericidal/bacteriostatic and fungicidal/fungistatic activity
US4321257A (en) * 1974-07-08 1982-03-23 Johnson & Johnson Potentiated medicaments
JPS5929161B2 (ja) * 1978-12-05 1984-07-18 味の素株式会社 揮発性防菌防黴製剤
US5188821A (en) * 1987-01-30 1993-02-23 Colgate-Palmolive Company Antibacterial antiplaque oral composition mouthwash or liquid dentifrice
JP2700070B2 (ja) * 1988-06-10 1998-01-19 株式会社資生堂 グラム陽性嫌気性細菌用抗菌剤及びそれを用いた皮膚外用剤、口腔用組成物
DE69119605D1 (de) * 1990-11-12 1996-06-20 Fileco Sa Antivirale verwendung einer in position-4 substituierten 2,6-di-t-butylphenolverbindung, besonders gegen herpes- und papillomaviren
AU9179791A (en) * 1990-12-19 1992-07-22 Procter & Gamble Company, The Oral compositions effective against plaque and gingivitis

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5043154A (en) * 1987-01-30 1991-08-27 Colgate-Palmolive Co. Antibacterial, antiplaque, anticalculus oral composition
FR2646601A1 (fr) * 1989-05-08 1990-11-09 Beecham Inc Dentifrice et compositions orales utiles pour inhiber les calculs dentaires
WO1992000721A1 (en) * 1990-07-13 1992-01-23 The Procter & Gamble Company Anticalculus/antiplaque compositions using azacycloalkane diphosphonates
EP0492998A1 (en) * 1990-12-20 1992-07-01 Colgate-Palmolive Company Anticalculus oral compositions

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2289392C2 (ru) * 2002-05-10 2006-12-20 Колгейт-Палмолив Компани Антибактериальное средство для чистки зубов со свойствами против зубного налета и для освежения дыхания
RU2309929C2 (ru) * 2005-11-15 2007-11-10 Институт Молекулярной Генетики Российской Академии Наук (Имг Ран) Высокомеченный тритием хлорогексидин
RU2414209C2 (ru) * 2006-05-01 2011-03-20 Колгейт-Палмолив Компани Композиция с силиконовым композитом для ухода за полостью рта
RU2505798C2 (ru) * 2008-04-04 2014-01-27 Колгейт-Палмолив Компани Анализ субстратов, на которые нанесены агенты
US8803095B2 (en) 2008-04-04 2014-08-12 Colgate-Palmolive Company Analysis of substrates having agents deposited thereon
US8895929B2 (en) 2008-04-04 2014-11-25 Colgate-Palmolive Company Analysis of substrates having agents deposited thereon
RU2509553C2 (ru) * 2009-06-03 2014-03-20 Колгейт-Палмолив Компани Композиции на основе бориновой кислоты
US8852559B2 (en) 2009-06-03 2014-10-07 Colgate-Palmolive Company Borinic compositions
RU2429884C1 (ru) * 2010-06-28 2011-09-27 Общество С Ограниченной Ответственностью "Акцент" Композиция для получения антисептического средства (варианты) и способ ее применения

Also Published As

Publication number Publication date
CA2232838A1 (en) 1997-03-27
AU708974B2 (en) 1999-08-19
MX9802188A (es) 1998-07-31
CN1200025A (zh) 1998-11-25
JPH11511473A (ja) 1999-10-05
BR9610562A (pt) 1999-07-06
CN1088579C (zh) 2002-08-07
CO4770945A1 (es) 1999-04-30
AU7075996A (en) 1997-04-09
WO1997010800A2 (en) 1997-03-27
ZA967841B (en) 1998-03-17
US5723500A (en) 1998-03-03
EP0852486A2 (en) 1998-07-15
WO1997010800A3 (en) 1997-05-22

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Effective date: 20030919