RU2142289C1 - Tonic agent "narkoton" used for treatment of patients with alcoholic dependence - Google Patents

Abstract

FIELD: medicine, narcology, phytotherapy. SUBSTANCE: invention relates to curative preparations of the plant origin and can be used for prophylaxis and treatment of alcoholism. Preparations show tonic and cleansing effects. The preparation has thyme herb, yellow poppy herb and inflorescences, Leuzea carthamoides rhizomes, bear berry herb, centaury herb, tansy inflorescences, European wild ginger herb, common wormwood herb, Saint-John's-wort herb and senna leaves taken at the definite ratio. The use of an agent "Narkoton" shows not only psychomatic effect but psychological one also that results to the complete refusal alcoholic drinks using often. EFFECT: enhanced effectiveness of an agent. 1 cl

Description

 The invention relates to medicine, namely to narcotic drugs of plant origin, and can be used for the treatment and prevention of alcoholism with a tonic and cleansing effect.

 As a result of the study of the most effective narcotic drugs from plant materials in medical practice, it was found that they, often difficult to tolerate by the human body, cause abdominal pain, fainting, and poor blood supply to vital organs.

 Known collection for the treatment of alcohol dependence, containing, for example, 2 herbs of centaury, wormwood, common goldenrod, rosemary, ram, grass and inflorescences of yellow fly, elecampane root, European claw, curly sorrel root and rhizome, blue rhizome blue, and the raw material is ground to size particles 500-750 microns (see patent PU N 2043114, class A 61 K 35/78, publ. 09/10/95).

 Known herbal remedy "NARCODEL" for the treatment of alcohol dependence, which by its purpose and combination of components is the closest analogue to the claimed, as it contains thyme grass 15-25 g, grass and inflorescences yellow fly 15-25 g, safflower rhizome rhizome 8- 15 g, 8-15 g centaury grass, bearberry grass 8-15 g, tansy inflorescences 8-15 g, wormwood grass 8-15 g, European ungulate grass 5-10 g. The mass is ground to a particle size of 500-750 μm (cm patent RU N 2040271, class A 61 K 35/78, publ. 07.25.95).

 However, with good tolerance of known analogous agents and persistence of the therapeutic effect, treatment with known agents proceeds for a rather long time, since detoxification of the body during the treatment period is slow. This is due to the components that are part of these agents, which have a choleretic and antiseptic effect, and alcoholics, as a rule, have a lot of somatic disorders against metabolic disorders, which leads to a decrease in bowel function and the secondary absorption of alcohol with putrefactive fermentation products, i.e. . to autointoxication of the body.

 The objective of the invention is to create means to reduce the time period from taking the drug to the onset of the desired anti-alcohol effect by accelerating the removal of decay products and alcohol from the body, as well as increasing the vitality of a person during and after treatment.

 To solve the problem in the claimed drug "NARCOTON" in addition to signs similar to those of the closest analogue (N 2), this is the presence in the collection of thyme herb 0.03-0.06 g, grass and inflorescence yellow fly 0.03-0.06 g, rhizome rhizome safflower 0.01-0.04 g, centaury grass 0.01-0.04 g, bearberry grass 0.01-0.04 g, tansy inflorescences 0.01-0.04 g, wormwood grass 0 , 01-0.04 g, European ungulates grass 0.01-0.04 g introduced new, distinctive components from the analogue: St. John's wort grass 0.92-1.27 g, senna leaf 0.01-0.04 g.

 In the analysis of the prior art, no technical solutions for the treatment of alcohol dependence have been identified, which have the same characteristics that are identical to all components contained in the claims of the claimed invention, and therefore it follows that the tonic "NARCOTON" for the treatment of alcohol dependence meets the novelty condition.

 The analysis of other drugs and drugs for the treatment of alcohol dependence, known in literary sources, in medicine and in folk medicine, showed that they lack the new distinguishing features that are present in the formula of the claimed invention - this is the presence of St. John's wort and senna leaf in a new quantitative range of values specified in the claims, in connection with which the tonic "NARCOTON" meets the condition of an inventive step.

 Therefore, the claimed tonic "NARCOTON" for the treatment of alcohol dependence, having novelty, inventive step and the possibility of use in any treatment and prevention conditions, is patentable.

