RU2139708C1 - Ointment "zvar" for treatment of suppurative and infected wounds of different etiology - Google Patents

Abstract

FIELD: medicine, pharmacy. SUBSTANCE: invention proposes an ointment containing pine galipot and/or spruce galipot, bee wax, butter, vegetable oil, inner fats, propolis and onion taken at the definite amounts. An ointment exhibits the increased spectrum of curative effect. EFFECT: enhanced therapeutic effectiveness, decreased treatment period. 3 ex

Description

 The invention relates to medicine, in particular to therapeutic ointments of anti-inflammatory action with biostimulating properties for the treatment of purulent-inflammatory processes of the skin and mucous membranes, cuts, otitis media, tonsillitis, mastitis, erosion of the cervix, burns, felon, psoriasis, herpes, dermatitis, allergic rashes, etc.

 Known ointment "Benin" for the treatment of purulent and infected wounds of various etilogy, consisting of fir oil, propolis, coniferous resin, spermaceti and penguin fat in a mass ratio of components 3 - 7: 0.5 - 1.5: 0.5 - 1, 5: 1.5 - 2.5: 7 - 15, respectively (see RF Patent N 2058776, CL A 61 K 9/06, 1995).

 However, this known ointment contains penguin fat, the availability and raw material base of which is limited.

 Closest to the proposed invention by technical essence is the anti-inflammatory ointment "Pihtoin" containing in wt.%: 19.0 - 21.0 pine resin; 16.8-17.5 beeswax; 10.5-12.0 chalk; fat base - industrial oil - the rest (see RF Patent N 2097056, class A 61 K 35/78, A 61 K 9/06, from 1995).

 The disadvantage of this known ointment is that it contains industrial oil as a fat base, which limits the scope of this ointment to veterinary medicine only.

 In addition, a known ointment has limited therapeutic efficacy.

 The aim of the invention is to increase the therapeutic effectiveness of the ointment by increasing the range of therapeutic effects and reducing the duration of treatment.

 An additional goal is to expand the range of medicinal ointments while ensuring the availability and scarcity of the raw material base.

This goal is achieved by the fact that the well-known ointment for the treatment of purulent and infected wounds of various etilogies, containing coniferous resins, beeswax, a fat base and an additive, contains pine resin and / or spruce resin as pine resin, and butter as a fat base, vegetable oil, interior pork fat and / or interior beef fat and / or interior goose fat and / or interior sheep fat, and as an additive, the ointment contains propolis and turnip in the following ratio of ingredients, wt.%:
Resin resin and / or spruce resin - 7.0 - 8.0
Beeswax - 6.7 - 7.3
Butter - 6.5 - 7.5
Vegetable oil - 6.5 - 7.5
Interior pork fat and / or interior beef fat, and / or interior goose fat, and / or interior sheep fat - 19.0 - 22.0
Propolis - 0.5 - 1.0
Turnip Onion - Else
From the patent and scientific and technical literature, we do not know therapeutic ointments containing the combination of the above ingredients in the proposed quantitative ratio, which allows us to conclude that the claimed technical solution is new.

 Achieving this goal is due to the fact that the proposed ointment has a multifaceted effect: antimicrobial, analgesic, osmotic, due to biologically active substances extracted from propolis, beeswax, coniferous resins, turnip onion and a fatty base of complex composition.

 An ointment of this composition allows you to effectively act on purulent and infected wounds of various etilogies, up to a complete cure in a short time.

The following substances were used to prepare the proposed Zvar ointment:
- pine resin and / or spruce spruce according to OST 13-128-82;
- beeswax according to GOST 21179-75;
- butter in accordance with GOST 37-91;
- vegetable oil in accordance with GOST 1129-93;
- interior cleaned pork fat;
- interior cleaned beef fat;
- interior goose fat refined;
- Sheep interior fat purified;
- chopped onion.

 The proposed ointment is prepared as follows.

 7.5 g of pork interior fat, 6.5 g of beef interior fat, 5 g of goose’s interior fat, 7.5 g of refined vegetable oil, 6.5 g of melted butter, 7 g of beeswax are added to the container, and the resulting mixture is melted. Then 7 g of pine resin is added to the melt and everything is thoroughly mixed. Then, 0.5 g of propolis and 52.5 g of chopped onion are added to the resulting mixture. The mixture is again heated over low heat with stirring and filtered. The result is the inventive ointment "Zvar".

