RU2106154C1 - Wound dressing material - Google Patents

Abstract

FIELD: medicine, in particular, material for treating burns. SUBSTANCE: material is constituted from polyethylene film which surface has coating consisting of 95% talcum and 5% mixture of medicinal preparations. Mixture is additionally contains KERATAN biopreparation powder based on water-soluble keratin. Mixture of medicinal preparations contains components taken in equal weight ratio. Film is perforated with rows of openings forming plurality of continuous rectangles which sides are equal to 100 and 200 mm. Openings are made rectangular with sides equal to 1 mm and 3-5 mm, and are spaced apart at a distance 1 mm. Material offers multiple advantages: improved properties in use, accelerated healing of burn wounds, reduced time treatment. Autodermosplasty operation is dispensed, and skin surface area can be considerably reduced by 2-3 times. EFFECT: higher healing properties.

Description

 The invention relates to medicine, specifically to the production of dressings that can be used to treat burns.

 With traditional methods of treating burns, local treatment is started after the patients are taken out of shock with a toilet on the burned areas of the body. It is performed in the operating room after preliminary administration of pain medications to the patient. The skin around the burn is wiped with napkins moistened with 0.5% ammonia solution or soapy water, dried and treated with alcohol. Then a gauze ball moistened with a solution of antiseptic or 0.25% solution of novocaine removes foreign bodies from the burnt surface, scraps of the epidermis. After the toilet, burns are treated with wet-drying and ointment dressings ("Big Medical Encyclopedia", M., Publishing House "Soviet Encyclopedia", 1981, v. 17, p. 231).

 The use of traditional dressings in the treatment of burns requires the preparation of burned surfaces before dressing, the use of painkillers in the toilet of wounds, as these procedures are very painful, dressings dry to the surface of the wounds, injure granulation and young epithelium, wound infection is often observed. Healing is accompanied by skin scars and scarring.

 Known dressing material DDB (dressing, dressing dr. R. Breitman), made of plastic film with Breitman complex powder applied on its surface. Breitman powder is a mixture of 95% talc and 5% powders of drugs taken in equal proportions: cephalolexin, streptomycin, erythromycin, terramycin, tetracycline, vibromycin, syntomycin, neomycin, kanamycin, nystatin, dactarin, canesten and rivanol. (Abstracts of reports of the International Surgical Congress. "Wounds, burns, dressings," Israel, Tel Aviv, 1990, pp. 86-87 and 114).

 The well-known film dressing material DDB is free from the disadvantages of traditional dressings, since special moist conditions are created under the film, which contribute to the dissolution of the necrotic layers of the surface of a deep burn. Necrotic crusts do not form, the burn surface does not dry out and the lesion does not deepen. Dressings are painless, painkillers are not required, local treatment of the affected surface begins immediately, since no preparation of the wound surface is required to apply a film dressing.

 Under film dressings with a mixture of drugs, the healing of burns is much faster and the healing time is shortened by about 40% compared with treatment with traditional dressings. When using film dressings for the treatment of extensive burns, the loss of protein and fluid through the surface of the burn is reduced, and the burn wound does not become infected. These conditions allow for burns of degree 3AB to avoid the operation of skin transplantation, which is necessary with traditional skin treatments.

The disadvantages of the known dressings include:
1) the lack of drainage ability, as in cases of abundant discharge from the wound surface, the patient feels certain inconvenience when using film dressing due to leakage of these discharge from under the film;
2) the inability to do without skin transplant surgery for burns of degree 3B.

 The invention solves the problem of creating a film dressing material with improved performance properties, accelerating the healing of burn wounds, reducing the time of their treatment, and also allowing to exclude the operation of autodermoplasty or significantly reduce (by 2-3 times) the operating area.

 The problem is solved due to the fact that in the dressing made of a polyethylene film with 95% talcum powder and 5% mixture of drugs applied on one side, the mixture additionally contains Keratan biological powder based on water-soluble keratin with an equal ratio of components in the mixture drugs, and the film contains rows of holes forming rectangles of a continuous surface with side sizes of 100 and 200 mm, while the holes are made rectangular with side sizes of 1 and 3-5 mm per 1mm on standing.

 The proposed perforated dressing DDB-MK (dressing, dressing, dr. Breitman - dr. Menzul - Keratan) is non-toxic, does not cause allergies, protects the wound from infection from the outside, is non-invasive, does not cause secondary necrosis, provides a moist environment, in its general the nature close to the composition of the internal environment of the body, stops the development of the microbial process, stimulates regenerative processes in the wound, migration of epithelial cells, promotes edge epithelization, scarless healing of burn wounds of 3-4 degrees, reduction of operas 2-3 times.

 Before applying the proposed dressing material does not require preparation of the burned surface. After opening the package, the material is applied to the wound with an inner surface with a sprayed layer of drugs. Typically, the film adheres well to the wound. For a better fit, 2-4 layers of gauze or bandages are applied over the dressings.

 Bandages are changed first after 24 hours, then after 48 and 72 hours as needed.

 The proposed dressing material can be made of a film of various configurations - sleeves of various diameters, film sheets of various sizes, which are folded along the lines of the holes, which is an additional advantage of the proposed dressing material, as it allows you to compactly pack the dressing material of a large area.

 Upon receipt of the proposed dressing material, talc is used, drugs: cephalolexin, streptomycin, erythromycin, terramycin, tetracycline, vibromycin, synthomycin, neomycin, kanamycin, nystatin, dactarine, canesten, rivinol and Keratan biological product.

 The "Keratan" biological product in powder form is a highly purified water-soluble molecular form of keratin protein with a characteristic set of amino acids. Contains at least 93% keratin protein itself. It is accompanied by bound sulfur - up to 2.5%, total minerals - up to 70%, fats and carbohydrates - up to 0.5%. Highly hygroscopic and adhesive, has good adsorption capacity.

 Keratan is an environmentally friendly product made from benign wool. The release form is a powder from light sand to light cream color with no extraneous odor with a particle size of not more than 0.15 mm. Registration certificate N29-271 from 04/26/95. It is allowed to use in medical practice by order of the Ministry of Health of the Russian Federation N271 dated 12.12.94 (pos. 40).

 The material is prepared as follows.

 A complex Breitman powder is sprayed onto a plastic film containing rows of holes forming rectangular sections of a continuous surface with side sizes of 100 and 200 mm with the size of the sides of the holes being rectangular, 1 and 3-5 mm, and located at a distance of 1 mm from each other. containing "Keratan", so that covering the film with an even layer, it does not crumble due to the forces of electrostatic attraction. A perforated film dressing is obtained, which is folded along the lines of the holes with a sprayed layer inside and sterilized with gamma radiation at a dose of 2.5 Mrad.

 Example. Patient N., age 6 years old, received burns with boiling water of the left lower leg and foot with a lesion area of about 8% of 2, 3A and 3B degrees. Burns of degree 3B were obtained in the rear of the foot. He entered the children's Lyubertsy burn center. Treatment with DDB-M film dressing with keratan was started immediately upon admission. Dressings were carried out as needed, were painless. The wound surface was not infected, antibiotic treatment was not required. There was a complete wound healing without autodermoplasty.

Claims (1)

 Dressing material for the treatment of wounds and burns, made of a polyethylene film with 95% talcum powder and 5% mixture of drugs applied to its surface, characterized in that the mixture additionally contains Keratin biological product powder based on water-soluble keratin with an equal ratio of components in the drug mixture preparations, and the film contains rows of holes forming rectangles of a continuous surface with side sizes of 100 and 200 mm, while the holes are made rectangular with side sizes of 1 and 3 - 5 mm per melting 1 mm.