CN1088579C - 抗牙斑口用组合物 - Google Patents

抗牙斑口用组合物 Download PDF

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Publication number
CN1088579C
CN1088579C CN96197795A CN96197795A CN1088579C CN 1088579 C CN1088579 C CN 1088579C CN 96197795 A CN96197795 A CN 96197795A CN 96197795 A CN96197795 A CN 96197795A CN 1088579 C CN1088579 C CN 1088579C
Authority
CN
China
Prior art keywords
tert
butyl
antibacterial
acid
antiplaque
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN96197795A
Other languages
English (en)
Chinese (zh)
Other versions
CN1200025A (zh
Inventor
O·D·斯特林格
J·C·比拉姆斯
M·素拉曼尼安
E·E·克利
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Colgate Palmolive Co
Original Assignee
Colgate Palmolive Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Colgate Palmolive Co filed Critical Colgate Palmolive Co
Publication of CN1200025A publication Critical patent/CN1200025A/zh
Application granted granted Critical
Publication of CN1088579C publication Critical patent/CN1088579C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/347—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
    • C07C39/14—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings with at least one hydroxy group on a condensed ring system containing two rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
    • C07C39/15—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings with all hydroxy groups on non-condensed rings, e.g. phenylphenol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
    • C07C39/17—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings containing other rings in addition to the six-membered aromatic rings, e.g. cyclohexylphenol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/26—Phenanthrenes; Hydrogenated phenanthrenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN96197795A 1995-09-22 1996-09-18 抗牙斑口用组合物 Expired - Fee Related CN1088579C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US419695P 1995-09-22 1995-09-22
US60/004,196 1995-09-22

Publications (2)

Publication Number Publication Date
CN1200025A CN1200025A (zh) 1998-11-25
CN1088579C true CN1088579C (zh) 2002-08-07

Family

ID=21709632

Family Applications (1)

Application Number Title Priority Date Filing Date
CN96197795A Expired - Fee Related CN1088579C (zh) 1995-09-22 1996-09-18 抗牙斑口用组合物

Country Status (12)

Country Link
US (1) US5723500A (enExample)
EP (1) EP0852486A2 (enExample)
JP (1) JPH11511473A (enExample)
CN (1) CN1088579C (enExample)
AU (1) AU708974B2 (enExample)
BR (1) BR9610562A (enExample)
CA (1) CA2232838A1 (enExample)
CO (1) CO4770945A1 (enExample)
MX (1) MX9802188A (enExample)
RU (1) RU2170079C2 (enExample)
WO (1) WO1997010800A2 (enExample)
ZA (1) ZA967841B (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR199801528T2 (xx) * 1996-02-08 1998-11-23 Warner-Lambert Company Y�ksek derecede ��z�n�r pirofosfat i�eren, di� ta��na kar�� etkili di� temizli�i bile�imi.
US5851513A (en) * 1998-02-03 1998-12-22 Colgate Palmolive Company Antiplaque oral composition and method
US5998487A (en) * 1998-04-08 1999-12-07 Colgate-Palmolive Company Anti-inflammatory and antibacterial benzyl phenol agents and their use in oral compositions
US6113884A (en) * 1998-11-13 2000-09-05 Colgate-Palmolive Company Mixed surfactant, high foaming dentifrice exhibiting enhanced antibacterial compound uptake on dental tissue
US6403652B1 (en) * 2000-06-30 2002-06-11 Colgate-Palmolive Company Method and composition
US6753451B2 (en) * 2000-08-28 2004-06-22 Ciba Specialty Chemicals Corporation Process for the preparation of phenylphenol compounds
AU2002223966A1 (en) 2000-12-20 2002-07-01 Warner Lambert Company Non-halogenated naphthol compounds and antimicrobial compositions containing the same
WO2002050002A1 (en) * 2000-12-20 2002-06-27 Warner-Lambert Company Llc Non-halogenated phenyl substituted phenols, antimicrobial compositions containing the same, and methods of using the same
US20030207945A1 (en) * 2001-12-20 2003-11-06 Harper David Scott Non-halogenated phenyl substituted phenols, antimicrobial compositions containing the same, and methods of using the same
AU2002223958A1 (en) 2000-12-20 2002-07-01 Warner-Lambert Company Llc Non-halogenated phenoxy and/or benzyloxy phenols and antimicrobial compositions containing them
AU2002347508A1 (en) * 2001-12-20 2003-07-09 Warner-Lambert Company Llc Non-halogenated hydroxyalkyl-substituted phenol compounds, antimicrobial compositions containing the same, and methods of using the same
US7402416B2 (en) * 2002-05-10 2008-07-22 Colgate-Palmolive Company Antibacterial dentifrice exhibiting antiplaque and breath freshening properties
US20050255054A1 (en) * 2004-04-30 2005-11-17 Philp Graham K Jr Method for tooth whitening, in particular a system for tooth whitening using a dissolvable tray or strip
EP1776083A4 (en) * 2004-07-02 2010-06-02 Discus Dental Llc SENSITIVITY-RELATED TOOTH COMPOSITIONS
US20060140881A1 (en) * 2004-12-22 2006-06-29 Guofeng Xu Oral care compositions containing flavonoids and flavans
US8895084B2 (en) 2004-12-23 2014-11-25 Colgate-Palmolive Company Oral care composition containing extract of unoxidized Camellia
US20060141039A1 (en) * 2004-12-23 2006-06-29 Colgate-Palmolive Company Oral compositions containing oxidized camellia
US8119169B2 (en) * 2004-12-28 2012-02-21 Colgate-Palmolive Company Oregano oral care compositions and methods of use thereof
US8071077B2 (en) 2004-12-29 2011-12-06 Colgate-Palmolive Company Oral compositions containing biphenol antibacterial compounds
US20060140883A1 (en) * 2004-12-29 2006-06-29 Colgate-Palmolive Company Oral care compositions containing a eucalyptus extract
US8425881B2 (en) 2005-03-18 2013-04-23 Colgate-Palmolive Company Antibacterial 3′,5-disubstituted 2,4′-dihydroxybiphenyl compounds, derivatives and related methods
BRPI0608631A2 (pt) 2005-03-18 2010-11-30 Colgate Palmolive Co composição oral antiplaca, pasta de dentes ou composição em gel, e, método para inibir crescimento bacteriano na cavidade oral de um animal
RU2309929C2 (ru) * 2005-11-15 2007-11-10 Институт Молекулярной Генетики Российской Академии Наук (Имг Ран) Высокомеченный тритием хлорогексидин
US20070190090A1 (en) * 2006-02-07 2007-08-16 Whitehill Oral Technologies, Inc. Sialagogue based oral care products
US9649513B2 (en) * 2006-03-24 2017-05-16 Colgate—Palmolive Company Aerosol dispenser
CA2649481C (en) * 2006-05-01 2012-08-07 Colgate-Palmolive Company Oral care composition with silicone composite
US9682256B2 (en) * 2006-07-14 2017-06-20 Colgate-Palmolive Company Methods of making compositions comprising films
TWI420093B (zh) * 2008-04-04 2013-12-21 Colgate Palmolive Co 一種用以原位測量沉積在一基材上之來自一牙膏的一口腔劑的方法及一種評估一口腔傳送系統之有效性的方法
TW201110996A (en) * 2009-06-03 2011-04-01 Colgate Palmolive Co Borinic compositions
CN102781898B (zh) * 2009-11-05 2014-12-24 菲布他丁有限合伙公司 使用q2拟肽的gpbp抑制
RU2429884C1 (ru) * 2010-06-28 2011-09-27 Общество С Ограниченной Ответственностью "Акцент" Композиция для получения антисептического средства (варианты) и способ ее применения
CN104411287A (zh) 2012-06-29 2015-03-11 高露洁-棕榄公司 包含微晶纤维素和羧甲基纤维素的高水含量口腔组合物
US20200375949A1 (en) * 2017-11-22 2020-12-03 The Trustees Of The University Of Pennsylvania Bisphenol compounds

