RU2162334C1 - Homeopathic drug for treatment of patient with osteoarticular pathology (osteoarthrosis, osteochondrosis, arthrosis, arthritis) - Google Patents

Abstract

FIELD: medicine, homeopathy, pharmacy. SUBSTANCE: invention relates to development of homeopathic drug which can be used in osteoarticular pathology (osteoarthrosis, osteochondrosis, arthrosis, arthritis). Composition has the following components: Berberis vulgaris (common barberry), Calcium phosphoricum (calcium phosphate), Solanum dulcamara (bitter-sweet), Rhus toxicodendron (oak-leaved toxicodendron), Causticum (soda caustic) taken in equal ratios and in dilution C12. Composition is the homeopathic drug made as sugar granules. Homeopathic drug shows many-sided effects on body: it normalizes metabolic processes in osseous tissue and articular tissues, improves blood supply of osseous tissue, articular ligamentous apparatus, decreases inflammatory processes in articulations, edema, relieves pain syndrome, improves articulation mobility. Preparation does not cause complications in prolonged using. EFFECT: enhanced effectiveness of preparation, valuable medicinal properties. 2 cl, 1 ex

Description

 The invention relates to medicine, namely to the creation of a homeopathic medicine intended for the treatment of osteoarticular pathology (osteoarthritis, osteochandrosis, arthrosis, arthritis).

 Medicine is constantly looking for ways to combat diseases of the spine and joints. A huge arsenal of drugs, therapeutic baths, massage, manual therapy, acupuncture are included in the complex treatment. Nevertheless, the problem of treating osteochandrosis, polyarthritis, arthrosis remains not completely resolved. Moreover, the long-term use of non-steroid drugs and glucocorticoids causes a number of serious complications, such as osteoparosis, ulceration of the gastric mucosa, intestines.

In joint pathology, the following drugs are most often used:
Apis X3,6,12
Bryonia X3,6,12
Rhus toxicodendron X3,6,12 etc. (A. Krylova, "Homeopathy for general practitioners").

It is known that Berberis vulgaris (Barberry vulgaris), Calcium phosphoricum (Calcium phosphate) - improve metabolism in bone and articular tissue;
Solanum dulcamara (Bitter nightshade), Rhus toxicodendron (Toxicodendron dubifolia) - have anti-inflammatory effects, reducing swelling, pain, improving range of motion.

 Causticum (Causticum) - improves metabolic processes in tissues, improves blood circulation in bone tissue and nerve endings, reduces pain.

 The objective of the present invention is to provide a new homeopathic preparation with a wide range of pharmacological effects, namely, to normalize metabolic processes in the bone and articular tissues to improve blood circulation, reduce inflammation in the joints, swelling, to reduce pain and reduce complications with prolonged use.

The problem is solved by creating a homeopathic preparation that includes the components: Berberis vulgaris (Barberry ordinary), Calcium phosphoricum (Calcium phosphate), Solanum dulcamara (nightshade bittersweet), Rhus toxicodendron (oak-leaved toxicodendron), Causticum (Causticum) taken ratio and dilution C12. The tool is made in the form of sugar granules. The product is called "Lumbosan"
The technology for obtaining homeopathic granules of the composition: Berberis vulgaris (Barberry ordinary) C12, Calcium phosphoricum (calcium phosphate) C12, Solanum dulcamara (Solanum bittersweet) C12, Rhus toxicodendron (Toxicodendron oak-leaved) C12, Causticum (causticum stage: C12,
analysis of matrix tinctures, substances, preparation of homeopathic dilutions, preparation of a complex of homeopathic dilutions, application of a complex of homeopathic dilutions on sugar grits, drying, packaging, packaging, labeling, production control.

 The technology for producing sugar granules is common.

 The invention is illustrated by the following example.

Example
Per 100 g of granules take:
Berberis vulgaris (Barberry vulgaris) C12 - 0.25 g
Solanum dulcamara (Bitter nightshade) C12 - 0.25 g
Rhus toxicodendron (Toxicodendron oak-leaved) C12 - 0.25 g
Causticum (Causticum) C12 - 0.25 g
Calcium phosporicum (Calcium Phosphate) C12 - 0.25 g
Excipients (Sugar grains according to GOST 7060-79) - Up to 100.0 g
The quality of the drug is ensured by compliance with all standards, the requirements for the production of homeopathic granules and the control of the matrix tinctures included in the preparation: Berberis vulgaris (Barberry vulgaris). Calcium phosphoricum (Calcium phosphate), Solanum dulcamara (Bitter nightshade), Rhus toxicodendron (Toxicodendron oak-leaved), Causticum (Causticum), which is included in the technological regulations.

 Analysis of matrix tinctures includes qualitative reactions to the main biological active substances, tests by thin-layer chromatography, determination of density, solids and, if necessary, the quantitative content of active substances.

 Pharmacological action: normalizes metabolic processes in bone and articular tissues, improves their blood supply, reduces inflammation in the joints, swelling, relieves pain.

 The pharmacological action of the granules is due to their constituent components.

According to the literature [1,2,3,4] the active substances of the incoming components are:
Berberis vulgaris (Barberry vulgaris).

 Applicable part: root bark.

 Chemical composition: alkaloids: berberine, palmitin, columbamine, ricin, oxyakontin.

 Application in homeopathy: with urate diathesis, rheumatism, gout, gallstone and urolithiasis, normalization of metabolic processes in the joint and bone tissue.

 Solanum dulcamara (Bitter nightshade).

 Applicable part: the whole plant before flowering with young shoots and leaves.

 Chemical composition: dulcamarin glycoside, solapidine, tannin.

 Use in homeopathy: for rheumatism with exacerbations in cold, wet weather. Ostechandrosis with stiffness. Inflammatory processes in the joints.