The raw materials were taken at a single dose in the optimal average unit value of each of the components (ingredients), grinding them to a particle size of 450-800 microns, depending on the type of raw material, weight in grams per dose:
Thyme (herb) - 0.04
Sack yellow (grass and inflorescences) - 0.04
Safflower Leuzea (rhizome) - 0.02
Centaury (grass) - 0.02
Bearberry (grass) - 0.02
Tansy (inflorescences) - 0.02
Wormwood (grass) - 0.02
European ungulates (grass) - 0.02
St. John's wort (grass) - 0.98
Senna (leaf) - 0.02
Next, the collected fee is packaged in disposable packages. It can be disposable, easily soluble powders with the extract of all medicinal ingredients, granules, capsules or compressed dosage tablets. A disposable bag is brewed in 200 ml of boiling water, insisted for 20-30 minutes. Take the infusion once a day, most effective before bedtime.

 The tonic "NARCOTON", the components of which are taken as an example in average unit values, gives a positive clinical result of the cure for alcohol without any side effects. The claimed range of quantitative values is optimal to achieve a positive effect from the use of the drug "NARCOTON", the novelty and effectiveness of the cure for alcoholism are provided due to the introduction of St. John's wort in the amount of 0.92 - 1.27 g and senna leaf in the amount of 0.01 - 0.04 g, which, together with thyme, wormwood, centaury, tansy, yellow spotter, with anti-inflammatory, choleretic and antiseptic effects on the liver and gastrointestinal tract, bearberry, with with a urethic effect that removes toxins from the body, safflower levzea, which has a tonic effect, as well as European ungulates, which reduce the craving for alcohol, provide a complete wellness complex for alcohol and human organs, since St. John's wort, having a strong tonic and antidepressant effect, removes the condition anxiety in humans, increases the vitality of blood vessels of the whole organism, and senna leaves, causing a laxative effect, accelerate the output of decay products from the body, by direct reduced time period from the reception means before the desired effect.

 Due to the fact that alcohol belongs to the group of sedative-hypnotic drugs and is on a par with barbiturates and tranquilizers, its effect in itself causes lethargy and drowsiness, i.e. inhibition of the cerebral cortex. When you get out of a state of intoxication, a person becomes depressed. St. John's wort, possessing an antidepressant property, in the amount of 0.92 - 1.27 g relieves depression, increases vascular tone and improves the general condition of a person suffering from alcoholism.

 In the process of an alcoholic state, the decay products of alcohol, oxidized by special enzymes, are removed from the body through the kidneys, skin, lungs, intestines. When the body forces are used to remove these toxins, the work of the gastrointestinal tract, as a rule, slows down, and toxins that are trapped in the intestine are again absorbed into the blood, poisoning the human body. Senna leaves taken in an amount of 0.01 - 0.4 g exclude the retention of toxins in the intestine, thereby contributing to a regular laxative effect, there is an accelerated removal of decay products from the body and an improvement in the general state of human health, which, in turn, reduces the time period taking a tonic up to the desired effect.

 The use of the Narcoton tonic for the treatment of alcohol addiction enhances the renewal of the human body, reduces the time period from taking the drug to the desired effect by accelerating the removal of toxins from the body, improves the functions of the liver, gastrointestinal tract, sleep, endocrine glands, most quickly reduces the craving for alcohol, aggressiveness, irritation and asthenoneurotic manifestations. In addition, not only a psychosomatic effect is achieved, but also a psychological one, such as social adaptation, increasing self-esteem, eliminating anosognosia, improving mnemonic data, and often completely abandoning alcoholic beverages.

Claims (1)

A tonic for the treatment of alcohol addiction, including herbs of thyme, centaury, wormwood, bearberry, European ungulate, grass and inflorescences of yellow fly, rhizome of safflower-like and tansy inflorescences, characterized in that it additionally contains St. John's wort grass and senna leaves in the following ratio of components, weight in grams per dose:
Thyme herb - 0.03 - 0.06
Yellow grass and inflorescences yellow fly - 0.03 - 0.06
Rhizome of Leuzea safflower - 0.01 - 0.04
Bearberry grass - 0.01 - 0.04
Centaury grass - 0.01 - 0.04
Tansy inflorescences - 0.01 - 0.04
European Clefthoof Grass - 0.01 - 0.04
Wormwood Grass - 0.01 - 0.04
St. John's wort grass - 0.92 - 1.27
Senna leaf - 0.01 - 0.04