 An ointment with a different content of ingredients is prepared in a similar way.

 The ointment is stored in a glass dish in a dark, cool place for up to 5 years without loss of initial activity.

Ointment "Zvar" at room temperature is a homogeneous composition of a solid consistency, yellow in color with a pleasant smell of coniferous resins. When in contact with the body or heating above ± 25-30 ^o C, the ointment becomes fluid and plastic. It does not dissolve in water and alcohol. The ointment is non-toxic.

 Contraindication to use is individual intolerance (allergy).

 Ointment use: before using the ointment, wash the wound with an antiseptic solution, apply the ointment with a thin layer (≈ 2 mm) on a gauze towel folded in two layers and put on the wound, then strengthen the cloth with the ointment with a bandage or a patch. Change the dressing with ointment is necessary 1 - 2 times a day.

 Example 1. Patient Loginov A. 8 months. Penetrating wound of the cheek, obtained from a puncture with a fork from the inside of the mouth. The patient underwent surgical treatment, antibiotics were prescribed, dressings with Vishnevsky ointment were applied, but this did not have a positive effect, the wound was suppurated, and persistent swelling of the cheek was maintained. The child was exhausted by the pain of the wound and the practical lack of sleep. Only two weeks later he was given a bandage with Zvar ointment, at which time antibiotics were not used. The first dressings after removal were abundantly saturated with purulent contents. At the end of the second day, the wound cleansed of pus, swelling disappeared. On the fourth day, the wound completely closed. No allergies were observed.

 Example 2. Patient Kamenkova I. 36 years. I was treated for psoriasis for one year with various medications, including ointments: ichthyol, sulfur-tar, salicylic, fluorocort, but no lasting positive effect was observed. She began to apply the Zvar ointment, a month later completely disappeared papules with a diameter of up to 2 cm, "plaques" in their place also resolved, the skin turned pinkish, the itching disappeared. No allergies were observed.

 Example 3. Patient Sukhikh V. 23 years. Panaritium of the nail index finger of the right hand: there was a sharp pain in the area of the nail, aggravated by pressure on it, redness of the skin of the finger, swelling. Without surgical treatment, a bandage with Zvar ointment was applied, after 24 hours the pain disappeared, and pus flowed out onto the bandage. Dressings changed 2 times a day. After 2 days, a full recovery came. No allergies were observed.

 Example 4. Patient Tretyakova L. 25 years. Purulent lactational mastitis. Breast drainage was done on both sides, antibiotics were prescribed. Applying dressings with Vishnevsky ointment for 2 days did not give a positive result. Then a bandage with Zvar ointment was applied, purulent contents expired after 8 hours, chest swelling disappeared, and the temperature decreased. After 3 days, the painful symptoms disappeared, on the fifth day the wounds from drainage completely closed, and a full recovery began. An allergic reaction was not observed.

 Treatment with ointment "Zvar" in almost all cases took place with a positive result, accelerated wound healing was observed without complications and side effects.

 The use of the proposed ointment for the treatment of wounds of various etilogy showed the stimulating effect of the ointment on the regenerative processes of connective tissue and epithelium, which indicates the biostimulating effect of the ointment and is confirmed by a reduction in the healing time of wounds.

 Thus, the proposed ointment accelerates the rejection of necrotic tissue of the wounds, reduces the healing time and stimulates the development of young granulation tissue with acceleration of its maturation, enhances the proliferation of the epithelium.

Claims (1)

An ointment for the treatment of purulent and infected wounds of various etiologies containing an active substance, coniferous resins, beeswax, a fat base, characterized in that the ointment contains propolis and onion as an active substance, contains pine gum and / or gum as pine gum. ate, as a fat base - butter, vegetable oil, interior pork fat and / or interior beef fat, and / or interior goose fat, and / or interior sheep fat in the following ratio of ingredients, wt.%:
Gum pine and / or gum spruce - 7.0 - 8.0
Beeswax - 6.7 - 7.3
Butter - 6.5 - 7.5
Vegetable oil - 6.5 - 7.5
Interior pork fat, and / or interior beef fat, and / or interior goose fat, and / or interior sheep fat - 19.0 - 22.0
Propolis - 0.5 - 1.0
Turnip Onion - Else