 Rhus toxicodendron (Toxicodendron oak-leaved).

 Applicable part: fresh leaves.

 Chemical composition: tannins, mucus, starch.

 Application in homeopathy: with osteochandrosis of the spine, ischalgia, rheumatoid polyarthritis. It has a powerful anti-inflammatory effect.

 Calcium phosphoricum (Calcium phosphate) - precipitated calcium phosphate.

 Applicable material: calcium phosphate powder in the form of trituration 1: 100.

Chemical composition: phosphoric lime CaHPO ₄ · 2H ₂ O.

 Use in homeopathy: for diseases of bones and joints, (rheumatic, metabolic), osteochandrosis.

 Causticum (Causticum) - caustic soda.

 Applicable material: caustic soda 1: 100.

Chemical composition: Na ₂ CO ₃ · 10H ₂ O.

(sodium carbonate crystalline hydrate)
Use in homeopathy: chronic rheumatism, osteoarthritis, sciatica, spinal osteochandrosis with a feeling of numbness and weakness in the limbs, improves blood circulation in the joints.

 Samples of homeopathic granules "Lumbosan" were laid in storage in the package and under the conditions provided for by the VFS project. For 2.5 years, the drug meets all the requirements of the VFS project; observation of the drug during storage continues.

 The shelf life of homeopathic granules "Lumbosan" is set to 2 years.

 The sections "Packaging", "Labeling", "Transportation" are given in accordance with the documentation currently in force.

Mode of application
Granules "are applied orally in 7 granules 20 minutes before meals or 1 hour after meals, 2 times a day. The granules are kept in the mouth until completely dissolved. In acute cases, at the beginning of the disease, it is possible to take every 4 hours, but no more than 5 doses, subsequently take 2 times a day
Clinical trials of the drug were conducted on the basis of the Homeopathic Medical and Social Center and the Regional Gerontological Center in the framework of the program "Senior Generation" adopted by the Administration of the Novosibirsk Region (Decree No. 241 of April 15, 1999). Under observation were 150 patients with deforming osteoarthrosis of large joints, 70 patients with diffuse osteochandrosis, 20 of them expressed symptoms of ischalgia. This group of patients was forced to take non-steroidal anti-inflammatory drugs (indomethacin, diclofenac) before treatment with Lumbosan.

 Rheumatoid polyarthritis, a proliferative form, was diagnosed in 5 patients. This group of patients took corticosteroid therapy.

 The average age of the observed patients is 60-75 years.

 "Lumbosan" was used in patients with rheumatoid polyarthritis in complex therapy. In patients with osteoarthritis and osteochardrosis of the spine was used independently.

 Treatment efficacy was evaluated after 8 weeks of observation.

 In 76% of patients, persistent improvement was noted: pain in the joints and spine disappeared, joint swelling disappeared, range of motion increased, weakness and stiffness in the limbs disappeared. Patients completely refused to take non-steroidal anti-inflammatory drugs.

 24% showed improvement, which allowed to reduce the dose of non-steroidal drugs and corticosteroids. Subsequently, this group took combined allopathic and homeopathic therapy.

 The use of the homeopathic medicine "Lumbosan" has a versatile effect on the body: it normalizes metabolic processes in bone tissue and joint tissues, improves blood supply to bone tissue, ligaments of the joints, reduces inflammation in the joints, swelling, alleviates pain, improves joint mobility. "Lumbosan" does not cause complications with prolonged use, since the components included in the drug are used in small doses, in a potentiated state. The rather low price of the drug makes it affordable for a wide number of patients, and in particular socially unprotected groups of the population.

Literature
1. Vavilova N.M. Homeopathic pharmacodynamics. In 2 parts. Smolensk: Homeopathic center. - M .: Everest, 1994.

 2. Karhut V.V. Faces near us. - Kiev: "Health". 1978.

 3. Mishchenko B. C., Ivanova A.M. Homeopathic medicines (a guide for doctors and pharmacists). - M.: Moscow Homeopathic Center, 1995.

 4. Homoeopathic Materia Medica William Boericke, New Delhi, 1991.

 5. The State Pharmacopoeia of the USSR. XI ed., Vol. 1,2.

 6. OST 42-1-71.

 7. Kiseleva T. D., Karpeev A.A. et al. "Homeopathy and herbal medicine in the treatment of cardiovascular diseases." - M., 1997.

 8. Minaev V. G. Medicinal plants of Siberia. - Novosibirsk: "Science", 1991.

 9. Popov A. P. Herbalist. Kemerovo: Kemerovo Book Publishing House JSC, 1993.

 10. Hering C. Materia Medica New Delhi, 1988.

 11. Homoopathisches Arzneibuch-1 Ausgabe - 1978. - Gesatausgabe. - HAB 1, 1978. 1 Nachtrag 1981; 2 Nachtrag 1983; 3 Nachtrag 1985. - Deutscher Apotheker Verlag Stuttgart Govi-Verlag Gmbh, Frankfurt.

 12. Homoeopathic Repetitorium. Dr. Willmar Schwabe, Karlsrune (Germany), 1994 Edition.

 13. Lilienthal S Homoeopathic Therapeutics New Delhi, 1992.

 14. Pharmacopee Francaise X edotion. Supplement: Monographies de soushes pour preparation homeopathiques. - Paris, 1989.

Claims (1)

 Homeopathic medicine used for bone-articular pathology (osteoarthrosis, osteochandrosis, arthrosis, arthritis), characterized in that it contains: Berberis vulgaris (Barberry vulgaris), Calcium phosphoricum (Calcium phosphate), Solanum dulcamara (Solanum bittersweet) Rhus toxicodendron (Toxicodendron oak-leaved), Causticum (Causticum), taken in equal proportions when diluting C12.