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH558342A (de) * 1968-08-28 1975-01-31 Sandoz Ag Verfahren zur herstellung von neuen phenolderivaten.
US3800051A (en) * 1970-09-21 1974-03-26 Dow Chemical Co Reducing serum cholesterol with certain substituted phenols
FR2128026A1 (en) * 1971-03-01 1972-10-20 Soredev 3,4-dimethyl-6-(2,4,4-trimethylpent-2-yl) phenol - with antibacterial activity, prepn
FR2165741A1 (en) * 1971-12-28 1973-08-10 Etu Therapeutique Bureau Cyclopent(en)yl-dialyl-phenols - with bactericidal/bacteriostatic and fungicidal/fungistatic activity
US4321257A (en) * 1974-07-08 1982-03-23 Johnson & Johnson Potentiated medicaments
JPS5929161B2 (ja) * 1978-12-05 1984-07-18 味の素株式会社 揮発性防菌防黴製剤
US5043154A (en) * 1987-01-30 1991-08-27 Colgate-Palmolive Co. Antibacterial, antiplaque, anticalculus oral composition
US5188821A (en) * 1987-01-30 1993-02-23 Colgate-Palmolive Company Antibacterial antiplaque oral composition mouthwash or liquid dentifrice
JP2700070B2 (ja) * 1988-06-10 1998-01-19 株式会社資生堂 グラム陽性嫌気性細菌用抗菌剤及びそれを用いた皮膚外用剤、口腔用組成物
CA2016221C (en) * 1989-05-08 1998-07-07 Nader Ibrahim Compositions
HUT63323A (en) * 1990-07-13 1993-08-30 Procter & Gamble Composition against dental deposits, comprissing azacycloalkane diphosphonates
US5208009A (en) * 1990-12-20 1993-05-04 Colgate-Palmolive Company Anticalculus oral compositions
DE69119605D1 (de) * 1990-11-12 1996-06-20 Fileco Sa Antivirale verwendung einer in position-4 substituierten 2,6-di-t-butylphenolverbindung, besonders gegen herpes- und papillomaviren
AU9179791A (en) * 1990-12-19 1992-07-22 Procter & Gamble Company, The Oral compositions effective against plaque and gingivitis

Also Published As

Publication number Publication date
CA2232838A1 (en) 1997-03-27
AU708974B2 (en) 1999-08-19
MX9802188A (es) 1998-07-31
CN1200025A (zh) 1998-11-25
JPH11511473A (ja) 1999-10-05
BR9610562A (pt) 1999-07-06
CO4770945A1 (es) 1999-04-30
AU7075996A (en) 1997-04-09
WO1997010800A2 (en) 1997-03-27
ZA967841B (en) 1998-03-17
US5723500A (en) 1998-03-03
RU2170079C2 (ru) 2001-07-10
EP0852486A2 (en) 1998-07-15
WO1997010800A3 (en) 1997-05-22

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C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C19 Lapse of patent right due to non-payment of the annual fee
CF01 Termination of patent right due to non-payment of annual fee